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The map label for this gene is nuoE [H]

Identifier: 71892263

GI number: 71892263

Start: 606312

End: 606833

Strand: Reverse

Name: nuoE [H]

Synonym: BPEN_506

Alternate gene names: 71892263

Gene position: 606833-606312 (Counterclockwise)

Preceding gene: 71892264

Following gene: 71892262

Centisome position: 76.65

GC content: 32.38

Gene sequence:

>522_bases
ATGAGTAATATTAAAATTAATGATATGTCCACTAGTTTAACTAGTAATGGTTTTTTTCAATTAAGTCAAGAAGAATGTAA
TGCTATTCAAGAAGAATGTACACATTATGAAGATATGCGCGCGGTTTCTATTGAAGCGTTAAAAATTATTCAAAAAAATC
ATGGGTGGGTACCAGATGAAGCAATTATATTGATTGCTAAAATATTATGTATTTCTGCCGCTGATCTAGAAGGTGTCGCA
ACATTTTATAATCAAATTTTTCGTCAACCGGTAGGTCGTCATATCATTAGGTATTGTGATAGCGCGGTATGCTACTTGGT
TGGGTGTGAAAAAATCAAAAACACTTTAACATATCTGTTGAATATTACAGTGGGTAGCACAACTTCAGATAATCGCTTTA
CCTTATTGCCTACTTGTTGTTTAGGTATTTGCGACAAAGCTCCAGTCATTATGATAGACAAAGATATTTATCCTTATATA
GTTCCGGAAACAATTACAAAATTGTTAGGACAGTATTTATGA

Upstream 100 bases:

>100_bases
CCACATGTTATTCGTGGTAGTTTAATATCTGATTTAATTGTGTATTTAGGTAGTATTGATTTTGTTATGTCTGATGTAGA
TCGTTAATAAATGGAGAAAT

Downstream 100 bases:

>100_bases
GCAATACTTATGATGTTAGTGCAGAAAATAATCCACTTACATGGAGAATGCGTGACGATAAACAACCAGTATGGTTGCAT
GAATATAAATCTAAAAATGG

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E; NUO5 [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSNIKINDMSTSLTSNGFFQLSQEECNAIQEECTHYEDMRAVSIEALKIIQKNHGWVPDEAIILIAKILCISAADLEGVA
TFYNQIFRQPVGRHIIRYCDSAVCYLVGCEKIKNTLTYLLNITVGSTTSDNRFTLLPTCCLGICDKAPVIMIDKDIYPYI
VPETITKLLGQYL

Sequences:

>Translated_173_residues
MSNIKINDMSTSLTSNGFFQLSQEECNAIQEECTHYEDMRAVSIEALKIIQKNHGWVPDEAIILIAKILCISAADLEGVA
TFYNQIFRQPVGRHIIRYCDSAVCYLVGCEKIKNTLTYLLNITVGSTTSDNRFTLLPTCCLGICDKAPVIMIDKDIYPYI
VPETITKLLGQYL
>Mature_172_residues
SNIKINDMSTSLTSNGFFQLSQEECNAIQEECTHYEDMRAVSIEALKIIQKNHGWVPDEAIILIAKILCISAADLEGVAT
FYNQIFRQPVGRHIIRYCDSAVCYLVGCEKIKNTLTYLLNITVGSTTSDNRFTLLPTCCLGICDKAPVIMIDKDIYPYIV
PETITKLLGQYL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=141, Percent_Identity=32.6241134751773, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788621, Length=154, Percent_Identity=61.6883116883117, Blast_Score=202, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17561328, Length=153, Percent_Identity=36.6013071895425, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859877, Length=141, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355353, Length=141, Percent_Identity=28.3687943262411, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19423; Mature: 19292

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIKINDMSTSLTSNGFFQLSQEECNAIQEECTHYEDMRAVSIEALKIIQKNHGWVPDE
CCCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AIILIAKILCISAADLEGVATFYNQIFRQPVGRHIIRYCDSAVCYLVGCEKIKNTLTYLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NITVGSTTSDNRFTLLPTCCLGICDKAPVIMIDKDIYPYIVPETITKLLGQYL
EEEECCCCCCCCEEEHHHHHHHHCCCCCEEEEECCCCCEECHHHHHHHHHHCC
>Mature Secondary Structure 
SNIKINDMSTSLTSNGFFQLSQEECNAIQEECTHYEDMRAVSIEALKIIQKNHGWVPDE
CCCEECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AIILIAKILCISAADLEGVATFYNQIFRQPVGRHIIRYCDSAVCYLVGCEKIKNTLTYLL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NITVGSTTSDNRFTLLPTCCLGICDKAPVIMIDKDIYPYIVPETITKLLGQYL
EEEECCCCCCCCEEEHHHHHHHHCCCCCEEEEECCCCCEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]