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The map label for this gene is citZ [H]

Identifier: 73537702

GI number: 73537702

Start: 485031

End: 485810

Strand: Reverse

Name: citZ [H]

Synonym: Reut_B3867

Alternate gene names: 73537702

Gene position: 485810-485031 (Counterclockwise)

Preceding gene: 73537703

Following gene: 73537701

Centisome position: 17.82

GC content: 66.41

Gene sequence:

>780_bases
ATGGTAACGACTGTCAAGACTGAAATCGGCTACACCACCACCGACACGATCATGGTGCGTGGCCTGAACCTCGCCACGGA
GATCATCGGCAAGTTCGATTTTGTCGACATGATCTTCTTCACCACGCTGTCGCGCCTGCCCACGCCGCGCGAGAAGGTCA
TGGTCAACGCCTTGCTGGTGACCACGGCCGACCACGGCATCACGCCGAGTTCGCTGTCGGCCCGCCTGACCTACATCGGC
GCGCCGGAAGCGCTGCAGGGCGCGGTGGCCACCGGCCTGCTCGGCGCGGGCAGCGTATTCCTCGGCCCGATGCAGAATGC
GACCGAGATGCTCAACGAAGGCACGCGCGAACTCAGCGATGACGCCACCGACGAGCAGCTGCTGGAAACCGCCCGCGCGC
TGATCAAGCGCTACAAGGAAAGCCGCCAGCAGGTCTACGGCGTGGGCCATCCGATCCACGTCGATGGCGACCCGCGCGTG
CCGGCGCTGCGCGAGCTGTCGCGCCAGAACGGCTACTACGGCCTGCACTGGCGCCTGATGGAGGCGATCGTCGAGGTGCT
GGTCAAAGAGCAAAAGCGCAAGCTGCCGATGAACGTGGTCGGCGCGATCGGCGCCATCGTCGCCGCGATGGGCCTGGACC
CGCTGATCGCGCGCGGCCTGGCGCTGGTGGGCCGCTCGGCAGGCCTGCTCGCCCACGTACTCGAGGAAAAGCAGGATCCG
ATGGCGCGCGAAGCGTGGCAGCTCGTCCTGAAGGCAGATCCGCGCAACGTGCTGCCCTGA

Upstream 100 bases:

>100_bases
TCGAAGAGCTGGAGATCAACCCCCTCGCGGTGCGTCCGCAGGGTCAGGGAGTGGCTGCGCTGGACGCCGTCCTCTCGTTT
CAGGGCATGGAGCCTTCAAC

Downstream 100 bases:

>100_bases
GGAGACGGGCGCCTATGACGCCGCTGCACGGCGGCGCCTTAGGCGCGTGGGCGGATGACGCGGGCTTTCCGAGCCGTACG
AAATTTCGTATAGTTCCACT

Product: citrate synthase

Products: NA

Alternate protein names: Citrate synthase II [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVTTVKTEIGYTTTDTIMVRGLNLATEIIGKFDFVDMIFFTTLSRLPTPREKVMVNALLVTTADHGITPSSLSARLTYIG
APEALQGAVATGLLGAGSVFLGPMQNATEMLNEGTRELSDDATDEQLLETARALIKRYKESRQQVYGVGHPIHVDGDPRV
PALRELSRQNGYYGLHWRLMEAIVEVLVKEQKRKLPMNVVGAIGAIVAAMGLDPLIARGLALVGRSAGLLAHVLEEKQDP
MAREAWQLVLKADPRNVLP

Sequences:

>Translated_259_residues
MVTTVKTEIGYTTTDTIMVRGLNLATEIIGKFDFVDMIFFTTLSRLPTPREKVMVNALLVTTADHGITPSSLSARLTYIG
APEALQGAVATGLLGAGSVFLGPMQNATEMLNEGTRELSDDATDEQLLETARALIKRYKESRQQVYGVGHPIHVDGDPRV
PALRELSRQNGYYGLHWRLMEAIVEVLVKEQKRKLPMNVVGAIGAIVAAMGLDPLIARGLALVGRSAGLLAHVLEEKQDP
MAREAWQLVLKADPRNVLP
>Mature_259_residues
MVTTVKTEIGYTTTDTIMVRGLNLATEIIGKFDFVDMIFFTTLSRLPTPREKVMVNALLVTTADHGITPSSLSARLTYIG
APEALQGAVATGLLGAGSVFLGPMQNATEMLNEGTRELSDDATDEQLLETARALIKRYKESRQQVYGVGHPIHVDGDPRV
PALRELSRQNGYYGLHWRLMEAIVEVLVKEQKRKLPMNVVGAIGAIVAAMGLDPLIARGLALVGRSAGLLAHVLEEKQDP
MAREAWQLVLKADPRNVLP

Specific function: Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect [H]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 28225; Mature: 28225

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTVKTEIGYTTTDTIMVRGLNLATEIIGKFDFVDMIFFTTLSRLPTPREKVMVNALLV
CCEEEEECCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHE
TTADHGITPSSLSARLTYIGAPEALQGAVATGLLGAGSVFLGPMQNATEMLNEGTRELSD
EECCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
DATDEQLLETARALIKRYKESRQQVYGVGHPIHVDGDPRVPALRELSRQNGYYGLHWRLM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCEEHHHHHH
EAIVEVLVKEQKRKLPMNVVGAIGAIVAAMGLDPLIARGLALVGRSAGLLAHVLEEKQDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
MAREAWQLVLKADPRNVLP
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVTTVKTEIGYTTTDTIMVRGLNLATEIIGKFDFVDMIFFTTLSRLPTPREKVMVNALLV
CCEEEEECCCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHE
TTADHGITPSSLSARLTYIGAPEALQGAVATGLLGAGSVFLGPMQNATEMLNEGTRELSD
EECCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCC
DATDEQLLETARALIKRYKESRQQVYGVGHPIHVDGDPRVPALRELSRQNGYYGLHWRLM
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCEEHHHHHH
EAIVEVLVKEQKRKLPMNVVGAIGAIVAAMGLDPLIARGLALVGRSAGLLAHVLEEKQDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
MAREAWQLVLKADPRNVLP
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045898; 9387221; 9384377 [H]