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The map label for this gene is trpG [H]

Identifier: 71892201

GI number: 71892201

Start: 520406

End: 521002

Strand: Direct

Name: trpG [H]

Synonym: BPEN_439

Alternate gene names: 71892201

Gene position: 520406-521002 (Clockwise)

Preceding gene: 71892200

Following gene: 71892202

Centisome position: 65.74

GC content: 34.17

Gene sequence:

>597_bases
ATGGTTAATGTAATATTACTAGATAACATTGACTCATTTACGTATAATTTAGTAGATCAGTTACGCAATCACGGCCATCA
AGTACTAATATATACTAATCAACTACCTGCATCGATCATTATTGATACCATATCGAATATGGTAAACCCAATTTTAATGT
TATCGCCAGGTCCTGGATCCCCTAGTAAAGCTGGATGCATGACAAAATTGATAGCACAATTACATAGAAAAATTCCAATC
ATTGGGATCTGTCTGGGATATCAAGCCATTGTAGAATTTTATGGAGGGAACATATCGCGATCAAAAGAAATTTTTCATGG
AAAATCTTCTTTGATACATCACGACAATTCAGCTATGTTTTCTAATATACCAAACCCTTTTTTAGTAGGACGATACCATT
CATTAATAGGTAGTTCTATACCAAATAATTTAAAAATTAATGCTTATTACAATAAACACACAGCAATGGCAGTACGTAAT
GACTCTGATCGGATTTGCGGGTTTCAATTTCATCCCGAATCTATCTTAACTGCTCATGGAACACGACTTATTCAGCAAAC
TATCGCATGGGCAATATGCTTAGACAAGGAACAATAA

Upstream 100 bases:

>100_bases
ATTCCATACCTCAATCAGAAGCTGATGAAAGCCGTAGCAAAGCGCGCGCTGTTTTACATGCCATTTCTACAGCACATGGT
TCTAAGGAGTTATTTTAACA

Downstream 100 bases:

>100_bases
CATGCAAAAAATCTTAGACACCTTATATCAAGGTAAAAATATTAACCAAAAACAAAGTGAAGCATTATTACATTCCATAA
TAAAAGAAAAATTATCCGCA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MVNVILLDNIDSFTYNLVDQLRNHGHQVLIYTNQLPASIIIDTISNMVNPILMLSPGPGSPSKAGCMTKLIAQLHRKIPI
IGICLGYQAIVEFYGGNISRSKEIFHGKSSLIHHDNSAMFSNIPNPFLVGRYHSLIGSSIPNNLKINAYYNKHTAMAVRN
DSDRICGFQFHPESILTAHGTRLIQQTIAWAICLDKEQ

Sequences:

>Translated_198_residues
MVNVILLDNIDSFTYNLVDQLRNHGHQVLIYTNQLPASIIIDTISNMVNPILMLSPGPGSPSKAGCMTKLIAQLHRKIPI
IGICLGYQAIVEFYGGNISRSKEIFHGKSSLIHHDNSAMFSNIPNPFLVGRYHSLIGSSIPNNLKINAYYNKHTAMAVRN
DSDRICGFQFHPESILTAHGTRLIQQTIAWAICLDKEQ
>Mature_198_residues
MVNVILLDNIDSFTYNLVDQLRNHGHQVLIYTNQLPASIIIDTISNMVNPILMLSPGPGSPSKAGCMTKLIAQLHRKIPI
IGICLGYQAIVEFYGGNISRSKEIFHGKSSLIHHDNSAMFSNIPNPFLVGRYHSLIGSSIPNNLKINAYYNKHTAMAVRN
DSDRICGFQFHPESILTAHGTRLIQQTIAWAICLDKEQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=61.7801047120419, Blast_Score=265, Evalue=1e-72,
Organism=Escherichia coli, GI1789760, Length=183, Percent_Identity=34.9726775956284, Blast_Score=130, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=41.0810810810811, Blast_Score=142, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324361, Length=208, Percent_Identity=25.9615384615385, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 22039; Mature: 22039

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVILLDNIDSFTYNLVDQLRNHGHQVLIYTNQLPASIIIDTISNMVNPILMLSPGPGS
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCC
PSKAGCMTKLIAQLHRKIPIIGICLGYQAIVEFYGGNISRSKEIFHGKSSLIHHDNSAMF
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCHHH
SNIPNPFLVGRYHSLIGSSIPNNLKINAYYNKHTAMAVRNDSDRICGFQFHPESILTAHG
HCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCCEEEEEECCHHHHHHHH
TRLIQQTIAWAICLDKEQ
HHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MVNVILLDNIDSFTYNLVDQLRNHGHQVLIYTNQLPASIIIDTISNMVNPILMLSPGPGS
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCC
PSKAGCMTKLIAQLHRKIPIIGICLGYQAIVEFYGGNISRSKEIFHGKSSLIHHDNSAMF
CCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCCCHHH
SNIPNPFLVGRYHSLIGSSIPNNLKINAYYNKHTAMAVRNDSDRICGFQFHPESILTAHG
HCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCCEEEEEECCHHHHHHHH
TRLIQQTIAWAICLDKEQ
HHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7038627; 6283099; 9097039; 9278503; 4594441 [H]