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The map label for this gene is yncB [H]

Identifier: 73537687

GI number: 73537687

Start: 467222

End: 468241

Strand: Reverse

Name: yncB [H]

Synonym: Reut_B3852

Alternate gene names: 73537687

Gene position: 468241-467222 (Counterclockwise)

Preceding gene: 73537688

Following gene: 73537686

Centisome position: 17.18

GC content: 63.82

Gene sequence:

>1020_bases
ATGAAGACCATGAACCGGCGCTGGATCCTCAGGCAGCGCCCCGTCGGCGATATCGGCGACAACGATCTGCAGCTCGTGGA
AGCACCGCTGCCTCGACCGGGCGACGGCGAGATCCTGGTGCGCAACATCTATCTCATGGTGGCACCGACCAACCGCGTGT
GGATGAGCGAGATCGACCAGTACATGGCCCCGGTGGCACTTGGCGAGGTGATGCGCGGCGTCACCATGGGCGTGGTGACC
GAGTCCCATCACCCGGACTTCAAGGCCGGTGACATCGTCGAAGGTGGCATGGCGTGGGAGGAGTATTCGGTCACGAAGAT
GGCCCGGCGTGTCCCGGTGGAGTACGGCCTGCCGCTGCATGCCTATGCGAGCGTGCTGGGCAACTCCGGCATGACCGCCT
ATTTCGGCATGCTTGACATTGCCCGGCCCAAGGCTGGCGAGACCATCGTGGTGTCGGCCGCCGCAGGCGGCGTCGGCTCG
ATCGCCGGCCAGATCGGCAAGATACTCGGCTGCCGGGTAGTCGGCGTTGCCGGCGGCCAGAACAAGTGCCGGCTCGTCAG
GGAAGAGTTCGGCCTGGATGCCTGTGTCGATTACAAGGCCGGCAACGTGCTCGCCGATCTTCGCGCCGCCTGTCCGGACG
GCATCGACGTCGATTTCGAGAACGTGGGCGGCGAAACCATGGATGCCGTGCTGGCGCTGATCAACCCGGGAGCGCGTATC
GCGATGTGCGGGATGATCTCCACCTACAACGCGAGCGGCGACTGGTGGAGCCCGAAGATGTTCCGCAATGTCATCATGAA
ACGCGCCCGCATCGAAGGCTTCCTCATTGCCGACTACCGTTCGCGGTTCCACGAAGCCGTGGAAGTCATGGCGAAATGGG
TCAGGGACGGCCAGCTCAAGTATCGGGTCGACATTGTCGAAGGCATCGAGCAGGCACCGGCCGCGCTGAACCGCTTGTTT
ACCGGCAAGAACATCGGCAAGCAGCTTGTGCGCCTGGCGCCGGAATCCGTCATCGGCTAA

Upstream 100 bases:

>100_bases
CATCGTATATGCCGCGCTGGAAGACTGAGCGGCGACGCTTTGCGGCGACTGGCAGTGCAGCACGCACACGGCGCCACGTA
CCAATTTTGGAGGAGCAAGC

Downstream 100 bases:

>100_bases
ATGCCGCGACTCTCACCTGTCAATCTCCATGACTCAATCTGACTCCCGACCGCGCCTTCAGGATTTCGAGGGCAAGACGG
CAATCATCACCGGCGCCGCG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKTMNRRWILRQRPVGDIGDNDLQLVEAPLPRPGDGEILVRNIYLMVAPTNRVWMSEIDQYMAPVALGEVMRGVTMGVVT
ESHHPDFKAGDIVEGGMAWEEYSVTKMARRVPVEYGLPLHAYASVLGNSGMTAYFGMLDIARPKAGETIVVSAAAGGVGS
IAGQIGKILGCRVVGVAGGQNKCRLVREEFGLDACVDYKAGNVLADLRAACPDGIDVDFENVGGETMDAVLALINPGARI
AMCGMISTYNASGDWWSPKMFRNVIMKRARIEGFLIADYRSRFHEAVEVMAKWVRDGQLKYRVDIVEGIEQAPAALNRLF
TGKNIGKQLVRLAPESVIG

Sequences:

