Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 71892219

GI number: 71892219

Start: 542815

End: 544203

Strand: Direct

Name: pabB [H]

Synonym: BPEN_457

Alternate gene names: 71892219

Gene position: 542815-544203 (Clockwise)

Preceding gene: 71892217

Following gene: 71892221

Centisome position: 68.57

GC content: 31.17

Gene sequence:

>1389_bases
ATGGGCATGCATCTTATAGAATTACCCTATCACCCTTATACTGTACTGAATCTTTTTGATCCTTTATCTAATACCCCATG
GTCTATGTTATTGTATTCTGGTCATAATAATAAACACCCAGATAGTCGTTTTGATATATTAGTTACTCATCCAACTCTTA
CATTAACAACGCACAACAATATCACTACAATTTCTTATGATAAAAATCATCAAATTGATAATACAGACCCATTTATCTTA
CTAAAAAAATATATTCATATCATGAATATGAAACCAGAAAATAACTGTCAATTACCATTTCAAGGTGGATTTTTAGGTGT
ATTTGGATATGATCTCGCAAGATATATTGAATCAATGCCAAAATTAGCAGAACAAGACCTTTCGTTCCCAGATATGGCAA
TAGGTTTGTATCGCTGGGCGATCATTGCGGATCATAAACTTTGTAAAAATTATCTTGTTACTCACGACGATCCTAATCAA
ATATTGACCTGGGTATATACACAACAACATATATATAACAATCATGTTTCTAATACATCATTCAATCTCATACAACCATG
GAAAAGTAACATTAGTCGATCTGAATATAAGCAAAAATTCCATACTATCCAAAAACATATAATTTCAGGAAATTGCTATC
AAGTATGTCTTTCTCAACGTTTCTCTGCTCCATATATAGGAGATGAATGGATAGCATTTCGTTATCTGTTACATTATAAT
CACGCACCTTTTTCAGCTTTTGTTCGACTACCAAACAAATTAAGTATACTCAGTTTATCTCCAGAACGCTTTCTAAGGTT
ACATAATACAAAAATTAAAACTCAACCTATTAAAGGTACGTTACCTAGATTAAAAAACGCACAAGATGATTATCACCAAA
TTATTAAATTATCTAAATCTACAAAAAATCAATCAGAAAATTTAATGATTGTCGATTTATTAAGAAATGATATTGGAAAA
GTAGCTGTTCCGGGCAGTATTCATGTATCTAAATTATTTGATATTCGATCATTTCCAGGAGTACATCATATGATCAGTAC
CATTACAGGAGAACTTTCTAATAATTTTTCTGCTTGTGACTTATTACGTGCATGTTTTCCAGGAGGATCTATAATTGGAG
CCCCAAAAATTCAAGTTATGCAATTAATTGAACAACTTGAACCACAACGCCGGAACGTTTGGTCTGGAAGTATTGGATAC
TTAAGTTGTTGTGGCAATATGGATACCAATATTGCTATCAGAACAATATTAGCTGAAAGACAATATCTATTTTGTTCAGT
AGGAAGCGGTATTATTTTTGACAGCGATGAAGAAACAGAATATCAAGAAATGCAATACAAAATCTCTACTTTATTGCTAC
CACTACTAAAAAAATTTTATTTAAAATAA

Upstream 100 bases:

>100_bases
AATTTTAAATATTCTTCATTTTTAAAAAAAAATAACAATAAAATGTTATATGCATAATCAATATATATGCTTACAATCAT
AAAGGAAAAATCTGTTTTAA

Downstream 100 bases:

>100_bases
CTGCTTTAAATCAACAATTCATAGTATCACACATACATATGTGTATATGTAACAATACTATTTATTAATGCGTATCATTA
AAAAATAAAAGGCATTCTAT

Product: aminodeoxychorismate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MGMHLIELPYHPYTVLNLFDPLSNTPWSMLLYSGHNNKHPDSRFDILVTHPTLTLTTHNNITTISYDKNHQIDNTDPFIL
LKKYIHIMNMKPENNCQLPFQGGFLGVFGYDLARYIESMPKLAEQDLSFPDMAIGLYRWAIIADHKLCKNYLVTHDDPNQ
ILTWVYTQQHIYNNHVSNTSFNLIQPWKSNISRSEYKQKFHTIQKHIISGNCYQVCLSQRFSAPYIGDEWIAFRYLLHYN
HAPFSAFVRLPNKLSILSLSPERFLRLHNTKIKTQPIKGTLPRLKNAQDDYHQIIKLSKSTKNQSENLMIVDLLRNDIGK
VAVPGSIHVSKLFDIRSFPGVHHMISTITGELSNNFSACDLLRACFPGGSIIGAPKIQVMQLIEQLEPQRRNVWSGSIGY
LSCCGNMDTNIAIRTILAERQYLFCSVGSGIIFDSDEETEYQEMQYKISTLLLPLLKKFYLK

Sequences:

>Translated_462_residues
MGMHLIELPYHPYTVLNLFDPLSNTPWSMLLYSGHNNKHPDSRFDILVTHPTLTLTTHNNITTISYDKNHQIDNTDPFIL
LKKYIHIMNMKPENNCQLPFQGGFLGVFGYDLARYIESMPKLAEQDLSFPDMAIGLYRWAIIADHKLCKNYLVTHDDPNQ
ILTWVYTQQHIYNNHVSNTSFNLIQPWKSNISRSEYKQKFHTIQKHIISGNCYQVCLSQRFSAPYIGDEWIAFRYLLHYN
HAPFSAFVRLPNKLSILSLSPERFLRLHNTKIKTQPIKGTLPRLKNAQDDYHQIIKLSKSTKNQSENLMIVDLLRNDIGK
VAVPGSIHVSKLFDIRSFPGVHHMISTITGELSNNFSACDLLRACFPGGSIIGAPKIQVMQLIEQLEPQRRNVWSGSIGY
LSCCGNMDTNIAIRTILAERQYLFCSVGSGIIFDSDEETEYQEMQYKISTLLLPLLKKFYLK
>Mature_461_residues
GMHLIELPYHPYTVLNLFDPLSNTPWSMLLYSGHNNKHPDSRFDILVTHPTLTLTTHNNITTISYDKNHQIDNTDPFILL
KKYIHIMNMKPENNCQLPFQGGFLGVFGYDLARYIESMPKLAEQDLSFPDMAIGLYRWAIIADHKLCKNYLVTHDDPNQI
LTWVYTQQHIYNNHVSNTSFNLIQPWKSNISRSEYKQKFHTIQKHIISGNCYQVCLSQRFSAPYIGDEWIAFRYLLHYNH
APFSAFVRLPNKLSILSLSPERFLRLHNTKIKTQPIKGTLPRLKNAQDDYHQIIKLSKSTKNQSENLMIVDLLRNDIGKV
AVPGSIHVSKLFDIRSFPGVHHMISTITGELSNNFSACDLLRACFPGGSIIGAPKIQVMQLIEQLEPQRRNVWSGSIGYL
SCCGNMDTNIAIRTILAERQYLFCSVGSGIIFDSDEETEYQEMQYKISTLLLPLLKKFYLK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=439, Percent_Identity=51.9362186788155, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI1787518, Length=393, Percent_Identity=30.0254452926209, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786809, Length=225, Percent_Identity=22.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=395, Percent_Identity=30.126582278481, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6324361, Length=420, Percent_Identity=26.1904761904762, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 53216; Mature: 53085

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMHLIELPYHPYTVLNLFDPLSNTPWSMLLYSGHNNKHPDSRFDILVTHPTLTLTTHNN
CCCEEEECCCCCEEHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCEEEEEECCC
ITTISYDKNHQIDNTDPFILLKKYIHIMNMKPENNCQLPFQGGFLGVFGYDLARYIESMP
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
KLAEQDLSFPDMAIGLYRWAIIADHKLCKNYLVTHDDPNQILTWVYTQQHIYNNHVSNTS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCC
FNLIQPWKSNISRSEYKQKFHTIQKHIISGNCYQVCLSQRFSAPYIGDEWIAFRYLLHYN
CEEECCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
HAPFSAFVRLPNKLSILSLSPERFLRLHNTKIKTQPIKGTLPRLKNAQDDYHQIIKLSKS
CCCHHHHHCCCCCEEEEEECHHHHHHHHCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHH
TKNQSENLMIVDLLRNDIGKVAVPGSIHVSKLFDIRSFPGVHHMISTITGELSNNFSACD
CCCCCCCEEEEEEHHHCCCCEECCCCEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
LLRACFPGGSIIGAPKIQVMQLIEQLEPQRRNVWSGSIGYLSCCGNMDTNIAIRTILAER
HHHHHCCCCCEECCCHHHHHHHHHHHCHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHCC
QYLFCSVGSGIIFDSDEETEYQEMQYKISTLLLPLLKKFYLK
CEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GMHLIELPYHPYTVLNLFDPLSNTPWSMLLYSGHNNKHPDSRFDILVTHPTLTLTTHNN
CCEEEECCCCCEEHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCEEEEEECCC
ITTISYDKNHQIDNTDPFILLKKYIHIMNMKPENNCQLPFQGGFLGVFGYDLARYIESMP
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
KLAEQDLSFPDMAIGLYRWAIIADHKLCKNYLVTHDDPNQILTWVYTQQHIYNNHVSNTS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHCCCCCCCC
FNLIQPWKSNISRSEYKQKFHTIQKHIISGNCYQVCLSQRFSAPYIGDEWIAFRYLLHYN
CEEECCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
HAPFSAFVRLPNKLSILSLSPERFLRLHNTKIKTQPIKGTLPRLKNAQDDYHQIIKLSKS
CCCHHHHHCCCCCEEEEEECHHHHHHHHCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHH
TKNQSENLMIVDLLRNDIGKVAVPGSIHVSKLFDIRSFPGVHHMISTITGELSNNFSACD
CCCCCCCEEEEEEHHHCCCCEECCCCEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHH
LLRACFPGGSIIGAPKIQVMQLIEQLEPQRRNVWSGSIGYLSCCGNMDTNIAIRTILAER
HHHHHCCCCCEECCCHHHHHHHHHHHCHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHCC
QYLFCSVGSGIIFDSDEETEYQEMQYKISTLLLPLLKKFYLK
CEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]