Click here to switch to the map view.

The map label for this gene is dapA

Identifier: 71892289

GI number: 71892289

Start: 641564

End: 642463

Strand: Reverse

Name: dapA

Synonym: BPEN_536

Alternate gene names: 71892289

Gene position: 642463-641564 (Counterclockwise)

Preceding gene: 71892291

Following gene: 71892288

Centisome position: 81.15

GC content: 35.67

Gene sequence:

>900_bases
ATGTTTATGGGAAGTATAGTAGCATTAATTACCCCAATGGATTTAAAGGGCACTGTAGATCGAATAAGTTTAAAAAAACT
TGTTGATCATCATGTAGTCAGTGGTACGTCAGCTATTGTTTCCGTTGGTACAACTGGAGAGATGTCTGGGCTTACACATG
AAGAGCATGTTGATGTGGTTATGCGAACCTTAGAGTTTAGCGATGGTAGATTGCCCGTTATAGCAGGTACTGGTGCTAAT
TCAACGGCAGAGGCGGTTGCATTAACTAATAAATTTAATGATAGCGATATAGCAGCTTGTTTAAGCGTAACCCCTTATTA
TAATCGTCCCAATCAAGAAGGATTATTTCAACATTTTAAGGCTATTTCAGAAAGCACAGACTTACCTCAGATATTGTATA
ACGTTCCAATACGTACTGGTTGCGATATGTTACCGATTACTGTTTCTCGCTTAGCAAAAATAAAAAATATAGTTGGTATT
AAAGAGGCGACAGGAAACTTAAATAGAGTAAATCAATTAAAACAGTTGGTTCATGAAGATTTTATTTTGTTGAGCGGAGA
TGACTTAAGTGCATTAGATTTTATGAAACTTGGAGGAGTTGGGGTAATTTCCGTTACAGCAAATATTGCTGCAAAGGAAA
TGGCTGAGTTATGTAAGTTAGCAAATGAAAATGATTTTTCAACCGCACAACACATTAATCAGCGCTTGATGCCTGTGCAC
CAAGCGCTATTTATTGATTCTAATCCTATACCAGTGAAATGGGCTTGTAAAGAATTAGGATTAATATCGCATTATGTTTT
GCGTTTACCTATGACTGTTTTATCTGAGGTACATCGTGATGTTCTAAAGCAAGCTTTAATAGATTCAGGGTTATTTTATA
ATCAGTCTAATTATAAATAA

Upstream 100 bases:

>100_bases
ACGGTTAATATTTTTATTTGATATTTTTAGCCATTTTATTTGAATGTTTTTATTGAATAACAATATTTTACAAGATTCCG
TTTATTGGAGACAATAGTTC

Downstream 100 bases:

>100_bases
TTATTTATATAAGGGTTATAATGTTAACTTTTTTAGAGATTTTGTGTATAATATTGCTATCAGCTTGTTCTTTCGGAATA
TACAAGGAAGAACGTTGTAA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MFMGSIVALITPMDLKGTVDRISLKKLVDHHVVSGTSAIVSVGTTGEMSGLTHEEHVDVVMRTLEFSDGRLPVIAGTGAN
STAEAVALTNKFNDSDIAACLSVTPYYNRPNQEGLFQHFKAISESTDLPQILYNVPIRTGCDMLPITVSRLAKIKNIVGI
KEATGNLNRVNQLKQLVHEDFILLSGDDLSALDFMKLGGVGVISVTANIAAKEMAELCKLANENDFSTAQHINQRLMPVH
QALFIDSNPIPVKWACKELGLISHYVLRLPMTVLSEVHRDVLKQALIDSGLFYNQSNYK

Sequences:

>Translated_299_residues
MFMGSIVALITPMDLKGTVDRISLKKLVDHHVVSGTSAIVSVGTTGEMSGLTHEEHVDVVMRTLEFSDGRLPVIAGTGAN
STAEAVALTNKFNDSDIAACLSVTPYYNRPNQEGLFQHFKAISESTDLPQILYNVPIRTGCDMLPITVSRLAKIKNIVGI
KEATGNLNRVNQLKQLVHEDFILLSGDDLSALDFMKLGGVGVISVTANIAAKEMAELCKLANENDFSTAQHINQRLMPVH
QALFIDSNPIPVKWACKELGLISHYVLRLPMTVLSEVHRDVLKQALIDSGLFYNQSNYK
>Mature_299_residues
MFMGSIVALITPMDLKGTVDRISLKKLVDHHVVSGTSAIVSVGTTGEMSGLTHEEHVDVVMRTLEFSDGRLPVIAGTGAN
STAEAVALTNKFNDSDIAACLSVTPYYNRPNQEGLFQHFKAISESTDLPQILYNVPIRTGCDMLPITVSRLAKIKNIVGI
KEATGNLNRVNQLKQLVHEDFILLSGDDLSALDFMKLGGVGVISVTANIAAKEMAELCKLANENDFSTAQHINQRLMPVH
QALFIDSNPIPVKWACKELGLISHYVLRLPMTVLSEVHRDVLKQALIDSGLFYNQSNYK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family

Homologues:

Organism=Homo sapiens, GI31543060, Length=289, Percent_Identity=24.9134948096886, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=70.2054794520548, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI87082415, Length=297, Percent_Identity=29.2929292929293, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786463, Length=254, Percent_Identity=28.3464566929134, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789620, Length=231, Percent_Identity=29.004329004329, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPA_BLOPB (Q492F5)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278023.1
- HSSP:   P0A6L2
- ProteinModelPortal:   Q492F5
- SMR:   Q492F5
- STRING:   Q492F5
- GeneID:   3562873
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_536
- eggNOG:   COG0329
- HOGENOM:   HBG358848
- OMA:   AQGNFVE
- ProtClustDB:   PRK03170
- BioCyc:   CBLO291272:BPEN_536-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00418
- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR12128
- PRINTS:   PR00146
- TIGRFAMs:   TIGR00674

Pfam domain/function: PF00701 DHDPS

EC number: =4.2.1.52

Molecular weight: Translated: 32701; Mature: 32701

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00665 DHDPS_1; PS00666 DHDPS_2

Important sites: ACT_SITE 161-161 BINDING 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMGSIVALITPMDLKGTVDRISLKKLVDHHVVSGTSAIVSVGTTGEMSGLTHEEHVDVV
CCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCHHHHHHHH
MRTLEFSDGRLPVIAGTGANSTAEAVALTNKFNDSDIAACLSVTPYYNRPNQEGLFQHFK
HHHHHCCCCCEEEEECCCCCCCHHHEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
AISESTDLPQILYNVPIRTGCDMLPITVSRLAKIKNIVGIKEATGNLNRVNQLKQLVHED
HHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHC
FILLSGDDLSALDFMKLGGVGVISVTANIAAKEMAELCKLANENDFSTAQHINQRLMPVH
EEEECCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QALFIDSNPIPVKWACKELGLISHYVLRLPMTVLSEVHRDVLKQALIDSGLFYNQSNYK
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFMGSIVALITPMDLKGTVDRISLKKLVDHHVVSGTSAIVSVGTTGEMSGLTHEEHVDVV
CCCCCEEHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCHHHHHHHH
MRTLEFSDGRLPVIAGTGANSTAEAVALTNKFNDSDIAACLSVTPYYNRPNQEGLFQHFK
HHHHHCCCCCEEEEECCCCCCCHHHEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
AISESTDLPQILYNVPIRTGCDMLPITVSRLAKIKNIVGIKEATGNLNRVNQLKQLVHED
HHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHC
FILLSGDDLSALDFMKLGGVGVISVTANIAAKEMAELCKLANENDFSTAQHINQRLMPVH
EEEECCCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QALFIDSNPIPVKWACKELGLISHYVLRLPMTVLSEVHRDVLKQALIDSGLFYNQSNYK
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA