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The map label for this gene is aspS

Identifier: 71892229

GI number: 71892229

Start: 556853

End: 558577

Strand: Reverse

Name: aspS

Synonym: BPEN_467

Alternate gene names: 71892229

Gene position: 558577-556853 (Counterclockwise)

Preceding gene: 71892231

Following gene: 71892228

Centisome position: 70.56

GC content: 31.07

Gene sequence:

>1725_bases
ATGCGTACTGCATATTGTGGTCAATTGAATTTGTCCCATGTAGGTTTAGAAGTTACATTATGCGGTTGGATTAATAAATA
TCGTAATTTTGGTGGGTTAATTTTTATTGATTTACGTGATAGAGAGGGATGTATACAGGTTTGTTTTGATGTATATCAAA
ACAAAGAAGTGTGTATATCTGCTGCTAAATTGAAACAAGAATTTTGTATACAGTTAATAGGTATGGTGCGCGCCCGCCCT
AAAAATCAAATTAATAGTAATATATCTACCGGTGCTGTTGAAGTAGTAGCGAAAAAATTTTCTATTCTTAATATTTCTGA
TCCATTACCATTGGATATTAGTAAAAATAATATTGAAGAAAATAGACTAAAATATCGTTATCTTGACTTAAGACGTTCTA
TTATGTTTGATCGAATAAAAACTCGATCGCGTATTATGTCAATTGTGCATCGTTTTATGGAATTAGAAGGATTTTTAAAT
ATCGAAACACCGATGTTAACAAAAGTTACTCCAGAAGGTTCTCGTGATTATATTGTTCCTAGTAGATTACATGCGGGTAA
AAATTATGCTTTACCTCAATCACCTCAAATATTTAAACAATTATTAATGGTTTCTGGTTTTGATAGATATTATCAAATTA
CTAAATGTTTTCGGGATGAAGATTTACGTGCAGATCGTCAGCCAGAGTTTACGCAAATAGATATTGAAACTTCTTTTATG
ACAACACAAAAAATACGAGAACTTATGGAAATTTTTATTCGTATCATTTGGCGTGAAATTTTAAACGTAGAATTGGGAGT
ATTTTCGCAGTTTACATATTCTGAAGTAATGCAGCGTTTTGGATCTGATGCTCCAGATTTGAGAAATCCAATAGAAATGT
TTGATGTATCATATTTATTTAATTCAACACAAAATAGGTTGTCATTTATTAGAGCAAATAATATTGGTGTACAGGCAATA
GCTATGAAGGTGCCTAATGGTAGACAACTGACACAAAAACAGATCGATGAGTATATTTATTATTCTAAACAATGTGGTTT
GAAGGAATTACTGTGGGTTAAGGTTCAATTTAGTGACAATGATATTACTAAAAAAGAGATTCAAGGATCAGTCACTAATT
TTATAGATAACTTAACTTTAGATATTATTTTAAATAAAACTAATATTAAAAGTAATGATATTTTGTTTGTTGGGTTTAAT
GATAATAAAAACCAATTTATCACAAAAATGTTAAGTGCTTTAAGATTAAAATTAGGTAATGATCTTTGTTTAATTAAGAA
AGATTCTTGGGCTCCGCTATGGATAATAGATTTCCCGATGTTTAAAAAGAACTGTCATGGAGAATATACATCTATGCACC
ATATGTTTACTTCTCCAAAAAATTGTGATGTTCAAATGTTAAAGAAAGATCCGTTATTAGTAATTTCAGAAGCTTATGAT
ATGGTGATTAATGGTTGTGAGATTGGTAGTGGATCAGCGCGTATCCATTCATTTGATATGCAACAAGCGGTATTTAACAT
TTTAGGTATTACTCAAAACGATCAGAAAAAAAAATTTGGGTATTTCATGGATGCATTAAAATATGGAGCGCCTCCACATG
CTGGTTTAGCATTTGGATTGGATCGGATAGCTATGTTACTAACTGGTTCTAAGAACATTCGGGAGGTGATTGCGTTTCCT
AAAACTACGGCATCAGTAGATATAATGGCAAATGCGCCTGATTAA

Upstream 100 bases:

>100_bases
ATGTATTTTGTAAGTTATAATATGCATGTGCTTAATTGATATGTAATTTTCTGTAAAATAGATATTATTCAATTCGATAT
TCATGATTAGAGGTATTCGT

Downstream 100 bases:

>100_bases
TTTATGTTATCAAGCAGAAGTGTTAATATTGTAGTATTTATGTGGGTAGATTTGTTTGGTATTAGAAAAATATTTAAGGA
GGTTATTGTAGATATTTTAA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MRTAYCGQLNLSHVGLEVTLCGWINKYRNFGGLIFIDLRDREGCIQVCFDVYQNKEVCISAAKLKQEFCIQLIGMVRARP
KNQINSNISTGAVEVVAKKFSILNISDPLPLDISKNNIEENRLKYRYLDLRRSIMFDRIKTRSRIMSIVHRFMELEGFLN
IETPMLTKVTPEGSRDYIVPSRLHAGKNYALPQSPQIFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFM
TTQKIRELMEIFIRIIWREILNVELGVFSQFTYSEVMQRFGSDAPDLRNPIEMFDVSYLFNSTQNRLSFIRANNIGVQAI
AMKVPNGRQLTQKQIDEYIYYSKQCGLKELLWVKVQFSDNDITKKEIQGSVTNFIDNLTLDIILNKTNIKSNDILFVGFN
DNKNQFITKMLSALRLKLGNDLCLIKKDSWAPLWIIDFPMFKKNCHGEYTSMHHMFTSPKNCDVQMLKKDPLLVISEAYD
MVINGCEIGSGSARIHSFDMQQAVFNILGITQNDQKKKFGYFMDALKYGAPPHAGLAFGLDRIAMLLTGSKNIREVIAFP
KTTASVDIMANAPD

Sequences:

>Translated_574_residues
MRTAYCGQLNLSHVGLEVTLCGWINKYRNFGGLIFIDLRDREGCIQVCFDVYQNKEVCISAAKLKQEFCIQLIGMVRARP
KNQINSNISTGAVEVVAKKFSILNISDPLPLDISKNNIEENRLKYRYLDLRRSIMFDRIKTRSRIMSIVHRFMELEGFLN
IETPMLTKVTPEGSRDYIVPSRLHAGKNYALPQSPQIFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFM
TTQKIRELMEIFIRIIWREILNVELGVFSQFTYSEVMQRFGSDAPDLRNPIEMFDVSYLFNSTQNRLSFIRANNIGVQAI
AMKVPNGRQLTQKQIDEYIYYSKQCGLKELLWVKVQFSDNDITKKEIQGSVTNFIDNLTLDIILNKTNIKSNDILFVGFN
DNKNQFITKMLSALRLKLGNDLCLIKKDSWAPLWIIDFPMFKKNCHGEYTSMHHMFTSPKNCDVQMLKKDPLLVISEAYD
MVINGCEIGSGSARIHSFDMQQAVFNILGITQNDQKKKFGYFMDALKYGAPPHAGLAFGLDRIAMLLTGSKNIREVIAFP
KTTASVDIMANAPD
>Mature_574_residues
MRTAYCGQLNLSHVGLEVTLCGWINKYRNFGGLIFIDLRDREGCIQVCFDVYQNKEVCISAAKLKQEFCIQLIGMVRARP
KNQINSNISTGAVEVVAKKFSILNISDPLPLDISKNNIEENRLKYRYLDLRRSIMFDRIKTRSRIMSIVHRFMELEGFLN
IETPMLTKVTPEGSRDYIVPSRLHAGKNYALPQSPQIFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFM
TTQKIRELMEIFIRIIWREILNVELGVFSQFTYSEVMQRFGSDAPDLRNPIEMFDVSYLFNSTQNRLSFIRANNIGVQAI
AMKVPNGRQLTQKQIDEYIYYSKQCGLKELLWVKVQFSDNDITKKEIQGSVTNFIDNLTLDIILNKTNIKSNDILFVGFN
DNKNQFITKMLSALRLKLGNDLCLIKKDSWAPLWIIDFPMFKKNCHGEYTSMHHMFTSPKNCDVQMLKKDPLLVISEAYD
MVINGCEIGSGSARIHSFDMQQAVFNILGITQNDQKKKFGYFMDALKYGAPPHAGLAFGLDRIAMLLTGSKNIREVIAFP
KTTASVDIMANAPD

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=598, Percent_Identity=38.4615384615385, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI45439306, Length=234, Percent_Identity=26.0683760683761, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI194272210, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI5031815, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1788173, Length=575, Percent_Identity=56.1739130434783, Blast_Score=671, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=278, Percent_Identity=26.978417266187, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789256, Length=287, Percent_Identity=26.8292682926829, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32566633, Length=596, Percent_Identity=32.8859060402685, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71994340, Length=136, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17535925, Length=136, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17535927, Length=136, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17551876, Length=274, Percent_Identity=24.8175182481752, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325153, Length=653, Percent_Identity=29.5558958652374, Blast_Score=240, Evalue=5e-64,
Organism=Saccharomyces cerevisiae, GI6323011, Length=306, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321807, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320242, Length=232, Percent_Identity=23.7068965517241, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584738, Length=591, Percent_Identity=34.3485617597293, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24640849, Length=251, Percent_Identity=24.3027888446215, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640851, Length=251, Percent_Identity=24.3027888446215, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_BLOPB (Q492L1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277962.1
- ProteinModelPortal:   Q492L1
- SMR:   Q492L1
- STRING:   Q492L1
- GeneID:   3562963
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_467
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- ProtClustDB:   PRK00476
- BioCyc:   CBLO291272:BPEN_467-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 66035; Mature: 66035

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAYCGQLNLSHVGLEVTLCGWINKYRNFGGLIFIDLRDREGCIQVCFDVYQNKEVCIS
CCCEEECCCCCEECCEEEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHH
AAKLKQEFCIQLIGMVRARPKNQINSNISTGAVEVVAKKFSILNISDPLPLDISKNNIEE
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCHH
NRLKYRYLDLRRSIMFDRIKTRSRIMSIVHRFMELEGFLNIETPMLTKVTPEGSRDYIVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCC
SRLHAGKNYALPQSPQIFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFM
HHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
TTQKIRELMEIFIRIIWREILNVELGVFSQFTYSEVMQRFGSDAPDLRNPIEMFDVSYLF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NSTQNRLSFIRANNIGVQAIAMKVPNGRQLTQKQIDEYIYYSKQCGLKELLWVKVQFSDN
HCCHHHEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC
DITKKEIQGSVTNFIDNLTLDIILNKTNIKSNDILFVGFNDNKNQFITKMLSALRLKLGN
CCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
DLCLIKKDSWAPLWIIDFPMFKKNCHGEYTSMHHMFTSPKNCDVQMLKKDPLLVISEAYD
CEEEEEECCCCCEEEEECCHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEECHHH
MVINGCEIGSGSARIHSFDMQQAVFNILGITQNDQKKKFGYFMDALKYGAPPHAGLAFGL
HHEECCEECCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
DRIAMLLTGSKNIREVIAFPKTTASVDIMANAPD
HHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRTAYCGQLNLSHVGLEVTLCGWINKYRNFGGLIFIDLRDREGCIQVCFDVYQNKEVCIS
CCCEEECCCCCEECCEEEEEHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHH
AAKLKQEFCIQLIGMVRARPKNQINSNISTGAVEVVAKKFSILNISDPLPLDISKNNIEE
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCHH
NRLKYRYLDLRRSIMFDRIKTRSRIMSIVHRFMELEGFLNIETPMLTKVTPEGSRDYIVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCCC
SRLHAGKNYALPQSPQIFKQLLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDIETSFM
HHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHH
TTQKIRELMEIFIRIIWREILNVELGVFSQFTYSEVMQRFGSDAPDLRNPIEMFDVSYLF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NSTQNRLSFIRANNIGVQAIAMKVPNGRQLTQKQIDEYIYYSKQCGLKELLWVKVQFSDN
HCCHHHEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC
DITKKEIQGSVTNFIDNLTLDIILNKTNIKSNDILFVGFNDNKNQFITKMLSALRLKLGN
CCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
DLCLIKKDSWAPLWIIDFPMFKKNCHGEYTSMHHMFTSPKNCDVQMLKKDPLLVISEAYD
CEEEEEECCCCCEEEEECCHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEECHHH
MVINGCEIGSGSARIHSFDMQQAVFNILGITQNDQKKKFGYFMDALKYGAPPHAGLAFGL
HHEECCEECCCCCEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHH
DRIAMLLTGSKNIREVIAFPKTTASVDIMANAPD
HHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA