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The map label for this gene is kdgR [H]

Identifier: 73537701

GI number: 73537701

Start: 484161

End: 484901

Strand: Reverse

Name: kdgR [H]

Synonym: Reut_B3866

Alternate gene names: 73537701

Gene position: 484901-484161 (Counterclockwise)

Preceding gene: 73537702

Following gene: 73537698

Centisome position: 17.79

GC content: 66.53

Gene sequence:

>741_bases
ATGCCCACAATGATTCCTGCCGCCAGCCGAGCCATGGCGGTGTTCGAAGTGTTCGCGCGCGAAAAGCGCGAACTGTCCAA
CTCCGACATGGCACGCCTGCTGTCATTGCCGGAAAGCAGCACCTCCGACCTGTTGCACACCCTGCATTCGCTGGGCTATC
TGATGCGCACGACGCGCACTCGGCGCTTCTATCCCACGGGTCGCCTTTCTGAAATCGCACGGCAGATCGCCGAGAACGAC
CCGCTGACCACCGTGGCGCAGGAAGCCATCGAGCAGGTCAGCGCCAGGACCAACGAGAGCGTCTTCTTCGGCGTGCTCGA
CGGGACCGCGGTCAAGGTCATGGCCGTCCAGGCCAGCCGCCTGCCCCTGCGCTACATCATCGAAGTCGGCTACCGCGCCG
CCCTGCACGCGTCCGCGCTCGGCAAGGGGCTGCTGGGCCTGCTGCCCCCCGAAGAGGCCCGCGAGACACTCGCCAAAAGC
AGCCTGCGCGCCGTCACCGCGCATACGGTCGTCGACATCGACACGCTGATGGCCCAGGTCGCCAAAGGCCGCAAACGCGG
ATGGTACGAGGCGCACGAAGAAGGCAGCGAGGGCGTCCACGGTCTGGCGGTGACGGGCTGGCTGGGTGGCCAGGCTGCCG
GCATCTCGCTGGCGGGGCCTGCCGAGCGCATGAAGAAGAACCACGACGCGTATCTGGCGGCGCTGATCGAGGTGCGGGAT
GCGTTGATGAGCGAGGAGTGA

Upstream 100 bases:

>100_bases
GGCGGCGCCTTAGGCGCGTGGGCGGATGACGCGGGCTTTCCGAGCCGTACGAAATTTCGTATAGTTCCACTGTCCGCTGA
ATCCACCACCTCTGCCAAGC

Downstream 100 bases:

>100_bases
GGGGTGAGGGGTGAGGGGTGAGGGGTGAAGGGTGAAGGGTGAAGGGTGACGAGTGATACCGGGCCGTCCCTTTGCTTGTC
ACGAAGCCTTCCAGGCCATG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPTMIPAASRAMAVFEVFAREKRELSNSDMARLLSLPESSTSDLLHTLHSLGYLMRTTRTRRFYPTGRLSEIARQIAEND
PLTTVAQEAIEQVSARTNESVFFGVLDGTAVKVMAVQASRLPLRYIIEVGYRAALHASALGKGLLGLLPPEEARETLAKS
SLRAVTAHTVVDIDTLMAQVAKGRKRGWYEAHEEGSEGVHGLAVTGWLGGQAAGISLAGPAERMKKNHDAYLAALIEVRD
ALMSEE

Sequences:

>Translated_246_residues
MPTMIPAASRAMAVFEVFAREKRELSNSDMARLLSLPESSTSDLLHTLHSLGYLMRTTRTRRFYPTGRLSEIARQIAEND
PLTTVAQEAIEQVSARTNESVFFGVLDGTAVKVMAVQASRLPLRYIIEVGYRAALHASALGKGLLGLLPPEEARETLAKS
SLRAVTAHTVVDIDTLMAQVAKGRKRGWYEAHEEGSEGVHGLAVTGWLGGQAAGISLAGPAERMKKNHDAYLAALIEVRD
ALMSEE
>Mature_245_residues
PTMIPAASRAMAVFEVFAREKRELSNSDMARLLSLPESSTSDLLHTLHSLGYLMRTTRTRRFYPTGRLSEIARQIAENDP
LTTVAQEAIEQVSARTNESVFFGVLDGTAVKVMAVQASRLPLRYIIEVGYRAALHASALGKGLLGLLPPEEARETLAKSS
LRAVTAHTVVDIDTLMAQVAKGRKRGWYEAHEEGSEGVHGLAVTGWLGGQAAGISLAGPAERMKKNHDAYLAALIEVRDA
LMSEE

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=237, Percent_Identity=23.6286919831224, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786468, Length=208, Percent_Identity=26.4423076923077, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786715, Length=223, Percent_Identity=24.2152466367713, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082359, Length=237, Percent_Identity=23.6286919831224, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26741; Mature: 26610

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTMIPAASRAMAVFEVFAREKRELSNSDMARLLSLPESSTSDLLHTLHSLGYLMRTTRT
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
RRFYPTGRLSEIARQIAENDPLTTVAQEAIEQVSARTNESVFFGVLDGTAVKVMAVQASR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEHEEHHHHH
LPLRYIIEVGYRAALHASALGKGLLGLLPPEEARETLAKSSLRAVTAHTVVDIDTLMAQV
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGRKRGWYEAHEEGSEGVHGLAVTGWLGGQAAGISLAGPAERMKKNHDAYLAALIEVRD
HHHHHCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHH
ALMSEE
HHHCCC
>Mature Secondary Structure 
PTMIPAASRAMAVFEVFAREKRELSNSDMARLLSLPESSTSDLLHTLHSLGYLMRTTRT
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
RRFYPTGRLSEIARQIAENDPLTTVAQEAIEQVSARTNESVFFGVLDGTAVKVMAVQASR
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEHEEHHHHH
LPLRYIIEVGYRAALHASALGKGLLGLLPPEEARETLAKSSLRAVTAHTVVDIDTLMAQV
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGRKRGWYEAHEEGSEGVHGLAVTGWLGGQAAGISLAGPAERMKKNHDAYLAALIEVRD
HHHHHCCCCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHH
ALMSEE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]