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The map label for this gene is hisS

Identifier: 71892303

GI number: 71892303

Start: 658032

End: 659348

Strand: Reverse

Name: hisS

Synonym: BPEN_550

Alternate gene names: 71892303

Gene position: 659348-658032 (Counterclockwise)

Preceding gene: 71892304

Following gene: 71892302

Centisome position: 83.29

GC content: 31.21

Gene sequence:

>1317_bases
ATGCTTAAATATGATAAAAATATCCAATCTGTCCGCGGTATGCATGATTATTTGCCGAAAGATACGATTCTATGGCAATA
CATAGAAAATATACTTATAACTATATTAGACAGTTACGGATACAAGGAGATTAGATTTCCTATTATTGAAGACACAAATT
TATTCAAACGCTCAATCGGAGAAGTGACAGATGTAATAGAAAAAGAAATGTATAATTTTACTGATCGCAACGGTAATAAT
TTAACGTTACGTCCAGAAGGAACATCTGGATGCGTTCGCGCGGGTATTAAGCATGGGCTGTTTTATCACCAAGAACAACG
TCTGTGGTATCTCGGTCCGATGTTTCGCTATGAACGTCCCCAAAAAGGACGTTATAGGCAATTTCATCAATTTAGTGCTG
AAGCTTTTGGTCAAATCGGACCCGACATAGATGCTGAGTTAATTTTAATTACTGCTCGTTGTTGGAAAAAATTAGGAATT
AATCATCATTTATCGTTAGAACTAAATTCAATTGGCTCTTTATCATCTAGAATAAATTATCGTAAAAAATTAATAACTTT
TTTAGAAAAAAATTTAAGCAATTTGGACAGCAATGCTCTACGTCGTTTATACTCTAATCCATTGCGTATCTTAGATACTA
AAAATACTAAAACTAAGGAATTACTACTTAATGCGCCTATATTAAGCGATTATTTAGATGATGATTCACGTGTTCATTTT
TCCGAATTATGTCAATTATTAAATCTCTTAGGAGTGCCGTACAGGGTTAATCCGTACTTAGTACGCGGTTTAGATTATTA
TAACAAAACAGTTTTTGAATGGGTTACTGATAGTTTAGGAGTAAAAAAAACTATTTGTGCTGGTGGCCGTTATGATGAAT
TAGTCCAAGAATTAGGAGGGTATTCAGCACCTGCGATAGGATTTTCCATAGGATTAGAACGTGTGATATTATTAATACAA
GAAATTAATAATATTAGCATTTTACATAAAAATATATATATTGATGTATATTTCATTAGTATAGGGGATAATTCTCGAAA
ACATGCAATGTTATTGTCTGAAAATATTCGTTCAACATTACCATCTCTGCGATTAATGGTACATCATGGAGGAGATGATA
TAAAAAAACAATTTTATTGTGCTAATAAACATAAACCACAAATCGTATTAATCATGAACGAAAAAAATGCTCTTGACAAA
ACGATTATTCTAAAAAATTTACAATCAAAAACTCAAGAAATATTAAAACATGATGCAGTTTCCGAAAGATTAAAACATAT
ACTACATATTACGTGTAATTCTACTGATAATAAATGA

Upstream 100 bases:

>100_bases
GAAGAATTAGAACGTCGTATTCGAGCTAAATCTAAATTATTAGACCCAAATAACCACAACATTACCCCTACCACATATAA
TAAATAATTGAAGATTACAA

Downstream 100 bases:

>100_bases
TCATAAAAATGATATGAATTTTTTTATAAAATATAGTATCACTAATATTTAGCGCATCTTATCAGGTTTGAAGAATATAC
ATAAAATTAAAATTATGACG

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MLKYDKNIQSVRGMHDYLPKDTILWQYIENILITILDSYGYKEIRFPIIEDTNLFKRSIGEVTDVIEKEMYNFTDRNGNN
LTLRPEGTSGCVRAGIKHGLFYHQEQRLWYLGPMFRYERPQKGRYRQFHQFSAEAFGQIGPDIDAELILITARCWKKLGI
NHHLSLELNSIGSLSSRINYRKKLITFLEKNLSNLDSNALRRLYSNPLRILDTKNTKTKELLLNAPILSDYLDDDSRVHF
SELCQLLNLLGVPYRVNPYLVRGLDYYNKTVFEWVTDSLGVKKTICAGGRYDELVQELGGYSAPAIGFSIGLERVILLIQ
EINNISILHKNIYIDVYFISIGDNSRKHAMLLSENIRSTLPSLRLMVHHGGDDIKKQFYCANKHKPQIVLIMNEKNALDK
TIILKNLQSKTQEILKHDAVSERLKHILHITCNSTDNK

Sequences:

