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The map label for this gene is mmlH [H]

Identifier: 73537604

GI number: 73537604

Start: 366539

End: 367840

Strand: Direct

Name: mmlH [H]

Synonym: Reut_B3769

Alternate gene names: 73537604

Gene position: 366539-367840 (Clockwise)

Preceding gene: 73537603

Following gene: 73537609

Centisome position: 13.45

GC content: 65.28

Gene sequence:

>1302_bases
ATGTTTGACTGGTTCCGCGATTTGTCGCGCATGGAGCGCAAGGGCTTCTATGGCGCTTTCCTAGGACATGCGGTCGATGT
ATTCGACTTCATGATCTATTCCTTCCTCATCTCCACGCTGCTGGGGCAGTGGGGCATGAGCAAGTCGACCGCGGGCGCTA
TCGTCACGTGGACGCTGGTGTCGTCGCTGGTCGGCGCGATCGGGGCCGGCATCCTGGCCGACCGCTACGGCCGCGTGCGG
GTGCTGCGCTGGACCATTATCGTGTTCGCCATCGCCTGCTTCCTGTGCGGGCTGGCGCAGTCACCGGAACAACTCATGCT
GTTCCGCATGATCCAGGGCCTGGGCTTCGGCGGCGAATCGTCGCTGTGCATGGTGCTGGTGACGGAGATGATCCGCAACC
CCGCGCATCGCGGCAAATACTCGGGCTTCACCGCGAGCAGCTACTCGTTCGGCTGGGGCGCGGCGGCGATCGTCTACGCG
CTCACGTTCAGCATGCTGCCGGCCGAAACGGCGTGGCGCGTCTGCTTCTTCCTCGGCATCCTGCCCGCACTGGTGGTGAT
CTACCTGCGCCGCAATCTGGAGGAGCCAGAGGTATTCCTGAAGAGCCGCGCGGCTGGCCGGCAGGGGACGGCGCTGGCAG
GCCTGGGCCGGCTGTTCCGTGGTCCGCTGCTGTCCAAGACCCTGCTGTGCAGTCTGCTCTCGGGCGGCATGCTCGGTGCG
TACTACGCGATCGCCACGTGGCTGCCGACCTTCCTCAAGACCGAGCGCGGGCTATCGGTGTTCGGCACCAGTTCCTATCT
GGCGGTGACGATCATCGGGTCACTGATCGGCTATGTGGCGGGCGCCTACGCGACGGATCGCTGGGGCCGCAGGCTGACCT
ATATCGTGTTCGCGGCGGGGGCCTTCGTGGCCGCGCTGGTCTATATGGTGATCCCGGTGTCGAACACGTCGATGCTGTTC
CTCGGCTTCCCGCTGGGGATCCTGATGCAGGGCGTATTCTCGGGCATCGGCGCGACGATTTCGGAATCGTTTCCCAACGA
TATCCGTGCGACGGGATACGGCGTGTCGTACAACGCCGGGCGCGTGATCGGCTCGCTGTTCCCGCTGTCGGTGGGGTGGC
TGAGTTCCGGGCACACGTCTTTGCCGACCGCGATTGCGATTGTCGCCGGGGTGGGCTACGTGATGGTCGTGATGGCCGCG
CTGCTGCTGCCCGAGACGACCGGGATGGATCTCGGACAGGCTGGCGGTGGAGAAGAGCAGGATTCGGCGCCGCTGGCGCA
ACCCGCGGGGACAGTCGCCTGA

Upstream 100 bases:

>100_bases
TCGAAGACGCAGGCTACGCTTTCCGGCCACCGCCGCGGCCGTCCACGCTGCCGGCGAACCTCCACCACTAAGACCCCCAC
ACACAACATAGGGAGGGATC

Downstream 100 bases:

>100_bases
AGCCGTTCGTTCGCGGGCCGCGAACGCGATACGTGTGTCGTGCCTGGGCCTGCAGCGCCAGGCCGTGCTGTTGCCGGGAG
CAGGATGCCGAACGCTTCAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFDWFRDLSRMERKGFYGAFLGHAVDVFDFMIYSFLISTLLGQWGMSKSTAGAIVTWTLVSSLVGAIGAGILADRYGRVR
VLRWTIIVFAIACFLCGLAQSPEQLMLFRMIQGLGFGGESSLCMVLVTEMIRNPAHRGKYSGFTASSYSFGWGAAAIVYA
LTFSMLPAETAWRVCFFLGILPALVVIYLRRNLEEPEVFLKSRAAGRQGTALAGLGRLFRGPLLSKTLLCSLLSGGMLGA
YYAIATWLPTFLKTERGLSVFGTSSYLAVTIIGSLIGYVAGAYATDRWGRRLTYIVFAAGAFVAALVYMVIPVSNTSMLF
LGFPLGILMQGVFSGIGATISESFPNDIRATGYGVSYNAGRVIGSLFPLSVGWLSSGHTSLPTAIAIVAGVGYVMVVMAA
LLLPETTGMDLGQAGGGEEQDSAPLAQPAGTVA

Sequences:

>Translated_433_residues
MFDWFRDLSRMERKGFYGAFLGHAVDVFDFMIYSFLISTLLGQWGMSKSTAGAIVTWTLVSSLVGAIGAGILADRYGRVR
VLRWTIIVFAIACFLCGLAQSPEQLMLFRMIQGLGFGGESSLCMVLVTEMIRNPAHRGKYSGFTASSYSFGWGAAAIVYA
LTFSMLPAETAWRVCFFLGILPALVVIYLRRNLEEPEVFLKSRAAGRQGTALAGLGRLFRGPLLSKTLLCSLLSGGMLGA
YYAIATWLPTFLKTERGLSVFGTSSYLAVTIIGSLIGYVAGAYATDRWGRRLTYIVFAAGAFVAALVYMVIPVSNTSMLF
LGFPLGILMQGVFSGIGATISESFPNDIRATGYGVSYNAGRVIGSLFPLSVGWLSSGHTSLPTAIAIVAGVGYVMVVMAA
LLLPETTGMDLGQAGGGEEQDSAPLAQPAGTVA
>Mature_433_residues
MFDWFRDLSRMERKGFYGAFLGHAVDVFDFMIYSFLISTLLGQWGMSKSTAGAIVTWTLVSSLVGAIGAGILADRYGRVR
VLRWTIIVFAIACFLCGLAQSPEQLMLFRMIQGLGFGGESSLCMVLVTEMIRNPAHRGKYSGFTASSYSFGWGAAAIVYA
LTFSMLPAETAWRVCFFLGILPALVVIYLRRNLEEPEVFLKSRAAGRQGTALAGLGRLFRGPLLSKTLLCSLLSGGMLGA
YYAIATWLPTFLKTERGLSVFGTSSYLAVTIIGSLIGYVAGAYATDRWGRRLTYIVFAAGAFVAALVYMVIPVSNTSMLF
LGFPLGILMQGVFSGIGATISESFPNDIRATGYGVSYNAGRVIGSLFPLSVGWLSSGHTSLPTAIAIVAGVGYVMVVMAA
LLLPETTGMDLGQAGGGEEQDSAPLAQPAGTVA

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=387, Percent_Identity=26.6149870801034, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87082231, Length=460, Percent_Identity=26.9565217391304, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1790550, Length=428, Percent_Identity=26.1682242990654, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081723, Length=320, Percent_Identity=27.5, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082159, Length=438, Percent_Identity=27.1689497716895, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46218; Mature: 46218

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWFRDLSRMERKGFYGAFLGHAVDVFDFMIYSFLISTLLGQWGMSKSTAGAIVTWTLV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SSLVGAIGAGILADRYGRVRVLRWTIIVFAIACFLCGLAQSPEQLMLFRMIQGLGFGGES
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
SLCMVLVTEMIRNPAHRGKYSGFTASSYSFGWGAAAIVYALTFSMLPAETAWRVCFFLGI
HHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LPALVVIYLRRNLEEPEVFLKSRAAGRQGTALAGLGRLFRGPLLSKTLLCSLLSGGMLGA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHH
YYAIATWLPTFLKTERGLSVFGTSSYLAVTIIGSLIGYVAGAYATDRWGRRLTYIVFAAG
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AFVAALVYMVIPVSNTSMLFLGFPLGILMQGVFSGIGATISESFPNDIRATGYGVSYNAG
HHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCHHHHHCCCCCHHHCCCCCCCCHH
RVIGSLFPLSVGWLSSGHTSLPTAIAIVAGVGYVMVVMAALLLPETTGMDLGQAGGGEEQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DSAPLAQPAGTVA
CCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]