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The map label for this gene is fabH

Identifier: 71892185

GI number: 71892185

Start: 493709

End: 494662

Strand: Reverse

Name: fabH

Synonym: BPEN_418

Alternate gene names: 71892185

Gene position: 494662-493709 (Counterclockwise)

Preceding gene: 71892186

Following gene: 71892184

Centisome position: 62.48

GC content: 37.21

Gene sequence:

>954_bases
ATGTTTACTAGAATTCTTGGAACAGGGAGTTACTTACCTAAAAACATTAGATCTAATATTGTTTTAGAAAAAATGGTAGA
TACATCGCATGAATGGATTGTTGCCCGTACTGGTATTCAAGAACGGCGTATTTCTACTTCTGATGAAACTGTTGCCAAAA
TGGGTTATTTTGCTGCTAAAAGAGCTTTAGATATGTCTTGTGTGCACTCTGATAAAGTAGGGATTATTATTGTTGCAACT
ACATCTTCCAGTCATGCATTTCCTAGTTCAGCATGTCAAATTCAACGTGACCTACATATACGAGATACTATTGCCTTCGA
CTTATCAGCAGCTTGTTCTGGATTTGTTTATGCACTAGGTGTAGCGGATCAATATGTTAAAAATGGAAGCGTAGATTATG
CTTTGGTTGTAGGGTCAGATACTTTAAGTCATGCTCTAAATCCTAGAGACCGTGGAACATTGATTTTATTTGGGGATGGA
GCAGGTGCAGTAGTACTTGGTCGCTCGAAAACACCGGGTATTATTTCTATTCACTTACATGCAGATGGAGATCATGGGGA
TTTATTGACTCTTCCTAATTGTAATAGAAAGAGTCCTGCTATATCTAATTATTTAACCATGTCTGGCAACAAAGTATTTA
AAATAGCTGTTTCTGTTTTAGCACGCGTTATCGATGAGACTTTGAATGTTAATAATTTACATCGAGATGAATTAGATTGG
TTAGTCCCTCATCAGGCTAATTTAAGAATTATTTCTGCTACTGCTAAACGATTAGATATGGATATGAGAAAAGTAGTAAT
TACGCTTGACAGACATGGGAATACATCTGCAGCTTCTGTTCCTTTAGCGCTAGATGAAGCTGTACGTGATGGTCGTATTA
AGTCAGGTCAACTAGTATTATTAGAAGCGTTTGGGGCTGGATTTACCTGGGGTTCAGCGTTGTTACGATTTTAA

Upstream 100 bases:

>100_bases
CCGCTATTACACAAGCAATGCATTCCGTGGAACGGGAGGTTCCAGAAAAAATTTCTCATCAATTAAGTACAGTGTTATCT
AAAAATAATCATTAATATAC

Downstream 100 bases:

>100_bases
TTACGAAAGGAATATTAATTATTATGAATACATTAGCTGTGGTATTTCCAGGACAGGCAGCTCAAAAAGTAGGGATGCTA
AGAACTCTTGCGGAACATTA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MFTRILGTGSYLPKNIRSNIVLEKMVDTSHEWIVARTGIQERRISTSDETVAKMGYFAAKRALDMSCVHSDKVGIIIVAT
TSSSHAFPSSACQIQRDLHIRDTIAFDLSAACSGFVYALGVADQYVKNGSVDYALVVGSDTLSHALNPRDRGTLILFGDG
AGAVVLGRSKTPGIISIHLHADGDHGDLLTLPNCNRKSPAISNYLTMSGNKVFKIAVSVLARVIDETLNVNNLHRDELDW
LVPHQANLRIISATAKRLDMDMRKVVITLDRHGNTSAASVPLALDEAVRDGRIKSGQLVLLEAFGAGFTWGSALLRF

Sequences:

>Translated_317_residues
MFTRILGTGSYLPKNIRSNIVLEKMVDTSHEWIVARTGIQERRISTSDETVAKMGYFAAKRALDMSCVHSDKVGIIIVAT
TSSSHAFPSSACQIQRDLHIRDTIAFDLSAACSGFVYALGVADQYVKNGSVDYALVVGSDTLSHALNPRDRGTLILFGDG
AGAVVLGRSKTPGIISIHLHADGDHGDLLTLPNCNRKSPAISNYLTMSGNKVFKIAVSVLARVIDETLNVNNLHRDELDW
LVPHQANLRIISATAKRLDMDMRKVVITLDRHGNTSAASVPLALDEAVRDGRIKSGQLVLLEAFGAGFTWGSALLRF
>Mature_317_residues
MFTRILGTGSYLPKNIRSNIVLEKMVDTSHEWIVARTGIQERRISTSDETVAKMGYFAAKRALDMSCVHSDKVGIIIVAT
TSSSHAFPSSACQIQRDLHIRDTIAFDLSAACSGFVYALGVADQYVKNGSVDYALVVGSDTLSHALNPRDRGTLILFGDG
AGAVVLGRSKTPGIISIHLHADGDHGDLLTLPNCNRKSPAISNYLTMSGNKVFKIAVSVLARVIDETLNVNNLHRDELDW
LVPHQANLRIISATAKRLDMDMRKVVITLDRHGNTSAASVPLALDEAVRDGRIKSGQLVLLEAFGAGFTWGSALLRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=68.4542586750789, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_BLOPB (Q492Q4)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277917.1
- ProteinModelPortal:   Q492Q4
- SMR:   Q492Q4
- STRING:   Q492Q4
- GeneID:   3562693
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_418
- eggNOG:   COG0332
- HOGENOM:   HBG649927
- OMA:   YLPAQVR
- ProtClustDB:   PRK09352
- BioCyc:   CBLO291272:BPEN_418-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 34369; Mature: 34369

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: ACT_SITE 112-112 ACT_SITE 244-244 ACT_SITE 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTRILGTGSYLPKNIRSNIVLEKMVDTSHEWIVARTGIQERRISTSDETVAKMGYFAAK
CCEEEECCCCCCCCHHHHCEEHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHH
RALDMSCVHSDKVGIIIVATTSSSHAFPSSACQIQRDLHIRDTIAFDLSAACSGFVYALG
HHHCCEEEECCCEEEEEEEECCCCCCCCCHHHHHHHCCEEEEEEEEEHHHHHCCEEEEEH
VADQYVKNGSVDYALVVGSDTLSHALNPRDRGTLILFGDGAGAVVLGRSKTPGIISIHLH
HHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGDHGDLLTLPNCNRKSPAISNYLTMSGNKVFKIAVSVLARVIDETLNVNNLHRDELDW
ECCCCCCEEECCCCCCCCCCCCCEEEECCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LVPHQANLRIISATAKRLDMDMRKVVITLDRHGNTSAASVPLALDEAVRDGRIKSGQLVL
ECCCCCCEEEEEEHHHHHCCCCEEEEEEEECCCCCCCCCCCEEHHHHHHCCCCCCCCEEE
LEAFGAGFTWGSALLRF
EEECCCCCHHHHHHHCC
>Mature Secondary Structure
MFTRILGTGSYLPKNIRSNIVLEKMVDTSHEWIVARTGIQERRISTSDETVAKMGYFAAK
CCEEEECCCCCCCCHHHHCEEHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHH
RALDMSCVHSDKVGIIIVATTSSSHAFPSSACQIQRDLHIRDTIAFDLSAACSGFVYALG
HHHCCEEEECCCEEEEEEEECCCCCCCCCHHHHHHHCCEEEEEEEEEHHHHHCCEEEEEH
VADQYVKNGSVDYALVVGSDTLSHALNPRDRGTLILFGDGAGAVVLGRSKTPGIISIHLH
HHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGDHGDLLTLPNCNRKSPAISNYLTMSGNKVFKIAVSVLARVIDETLNVNNLHRDELDW
ECCCCCCEEECCCCCCCCCCCCCEEEECCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCE
LVPHQANLRIISATAKRLDMDMRKVVITLDRHGNTSAASVPLALDEAVRDGRIKSGQLVL
ECCCCCCEEEEEEHHHHHCCCCEEEEEEEECCCCCCCCCCCEEHHHHHHCCCCCCCCEEE
LEAFGAGFTWGSALLRF
EEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA