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The map label for this gene is coxM [H]

Identifier: 73537467

GI number: 73537467

Start: 204167

End: 205501

Strand: Direct

Name: coxM [H]

Synonym: Reut_B3632

Alternate gene names: 73537467

Gene position: 204167-205501 (Clockwise)

Preceding gene: 73537466

Following gene: 73537468

Centisome position: 7.49

GC content: 66.37

Gene sequence:

>1335_bases
ATGGCGATGGCCATCGTACTCGTAGTCATCGTCGTCGCTTCGGTGCTCTTTCATTTCATGAGCCCGTGGTGGGCGACCCC
GCTGGCGTCCAACTGGAAGCAGATGGACGACACGCTGACCATTACGCTGGTCATCACGGGCGTCTTCTTCATCGTCATCA
ACCTGTTCCTCGCCTATATGGTCTGGCGCTTTCGCCATGATGCGCCGCGGCATGACGCGCAGCCCGGGCATCGTGCCGAC
TACCATCCCGAGAACAGGAAGCTCGAAATCTGGCTGACCATCGGCACGGCGCTCGGCGTGATGGCGCTGCTCGCGCCGGG
CCTGTTCGTCTATGCGGACTACGTGCGCCCGCCGCGGGAGGCGATGGTGCTCGAAGTGATCGGTCAGCAATGGCAGTGGG
CCTTCCGCTTTCCTGGCAAGAGCGGCCAGCTCGGTACATCCGACCCGCGCTTCATCAGCGGCACCAACCCGCTTGGCCTC
AACCCCGATGATCCGCGCGGCCAGGACAACATTGTCATCAGCGGACCCGAAGTGCACCTGCCGCTGAACCGGCCGGTCAA
GGTGCTGCTGCGCTCGCGCGATGTGCTGCACGACTTCTACGTGCCGCCGTTCCGCGCGCGCATGAACATGGTGCCGGGCA
TGGTGACGTCGTTCTGGTTCACGCCGACGCAGGCCGGGCGCTTCGAAATCCTGTGTGCGCAGCTTTGCGGCGTGGGCCAC
TACAACATGCGCGGCATGGTGGTGGTGGAAGAGCCGGCTGCGTTCGACGCATGGCTGGCGAAGCAGCCGACGTTTGCGCT
GACGCTCGCCAAGGCCGCCGCACCGCCGGCAACTGCGCCGGTGCCGGCGGCTGGTGCCGCTGCCGGCGTGGATCCCGCGC
TGCTGGAGAGGGGCCGTGCGCTGGCACAGAGCAAGGGATGCGCGGGGTGCCACAGCATTGACGGCAACCCCGGCGTGGGT
CCGACGTGGAAAGGCCTGTATGGCAGGACCGAGACGTTTGCCGACGGTAGCACCGCCCCGGTCAACGATGACTTCCTGAA
AGAGGAAATCACCAATCCGCAGGCTCGGCTGGTCAAGGGCTTCGGCCCGGTCATGCCCAAGATAGCGCTGACTGACGATG
AAATTGGCGCCCTGATGGCGTATATCCGTTCGCAGGGCAGTGGAGCGGACACAGGCGCCGCGCCGCCGGAGTCCGCGTCG
GCTGGGGCGCCCACCGGGGCCACCGCCGCGGCCGAGACCAGTTCGCAGGCAGCGTCGTCGGCATCGGGCACCTACACGAC
ATCCAATGCCGCCGTGGTGCCGCCGTCGGCCTCGCCCAAGGCGGCGACGAAGTGA

Upstream 100 bases:

>100_bases
TCCCGATGTCGCCTTGCAGTGACCTGACGGCATGCACTAGTCTTATCTCAACCCTGCGTGACTTCCGCATCCCTCGCCGC
GCGCGAGGAGGAGGGTGGAT

Downstream 100 bases:

>100_bases
GGAGAGACGCATGGCTTACGCCGACGATGCCGACCACCACGCACCGCAGAGCTTCTGGACCCGCTACGTCTGGAGCCAGG
ACCACAAGGTGATCGCCGTG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAMAIVLVVIVVASVLFHFMSPWWATPLASNWKQMDDTLTITLVITGVFFIVINLFLAYMVWRFRHDAPRHDAQPGHRAD
YHPENRKLEIWLTIGTALGVMALLAPGLFVYADYVRPPREAMVLEVIGQQWQWAFRFPGKSGQLGTSDPRFISGTNPLGL
NPDDPRGQDNIVISGPEVHLPLNRPVKVLLRSRDVLHDFYVPPFRARMNMVPGMVTSFWFTPTQAGRFEILCAQLCGVGH
YNMRGMVVVEEPAAFDAWLAKQPTFALTLAKAAAPPATAPVPAAGAAAGVDPALLERGRALAQSKGCAGCHSIDGNPGVG
PTWKGLYGRTETFADGSTAPVNDDFLKEEITNPQARLVKGFGPVMPKIALTDDEIGALMAYIRSQGSGADTGAAPPESAS
AGAPTGATAAAETSSQAASSASGTYTTSNAAVVPPSASPKAATK

Sequences:

>Translated_444_residues
MAMAIVLVVIVVASVLFHFMSPWWATPLASNWKQMDDTLTITLVITGVFFIVINLFLAYMVWRFRHDAPRHDAQPGHRAD
YHPENRKLEIWLTIGTALGVMALLAPGLFVYADYVRPPREAMVLEVIGQQWQWAFRFPGKSGQLGTSDPRFISGTNPLGL
NPDDPRGQDNIVISGPEVHLPLNRPVKVLLRSRDVLHDFYVPPFRARMNMVPGMVTSFWFTPTQAGRFEILCAQLCGVGH
YNMRGMVVVEEPAAFDAWLAKQPTFALTLAKAAAPPATAPVPAAGAAAGVDPALLERGRALAQSKGCAGCHSIDGNPGVG
PTWKGLYGRTETFADGSTAPVNDDFLKEEITNPQARLVKGFGPVMPKIALTDDEIGALMAYIRSQGSGADTGAAPPESAS
AGAPTGATAAAETSSQAASSASGTYTTSNAAVVPPSASPKAATK
>Mature_443_residues
AMAIVLVVIVVASVLFHFMSPWWATPLASNWKQMDDTLTITLVITGVFFIVINLFLAYMVWRFRHDAPRHDAQPGHRADY
HPENRKLEIWLTIGTALGVMALLAPGLFVYADYVRPPREAMVLEVIGQQWQWAFRFPGKSGQLGTSDPRFISGTNPLGLN
PDDPRGQDNIVISGPEVHLPLNRPVKVLLRSRDVLHDFYVPPFRARMNMVPGMVTSFWFTPTQAGRFEILCAQLCGVGHY
NMRGMVVVEEPAAFDAWLAKQPTFALTLAKAAAPPATAPVPAAGAAAGVDPALLERGRALAQSKGCAGCHSIDGNPGVGP
TWKGLYGRTETFADGSTAPVNDDFLKEEITNPQARLVKGFGPVMPKIALTDDEIGALMAYIRSQGSGADTGAAPPESASA
GAPTGATAAAETSSQAASSASGTYTTSNAAVVPPSASPKAATK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=162, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6226540, Length=189, Percent_Identity=25.3968253968254, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 47361; Mature: 47230

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMAIVLVVIVVASVLFHFMSPWWATPLASNWKQMDDTLTITLVITGVFFIVINLFLAYM
CHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHH
VWRFRHDAPRHDAQPGHRADYHPENRKLEIWLTIGTALGVMALLAPGLFVYADYVRPPRE
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCHHEEHHCCCCCHH
AMVLEVIGQQWQWAFRFPGKSGQLGTSDPRFISGTNPLGLNPDDPRGQDNIVISGPEVHL
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCEEEE
PLNRPVKVLLRSRDVLHDFYVPPFRARMNMVPGMVTSFWFTPTQAGRFEILCAQLCGVGH
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC
YNMRGMVVVEEPAAFDAWLAKQPTFALTLAKAAAPPATAPVPAAGAAAGVDPALLERGRA
CCCCEEEEEECCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAQSKGCAGCHSIDGNPGVGPTWKGLYGRTETFADGSTAPVNDDFLKEEITNPQARLVKG
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
FGPVMPKIALTDDEIGALMAYIRSQGSGADTGAAPPESASAGAPTGATAAAETSSQAASS
HCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
ASGTYTTSNAAVVPPSASPKAATK
CCCCEECCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
AMAIVLVVIVVASVLFHFMSPWWATPLASNWKQMDDTLTITLVITGVFFIVINLFLAYM
HHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHH
VWRFRHDAPRHDAQPGHRADYHPENRKLEIWLTIGTALGVMALLAPGLFVYADYVRPPRE
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCHHEEHHCCCCCHH
AMVLEVIGQQWQWAFRFPGKSGQLGTSDPRFISGTNPLGLNPDDPRGQDNIVISGPEVHL
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCEEEECCEEEE
PLNRPVKVLLRSRDVLHDFYVPPFRARMNMVPGMVTSFWFTPTQAGRFEILCAQLCGVGH
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC
YNMRGMVVVEEPAAFDAWLAKQPTFALTLAKAAAPPATAPVPAAGAAAGVDPALLERGRA
CCCCEEEEEECCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
LAQSKGCAGCHSIDGNPGVGPTWKGLYGRTETFADGSTAPVNDDFLKEEITNPQARLVKG
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
FGPVMPKIALTDDEIGALMAYIRSQGSGADTGAAPPESASAGAPTGATAAAETSSQAASS
HCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
ASGTYTTSNAAVVPPSASPKAATK
CCCCEECCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]