Click here to switch to the map view.

The map label for this gene is nrdB [H]

Identifier: 71892252

GI number: 71892252

Start: 593153

End: 594283

Strand: Direct

Name: nrdB [H]

Synonym: BPEN_495

Alternate gene names: 71892252

Gene position: 593153-594283 (Clockwise)

Preceding gene: 71892251

Following gene: 71892253

Centisome position: 74.93

GC content: 32.1

Gene sequence:

>1131_bases
ATGATTTATACAACTTTTTCTCAAAATAAAAATAATCAACTGCTCGAACCGATGTTTTTAGGACAACCAGTAAATATCGC
TCGATTTGATCAACAAAAACATTCCATTTTCGAAAAATTAATTGAAAAACAACTTTCGTTCTTTTGGCGCCCAGAAGAAA
TAGATATTTCTAAAGACCGTATAGATTTTCAATCATTACCAGACCATGAAAAACACATTTTTATTAGCAATTTAAAATAC
CAAACTTTATTAGATTCTATTCAAGGACGCAGTCCCAATATTGCATTATTACCATTAATTTCTATACCAGAACTGGAAAT
TTGGGTAGAAACTTGGTCATTTTTTGAAACCATTCACTCCCGTTCCTACACCCATATTATTCGTAATATTGTTAATCACC
CATCTTTGATATTTGATGATATTATCAGCAACAAAGAAATTTTAAAACGTGCTAAAGATATTTCGACGTACTATGATAAT
TTAATTGAATTAACCAGTTATTATCATATCTTAGGCCCCGGTATTCATCAAATCAATAATAACACTGTCGCAGTAAACTT
ACATGAACTTAAAAAGAAATTATATTTATGTTTGATTAGCGTTAACGTCCTAGAAGCTATTCGTTTTTATGTCAGCTTTG
CCTGTTCTTTTGCATTTGCTGAACGAGAACTCATGGAAGGTAATGCAAAAATTATACGACTTATAGCACGTGACGAAGCT
TTGCATTTAAACGCTACTCAACATATTTTAAACTTAATGCGCTCTGGATCAGATGATCCAGAAATGGCCGATATCAGTAC
AGAATGCCAACAAGAAAGTTATGCGCTGTTTTTAATGGCTGCAGAACAAGAAAAAAATTGGGCTAACTATTTATTTAAAG
ATGGCTCTATGATAGGTTTAAATAAAGATATACTTTGTCAATATATTGAATATATTACCAATATACGCATGCAAGCAATC
GGGCTAAGAACACCCTTCAACATTAAATCTAACGTGATACCATGGATTAATTCTTGGTTATCATCAGATAATGTTCAAGT
GGCGCCACAAGAAGTAGAAGCCAGTTCTTATCTAGTAGGCCAAATAGATCCTAATATTGACGAAAATGAATTTCATGACT
TTCAATTGTAA

Upstream 100 bases:

>100_bases
ATAACCAATCAAATATTTGTACAAGTGATGCTTGTACAATTTAGAAAAGTAACTACTATTTACTAAAACCTACATATTTA
TTTTTAAAAAAGGAATAAAA

Downstream 100 bases:

>100_bases
AATATTTTTTCTTCAAAAAAAATATTTAAATATACAATTTGCGCATAACAACAGAATGTATCGTTCCTTATTAGAAGCAT
TGGAAATGCATCATATACCA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Protein B2; Protein R2; Ribonucleotide reductase 1 [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWRPEEIDISKDRIDFQSLPDHEKHIFISNLKY
QTLLDSIQGRSPNIALLPLISIPELEIWVETWSFFETIHSRSYTHIIRNIVNHPSLIFDDIISNKEILKRAKDISTYYDN
LIELTSYYHILGPGIHQINNNTVAVNLHELKKKLYLCLISVNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEA
LHLNATQHILNLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGLNKDILCQYIEYITNIRMQAI
GLRTPFNIKSNVIPWINSWLSSDNVQVAPQEVEASSYLVGQIDPNIDENEFHDFQL

Sequences:

>Translated_376_residues
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWRPEEIDISKDRIDFQSLPDHEKHIFISNLKY
QTLLDSIQGRSPNIALLPLISIPELEIWVETWSFFETIHSRSYTHIIRNIVNHPSLIFDDIISNKEILKRAKDISTYYDN
LIELTSYYHILGPGIHQINNNTVAVNLHELKKKLYLCLISVNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEA
LHLNATQHILNLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGLNKDILCQYIEYITNIRMQAI
GLRTPFNIKSNVIPWINSWLSSDNVQVAPQEVEASSYLVGQIDPNIDENEFHDFQL
>Mature_376_residues
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWRPEEIDISKDRIDFQSLPDHEKHIFISNLKY
QTLLDSIQGRSPNIALLPLISIPELEIWVETWSFFETIHSRSYTHIIRNIVNHPSLIFDDIISNKEILKRAKDISTYYDN
LIELTSYYHILGPGIHQINNNTVAVNLHELKKKLYLCLISVNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEA
LHLNATQHILNLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGLNKDILCQYIEYITNIRMQAI
GLRTPFNIKSNVIPWINSWLSSDNVQVAPQEVEASSYLVGQIDPNIDENEFHDFQL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1788567, Length=376, Percent_Identity=78.1914893617021, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 43712; Mature: 43712

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWRPEEIDISKDR
CEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IDFQSLPDHEKHIFISNLKYQTLLDSIQGRSPNIALLPLISIPELEIWVETWSFFETIHS
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHC
RSYTHIIRNIVNHPSLIFDDIISNKEILKRAKDISTYYDNLIELTSYYHILGPGIHQINN
CHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
NTVAVNLHELKKKLYLCLISVNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCE
LHLNATQHILNLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGL
EECCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHCCCCCEECC
NKDILCQYIEYITNIRMQAIGLRTPFNIKSNVIPWINSWLSSDNVQVAPQEVEASSYLVG
CHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCHHHHHHHHCCCCCEECHHHHCCCCEEEE
QIDPNIDENEFHDFQL
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIYTTFSQNKNNQLLEPMFLGQPVNIARFDQQKHSIFEKLIEKQLSFFWRPEEIDISKDR
CEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IDFQSLPDHEKHIFISNLKYQTLLDSIQGRSPNIALLPLISIPELEIWVETWSFFETIHS
CCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHC
RSYTHIIRNIVNHPSLIFDDIISNKEILKRAKDISTYYDNLIELTSYYHILGPGIHQINN
CHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECC
NTVAVNLHELKKKLYLCLISVNVLEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEA
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCE
LHLNATQHILNLMRSGSDDPEMADISTECQQESYALFLMAAEQEKNWANYLFKDGSMIGL
EECCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCHHHHHCCCCCEECC
NKDILCQYIEYITNIRMQAIGLRTPFNIKSNVIPWINSWLSSDNVQVAPQEVEASSYLVG
CHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCHHHHHHHHCCCCCEECHHHHCCCCEEEE
QIDPNIDENEFHDFQL
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]