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The map label for this gene is czcB [H]

Identifier: 73537337

GI number: 73537337

Start: 39625

End: 40833

Strand: Direct

Name: czcB [H]

Synonym: Reut_B3502

Alternate gene names: 73537337

Gene position: 39625-40833 (Clockwise)

Preceding gene: 73537336

Following gene: 73537338

Centisome position: 1.45

GC content: 67.99

Gene sequence:

>1209_bases
ATGCGCCGCGTCCCTAATCTGCTGTCCGAAGTGTTTCGAGTTTCTCCCGCCGGCCTGCCTGCGCGCGTGGCCGCCTTGTC
CCTGTGCGCGCTGGCGCTTGCCGCTTGCGGCAAGGAAGAAGCGCCCAAGGCCGATGACGAGCCCAAGGTCACGGGCGAAA
CCGTCCAGTTCCCGGCGAGCGTGAAGACTCTGCCCGGCATCGCGGGCGAAGCCGCCCGCACCGGTGGCCAGCGCATGCTG
AACCTGCCGGGCCGCCTGGGGTGGAACGAGGACAAGACCGTGCGCGTCTCCACGCCGTTTGCCGGCCGCGTGACGGAAAT
CCTGGTTCAGCCGGGCGCTACGGTAAAAGCCGGCCAGCCGCTGGCAAACCTGACCTCGTCGGACTTTGGCGTGGCCCAGG
CCGATGCGCGCAAAGCTGCCGCCGACAATTCGGTCGCAGCCAAGGCGCTGGCGCGCCAACGCGAGCTGTACGCAGCAGGC
GTGATTGCCCAGAAGGACCTGGAGCAGTCCCAGGCCGACGCCGCACGCACGGCGGCCGACCTGGCGCGCACGCAGGCGGC
GCTGCGGCAGTACGGCGGCGCGGCTGGCGACGGTGCCAACCGCTTCTCGCTGCGCAGCCCCATCGACGGACTGGTGGTGG
AGCGCAACATCAACCCCGGCATGGAACTGCGCCCTGACCAGCCGCCCACCGCGCCGCTGTTCCTGGTAACCGATCCGACC
ACGCTGTGGGCACAGGTCGATGCCGGCGAGGCCGACCTTGGCCTGTTCAAGCCCGGCGTGACCGTGCAGCTCATCTCTGC
CGCCTATCCGGGCGAGACCTTCCCTGGCACCGTGGTGAAGATCGCCGATTATGTCGACCCGACTTCGCGCAGCATCAAGG
TGCGCCTTGCCGTGCCCAATGCCGACCGCCGGCTCAAGGCCGAGATGTTCGTCACGGCCCGGCTGCAGGCGGCGTCGTTC
CAGGGTATTGCCGTGCCGTCCAAGGCAGTGTTCCTGGCCGACAACCGCAACTATGTATTCGTGCGCACCGCGCCCAACAC
CTTCGTGCGCCGTCCGGTGAAGCTCGGCGTGTCGTTGCCTGGTGTCAGCGAGGTGGTTGACGGCATCAAGGATGGCGAAA
CCGTGGTGACCGACGGCAATCTCTACCTGCAGGACATCCTGCGCGACGCCACCGCCGTCAACAACGCGCGCGCTGCGGCC
AAGCAATAA

Upstream 100 bases:

>100_bases
GCCCAGGGCGACTACGCCAAGGCCCTGTCGGCTTACCGCACGGCGTTGCAGTCCACCACCACTCCCGTCAGCTCCATCCC
GAATTCCCAGGTCCGTACCG

Downstream 100 bases:

>100_bases
GGACGGCCGCCAGATGATTTCGCGTATCGTCAATTTTGCCCTGCACCAGAAGCTGTTTGTCTGGCTGGGCCTGCTGATCT
TTGTGGGCGGCGGCCTGGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MRRVPNLLSEVFRVSPAGLPARVAALSLCALALAACGKEEAPKADDEPKVTGETVQFPASVKTLPGIAGEAARTGGQRML
NLPGRLGWNEDKTVRVSTPFAGRVTEILVQPGATVKAGQPLANLTSSDFGVAQADARKAAADNSVAAKALARQRELYAAG
VIAQKDLEQSQADAARTAADLARTQAALRQYGGAAGDGANRFSLRSPIDGLVVERNINPGMELRPDQPPTAPLFLVTDPT
TLWAQVDAGEADLGLFKPGVTVQLISAAYPGETFPGTVVKIADYVDPTSRSIKVRLAVPNADRRLKAEMFVTARLQAASF
QGIAVPSKAVFLADNRNYVFVRTAPNTFVRRPVKLGVSLPGVSEVVDGIKDGETVVTDGNLYLQDILRDATAVNNARAAA
KQ