>Translated_438_residues
MLKYDKNIQSVRGMHDYLPKDTILWQYIENILITILDSYGYKEIRFPIIEDTNLFKRSIGEVTDVIEKEMYNFTDRNGNN
LTLRPEGTSGCVRAGIKHGLFYHQEQRLWYLGPMFRYERPQKGRYRQFHQFSAEAFGQIGPDIDAELILITARCWKKLGI
NHHLSLELNSIGSLSSRINYRKKLITFLEKNLSNLDSNALRRLYSNPLRILDTKNTKTKELLLNAPILSDYLDDDSRVHF
SELCQLLNLLGVPYRVNPYLVRGLDYYNKTVFEWVTDSLGVKKTICAGGRYDELVQELGGYSAPAIGFSIGLERVILLIQ
EINNISILHKNIYIDVYFISIGDNSRKHAMLLSENIRSTLPSLRLMVHHGGDDIKKQFYCANKHKPQIVLIMNEKNALDK
TIILKNLQSKTQEILKHDAVSERLKHILHITCNSTDNK
>Mature_438_residues
MLKYDKNIQSVRGMHDYLPKDTILWQYIENILITILDSYGYKEIRFPIIEDTNLFKRSIGEVTDVIEKEMYNFTDRNGNN
LTLRPEGTSGCVRAGIKHGLFYHQEQRLWYLGPMFRYERPQKGRYRQFHQFSAEAFGQIGPDIDAELILITARCWKKLGI
NHHLSLELNSIGSLSSRINYRKKLITFLEKNLSNLDSNALRRLYSNPLRILDTKNTKTKELLLNAPILSDYLDDDSRVHF
SELCQLLNLLGVPYRVNPYLVRGLDYYNKTVFEWVTDSLGVKKTICAGGRYDELVQELGGYSAPAIGFSIGLERVILLIQ
EINNISILHKNIYIDVYFISIGDNSRKHAMLLSENIRSTLPSLRLMVHHGGDDIKKQFYCANKHKPQIVLIMNEKNALDK
TIILKNLQSKTQEILKHDAVSERLKHILHITCNSTDNK

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1788861, Length=423, Percent_Identity=56.7375886524823, Blast_Score=540, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYH_BLOPB (Q492E1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278037.1
- ProteinModelPortal:   Q492E1
- SMR:   Q492E1
- STRING:   Q492E1
- GeneID:   3562940
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_550
- eggNOG:   COG0124
- HOGENOM:   HBG616575
- OMA:   VFEWVTT
- ProtClustDB:   PRK00037
- BioCyc:   CBLO291272:BPEN_550-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00127
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516
- Gene3D:   G3DSA:3.40.50.800
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00442

Pfam domain/function: PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.21

Molecular weight: Translated: 50694; Mature: 50694

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYDKNIQSVRGMHDYLPKDTILWQYIENILITILDSYGYKEIRFPIIEDTNLFKRSIG
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
EVTDVIEKEMYNFTDRNGNNLTLRPEGTSGCVRAGIKHGLFYHQEQRLWYLGPMFRYERP
HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCEEEECCHHHCCCC
QKGRYRQFHQFSAEAFGQIGPDIDAELILITARCWKKLGINHHLSLELNSIGSLSSRINY
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHCCCCEEEEEECCHHHHHHHHHH
RKKLITFLEKNLSNLDSNALRRLYSNPLRILDTKNTKTKELLLNAPILSDYLDDDSRVHF
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHEECCCHHHHHCCCCCCCCH
SELCQLLNLLGVPYRVNPYLVRGLDYYNKTVFEWVTDSLGVKKTICAGGRYDELVQELGG
HHHHHHHHHHCCCEECCCCEEECHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHCC
YSAPAIGFSIGLERVILLIQEINNISILHKNIYIDVYFISIGDNSRKHAMLLSENIRSTL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
PSLRLMVHHGGDDIKKQFYCANKHKPQIVLIMNEKNALDKTIILKNLQSKTQEILKHDAV
HHHEEEEECCCHHHHHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SERLKHILHITCNSTDNK
HHHHHHHEEEEECCCCCC
>Mature Secondary Structure
MLKYDKNIQSVRGMHDYLPKDTILWQYIENILITILDSYGYKEIRFPIIEDTNLFKRSIG
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
EVTDVIEKEMYNFTDRNGNNLTLRPEGTSGCVRAGIKHGLFYHQEQRLWYLGPMFRYERP
HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCEEEECCHHHCCCC
QKGRYRQFHQFSAEAFGQIGPDIDAELILITARCWKKLGINHHLSLELNSIGSLSSRINY
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHCCCCEEEEEECCHHHHHHHHHH
RKKLITFLEKNLSNLDSNALRRLYSNPLRILDTKNTKTKELLLNAPILSDYLDDDSRVHF
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCCHHHHEECCCHHHHHCCCCCCCCH
SELCQLLNLLGVPYRVNPYLVRGLDYYNKTVFEWVTDSLGVKKTICAGGRYDELVQELGG
HHHHHHHHHHCCCEECCCCEEECHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHCC
YSAPAIGFSIGLERVILLIQEINNISILHKNIYIDVYFISIGDNSRKHAMLLSENIRSTL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
PSLRLMVHHGGDDIKKQFYCANKHKPQIVLIMNEKNALDKTIILKNLQSKTQEILKHDAV
HHHEEEEECCCHHHHHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SERLKHILHITCNSTDNK
HHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA