BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 73537669

GI number: 73537669

Start: 447338

End: 448249

Strand: Direct

Name: ucpA [C]

Synonym: Reut_B3834

Alternate gene names: 73537669

Gene position: 447338-448249 (Clockwise)

Preceding gene: 73537668

Following gene: 73537670

Centisome position: 16.41

GC content: 66.01

Gene sequence:

>912_bases
ATGAGCTTGCTAGAAGGAAAGGTTGTCATTGTGACCGGCGCAGGCGCCGGTGTCGGCAAGGGTATCGCCATGGAAGCGGC
GCGCCAGGGCGCGCGCGTGATCGTGAACGATCTCGGCGTGGCCATCGACGGCTCGGGCGGCAGCGCCGGTCCCGCGCAGC
AGACCGTGGACGAGATCAAGGCGCTCGGCGGCGAAGCCGCGGCCAACACCGACAGCGTGGCGGACTGGGAATCGGCCCAG
AAGATCGCCCAGCAGGCCATGGACCTGTACGGCCGCATCGACGGCGTGGTGAACAACGCCGGCAACCTGCGCGACGTCAT
GTTCCACAAGATGAGCGAGGAAGAATTCGACTCCGTGATCCGCGTGCACCTGAAGGGCACCTGGAACGTGTCGCGCGCCG
TCGCCCCGCACTTCAAGGCGCAGGAAAGCGGTGCCTACGTGCACATGACGTCGACGTCGGGCCTGATCGGCAACGTGGGC
CAGGCCAACTACGCCGCCGCGAAGATGGGCATCGTCGGCCTGTCTAAGTCGATCGCGCTCGACATGAAGAAGTTCAACGT
GCGTTCGAACTGCATCGCGCCGTTCGCGTTCACGCGCATGGTCGGCAGCATCCCGGCCAACACGCCGGAGGCCGTGGAGC
GCATGAAGATCCATATGCGCATGGAGCCGGGCAAGATCGCCCCGTTCACGCTGGCGCTGCTGACCGACCAGGCCAAGGAT
GTCAACGGCCAGATCTTCGGCGTGCGCAGCAACGAGATCTACCTGATGTCGCAGCCGCGCCCGATCCGCACCGCCCACAA
CGACCAGGGCTGGACCGTGGAGAGTTGCCTGGAGCGCGCGATCCCGATGTTCCGTCCCTCGCTGTTCCCGCTGGATCTCT
CGCGCGACGCGTTCGCCTGGGACCCGGTCTGA

Upstream 100 bases:

>100_bases
CGCCGGTGCCGCTGCCAGCGGGGCACCGGCCGTGCTGTCCGGACGCTGCCTTGTGAAATCCGGTTCCTGAAGAATTCTTT
GACAGTAGTGGAGACACAGC

Downstream 100 bases:

>100_bases
GCATTGCCACGGGGGTAGTAGCTGGTGGCCGGCCGCTGGGGGGCGGCTGGCCACCATGTTGGATGACAAGGAAGAGACAT
GGATTTTCAGCCTGACCTCA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSLLEGKVVIVTGAGAGVGKGIAMEAARQGARVIVNDLGVAIDGSGGSAGPAQQTVDEIKALGGEAAANTDSVADWESAQ
KIAQQAMDLYGRIDGVVNNAGNLRDVMFHKMSEEEFDSVIRVHLKGTWNVSRAVAPHFKAQESGAYVHMTSTSGLIGNVG
QANYAAAKMGIVGLSKSIALDMKKFNVRSNCIAPFAFTRMVGSIPANTPEAVERMKIHMRMEPGKIAPFTLALLTDQAKD
VNGQIFGVRSNEIYLMSQPRPIRTAHNDQGWTVESCLERAIPMFRPSLFPLDLSRDAFAWDPV

Sequences:

>Translated_303_residues
MSLLEGKVVIVTGAGAGVGKGIAMEAARQGARVIVNDLGVAIDGSGGSAGPAQQTVDEIKALGGEAAANTDSVADWESAQ
KIAQQAMDLYGRIDGVVNNAGNLRDVMFHKMSEEEFDSVIRVHLKGTWNVSRAVAPHFKAQESGAYVHMTSTSGLIGNVG
QANYAAAKMGIVGLSKSIALDMKKFNVRSNCIAPFAFTRMVGSIPANTPEAVERMKIHMRMEPGKIAPFTLALLTDQAKD
VNGQIFGVRSNEIYLMSQPRPIRTAHNDQGWTVESCLERAIPMFRPSLFPLDLSRDAFAWDPV
>Mature_302_residues
SLLEGKVVIVTGAGAGVGKGIAMEAARQGARVIVNDLGVAIDGSGGSAGPAQQTVDEIKALGGEAAANTDSVADWESAQK
IAQQAMDLYGRIDGVVNNAGNLRDVMFHKMSEEEFDSVIRVHLKGTWNVSRAVAPHFKAQESGAYVHMTSTSGLIGNVGQ
ANYAAAKMGIVGLSKSIALDMKKFNVRSNCIAPFAFTRMVGSIPANTPEAVERMKIHMRMEPGKIAPFTLALLTDQAKDV
NGQIFGVRSNEIYLMSQPRPIRTAHNDQGWTVESCLERAIPMFRPSLFPLDLSRDAFAWDPV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=43.4959349593496, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI15277342, Length=223, Percent_Identity=31.8385650224215, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=27.0588235294118, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4758504, Length=220, Percent_Identity=33.1818181818182, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=195, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI83715985, Length=196, Percent_Identity=33.1632653061224, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI19923817, Length=204, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=27.9693486590038, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI59889578, Length=166, Percent_Identity=28.3132530120482, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=23.9583333333333, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=35.0194552529183, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=31.7460317460317, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=32.8, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=29.6875, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787526, Length=257, Percent_Identity=28.4046692607004, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=27.8350515463918, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082160, Length=216, Percent_Identity=25.462962962963, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786812, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=25.6916996047431, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=25.0965250965251, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789057, Length=185, Percent_Identity=26.4864864864865, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=42.3387096774194, Blast_Score=186, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.0677290836653, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=32.6693227091633, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=210, Percent_Identity=28.0952380952381, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567345, Length=180, Percent_Identity=27.2222222222222, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=220, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=220, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=24.7104247104247, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=213, Percent_Identity=27.2300469483568, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=214, Percent_Identity=30.8411214953271, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=25.2918287937743, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=243, Percent_Identity=45.2674897119342, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324126, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=40.2542372881356, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=36.0323886639676, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI23397609, Length=199, Percent_Identity=33.6683417085427, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17737361, Length=218, Percent_Identity=30.7339449541284, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=25.8883248730964, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640492, Length=206, Percent_Identity=25.7281553398058, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=28.2828282828283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364892, Length=195, Percent_Identity=27.1794871794872, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355631, Length=203, Percent_Identity=25.615763546798, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=25.5102040816327, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=26.4550264550265, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=199, Percent_Identity=24.1206030150754, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32445; Mature: 32313

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLEGKVVIVTGAGAGVGKGIAMEAARQGARVIVNDLGVAIDGSGGSAGPAQQTVDEIK
CCCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHHHH
ALGGEAAANTDSVADWESAQKIAQQAMDLYGRIDGVVNNAGNLRDVMFHKMSEEEFDSVI
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCEE
RVHLKGTWNVSRAVAPHFKAQESGAYVHMTSTSGLIGNVGQANYAAAKMGIVGLSKSIAL
EEEECCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCHHHHH
DMKKFNVRSNCIAPFAFTRMVGSIPANTPEAVERMKIHMRMEPGKIAPFTLALLTDQAKD
HHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCEEEEEEECCCCC
VNGQIFGVRSNEIYLMSQPRPIRTAHNDQGWTVESCLERAIPMFRPSLFPLDLSRDAFAW
CCCEEEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCC
DPV
CCC
>Mature Secondary Structure 
SLLEGKVVIVTGAGAGVGKGIAMEAARQGARVIVNDLGVAIDGSGGSAGPAQQTVDEIK
CCCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHHHH
ALGGEAAANTDSVADWESAQKIAQQAMDLYGRIDGVVNNAGNLRDVMFHKMSEEEFDSVI
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCEE
RVHLKGTWNVSRAVAPHFKAQESGAYVHMTSTSGLIGNVGQANYAAAKMGIVGLSKSIAL
EEEECCCCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCHHHHH
DMKKFNVRSNCIAPFAFTRMVGSIPANTPEAVERMKIHMRMEPGKIAPFTLALLTDQAKD
HHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCEEEEEEECCCCC
VNGQIFGVRSNEIYLMSQPRPIRTAHNDQGWTVESCLERAIPMFRPSLFPLDLSRDAFAW
CCCEEEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCC
DPV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]