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The map label for this gene is pyrH [H]

Identifier: 71893887

GI number: 71893887

Start: 693854

End: 694564

Strand: Reverse

Name: pyrH [H]

Synonym: MHJ_0536

Alternate gene names: 71893887

Gene position: 694564-693854 (Counterclockwise)

Preceding gene: 71893890

Following gene: 71893886

Centisome position: 77.4

GC content: 33.76

Gene sequence:

>711_bases
ATGGACTCAACTATTCTTATTAAACTTTCAGGCGAAAGTCTTGCAAATAAACAAAAATCTCTGGCAATCGATTATGAACT
TGTAAGACAAATCGGTTCTCAACTCAAAGAAATACAGAATTTAGGGCATAAAATTTTAATTGTTATCGGCGGCGGAAATT
TTTGACGCGGTACTTCCGCGGCAAAAAATGGTATAAACAGGAACACCGCTGATTATATCGGGATGCTTGGAACTGTTATG
AACGGGCTTGCCCTTGATTCAGTTTTCCGCGATTTGGGAATTAAAACTCGAGTTTTATCCTCGATGAGTTTAGACCCGCG
AATTTGTGAGTATTTTGTCAGGGAAAAAGCGATGAAATATTTAGAAGATAACAATGTTTTAATTTTTGTTGGCGGGACCG
GCCGCCCATTTTTTACAACTGATAGTGCTGCAACACTTTTTGCATCCGAAATGGGTGCAAATATTATTTTAGTGGGCAAA
AATAATGTCAATGGCATTTTTGACTCTGATCCAAAAATTAATCCAAATGCGCTAAGATATGATAAAATTACTTATAATCA
AGTTATTGAAAAAAATTTAAAGGTAATGGACTCAACAGCTTTTTCAATGGCTCGTGATAATAAAATTAAATTACTAATTT
TTGATATTAAAGAAAAAAATAGCATTTCTAAATTAATCAAAAGACAAATTAAACACACGGAGGTTTATTAG

Upstream 100 bases:

>100_bases
CAAAAAAAATAAAATCTGCAACTTTTTCCTAAAATTTTCCTTTTTTTAATACATTTTTTTTCAAAAATAAAGTATAATAA
AAGAAACTTTTAAGGCTAAT

Downstream 100 bases:

>100_bases
ATAATGAAGAACGAAATTGAATTTAGTTTTTATAAAAACATCTTGATTGAAAAAGCTCAAGATGTTTTTTCCTATCTTGA
AAAAAGTTTTCAGAAAGTAA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNFWRGTSAAKNGINRNTADYIGMLGTVM
NGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYLEDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGK
NNVNGIFDSDPKINPNALRYDKITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY

Sequences:

>Translated_236_residues
MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNF*RGTSAAKNGINRNTADYIGMLGTVM
NGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYLEDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGK
NNVNGIFDSDPKINPNALRYDKITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY
>Mature_236_residues
MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNF*RGTSAAKNGINRNTADYIGMLGTVM
NGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYLEDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGK
NNVNGIFDSDPKINPNALRYDKITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=222, Percent_Identity=40.0900900900901, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26115; Mature: 26115

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNFRGTSAA
CCCEEEEEECCCHHHCHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
KNGINRNTADYIGMLGTVMNGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGKNNVNGIFDSDPKINPNALRYD
CCCCEEEEECCCCCCEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEC
KITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNFRGTSAA
CCCEEEEEECCCHHHCHHHHEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
KNGINRNTADYIGMLGTVMNGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGKNNVNGIFDSDPKINPNALRYD
CCCCEEEEECCCCCCEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEC
KITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA