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The map label for this gene is ilvE [H]

Identifier: 71892356

GI number: 71892356

Start: 734104

End: 735024

Strand: Reverse

Name: ilvE [H]

Synonym: BPEN_612

Alternate gene names: 71892356

Gene position: 735024-734104 (Counterclockwise)

Preceding gene: 71892357

Following gene: 71892355

Centisome position: 92.85

GC content: 35.4

Gene sequence:

>921_bases
ATGAATATATCAAACTTTATTTGGTTTAATGGGGAAATCGTACCATGGCAAGAAGCTAAAGTACATGTAATGTCTCATGC
TTTGCACTATGGATCATCAGTATTTGAAGGTATGAGATGTTATAATTCACATAAAGGTCCCGTTATATTTCGTCATCGTG
AACACATACAAAGATTGTATAATTCCGCAAAAATTTATCGTATGCCTATTTTTTGGAGTATTGATGATTTAATGGAAGCT
TGTAGAATTATTATTCGAAAGAATAATTTAATCAATGCATATATCCGTCCTCTCGTATTTATTGGAAATGTAGGTATGCA
AATTAATCCGACTCCCGGATACGCTACTGACGTTGCTATAGCAGCTTTTTCTTGGCTGCCTTATCTGGGAGAAAATTCTT
TGAAACAAGGGATTGATGTTATGGTATCTTCCTGGAATAGAGTTCCAGCAAATACCCTTCCAAGCACAGCGAAAGCTGGC
GGAAATTATCTATCATCTATGTTAATTAGCAATGAAGCTCACCGAAATGGTTATCAAGAAGGAATAGGTTTAGATATATA
TGGTTATATTTCAGAAGGTGCCGGTGAAAATTTATTTGAAGTTAAAAGTAATATTCTTTTAACACCACCATGTGCTTCTT
CTATTTTACCTGGGGTCACACGTGATACTATTATTAAGTTAGCAGTAAATATTGGTTTAGAAGTACAAGAACAAGTATTA
CCCCGTGAATCTCTATACATAGCTGATGAAATATTTATGTCTGGTACTGCTGCCGAAATAACCCCAGTACGTACTGTAGA
TGGAATTAAGGTAGGTACCGGTACGCGCGGACCCATCACTAAAAAATTACAGCACTTATTTTTTAACTTATTTACTGGAA
TCACTGAAGATCAATGGAATTGGTTAGATCCAGTGCATTAG

Upstream 100 bases:

>100_bases
AAATAAATTAATGGATATACATTATATTAAAATTGAATAAATTAAAAAATAATAATTAAATTCGTACTTTCTTCGACTAT
ATTACCGAGGAAGATATCAG

Downstream 100 bases:

>100_bases
CAATACTACATTGATGCAATGTTAATTCTTAAGATAATCAATATTCAATAATATAGAATACTGGAGTTAAATATGCCTAA
ATATCGCTCTATTACTACTA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNISNFIWFNGEIVPWQEAKVHVMSHALHYGSSVFEGMRCYNSHKGPVIFRHREHIQRLYNSAKIYRMPIFWSIDDLMEA
CRIIIRKNNLINAYIRPLVFIGNVGMQINPTPGYATDVAIAAFSWLPYLGENSLKQGIDVMVSSWNRVPANTLPSTAKAG
GNYLSSMLISNEAHRNGYQEGIGLDIYGYISEGAGENLFEVKSNILLTPPCASSILPGVTRDTIIKLAVNIGLEVQEQVL
PRESLYIADEIFMSGTAAEITPVRTVDGIKVGTGTRGPITKKLQHLFFNLFTGITEDQWNWLDPVH

Sequences:

>Translated_306_residues
MNISNFIWFNGEIVPWQEAKVHVMSHALHYGSSVFEGMRCYNSHKGPVIFRHREHIQRLYNSAKIYRMPIFWSIDDLMEA
CRIIIRKNNLINAYIRPLVFIGNVGMQINPTPGYATDVAIAAFSWLPYLGENSLKQGIDVMVSSWNRVPANTLPSTAKAG
GNYLSSMLISNEAHRNGYQEGIGLDIYGYISEGAGENLFEVKSNILLTPPCASSILPGVTRDTIIKLAVNIGLEVQEQVL
PRESLYIADEIFMSGTAAEITPVRTVDGIKVGTGTRGPITKKLQHLFFNLFTGITEDQWNWLDPVH
>Mature_306_residues
MNISNFIWFNGEIVPWQEAKVHVMSHALHYGSSVFEGMRCYNSHKGPVIFRHREHIQRLYNSAKIYRMPIFWSIDDLMEA
CRIIIRKNNLINAYIRPLVFIGNVGMQINPTPGYATDVAIAAFSWLPYLGENSLKQGIDVMVSSWNRVPANTLPSTAKAG
GNYLSSMLISNEAHRNGYQEGIGLDIYGYISEGAGENLFEVKSNILLTPPCASSILPGVTRDTIIKLAVNIGLEVQEQVL
PRESLYIADEIFMSGTAAEITPVRTVDGIKVGTGTRGPITKKLQHLFFNLFTGITEDQWNWLDPVH

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=303, Percent_Identity=70.957095709571, Blast_Score=475, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17565728, Length=283, Percent_Identity=28.6219081272085, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641779, Length=290, Percent_Identity=27.2413793103448, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34258; Mature: 34258

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISNFIWFNGEIVPWQEAKVHVMSHALHYGSSVFEGMRCYNSHKGPVIFRHREHIQRLY
CCCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
NSAKIYRMPIFWSIDDLMEACRIIIRKNNLINAYIRPLVFIGNVGMQINPTPGYATDVAI
CCCEEEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEEECCCCCHHHHHH
AAFSWLPYLGENSLKQGIDVMVSSWNRVPANTLPSTAKAGGNYLSSMLISNEAHRNGYQE
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCHHC
GIGLDIYGYISEGAGENLFEVKSNILLTPPCASSILPGVTRDTIIKLAVNIGLEVQEQVL
CCCEEEEEEECCCCCCCHHHHCCCEEECCCCHHHHCCCCCHHHHHHHHHHCCCHHHHHHC
PRESLYIADEIFMSGTAAEITPVRTVDGIKVGTGTRGPITKKLQHLFFNLFTGITEDQWN
CCHHHEEHHHHHHCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
WLDPVH
CCCCCC
>Mature Secondary Structure
MNISNFIWFNGEIVPWQEAKVHVMSHALHYGSSVFEGMRCYNSHKGPVIFRHREHIQRLY
CCCCCEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
NSAKIYRMPIFWSIDDLMEACRIIIRKNNLINAYIRPLVFIGNVGMQINPTPGYATDVAI
CCCEEEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEEECCCCCHHHHHH
AAFSWLPYLGENSLKQGIDVMVSSWNRVPANTLPSTAKAGGNYLSSMLISNEAHRNGYQE
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCHHC
GIGLDIYGYISEGAGENLFEVKSNILLTPPCASSILPGVTRDTIIKLAVNIGLEVQEQVL
CCCEEEEEEECCCCCCCHHHHCCCEEECCCCHHHHCCCCCHHHHHHHHHHCCCHHHHHHC
PRESLYIADEIFMSGTAAEITPVRTVDGIKVGTGTRGPITKKLQHLFFNLFTGITEDQWN
CCHHHEEHHHHHHCCCCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
WLDPVH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]