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The map label for this gene is tktA [H]

Identifier: 71892286

GI number: 71892286

Start: 637742

End: 639739

Strand: Direct

Name: tktA [H]

Synonym: BPEN_533

Alternate gene names: 71892286

Gene position: 637742-639739 (Clockwise)

Preceding gene: 71892285

Following gene: 71892287

Centisome position: 80.56

GC content: 34.78

Gene sequence:

>1998_bases
ATGTTATCAGAAAAAATATTAGCTAATGCTATACGTATATTAAGCATAGATGCTATACAAAAAGCCAATTCTGGACATCC
CGGCTGTCCCATGGGCATGGCGGATATTGCTGAAGTATTGTGGAGAGATTACTTAAATCACAACCCAAACAATCCCAATT
GGATTAATAGAGACCGATTTGTTTTATCTAATGGACATGGATCAATGCTGCTATATAGCATACTACATTTAACTGGATAC
AAAATATCTATAGAAGATCTAAAAAATTTTAGACAATTAAATTCAACAACACCCGGACATCCAGAATATGGGCATACGGA
TGGAATTGAGGTTACAACAGGTCCGTTAGGGCAGGGTCTTGCTAACGCTGTAGGATTTGCAATTGCTGAACGAACACTAG
CAGCTCAATTTAATCGCGCACAGTTTAATATCATCAATCATTATACTTATGCATTTCTAGGAGATGGATGCATGATGGAA
GGTATTTCTCATGAAGCTTGCGCGCTAGCTGGGACTATGAAATTAAATAAATTGATTATATTTTACGATAATAATGGTAT
TTCTATAGACGGAAATGTACAAGAATGGTTCACAGATGATACTGCTATGCGTTTTGAATCTTATGGATGGCATGTAGTAC
GTAATGTAAATGGACATAATAGAAATTCTGTTAAAGCTGCAATTGATCAAGCTCAATCCACATTAGATAAACCATCATTG
TTAATATGTAATACTATTATTGCTTTCGGAGCTCCAAATAAAAGCGGAACACATAGCGCTCACGGCGCTCCATTAGGAGC
AGAAGAAGTGGCTGCTACTCGAAAAGCGCTTAATTGGAATGAACCTCCATTCGTCATACCAAAAGCAATATATAAATCAT
GGAATGCCACGATACCGGGACAAAAAAAAGAAGATAATTGGCAACAACTTTTTCACAAATACCAAGTTACCTATCCTAAT
TTAGCAAAGGAATTAATAAGAAGAATACAACGAAAACTACCCGAAGATTGGCATAAAAAAACACAAAAATTTATTGAAAA
TTTACAAATGCATTCTCAAAATATTGCTACACGTCAAGCTTCTCAAATTACAATTGAATTTTTTTCCAAAGAATTACCAG
AGCTTTTTGGTGGATCATCAGACTTAACACCCAGCAATTTGACAACTTGGTCTCAATCTTCTTCTATTATGAAAAATCCT
GCCGGAAATTATATTCATTACGGTGTACGTGAATTCGGGATGACTGCTATTGCCAATGGAATTGCTAATTATGGAGCTTT
TTTACCTTATACTGCTACATTTTTAACATTTGTTGAATACGCACGCAACGCGGTTCGCATGGCGGCATTAATGAATAGTC
ATCATATTATGATTTATACTCATGATTCTATTGGATTAGGAGAAGATGGTCCAACTCATCAACCTATAGAACAATTATCA
AGTTTACGTATGACTCCCAATTTAATAGTATGGCGTCCCTGTGATCAAGTAGAAACAGCAATTGCCTGGAAATCAGCAAT
TGAACACCATGGGCCAACCGCATTGATTTTATCTAGACAAAATCTCATGCAGCAAGAACGCACATCAACACAAATTAATA
ACATTAATCGCGGAGGATATATTCTTAAAGATTGTCAAAATATCCCTGAATTAATTATAATTGCTACTGGGTCAGAAATA
ATATTAGCAATACAAGCATATTACCGATTAACTGATGAAGGCTATAAAATACGAGTCATCTCGTTACCTTCTACTAATAT
ATTTGATCAGCAAGATAAATCATATCGTGAATACGTATTACCAAGCACAATAATTAATAGAATAGCTATCGAAGCTAGTA
GCACTGACTATTGGTATAAGTATGTTGGAATATATGGTGAAATCATTGGTATGAAGACATTCGGAAAATCAGCTCCATCA
CATCAATTATTTAAATTTTTTGACTTTACTGTGGACTACGTGATCAATAAATCATATAAATTACTCAAAAAATCCTAA

Upstream 100 bases:

>100_bases
TAAGTATGGAAAAATTCACTAAACATATTCGATAATTCTCTATAAGAGAGAAGAATTTATAATCATTTAATTAAAACATT
CAATATTAGGAAAATACTTT

Downstream 100 bases:

