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The map label for this gene is mntH

Identifier: 71892274

GI number: 71892274

Start: 620543

End: 621778

Strand: Reverse

Name: mntH

Synonym: BPEN_518

Alternate gene names: 71892274

Gene position: 621778-620543 (Counterclockwise)

Preceding gene: 71892276

Following gene: 71892271

Centisome position: 78.54

GC content: 33.58

Gene sequence:

>1236_bases
ATGCTAAATGAGCAAGATTCAGTAACGGAACATCGTTCTAGAAGAAAAATCAAATTCGCGTTGCTTGGTCCTGCTTTTAT
AGCTGCTATTGGGTATATCGATCCTGGAAATTTTGCAACTAATATACAAGCTGGAGCTACTTTTGGTTATCAGTTACTGT
GGGTTGTAGTATGGGCAAATATAATGGCTATGCTAATTCAATTACTTTCTGCAAAATTAGGTATTGCTACTGGTAAAAAT
TTGGCAGAACATATTCGAGATCAATTTCCAAGATCAGTGGTATGGATGTATTGGATTCAAGCTGAAATTATTGCTATGGC
TACAGACTTAGCAGAATTTATTGGAGCTGCTATTGGATTTAAAATATTGCTCGGTATACCTTTATTACAAGGTGCATTAT
TAACGGGCTTGATTACTTTTTTAATTTTAACTTTACAAAGATACGGAAAAAAACCATTAGAATTTGTTGTGGGAGGTTTA
TTATTTTTTGTTGCAATTGCTTATGTTATTGAACTTTTTTATTCGAAACCTAAATTTATTATGTTAGGTATGAGCATGTT
ACTTCCAATACTTCCAAATAGAGAAGCAGTTTTTTTGTCAGCAGGGGTGTTAGGTGCTACAATTATGCCACATGTTATTT
ATTTACATTCTTCTCTTACTCAGGATGAGAGTAAGACCGCAAGTAGATCGGAGCGATATTCTTCTACGAAATTGGATGTC
GCAATCGCAATGACTATTGCTGGCTTTGTAAATCTATCTATGATGGCTACTGCAGCGGCAGTGTTTCATTATGGTGGATA
TACTGGCATTTCTAATTTAGATGAAGCTTATTTAACATTGTCTCCTTTGTTAAATCATACTGCTGCTATAGTTTTCGGTT
TAAGTTTAACAGCAGCTGGATTATCTTCAACAGTAGTAGGTACTTTGGCGGGTCAAGTGGTCATGCAAGGATTTGTTCGT
TTTCATATTCCTTTGTTGTTGCGCCGTGTTATTACCATGCTGCCGTCATTTATAGTTATTTCTTTTGGAATTGATTCCAC
ACGTATTTTAATAATGAGTCAAGTACTACTTAGTTTTGGAATTGCACTTGCGTTAATACCGTTGTTAGTATTTACTGGAA
ATGTTAAATTAATGAATGAATTAGTGAATTCTTTATGGATTAAATTGATTGGTTGGTTAATAACAATAGTGGTAATAATT
TTGAATATATATTTATTAATTGGCATTATTATTTGA

Upstream 100 bases:

>100_bases
TCAAATTCGATCTCTAATTATATACCCATTATAGTACAATTACTTTATTTAATGTATATAAAATAAGCTCGAATAAGATG
ATTCTATAAGGATTATCAGT

Downstream 100 bases:

>100_bases
TAAATAATACATTAATATAGGTGATTGCTTTAAAAATTTTCTGTTTTATCGCGTCTTGGTTCACTATGTATGTTTTCGTT
ATTATTAAAATTTGTTTTAA

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLNEQDSVTEHRSRRKIKFALLGPAFIAAIGYIDPGNFATNIQAGATFGYQLLWVVVWANIMAMLIQLLSAKLGIATGKN
LAEHIRDQFPRSVVWMYWIQAEIIAMATDLAEFIGAAIGFKILLGIPLLQGALLTGLITFLILTLQRYGKKPLEFVVGGL
LFFVAIAYVIELFYSKPKFIMLGMSMLLPILPNREAVFLSAGVLGATIMPHVIYLHSSLTQDESKTASRSERYSSTKLDV
AIAMTIAGFVNLSMMATAAAVFHYGGYTGISNLDEAYLTLSPLLNHTAAIVFGLSLTAAGLSSTVVGTLAGQVVMQGFVR
FHIPLLLRRVITMLPSFIVISFGIDSTRILIMSQVLLSFGIALALIPLLVFTGNVKLMNELVNSLWIKLIGWLITIVVII
LNIYLLIGIII

Sequences:

>Translated_411_residues
MLNEQDSVTEHRSRRKIKFALLGPAFIAAIGYIDPGNFATNIQAGATFGYQLLWVVVWANIMAMLIQLLSAKLGIATGKN
LAEHIRDQFPRSVVWMYWIQAEIIAMATDLAEFIGAAIGFKILLGIPLLQGALLTGLITFLILTLQRYGKKPLEFVVGGL
LFFVAIAYVIELFYSKPKFIMLGMSMLLPILPNREAVFLSAGVLGATIMPHVIYLHSSLTQDESKTASRSERYSSTKLDV
AIAMTIAGFVNLSMMATAAAVFHYGGYTGISNLDEAYLTLSPLLNHTAAIVFGLSLTAAGLSSTVVGTLAGQVVMQGFVR
FHIPLLLRRVITMLPSFIVISFGIDSTRILIMSQVLLSFGIALALIPLLVFTGNVKLMNELVNSLWIKLIGWLITIVVII
LNIYLLIGIII
>Mature_411_residues
MLNEQDSVTEHRSRRKIKFALLGPAFIAAIGYIDPGNFATNIQAGATFGYQLLWVVVWANIMAMLIQLLSAKLGIATGKN
LAEHIRDQFPRSVVWMYWIQAEIIAMATDLAEFIGAAIGFKILLGIPLLQGALLTGLITFLILTLQRYGKKPLEFVVGGL
LFFVAIAYVIELFYSKPKFIMLGMSMLLPILPNREAVFLSAGVLGATIMPHVIYLHSSLTQDESKTASRSERYSSTKLDV
AIAMTIAGFVNLSMMATAAAVFHYGGYTGISNLDEAYLTLSPLLNHTAAIVFGLSLTAAGLSSTVVGTLAGQVVMQGFVR
FHIPLLLRRVITMLPSFIVISFGIDSTRILIMSQVLLSFGIALALIPLLVFTGNVKLMNELVNSLWIKLIGWLITIVVII
LNIYLLIGIII

Specific function: H(+)-stimulated, highly selective, manganese uptake system

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family

Homologues:

Organism=Homo sapiens, GI109255241, Length=433, Percent_Identity=32.3325635103926, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI295293178, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI295293175, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293173, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI10835169, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293167, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293171, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293169, Length=451, Percent_Identity=30.3769401330377, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1788736, Length=408, Percent_Identity=73.5294117647059, Blast_Score=595, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI17569473, Length=393, Percent_Identity=32.5699745547074, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI193210616, Length=445, Percent_Identity=29.8876404494382, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71999499, Length=446, Percent_Identity=30.2690582959641, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71993856, Length=412, Percent_Identity=26.9417475728155, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323062, Length=403, Percent_Identity=34.7394540942928, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324450, Length=436, Percent_Identity=27.7522935779816, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321841, Length=446, Percent_Identity=30.7174887892377, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24648607, Length=446, Percent_Identity=33.1838565022422, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281362176, Length=446, Percent_Identity=33.1838565022422, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24648609, Length=446, Percent_Identity=33.1838565022422, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI45553443, Length=424, Percent_Identity=32.7830188679245, Blast_Score=209, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNTH_BLOPB (Q492G8)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278008.1
- STRING:   Q492G8
- GeneID:   3563143
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_518
- eggNOG:   COG1914
- HOGENOM:   HBG312498
- OMA:   AYIVELV
- ProtClustDB:   PRK00701
- BioCyc:   CBLO291272:BPEN_518-MONOMER
- HAMAP:   MF_00221
- InterPro:   IPR023056
- InterPro:   IPR001046
- PANTHER:   PTHR11706
- PRINTS:   PR00447
- TIGRFAMs:   TIGR01197

Pfam domain/function: PF01566 Nramp

EC number: NA

Molecular weight: Translated: 44883; Mature: 44883

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11ec0ecc)-; HASH(0x1195d768)-; HASH(0x11d37d38)-; HASH(0x11a82878)-; HASH(0x112dd4d8)-; HASH(0x11e767ac)-; HASH(0x11ef55f4)-; HASH(0x116fd56c)-; HASH(0x11d1efe8)-; HASH(0x1175b744)-; HASH(0x11ee4634)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEQDSVTEHRSRRKIKFALLGPAFIAAIGYIDPGNFATNIQAGATFGYQLLWVVVWAN
CCCCCHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IMAMLIQLLSAKLGIATGKNLAEHIRDQFPRSVVWMYWIQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILLGIPLLQGALLTGLITFLILTLQRYGKKPLEFVVGGLLFFVAIAYVIELFYSKPKFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
MLGMSMLLPILPNREAVFLSAGVLGATIMPHVIYLHSSLTQDESKTASRSERYSSTKLDV
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
AIAMTIAGFVNLSMMATAAAVFHYGGYTGISNLDEAYLTLSPLLNHTAAIVFGLSLTAAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSTVVGTLAGQVVMQGFVRFHIPLLLRRVITMLPSFIVISFGIDSTRILIMSQVLLSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHH
IALALIPLLVFTGNVKLMNELVNSLWIKLIGWLITIVVIILNIYLLIGIII
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MLNEQDSVTEHRSRRKIKFALLGPAFIAAIGYIDPGNFATNIQAGATFGYQLLWVVVWAN
CCCCCHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
IMAMLIQLLSAKLGIATGKNLAEHIRDQFPRSVVWMYWIQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILLGIPLLQGALLTGLITFLILTLQRYGKKPLEFVVGGLLFFVAIAYVIELFYSKPKFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
MLGMSMLLPILPNREAVFLSAGVLGATIMPHVIYLHSSLTQDESKTASRSERYSSTKLDV
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
AIAMTIAGFVNLSMMATAAAVFHYGGYTGISNLDEAYLTLSPLLNHTAAIVFGLSLTAAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSTVVGTLAGQVVMQGFVRFHIPLLLRRVITMLPSFIVISFGIDSTRILIMSQVLLSFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHH
IALALIPLLVFTGNVKLMNELVNSLWIKLIGWLITIVVIILNIYLLIGIII
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA