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The map label for this gene is pcaR [H]

Identifier: 73537536

GI number: 73537536

Start: 286378

End: 287184

Strand: Direct

Name: pcaR [H]

Synonym: Reut_B3701

Alternate gene names: 73537536

Gene position: 286378-287184 (Clockwise)

Preceding gene: 73537529

Following gene: 73537537

Centisome position: 10.5

GC content: 65.3

Gene sequence:

>807_bases
ATGAACCTGCCCGTCGAACAATTCATTGCCGAGCGCCGCCGCGAAGACCCGTCTTTCGGGGGGCTGCTGGCCAAAGGCTT
TGCCCTGCTGCGCTGCTTTATCGACGAGCCGCGGCCGCTTGGCAATGGCGAACTCGCGCAGCGGCTGCAGCTGCCGCGCG
CGACGGTATCGCGCATCTGCCGCACGCTGTTCGAGCTTGGCTATCTCGACTGGGATCCCAAGCTCGACAAGTATTTCGTC
AGCGCCCAGGTGCTCGCGCTCGGCTATCCGTACCTGACCGGCCTGCAAGTCCGCCACGTGGCCCGTCCGCTGATGCAGGC
GCTGGCCGACCGCATCGAAGGCGCGGTGTCGATGGGTGTGGCGCACCGGCTCGACGTGACCTATCTGCAGTCCTGCACCC
ACAACGAAGGGACGCCGGCCAGACCCGGTACCGGCGCCGTGCGCTCGGTGCTTAGTACGGCCATGGGGCGTGCCTATCTG
TGCACCTTGTCAAAGGCCGAGTTTGAAAGCCTGATGACCTCCGCAAGCGAGGAGCGGCCGGAGGAATACGCCGCGTTCTA
CGACACGCTGTGCCACAACGTCGCCCACTACCCGAAGCGCGGCTTTGCGCTCAACGAGGGCGATGCCGGCATTGGCGTGC
ATGGCGTGGGGGTCTATTCGCGCATCCGCTACCTGAACCGTCCGCTGCTGTTCAACTGCGCCTTGCCTGGCTCGCAGGTC
AGGCGCGGGACCATGGAAAAGAAGATCGCGCCGCTGCTGATGGAAATGGTCCGCTCCATCGAGGCGGCCACCGGCCTGCA
GCAATAG

Upstream 100 bases:

>100_bases
ACGGGTCAAGGCGATGACCTATATTTCCAACATCTGGAAATGGATTCCACGTTTTGACACTGGGCGCCTCCGTGTCCAGA
CTGGATAGAGAGGAAACACC

Downstream 100 bases:

>100_bases
CGGCTGACGCCCAACATCCACAACAAGACCCGCATTGGAGACGCTCGTATGGTTGACCTGAATTCCCTGCTGTATCCGCG
TTCGATCGCCGTGATTGGTG

Product: regulatory protein IclR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNLPVEQFIAERRREDPSFGGLLAKGFALLRCFIDEPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWDPKLDKYFV
SAQVLALGYPYLTGLQVRHVARPLMQALADRIEGAVSMGVAHRLDVTYLQSCTHNEGTPARPGTGAVRSVLSTAMGRAYL
CTLSKAEFESLMTSASEERPEEYAAFYDTLCHNVAHYPKRGFALNEGDAGIGVHGVGVYSRIRYLNRPLLFNCALPGSQV
RRGTMEKKIAPLLMEMVRSIEAATGLQQ

Sequences:

>Translated_268_residues
MNLPVEQFIAERRREDPSFGGLLAKGFALLRCFIDEPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWDPKLDKYFV
SAQVLALGYPYLTGLQVRHVARPLMQALADRIEGAVSMGVAHRLDVTYLQSCTHNEGTPARPGTGAVRSVLSTAMGRAYL
CTLSKAEFESLMTSASEERPEEYAAFYDTLCHNVAHYPKRGFALNEGDAGIGVHGVGVYSRIRYLNRPLLFNCALPGSQV
RRGTMEKKIAPLLMEMVRSIEAATGLQQ
>Mature_268_residues
MNLPVEQFIAERRREDPSFGGLLAKGFALLRCFIDEPRPLGNGELAQRLQLPRATVSRICRTLFELGYLDWDPKLDKYFV
SAQVLALGYPYLTGLQVRHVARPLMQALADRIEGAVSMGVAHRLDVTYLQSCTHNEGTPARPGTGAVRSVLSTAMGRAYL
CTLSKAEFESLMTSASEERPEEYAAFYDTLCHNVAHYPKRGFALNEGDAGIGVHGVGVYSRIRYLNRPLLFNCALPGSQV
RRGTMEKKIAPLLMEMVRSIEAATGLQQ

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29708; Mature: 29708

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPVEQFIAERRREDPSFGGLLAKGFALLRCFIDEPRPLGNGELAQRLQLPRATVSRIC
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
RTLFELGYLDWDPKLDKYFVSAQVLALGYPYLTGLQVRHVARPLMQALADRIEGAVSMGV
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRLDVTYLQSCTHNEGTPARPGTGAVRSVLSTAMGRAYLCTLSKAEFESLMTSASEERP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCH
EEYAAFYDTLCHNVAHYPKRGFALNEGDAGIGVHGVGVYSRIRYLNRPLLFNCALPGSQV
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHH
RRGTMEKKIAPLLMEMVRSIEAATGLQQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLPVEQFIAERRREDPSFGGLLAKGFALLRCFIDEPRPLGNGELAQRLQLPRATVSRIC
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
RTLFELGYLDWDPKLDKYFVSAQVLALGYPYLTGLQVRHVARPLMQALADRIEGAVSMGV
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRLDVTYLQSCTHNEGTPARPGTGAVRSVLSTAMGRAYLCTLSKAEFESLMTSASEERP
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHCCH
EEYAAFYDTLCHNVAHYPKRGFALNEGDAGIGVHGVGVYSRIRYLNRPLLFNCALPGSQV
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHH
RRGTMEKKIAPLLMEMVRSIEAATGLQQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]