>100_bases
AACAACAGATCACCAAAAATGTTTAATTTTTATAAAAAACATCTATATACAACTATATCAATAAATATCGGTATAGTTGT
ATATCTGAATTTTACATTGA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MLSEKILANAIRILSIDAIQKANSGHPGCPMGMADIAEVLWRDYLNHNPNNPNWINRDRFVLSNGHGSMLLYSILHLTGY
KISIEDLKNFRQLNSTTPGHPEYGHTDGIEVTTGPLGQGLANAVGFAIAERTLAAQFNRAQFNIINHYTYAFLGDGCMME
GISHEACALAGTMKLNKLIIFYDNNGISIDGNVQEWFTDDTAMRFESYGWHVVRNVNGHNRNSVKAAIDQAQSTLDKPSL
LICNTIIAFGAPNKSGTHSAHGAPLGAEEVAATRKALNWNEPPFVIPKAIYKSWNATIPGQKKEDNWQQLFHKYQVTYPN
LAKELIRRIQRKLPEDWHKKTQKFIENLQMHSQNIATRQASQITIEFFSKELPELFGGSSDLTPSNLTTWSQSSSIMKNP
AGNYIHYGVREFGMTAIANGIANYGAFLPYTATFLTFVEYARNAVRMAALMNSHHIMIYTHDSIGLGEDGPTHQPIEQLS
SLRMTPNLIVWRPCDQVETAIAWKSAIEHHGPTALILSRQNLMQQERTSTQINNINRGGYILKDCQNIPELIIIATGSEI
ILAIQAYYRLTDEGYKIRVISLPSTNIFDQQDKSYREYVLPSTIINRIAIEASSTDYWYKYVGIYGEIIGMKTFGKSAPS
HQLFKFFDFTVDYVINKSYKLLKKS

Sequences:

>Translated_665_residues
MLSEKILANAIRILSIDAIQKANSGHPGCPMGMADIAEVLWRDYLNHNPNNPNWINRDRFVLSNGHGSMLLYSILHLTGY
KISIEDLKNFRQLNSTTPGHPEYGHTDGIEVTTGPLGQGLANAVGFAIAERTLAAQFNRAQFNIINHYTYAFLGDGCMME
GISHEACALAGTMKLNKLIIFYDNNGISIDGNVQEWFTDDTAMRFESYGWHVVRNVNGHNRNSVKAAIDQAQSTLDKPSL
LICNTIIAFGAPNKSGTHSAHGAPLGAEEVAATRKALNWNEPPFVIPKAIYKSWNATIPGQKKEDNWQQLFHKYQVTYPN
LAKELIRRIQRKLPEDWHKKTQKFIENLQMHSQNIATRQASQITIEFFSKELPELFGGSSDLTPSNLTTWSQSSSIMKNP
AGNYIHYGVREFGMTAIANGIANYGAFLPYTATFLTFVEYARNAVRMAALMNSHHIMIYTHDSIGLGEDGPTHQPIEQLS
SLRMTPNLIVWRPCDQVETAIAWKSAIEHHGPTALILSRQNLMQQERTSTQINNINRGGYILKDCQNIPELIIIATGSEI
ILAIQAYYRLTDEGYKIRVISLPSTNIFDQQDKSYREYVLPSTIINRIAIEASSTDYWYKYVGIYGEIIGMKTFGKSAPS
HQLFKFFDFTVDYVINKSYKLLKKS
>Mature_665_residues
MLSEKILANAIRILSIDAIQKANSGHPGCPMGMADIAEVLWRDYLNHNPNNPNWINRDRFVLSNGHGSMLLYSILHLTGY
KISIEDLKNFRQLNSTTPGHPEYGHTDGIEVTTGPLGQGLANAVGFAIAERTLAAQFNRAQFNIINHYTYAFLGDGCMME
GISHEACALAGTMKLNKLIIFYDNNGISIDGNVQEWFTDDTAMRFESYGWHVVRNVNGHNRNSVKAAIDQAQSTLDKPSL
LICNTIIAFGAPNKSGTHSAHGAPLGAEEVAATRKALNWNEPPFVIPKAIYKSWNATIPGQKKEDNWQQLFHKYQVTYPN
LAKELIRRIQRKLPEDWHKKTQKFIENLQMHSQNIATRQASQITIEFFSKELPELFGGSSDLTPSNLTTWSQSSSIMKNP
AGNYIHYGVREFGMTAIANGIANYGAFLPYTATFLTFVEYARNAVRMAALMNSHHIMIYTHDSIGLGEDGPTHQPIEQLS
SLRMTPNLIVWRPCDQVETAIAWKSAIEHHGPTALILSRQNLMQQERTSTQINNINRGGYILKDCQNIPELIIIATGSEI
ILAIQAYYRLTDEGYKIRVISLPSTNIFDQQDKSYREYVLPSTIINRIAIEASSTDYWYKYVGIYGEIIGMKTFGKSAPS
HQLFKFFDFTVDYVINKSYKLLKKS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=694, Percent_Identity=26.657060518732, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI4507521, Length=694, Percent_Identity=26.657060518732, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI133778974, Length=575, Percent_Identity=26.2608695652174, Blast_Score=136, Evalue=7e-32,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=65.6108597285068, Blast_Score=960, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=662, Percent_Identity=63.8972809667674, Blast_Score=930, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=579, Percent_Identity=25.0431778929188, Blast_Score=161, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=671, Percent_Identity=47.0938897168405, Blast_Score=605, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=45.5489614243323, Blast_Score=585, Evalue=1e-168,
Organism=Drosophila melanogaster, GI45551847, Length=683, Percent_Identity=25.9150805270864, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45550715, Length=683, Percent_Identity=25.9150805270864, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24645119, Length=649, Percent_Identity=24.9614791987673, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24666278, Length=586, Percent_Identity=24.061433447099, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74799; Mature: 74799

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEKILANAIRILSIDAIQKANSGHPGCPMGMADIAEVLWRDYLNHNPNNPNWINRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLSNGHGSMLLYSILHLTGYKISIEDLKNFRQLNSTTPGHPEYGHTDGIEVTTGPLGQGL
EEECCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHH
ANAVGFAIAERTLAAQFNRAQFNIINHYTYAFLGDGCMMEGISHEACALAGTMKLNKLII
HHHHHHHHHHHHHHHHHCCCEEEEEHHEEEEEECCCHHHCCCCCHHHHHHHEEEEEEEEE
FYDNNGISIDGNVQEWFTDDTAMRFESYGWHVVRNVNGHNRNSVKAAIDQAQSTLDKPSL
EECCCCEEECCCHHHHHCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
LICNTIIAFGAPNKSGTHSAHGAPLGAEEVAATRKALNWNEPPFVIPKAIYKSWNATIPG
EEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCC
QKKEDNWQQLFHKYQVTYPNLAKELIRRIQRKLPEDWHKKTQKFIENLQMHSQNIATRQA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SQITIEFFSKELPELFGGSSDLTPSNLTTWSQSSSIMKNPAGNYIHYGVREFGMTAIANG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHH
IANYGAFLPYTATFLTFVEYARNAVRMAALMNSHHIMIYTHDSIGLGEDGPTHQPIEQLS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHH
SLRMTPNLIVWRPCDQVETAIAWKSAIEHHGPTALILSRQNLMQQERTSTQINNINRGGY
HCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCE
ILKDCQNIPELIIIATGSEIILAIQAYYRLTDEGYKIRVISLPSTNIFDQQDKSYREYVL
EHHHHCCCCCEEEEECCCCEEEHEEHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHCC
PSTIINRIAIEASSTDYWYKYVGIYGEIIGMKTFGKSAPSHQLFKFFDFTVDYVINKSYK
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
LLKKS
HHCCC
>Mature Secondary Structure
MLSEKILANAIRILSIDAIQKANSGHPGCPMGMADIAEVLWRDYLNHNPNNPNWINRDRF
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLSNGHGSMLLYSILHLTGYKISIEDLKNFRQLNSTTPGHPEYGHTDGIEVTTGPLGQGL
EEECCCCHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHH
ANAVGFAIAERTLAAQFNRAQFNIINHYTYAFLGDGCMMEGISHEACALAGTMKLNKLII
HHHHHHHHHHHHHHHHHCCCEEEEEHHEEEEEECCCHHHCCCCCHHHHHHHEEEEEEEEE
FYDNNGISIDGNVQEWFTDDTAMRFESYGWHVVRNVNGHNRNSVKAAIDQAQSTLDKPSL
EECCCCEEECCCHHHHHCCCHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
LICNTIIAFGAPNKSGTHSAHGAPLGAEEVAATRKALNWNEPPFVIPKAIYKSWNATIPG
EEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCC
QKKEDNWQQLFHKYQVTYPNLAKELIRRIQRKLPEDWHKKTQKFIENLQMHSQNIATRQA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SQITIEFFSKELPELFGGSSDLTPSNLTTWSQSSSIMKNPAGNYIHYGVREFGMTAIANG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEHHHHHHHHHHHHHH
IANYGAFLPYTATFLTFVEYARNAVRMAALMNSHHIMIYTHDSIGLGEDGPTHQPIEQLS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHH
SLRMTPNLIVWRPCDQVETAIAWKSAIEHHGPTALILSRQNLMQQERTSTQINNINRGGY
HCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCE
ILKDCQNIPELIIIATGSEIILAIQAYYRLTDEGYKIRVISLPSTNIFDQQDKSYREYVL
EHHHHCCCCCEEEEECCCCEEEHEEHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHCC
PSTIINRIAIEASSTDYWYKYVGIYGEIIGMKTFGKSAPSHQLFKFFDFTVDYVINKSYK
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHH
LLKKS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8241274; 9278503; 2153656 [H]