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The map label for this gene is ubiE [H]

Identifier: 73537330

GI number: 73537330

Start: 32211

End: 33038

Strand: Direct

Name: ubiE [H]

Synonym: Reut_B3495

Alternate gene names: 73537330

Gene position: 32211-33038 (Clockwise)

Preceding gene: 73537329

Following gene: 73537331

Centisome position: 1.18

GC content: 67.87

Gene sequence:

>828_bases
ATGGATCACACGGGGGAGAGTTTCCGTGATTTCGAGCTGGCCGGCTGGGAAGATCCCGGCGTCGTCAGCCGCTACCACGA
GCAGCTCACGGTCGTCACGACGCAATCAGTCGATGCCTTGCTCGACAGCGCGCACGTCGGCAGCGGCCAGCGCGTGCTCG
ATGTGGCCAGCGGCGCTGGCTATGTTGCCGCTGCTGCGGCCCGGCGGGGCGCGGACACGGTCGGCATCGATTTCTCTGCC
ACGCAGGTGGAGCTGGCACGCAAGACCCATCCAGGCCTGCACTTCGAACAGGCCGATGCGCAGGACCTGCCGTTCGATGC
GGACAGCTTCGACGCCGTCGTCAATGGTTTCGGCATGTGCCACCTGACCGATCCGGACCAGGCGCTGCGCGAGGCATTCC
GCGTACTGCGTCCCGGCGGGCGCATCGGCTTCACGGTGTGGGACGCGCCCGAACGCGCGATCGGCTTCGGCGCCGTTTAC
GCGGCGATCCGGGCCTATGGGTCGATGGATGTCGGCCTGCCGGCCGGCCCCAACTTCTTCCAGTTCAGCGATCCGCCGCA
ATGCATCAGCGCCTTGCAGAACGCCGGCTTCACTGGCGCAGCCTGCAGGCAGGTGCCGCAGCTGTGGCGCTTCTCGGCGC
CCGACCAGCTCTTCGACGCGCTGGCACAGGGCACCGTGCGTGCCGCGGCCACCATCCGTGCGCAAAGTCCCAAGGCGCGC
GATGAGATCCGGGCCGTGCTGCGCGGCACGGTTGCCTCGTACATGAAGGGCAATGACTTTGTCGTGCCGATGCCGGCGGT
GCTGGCATGGGCGCAGAAGCCCGCGTAA

Upstream 100 bases:

>100_bases
ATACTTCGCCTGTCTGGCGACCGGCGTGCCGGGGGGGCGCGCGCGCCAGACAGGGCGGCAGGCCAGCGCCCCGCAGCGAA
TTTCGCCAAGGGAGGGTGCA

Downstream 100 bases:

>100_bases
CCCACGTAACCCGCACCGCAGATCCGCATTCTTGCGCCGTCGCCTCTGCCGGCTAACCGGCAGGGGGGCGGGACGTGCCG
CCAGGCCGGGGGCGCCGAAT

Product: UbiE/COQ5 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MDHTGESFRDFELAGWEDPGVVSRYHEQLTVVTTQSVDALLDSAHVGSGQRVLDVASGAGYVAAAAARRGADTVGIDFSA
TQVELARKTHPGLHFEQADAQDLPFDADSFDAVVNGFGMCHLTDPDQALREAFRVLRPGGRIGFTVWDAPERAIGFGAVY
AAIRAYGSMDVGLPAGPNFFQFSDPPQCISALQNAGFTGAACRQVPQLWRFSAPDQLFDALAQGTVRAAATIRAQSPKAR
DEIRAVLRGTVASYMKGNDFVVPMPAVLAWAQKPA

Sequences:

>Translated_275_residues
MDHTGESFRDFELAGWEDPGVVSRYHEQLTVVTTQSVDALLDSAHVGSGQRVLDVASGAGYVAAAAARRGADTVGIDFSA
TQVELARKTHPGLHFEQADAQDLPFDADSFDAVVNGFGMCHLTDPDQALREAFRVLRPGGRIGFTVWDAPERAIGFGAVY
AAIRAYGSMDVGLPAGPNFFQFSDPPQCISALQNAGFTGAACRQVPQLWRFSAPDQLFDALAQGTVRAAATIRAQSPKAR
DEIRAVLRGTVASYMKGNDFVVPMPAVLAWAQKPA
>Mature_275_residues
MDHTGESFRDFELAGWEDPGVVSRYHEQLTVVTTQSVDALLDSAHVGSGQRVLDVASGAGYVAAAAARRGADTVGIDFSA
TQVELARKTHPGLHFEQADAQDLPFDADSFDAVVNGFGMCHLTDPDQALREAFRVLRPGGRIGFTVWDAPERAIGFGAVY
AAIRAYGSMDVGLPAGPNFFQFSDPPQCISALQNAGFTGAACRQVPQLWRFSAPDQLFDALAQGTVRAAATIRAQSPKAR
DEIRAVLRGTVASYMKGNDFVVPMPAVLAWAQKPA

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=119, Percent_Identity=33.6134453781513, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29399; Mature: 29399

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHTGESFRDFELAGWEDPGVVSRYHEQLTVVTTQSVDALLDSAHVGSGQRVLDVASGAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCC
YVAAAAARRGADTVGIDFSATQVELARKTHPGLHFEQADAQDLPFDADSFDAVVNGFGMC
HHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEE
HLTDPDQALREAFRVLRPGGRIGFTVWDAPERAIGFGAVYAAIRAYGSMDVGLPAGPNFF
EECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QFSDPPQCISALQNAGFTGAACRQVPQLWRFSAPDQLFDALAQGTVRAAATIRAQSPKAR
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHEEECCCCCHH
DEIRAVLRGTVASYMKGNDFVVPMPAVLAWAQKPA
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure
MDHTGESFRDFELAGWEDPGVVSRYHEQLTVVTTQSVDALLDSAHVGSGQRVLDVASGAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCC
YVAAAAARRGADTVGIDFSATQVELARKTHPGLHFEQADAQDLPFDADSFDAVVNGFGMC
HHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEE
HLTDPDQALREAFRVLRPGGRIGFTVWDAPERAIGFGAVYAAIRAYGSMDVGLPAGPNFF
EECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QFSDPPQCISALQNAGFTGAACRQVPQLWRFSAPDQLFDALAQGTVRAAATIRAQSPKAR
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHEEECCCCCHH
DEIRAVLRGTVASYMKGNDFVVPMPAVLAWAQKPA
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]