>Translated_339_residues
MKTMNRRWILRQRPVGDIGDNDLQLVEAPLPRPGDGEILVRNIYLMVAPTNRVWMSEIDQYMAPVALGEVMRGVTMGVVT
ESHHPDFKAGDIVEGGMAWEEYSVTKMARRVPVEYGLPLHAYASVLGNSGMTAYFGMLDIARPKAGETIVVSAAAGGVGS
IAGQIGKILGCRVVGVAGGQNKCRLVREEFGLDACVDYKAGNVLADLRAACPDGIDVDFENVGGETMDAVLALINPGARI
AMCGMISTYNASGDWWSPKMFRNVIMKRARIEGFLIADYRSRFHEAVEVMAKWVRDGQLKYRVDIVEGIEQAPAALNRLF
TGKNIGKQLVRLAPESVIG
>Mature_339_residues
MKTMNRRWILRQRPVGDIGDNDLQLVEAPLPRPGDGEILVRNIYLMVAPTNRVWMSEIDQYMAPVALGEVMRGVTMGVVT
ESHHPDFKAGDIVEGGMAWEEYSVTKMARRVPVEYGLPLHAYASVLGNSGMTAYFGMLDIARPKAGETIVVSAAAGGVGS
IAGQIGKILGCRVVGVAGGQNKCRLVREEFGLDACVDYKAGNVLADLRAACPDGIDVDFENVGGETMDAVLALINPGARI
AMCGMISTYNASGDWWSPKMFRNVIMKRARIEGFLIADYRSRFHEAVEVMAKWVRDGQLKYRVDIVEGIEQAPAALNRLF
TGKNIGKQLVRLAPESVIG

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=351, Percent_Identity=34.1880341880342, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI226246680, Length=351, Percent_Identity=34.1880341880342, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI22748929, Length=351, Percent_Identity=34.1880341880342, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI226059159, Length=333, Percent_Identity=34.8348348348348, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI226059133, Length=333, Percent_Identity=34.8348348348348, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI226056130, Length=296, Percent_Identity=34.4594594594595, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI28557745, Length=330, Percent_Identity=28.7878787878788, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI18379349, Length=268, Percent_Identity=23.8805970149254, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI226510941, Length=339, Percent_Identity=44.2477876106195, Blast_Score=283, Evalue=8e-78,
Organism=Caenorhabditis elegans, GI133901712, Length=359, Percent_Identity=32.033426183844, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI133901710, Length=359, Percent_Identity=32.033426183844, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323504, Length=368, Percent_Identity=26.0869565217391, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36931; Mature: 36931

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMNRRWILRQRPVGDIGDNDLQLVEAPLPRPGDGEILVRNIYLMVAPTNRVWMSEIDQ
CCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
YMAPVALGEVMRGVTMGVVTESHHPDFKAGDIVEGGMAWEEYSVTKMARRVPVEYGLPLH
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCHHCCCCHH
AYASVLGNSGMTAYFGMLDIARPKAGETIVVSAAAGGVGSIAGQIGKILGCRVVGVAGGQ
HHHHHHCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCC
NKCRLVREEFGLDACVDYKAGNVLADLRAACPDGIDVDFENVGGETMDAVLALINPGARI
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCEE
AMCGMISTYNASGDWWSPKMFRNVIMKRARIEGFLIADYRSRFHEAVEVMAKWVRDGQLK
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHCCCEE
YRVDIVEGIEQAPAALNRLFTGKNIGKQLVRLAPESVIG
EEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MKTMNRRWILRQRPVGDIGDNDLQLVEAPLPRPGDGEILVRNIYLMVAPTNRVWMSEIDQ
CCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
YMAPVALGEVMRGVTMGVVTESHHPDFKAGDIVEGGMAWEEYSVTKMARRVPVEYGLPLH
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCHHCCCCHH
AYASVLGNSGMTAYFGMLDIARPKAGETIVVSAAAGGVGSIAGQIGKILGCRVVGVAGGQ
HHHHHHCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEECCCC
NKCRLVREEFGLDACVDYKAGNVLADLRAACPDGIDVDFENVGGETMDAVLALINPGARI
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCEE
AMCGMISTYNASGDWWSPKMFRNVIMKRARIEGFLIADYRSRFHEAVEVMAKWVRDGQLK
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHCCCEE
YRVDIVEGIEQAPAALNRLFTGKNIGKQLVRLAPESVIG
EEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]