Sequences:

>Translated_402_residues
MRRVPNLLSEVFRVSPAGLPARVAALSLCALALAACGKEEAPKADDEPKVTGETVQFPASVKTLPGIAGEAARTGGQRML
NLPGRLGWNEDKTVRVSTPFAGRVTEILVQPGATVKAGQPLANLTSSDFGVAQADARKAAADNSVAAKALARQRELYAAG
VIAQKDLEQSQADAARTAADLARTQAALRQYGGAAGDGANRFSLRSPIDGLVVERNINPGMELRPDQPPTAPLFLVTDPT
TLWAQVDAGEADLGLFKPGVTVQLISAAYPGETFPGTVVKIADYVDPTSRSIKVRLAVPNADRRLKAEMFVTARLQAASF
QGIAVPSKAVFLADNRNYVFVRTAPNTFVRRPVKLGVSLPGVSEVVDGIKDGETVVTDGNLYLQDILRDATAVNNARAAA
KQ
>Mature_402_residues
MRRVPNLLSEVFRVSPAGLPARVAALSLCALALAACGKEEAPKADDEPKVTGETVQFPASVKTLPGIAGEAARTGGQRML
NLPGRLGWNEDKTVRVSTPFAGRVTEILVQPGATVKAGQPLANLTSSDFGVAQADARKAAADNSVAAKALARQRELYAAG
VIAQKDLEQSQADAARTAADLARTQAALRQYGGAAGDGANRFSLRSPIDGLVVERNINPGMELRPDQPPTAPLFLVTDPT
TLWAQVDAGEADLGLFKPGVTVQLISAAYPGETFPGTVVKIADYVDPTSRSIKVRLAVPNADRRLKAEMFVTARLQAASF
QGIAVPSKAVFLADNRNYVFVRTAPNTFVRRPVKLGVSLPGVSEVVDGIKDGETVVTDGNLYLQDILRDATAVNNARAAA
KQ

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=299, Percent_Identity=25.0836120401338, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786787, Length=306, Percent_Identity=26.1437908496732, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42357; Mature: 42357

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVPNLLSEVFRVSPAGLPARVAALSLCALALAACGKEEAPKADDEPKVTGETVQFPAS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
VKTLPGIAGEAARTGGQRMLNLPGRLGWNEDKTVRVSTPFAGRVTEILVQPGATVKAGQP
HHHCCCCCCHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCHHHHEECCCCCEECCCC
LANLTSSDFGVAQADARKAAADNSVAAKALARQRELYAAGVIAQKDLEQSQADAARTAAD
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARTQAALRQYGGAAGDGANRFSLRSPIDGLVVERNINPGMELRPDQPPTAPLFLVTDPT
HHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCC
TLWAQVDAGEADLGLFKPGVTVQLISAAYPGETFPGTVVKIADYVDPTSRSIKVRLAVPN
EEEEEECCCCCCCCEECCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCC
ADRRLKAEMFVTARLQAASFQGIAVPSKAVFLADNRNYVFVRTAPNTFVRRPVKLGVSLP
CCCCEEEEEEEEEEEHHCCCCCEECCCCEEEEECCCCEEEEEECCCHHHCCHHHCCCCCC
GVSEVVDGIKDGETVVTDGNLYLQDILRDATAVNNARAAAKQ
CHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MRRVPNLLSEVFRVSPAGLPARVAALSLCALALAACGKEEAPKADDEPKVTGETVQFPAS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
VKTLPGIAGEAARTGGQRMLNLPGRLGWNEDKTVRVSTPFAGRVTEILVQPGATVKAGQP
HHHCCCCCCHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCHHHHEECCCCCEECCCC
LANLTSSDFGVAQADARKAAADNSVAAKALARQRELYAAGVIAQKDLEQSQADAARTAAD
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARTQAALRQYGGAAGDGANRFSLRSPIDGLVVERNINPGMELRPDQPPTAPLFLVTDPT
HHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCC
TLWAQVDAGEADLGLFKPGVTVQLISAAYPGETFPGTVVKIADYVDPTSRSIKVRLAVPN
EEEEEECCCCCCCCEECCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEEECCC
ADRRLKAEMFVTARLQAASFQGIAVPSKAVFLADNRNYVFVRTAPNTFVRRPVKLGVSLP
CCCCEEEEEEEEEEEHHCCCCCEECCCCEEEEECCCCEEEEEECCCHHHCCHHHCCCCCC
GVSEVVDGIKDGETVVTDGNLYLQDILRDATAVNNARAAAKQ
CHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]