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The map label for this gene is ndk [H]

Identifier: 71892306

GI number: 71892306

Start: 662040

End: 662450

Strand: Reverse

Name: ndk [H]

Synonym: BPEN_553

Alternate gene names: 71892306

Gene position: 662450-662040 (Counterclockwise)

Preceding gene: 71892307

Following gene: 71892305

Centisome position: 83.68

GC content: 31.87

Gene sequence:

>411_bases
ATGGTTTGCAAAGAAAATACGCTGTCAATCATAAAACCAGATGCTGTTGCTAAAAACATAATCGGATCTATAATTAGTAG
ATTCGAGACTGCTGGTCTTATTATTGTGGGAGCTAAAATATTGCAATTAACATATATACAAGCTTCCGAGTTTTATTTTG
AACATCAAAAAAAATATTTTTTTGACAGTTTAGTAAATTTTATGATTTCTGGACCAGTATTTGTACAAATACTGGAAGGT
AATAATTCGATACAACGCAATAGAGAAATTATGGGAGCCACTGATCCAGCGAATGCGTTAGCAGGCACCATTAGATCTGA
TTATGGTTATAATTATACTAAAAATGCCATCCATGGATCGGATTCTAAAAAATCTGCTATACGTGAAATTTCCTATTTCT
TTGATACATAA

Upstream 100 bases:

>100_bases
AAAAATATTAAATAATATAAACAATATTATCTACAATAATTATTGTTTTTATATTTATTTTCTATACAATAATATTAATA
AATGATTAATAGGAGTTTTT

Downstream 100 bases:

>100_bases
AAACATGCAGATACATTATCTTTTATAAAAGTAATCATTTTAGCTACACAAAAAAATGATTTTTGATTAGTGAATTAGTT
TATCAAAAAAATAGTGTTAA

Product: 3'-phosphodiesterase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASEFYFEHQKKYFFDSLVNFMISGPVFVQILEG
NNSIQRNREIMGATDPANALAGTIRSDYGYNYTKNAIHGSDSKKSAIREISYFFDT

Sequences:

>Translated_136_residues
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASEFYFEHQKKYFFDSLVNFMISGPVFVQILEG
NNSIQRNREIMGATDPANALAGTIRSDYGYNYTKNAIHGSDSKKSAIREISYFFDT
>Mature_136_residues
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASEFYFEHQKKYFFDSLVNFMISGPVFVQILEG
NNSIQRNREIMGATDPANALAGTIRSDYGYNYTKNAIHGSDSKKSAIREISYFFDT

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI4826862, Length=133, Percent_Identity=39.8496240601504, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI37693993, Length=130, Percent_Identity=40.7692307692308, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI66392203, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI38045913, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392227, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392205, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4505409, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI66392192, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4557797, Length=130, Percent_Identity=41.5384615384615, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI37574614, Length=139, Percent_Identity=34.5323741007194, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI7019465, Length=139, Percent_Identity=34.5323741007194, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI5031951, Length=132, Percent_Identity=37.8787878787879, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4505413, Length=137, Percent_Identity=38.6861313868613, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=34.8148148148148, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788866, Length=130, Percent_Identity=62.3076923076923, Blast_Score=174, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17506807, Length=134, Percent_Identity=37.3134328358209, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6322783, Length=130, Percent_Identity=40, Blast_Score=113, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45549037, Length=132, Percent_Identity=40.1515151515151, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI18860097, Length=133, Percent_Identity=36.8421052631579, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15216; Mature: 15216

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASEFYFEHQKKYF
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
FDSLVNFMISGPVFVQILEGNNSIQRNREIMGATDPANALAGTIRSDYGYNYTKNAIHGS
HHHHHHHHHCCCEEEEEECCCCCHHHCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DSKKSAIREISYFFDT
CHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVCKENTLSIIKPDAVAKNIIGSIISRFETAGLIIVGAKILQLTYIQASEFYFEHQKKYF
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
FDSLVNFMISGPVFVQILEGNNSIQRNREIMGATDPANALAGTIRSDYGYNYTKNAIHGS
HHHHHHHHHCCCEEEEEECCCCCHHHCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
DSKKSAIREISYFFDT
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA