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The map label for this gene is map [H]

Identifier: 71893525

GI number: 71893525

Start: 200501

End: 201253

Strand: Reverse

Name: map [H]

Synonym: MHJ_0169

Alternate gene names: 71893525

Gene position: 201253-200501 (Counterclockwise)

Preceding gene: 71893526

Following gene: 71893524

Centisome position: 22.43

GC content: 33.33

Gene sequence:

>753_bases
ATGGCTATAATTAAAAATGAATTTGAAATAAGCCAGTTGAAAATTGCTGGCAAAATCTTGGCAGAAGTTAAGGCAAAAAT
TTATGACTTTGTAAGACCAGGAATCTCTTTAAAAGAACTGGATGCCATAGCTTTTGAAGAGATTAAAAGCCGAAATGCAA
AACCAGCTTTTCTAAATTATCACGGTTTTCCGGCAACAATTTGTGCAAGTGTTAATGAAATTCTTATCCATGGAATCCCC
AGTGAATATGTCATTAAAGAAAATGATCTTGTTTCAATCGATTTAGGACTTTCTTATAATGGTTTTTTTGTAGATAGTGC
ATTTACAAAATCACTTGGACCAGATCAAGAAAATCAAAAATTAATTAACTGCGCAAAAGAAGCATTTTTTGCCGGTTTTA
AAGCGATAAAACCTGGAGCAAAAACAGGTGATATCGGTTTTGCAATTAACAACGTAATAAAATCCTATGGATTTTTCACT
CCCTATGAATTTTCTGGTCATGGGATAGGCAAAAAATTACACGAAAATCCAAACATTTATAATTTCGGCATCCCCAAAAA
AGGGATAGAGTTAGTTGATAATATGGTTATCTGCATTGAACCAATGATTCTACAAACCTCGCCGCATATTAAAATTTTAA
AGGATGGATGGTCGGTAAAAGCAAAAGATGGCAGAAAAACCTCCCATTATGAAGAGACAATTTTAATTAAGGATGGTAGA
GGGATAATTCTTACAGAAATGGCTCAAAACTAG

Upstream 100 bases:

>100_bases
ATTCAGTGATTCCAATTGTTGAATTTTTCAAAAAAAGTGGTATAATATATTATCTAGATGCCGAGCAAACCCTTGAAGAA
ACAGTTATAGAAATTGAAAA

Downstream 100 bases:

>100_bases
ATGGCAAATTTACCAAAAGAACAAAAACTATTATTTCAGGGAAAAGTCACCCACGTTTTTAATGCCCAGGAATATGAGGT
AACTCTCGAAAATGGGATTA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAIIKNEFEISQLKIAGKILAEVKAKIYDFVRPGISLKELDAIAFEEIKSRNAKPAFLNYHGFPATICASVNEILIHGIP
SEYVIKENDLVSIDLGLSYNGFFVDSAFTKSLGPDQENQKLINCAKEAFFAGFKAIKPGAKTGDIGFAINNVIKSYGFFT
PYEFSGHGIGKKLHENPNIYNFGIPKKGIELVDNMVICIEPMILQTSPHIKILKDGWSVKAKDGRKTSHYEETILIKDGR
GIILTEMAQN

Sequences:

>Translated_250_residues
MAIIKNEFEISQLKIAGKILAEVKAKIYDFVRPGISLKELDAIAFEEIKSRNAKPAFLNYHGFPATICASVNEILIHGIP
SEYVIKENDLVSIDLGLSYNGFFVDSAFTKSLGPDQENQKLINCAKEAFFAGFKAIKPGAKTGDIGFAINNVIKSYGFFT
PYEFSGHGIGKKLHENPNIYNFGIPKKGIELVDNMVICIEPMILQTSPHIKILKDGWSVKAKDGRKTSHYEETILIKDGR
GIILTEMAQN
>Mature_249_residues
AIIKNEFEISQLKIAGKILAEVKAKIYDFVRPGISLKELDAIAFEEIKSRNAKPAFLNYHGFPATICASVNEILIHGIPS
EYVIKENDLVSIDLGLSYNGFFVDSAFTKSLGPDQENQKLINCAKEAFFAGFKAIKPGAKTGDIGFAINNVIKSYGFFTP
YEFSGHGIGKKLHENPNIYNFGIPKKGIELVDNMVICIEPMILQTSPHIKILKDGWSVKAKDGRKTSHYEETILIKDGRG
IILTEMAQN

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=32.3886639676113, Blast_Score=147, Evalue=7e-36,
Organism=Homo sapiens, GI164420681, Length=239, Percent_Identity=30.5439330543933, Blast_Score=141, Evalue=4e-34,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=35.7429718875502, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788728, Length=209, Percent_Identity=25.3588516746411, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71996291, Length=246, Percent_Identity=30.8943089430894, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323273, Length=239, Percent_Identity=31.3807531380753, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21355531, Length=248, Percent_Identity=29.4354838709677, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=30.0813008130081, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27715; Mature: 27584

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIKNEFEISQLKIAGKILAEVKAKIYDFVRPGISLKELDAIAFEEIKSRNAKPAFLNY
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
HGFPATICASVNEILIHGIPSEYVIKENDLVSIDLGLSYNGFFVDSAFTKSLGPDQENQK
CCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCCCEEECCHHHHCCCCCCHHHH
LINCAKEAFFAGFKAIKPGAKTGDIGFAINNVIKSYGFFTPYEFSGHGIGKKLHENPNIY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCEE
NFGIPKKGIELVDNMVICIEPMILQTSPHIKILKDGWSVKAKDGRKTSHYEETILIKDGR
ECCCCHHHHHHHCCEEEEECCEEECCCCCEEEEECCCEEEECCCCCCCCCCEEEEEECCC
GIILTEMAQN
CEEEEECCCC
>Mature Secondary Structure 
AIIKNEFEISQLKIAGKILAEVKAKIYDFVRPGISLKELDAIAFEEIKSRNAKPAFLNY
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
HGFPATICASVNEILIHGIPSEYVIKENDLVSIDLGLSYNGFFVDSAFTKSLGPDQENQK
CCCHHHHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCCCEEECCHHHHCCCCCCHHHH
LINCAKEAFFAGFKAIKPGAKTGDIGFAINNVIKSYGFFTPYEFSGHGIGKKLHENPNIY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCEE
NFGIPKKGIELVDNMVICIEPMILQTSPHIKILKDGWSVKAKDGRKTSHYEETILIKDGR
ECCCCHHHHHHHCCEEEEECCEEECCCCCEEEEECCCEEEECCCCCCCCCCEEEEEECCC
GIILTEMAQN
CEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476192 [H]