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The map label for this gene is fabD [H]

Identifier: 71892184

GI number: 71892184

Start: 492744

End: 493685

Strand: Reverse

Name: fabD [H]

Synonym: BPEN_417

Alternate gene names: 71892184

Gene position: 493685-492744 (Counterclockwise)

Preceding gene: 71892185

Following gene: 71892183

Centisome position: 62.36

GC content: 36.73

Gene sequence:

>942_bases
ATGAATACATTAGCTGTGGTATTTCCAGGACAGGCAGCTCAAAAAGTAGGGATGCTAAGAACTCTTGCGGAACATTATCC
GCTAGTAAAAGAGACTTTTTCTGAAGTATCGGAAGTTCTAGGTTATGATATATGGAAATTGGTACAGCGTGGACCTGTTA
CAGAATTAAATAAAACTTATCGAGCGCAGCCGGCTATTTTAACAGCTTCAGTAGCTGTTTGGAGAATATGGAAACAGCAG
GGAGGTTGTACACCAAAGATAATGGCTGGTCATAGCTTAGGAGAGTATTCTGCTTTAGTATGTGCGGAAGGTATGGATTT
GTATTCTGCAGTTAAATTAGTAATGATACGTGGTATGTTAATGCAAGAAGTAGTACCGTATGGACGTGGAGCTATGTCTG
TAATTATCGGGCTAAGTAATGACGTTGTTTTTGAATTATGTAACAAAGCAGCACAACAAGATCAAATTGTTTCTCCTGCT
AGTTTTAATGGGCCTGGACACGTGGTTATTTCCGGACATAAAGAAGCAGTAAATCGTGTCAATTTGTGTTGTAAAAATGC
AGGCGCAAAACATATACTTATGCTGCCGATTAGTGTTCCATCACATTGCTCATTAATGAAACCAGCAGTTGTAAAATTCA
GAAAAGAATTAGAAAAAATCGTCATCACTACTCCTAGTATACCAGTAGTAAATAATGTTGATGCGTGTGTTAAGTGGGAA
TCTAAAGATATTCGTAATGCATTAATACGGCAATTATATACTCCGGTGCGTTGGCATGAAATCGTGCAATATTGCATTCA
TCAAAAAATTAAGAGATTTTTAGAAATGGGACCTGGAAAAATATTAACTGGACTGATACGTAGTACTGTTAGTGATGTGT
TTAGTTTATCAGTAAATGATCCTGTTTCTTTATCAGAAGCAATTAGAATGAATAAGAGTTAA

Upstream 100 bases:

>100_bases
TTAAGTCAGGTCAACTAGTATTATTAGAAGCGTTTGGGGCTGGATTTACCTGGGGTTCAGCGTTGTTACGATTTTAATTA
CGAAAGGAATATTAATTATT

Downstream 100 bases:

>100_bases
TATATTTGTATAAGAGGAGTACATGTAGGATGAATTTTAATGGAAAAATTGTTTTAGTAACTGGTGCTCGTCGCGGTATT
GGTCGTGCTATTATCGAAAT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNTLAVVFPGQAAQKVGMLRTLAEHYPLVKETFSEVSEVLGYDIWKLVQRGPVTELNKTYRAQPAILTASVAVWRIWKQQ
GGCTPKIMAGHSLGEYSALVCAEGMDLYSAVKLVMIRGMLMQEVVPYGRGAMSVIIGLSNDVVFELCNKAAQQDQIVSPA
SFNGPGHVVISGHKEAVNRVNLCCKNAGAKHILMLPISVPSHCSLMKPAVVKFRKELEKIVITTPSIPVVNNVDACVKWE
SKDIRNALIRQLYTPVRWHEIVQYCIHQKIKRFLEMGPGKILTGLIRSTVSDVFSLSVNDPVSLSEAIRMNKS

Sequences:

>Translated_313_residues
MNTLAVVFPGQAAQKVGMLRTLAEHYPLVKETFSEVSEVLGYDIWKLVQRGPVTELNKTYRAQPAILTASVAVWRIWKQQ
GGCTPKIMAGHSLGEYSALVCAEGMDLYSAVKLVMIRGMLMQEVVPYGRGAMSVIIGLSNDVVFELCNKAAQQDQIVSPA
SFNGPGHVVISGHKEAVNRVNLCCKNAGAKHILMLPISVPSHCSLMKPAVVKFRKELEKIVITTPSIPVVNNVDACVKWE
SKDIRNALIRQLYTPVRWHEIVQYCIHQKIKRFLEMGPGKILTGLIRSTVSDVFSLSVNDPVSLSEAIRMNKS
>Mature_313_residues
MNTLAVVFPGQAAQKVGMLRTLAEHYPLVKETFSEVSEVLGYDIWKLVQRGPVTELNKTYRAQPAILTASVAVWRIWKQQ
GGCTPKIMAGHSLGEYSALVCAEGMDLYSAVKLVMIRGMLMQEVVPYGRGAMSVIIGLSNDVVFELCNKAAQQDQIVSPA
SFNGPGHVVISGHKEAVNRVNLCCKNAGAKHILMLPISVPSHCSLMKPAVVKFRKELEKIVITTPSIPVVNNVDACVKWE
SKDIRNALIRQLYTPVRWHEIVQYCIHQKIKRFLEMGPGKILTGLIRSTVSDVFSLSVNDPVSLSEAIRMNKS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=32.4414715719064, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=40.3669724770642, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787334, Length=310, Percent_Identity=53.8709677419355, Blast_Score=340, Evalue=6e-95,
Organism=Caenorhabditis elegans, GI71984332, Length=311, Percent_Identity=30.8681672025724, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24665753, Length=315, Percent_Identity=30.1587301587302, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34554; Mature: 34554

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLAVVFPGQAAQKVGMLRTLAEHYPLVKETFSEVSEVLGYDIWKLVQRGPVTELNKTY
CCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RAQPAILTASVAVWRIWKQQGGCTPKIMAGHSLGEYSALVCAEGMDLYSAVKLVMIRGML
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
MQEVVPYGRGAMSVIIGLSNDVVFELCNKAAQQDQIVSPASFNGPGHVVISGHKEAVNRV
HHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHH
NLCCKNAGAKHILMLPISVPSHCSLMKPAVVKFRKELEKIVITTPSIPVVNNVDACVKWE
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHEEEC
SKDIRNALIRQLYTPVRWHEIVQYCIHQKIKRFLEMGPGKILTGLIRSTVSDVFSLSVND
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
PVSLSEAIRMNKS
CCCHHHHHHCCCC
>Mature Secondary Structure
MNTLAVVFPGQAAQKVGMLRTLAEHYPLVKETFSEVSEVLGYDIWKLVQRGPVTELNKTY
CCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RAQPAILTASVAVWRIWKQQGGCTPKIMAGHSLGEYSALVCAEGMDLYSAVKLVMIRGML
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
MQEVVPYGRGAMSVIIGLSNDVVFELCNKAAQQDQIVSPASFNGPGHVVISGHKEAVNRV
HHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHH
NLCCKNAGAKHILMLPISVPSHCSLMKPAVVKFRKELEKIVITTPSIPVVNNVDACVKWE
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHEEEC
SKDIRNALIRQLYTPVRWHEIVQYCIHQKIKRFLEMGPGKILTGLIRSTVSDVFSLSVND
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
PVSLSEAIRMNKS
CCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]