Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 71892181

GI number: 71892181

Start: 490159

End: 490980

Strand: Reverse

Name: pabC [H]

Synonym: BPEN_414

Alternate gene names: 71892181

Gene position: 490980-490159 (Counterclockwise)

Preceding gene: 71892182

Following gene: 71892180

Centisome position: 62.02

GC content: 31.14

Gene sequence:

>822_bases
ATGTATTGGGTGAATGGAATTTCAAAAAGAACAATATCATTAAATAATCGTGCTTTGCATTTTGGAGATGGATTTTTTAC
GACTGCTAAAGTACAGAATGGAAAAATTGATTTTTTAGATTGGCATATGGATAGATTGGTTATTTCAGCGAAAAGGTTAA
TATTTAAAAATTTTAATTTTAATCTTCTGTATAAAGAAATGCAGCAAGCAGCTGCATATAGTGATATATATAGTGTGATT
AAAGTAATAATAAGTAGGAGTAATAGCCACAGACTATATGGATATCGATGCAGTAATGATATTGAACCATTACGTATAAT
TCATGTTAGTCGATTGCCAAAATATTACACGCGCTGGATTCATTCTGGGATTCGTTTAAGAACGAGTATTGTTCGGTTAG
CACGTAATGCTTGCTTGGCAGGAATAAAGCATCTTAATAGATTAGAACAAGTTATGATTGCCATTTGGGTAAGCAAAAGC
GAAACTGATGAAGCATTAGTTTTAGACACTGATGGAAACGTGGTAGAATGTTGTAGTGCCAACATTTTTTGGAGATATAA
ATATCAGGTATTTACTCCGTCTTTATATTATTCTGGTGTTAATGGAATTATGCGTCAACTGGTATTAAAATTATTACCAA
AATTAGGGTACTGTATACGAGAAGTGACGGTTGGACCTGAACATTTAAAAAATGCAAATGAAGTTTTTATTACAAATGCT
TTATTACCGTTAGCGTCAGTTAATTCAATTGATGATTTTGTGTATTCGGATAGGACATTATTTCATTTGCTACGTTTTCA
TATTATACATAATAAAATTTAA

Upstream 100 bases:

>100_bases
TATAAATTCTTTTATTACATATGATCATTAAAAATTGTTTTAGTATTAATTATATTAAATAATTATTAACATAATTAAAC
ACTGACTGATTGAGATTAAA

Downstream 100 bases:

>100_bases
AATATTTACAGTGTTGTTTAACATAATATATATAAAATATTTATGCTCTCTGTTAGTTATAATTATGTATTGTATTGATT
TATTTAAAAGTAACTAATGA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MYWVNGISKRTISLNNRALHFGDGFFTTAKVQNGKIDFLDWHMDRLVISAKRLIFKNFNFNLLYKEMQQAAAYSDIYSVI
KVIISRSNSHRLYGYRCSNDIEPLRIIHVSRLPKYYTRWIHSGIRLRTSIVRLARNACLAGIKHLNRLEQVMIAIWVSKS
ETDEALVLDTDGNVVECCSANIFWRYKYQVFTPSLYYSGVNGIMRQLVLKLLPKLGYCIREVTVGPEHLKNANEVFITNA
LLPLASVNSIDDFVYSDRTLFHLLRFHIIHNKI

Sequences:

>Translated_273_residues
MYWVNGISKRTISLNNRALHFGDGFFTTAKVQNGKIDFLDWHMDRLVISAKRLIFKNFNFNLLYKEMQQAAAYSDIYSVI
KVIISRSNSHRLYGYRCSNDIEPLRIIHVSRLPKYYTRWIHSGIRLRTSIVRLARNACLAGIKHLNRLEQVMIAIWVSKS
ETDEALVLDTDGNVVECCSANIFWRYKYQVFTPSLYYSGVNGIMRQLVLKLLPKLGYCIREVTVGPEHLKNANEVFITNA
LLPLASVNSIDDFVYSDRTLFHLLRFHIIHNKI
>Mature_273_residues
MYWVNGISKRTISLNNRALHFGDGFFTTAKVQNGKIDFLDWHMDRLVISAKRLIFKNFNFNLLYKEMQQAAAYSDIYSVI
KVIISRSNSHRLYGYRCSNDIEPLRIIHVSRLPKYYTRWIHSGIRLRTSIVRLARNACLAGIKHLNRLEQVMIAIWVSKS
ETDEALVLDTDGNVVECCSANIFWRYKYQVFTPSLYYSGVNGIMRQLVLKLLPKLGYCIREVTVGPEHLKNANEVFITNA
LLPLASVNSIDDFVYSDRTLFHLLRFHIIHNKI

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=264, Percent_Identity=43.1818181818182, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 31723; Mature: 31723

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWVNGISKRTISLNNRALHFGDGFFTTAKVQNGKIDFLDWHMDRLVISAKRLIFKNFNF
CCCCCCCCEEEEEECCCEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCC
NLLYKEMQQAAAYSDIYSVIKVIISRSNSHRLYGYRCSNDIEPLRIIHVSRLPKYYTRWI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHCHHHHHHHH
HSGIRLRTSIVRLARNACLAGIKHLNRLEQVMIAIWVSKSETDEALVLDTDGNVVECCSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCEEEEECC
NIFWRYKYQVFTPSLYYSGVNGIMRQLVLKLLPKLGYCIREVTVGPEHLKNANEVFITNA
CEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEH
LLPLASVNSIDDFVYSDRTLFHLLRFHIIHNKI
HHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYWVNGISKRTISLNNRALHFGDGFFTTAKVQNGKIDFLDWHMDRLVISAKRLIFKNFNF
CCCCCCCCEEEEEECCCEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCC
NLLYKEMQQAAAYSDIYSVIKVIISRSNSHRLYGYRCSNDIEPLRIIHVSRLPKYYTRWI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHCHHHHHHHH
HSGIRLRTSIVRLARNACLAGIKHLNRLEQVMIAIWVSKSETDEALVLDTDGNVVECCSA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCEEEEECC
NIFWRYKYQVFTPSLYYSGVNGIMRQLVLKLLPKLGYCIREVTVGPEHLKNANEVFITNA
CEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEH
LLPLASVNSIDDFVYSDRTLFHLLRFHIIHNKI
HHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]