Click here to switch to the map view.

The map label for this gene is tauD [H]

Identifier: 73537682

GI number: 73537682

Start: 462908

End: 463756

Strand: Direct

Name: tauD [H]

Synonym: Reut_B3847

Alternate gene names: 73537682

Gene position: 462908-463756 (Clockwise)

Preceding gene: 73537680

Following gene: 73537683

Centisome position: 16.98

GC content: 65.02

Gene sequence:

>849_bases
ATGCGTGTCGAGCCACTTACCTGTTCCATCGGCGCTGAACTGGTCGGCGTCAGCCTTGCCGATGCCATCCACGATGACGG
CTTGTTCGCCGGCATTCGTGAAGCGCTGCTCAAACATCGTGTCCTGTTCGTGCGCGGGCAGGACATAACCGCCGGCGAGC
ACGTCGCCTTTGCGCGCCGCTTTGGCGAACTGGAAGACCATCCGGTCGCGGGCAGCGATCCCGAACACCCTGGGCTGGTC
CGCATCTACAAGAGCCCCGAAGAGCCCACTCCGCGTTACGAGAATTCCTGGCACACCGATGCGACCTGGCGCGAGGCCCC
GCCGCTCGCCAGCATCCTGCGCTGCCGCGAATGCCCGCCGGTCGGCGGCGACACCATGTGGAGCAATATGGTGCTTGCCT
ACGAGAACCTGCCGCAGCACATCAAGGACCAGATCGCAGGACTGCGCGCGCGCCACAGCATCGAAGCCAGCTTCGGCGCG
GCCATGCCGATCGAAAAACGCCATGCCCTGAGGGCCCAGTTTCCGGACGCCGAGCACCCTGTGGTCCGGACGCATCCCGA
CACCGGCGAGAAGGTGCTGTTCGTAAACGGCTTCACCACCCACTTCACGAACTTCCATACGCCGGAGCACGTGCGCTTCG
GGCAGGACTTCAACCCGGGCGCGGCCGACCTGCTGCGCTACCTGATTACGCAGGCCTACATTCCCGAGTACCAGGTGCGC
TGGCGCTGGACGCCGAACAGCGTGGCGATCTGGGACAACCGCTCGACCCAGCATTACGCGGTCATGGACTACCCGCCATG
CCATCGCCGGATGGACCGTGCCACGGTGATCGGGGATCGCCCGTTCTGA

Upstream 100 bases:

>100_bases
AAGTCACTGCCCCGGAATGTCAACGCATCGCGCGCCGCCTCTTCAATACTTGCATCGACCCTTTTGCTTCGGCCTCTACC
TACAATCTTTCGGAGTCGCA

Downstream 100 bases:

>100_bases
GCGGCACGCCCCTTCATGCTTCCCCATTGCAACGCAAACCAGACTGAGACACTGACAATGAGCCAGATCGACCCCAACCT
GCTCAAGGACAAGGTTGCCG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRVEPLTCSIGAELVGVSLADAIHDDGLFAGIREALLKHRVLFVRGQDITAGEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPEEPTPRYENSWHTDATWREAPPLASILRCRECPPVGGDTMWSNMVLAYENLPQHIKDQIAGLRARHSIEASFGA
AMPIEKRHALRAQFPDAEHPVVRTHPDTGEKVLFVNGFTTHFTNFHTPEHVRFGQDFNPGAADLLRYLITQAYIPEYQVR
WRWTPNSVAIWDNRSTQHYAVMDYPPCHRRMDRATVIGDRPF

Sequences:

>Translated_282_residues
MRVEPLTCSIGAELVGVSLADAIHDDGLFAGIREALLKHRVLFVRGQDITAGEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPEEPTPRYENSWHTDATWREAPPLASILRCRECPPVGGDTMWSNMVLAYENLPQHIKDQIAGLRARHSIEASFGA
AMPIEKRHALRAQFPDAEHPVVRTHPDTGEKVLFVNGFTTHFTNFHTPEHVRFGQDFNPGAADLLRYLITQAYIPEYQVR
WRWTPNSVAIWDNRSTQHYAVMDYPPCHRRMDRATVIGDRPF
>Mature_282_residues
MRVEPLTCSIGAELVGVSLADAIHDDGLFAGIREALLKHRVLFVRGQDITAGEHVAFARRFGELEDHPVAGSDPEHPGLV
RIYKSPEEPTPRYENSWHTDATWREAPPLASILRCRECPPVGGDTMWSNMVLAYENLPQHIKDQIAGLRARHSIEASFGA
AMPIEKRHALRAQFPDAEHPVVRTHPDTGEKVLFVNGFTTHFTNFHTPEHVRFGQDFNPGAADLLRYLITQAYIPEYQVR
WRWTPNSVAIWDNRSTQHYAVMDYPPCHRRMDRATVIGDRPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=290, Percent_Identity=40.6896551724138, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6322971, Length=294, Percent_Identity=27.891156462585, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 32014; Mature: 32014

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEPLTCSIGAELVGVSLADAIHDDGLFAGIREALLKHRVLFVRGQDITAGEHVAFARR
CCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKSPEEPTPRYENSWHTDATWREAPPLASILRCRECPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
VGGDTMWSNMVLAYENLPQHIKDQIAGLRARHSIEASFGAAMPIEKRHALRAQFPDAEHP
CCCCHHHHCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
VVRTHPDTGEKVLFVNGFTTHFTNFHTPEHVRFGQDFNPGAADLLRYLITQAYIPEYQVR
EEEECCCCCCEEEEEECCHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEE
WRWTPNSVAIWDNRSTQHYAVMDYPPCHRRMDRATVIGDRPF
EEECCCCEEEECCCCCCEEEEECCCHHHHHCCCCEEECCCCC
>Mature Secondary Structure
MRVEPLTCSIGAELVGVSLADAIHDDGLFAGIREALLKHRVLFVRGQDITAGEHVAFARR
CCCCCEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHH
FGELEDHPVAGSDPEHPGLVRIYKSPEEPTPRYENSWHTDATWREAPPLASILRCRECPP
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
VGGDTMWSNMVLAYENLPQHIKDQIAGLRARHSIEASFGAAMPIEKRHALRAQFPDAEHP
CCCCHHHHCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
VVRTHPDTGEKVLFVNGFTTHFTNFHTPEHVRFGQDFNPGAADLLRYLITQAYIPEYQVR
EEEECCCCCCEEEEEECCHHHCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEEE
WRWTPNSVAIWDNRSTQHYAVMDYPPCHRRMDRATVIGDRPF
EEECCCCEEEECCCCCCEEEEECCCHHHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]