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The map label for this gene is ycfH [H]

Identifier: 71892178

GI number: 71892178

Start: 487339

End: 488124

Strand: Reverse

Name: ycfH [H]

Synonym: BPEN_411

Alternate gene names: 71892178

Gene position: 488124-487339 (Counterclockwise)

Preceding gene: 71892179

Following gene: 71892177

Centisome position: 61.66

GC content: 31.55

Gene sequence:

>786_bases
ATGTTTTTGGTGGATTCCCATTGTCATTTAAATCAACTGAATTATCAAGATGTTCACAAAAATGTTTCAGATGTGTTGAA
CAAAGCTAAACAAAAGGGGGTTCAATTAGTCTTGTCGGTCAGCCTTACTATGTCAGATTATGAAGATATGGTAAAATTAA
TTGGATATAGAAGTGATGTTCTGTTTTCTTGTGGAGTGCATCCTACATATGTATATAATATTAATAATTTTGACAGCGAA
AAATTGTATGTTTTGTCTTCTAAAAGGAATGTAGTAGCTATCGGTGAAACTGGATTAGATTATTATCATCGATTAGAATC
AGATAGTAAAAAAAAGCAAAAAAAAGCATTTAGAGAACATATTCGTGTTGCTAAAGCAGCAAAAAAGCCAATTATTGTAC
ATAGTCGCGATTCTTGCAAGGATACTGTCACGCTTTTACGATCAGAAGAAGCGGAGGAGTGCGGTGGTATATTGCATTGT
TTTAGTGAAGATATAGATACTGCAAGATTATTGTTAGATCTTAATTTTTATATATCTTTTTCTGGAATGATAACATTTAC
TAAATCTTATATGATGCAAGAAGTAATTAAATATATACCTTCCGACCGTATTTTGTTAGAAACTGATTCTCCTTACCTCA
CCCCAGTTCCTTATAGAGGACAAGAGAATCAACCTGCTTACATATATGAAATTGCCAAATATGTAGCGTCTATAAAAAAT
ATAAATATAGATGAATTAGCGGTTATCACTACATCTAATTTTCGTACCTTGTTTCATTTGGAATAA

Upstream 100 bases:

>100_bases
TTTACTAATATTGATCGCGAATTATTATTGACTTATCGATTATTAAATTGGCAACAAGATATTGTTGAATCTTGTTTGCA
TTAATGGAGTGTATAATGTT

Downstream 100 bases:

>100_bases
AATTATAATAATATTATGTATTAATTTGTATGTATAAGTAAATTATTGTTCGTATTATTATTAATTTTTAGAGCATGGTA
ATTATACTGGTGCTGGATTA

Product: putative metallo-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFLVDSHCHLNQLNYQDVHKNVSDVLNKAKQKGVQLVLSVSLTMSDYEDMVKLIGYRSDVLFSCGVHPTYVYNINNFDSE
KLYVLSSKRNVVAIGETGLDYYHRLESDSKKKQKKAFREHIRVAKAAKKPIIVHSRDSCKDTVTLLRSEEAEECGGILHC
FSEDIDTARLLLDLNFYISFSGMITFTKSYMMQEVIKYIPSDRILLETDSPYLTPVPYRGQENQPAYIYEIAKYVASIKN
INIDELAVITTSNFRTLFHLE

Sequences:

>Translated_261_residues
MFLVDSHCHLNQLNYQDVHKNVSDVLNKAKQKGVQLVLSVSLTMSDYEDMVKLIGYRSDVLFSCGVHPTYVYNINNFDSE
KLYVLSSKRNVVAIGETGLDYYHRLESDSKKKQKKAFREHIRVAKAAKKPIIVHSRDSCKDTVTLLRSEEAEECGGILHC
FSEDIDTARLLLDLNFYISFSGMITFTKSYMMQEVIKYIPSDRILLETDSPYLTPVPYRGQENQPAYIYEIAKYVASIKN
INIDELAVITTSNFRTLFHLE
>Mature_261_residues
MFLVDSHCHLNQLNYQDVHKNVSDVLNKAKQKGVQLVLSVSLTMSDYEDMVKLIGYRSDVLFSCGVHPTYVYNINNFDSE
KLYVLSSKRNVVAIGETGLDYYHRLESDSKKKQKKAFREHIRVAKAAKKPIIVHSRDSCKDTVTLLRSEEAEECGGILHC
FSEDIDTARLLLDLNFYISFSGMITFTKSYMMQEVIKYIPSDRILLETDSPYLTPVPYRGQENQPAYIYEIAKYVASIKN
INIDELAVITTSNFRTLFHLE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=30.3370786516854, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=30.7116104868914, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=30.1470588235294, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=27.6515151515151, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI225903439, Length=232, Percent_Identity=28.0172413793103, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=28.82096069869, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI225903424, Length=273, Percent_Identity=23.8095238095238, Blast_Score=85, Evalue=5e-17,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=50.381679389313, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI48994985, Length=247, Percent_Identity=28.3400809716599, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI87082439, Length=260, Percent_Identity=24.6153846153846, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559024, Length=286, Percent_Identity=26.5734265734266, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=241, Percent_Identity=31.1203319502075, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=309, Percent_Identity=26.2135922330097, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=284, Percent_Identity=26.4084507042254, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221330018, Length=284, Percent_Identity=26.4084507042254, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24648690, Length=294, Percent_Identity=25.1700680272109, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29988; Mature: 29988

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVDSHCHLNQLNYQDVHKNVSDVLNKAKQKGVQLVLSVSLTMSDYEDMVKLIGYRSDV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEHHHHHHHHHHHCCCCCE
LFSCGVHPTYVYNINNFDSEKLYVLSSKRNVVAIGETGLDYYHRLESDSKKKQKKAFREH
EEECCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHH
IRVAKAAKKPIIVHSRDSCKDTVTLLRSEEAEECGGILHCFSEDIDTARLLLDLNFYISF
HHHHHHHCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEE
SGMITFTKSYMMQEVIKYIPSDRILLETDSPYLTPVPYRGQENQPAYIYEIAKYVASIKN
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCC
INIDELAVITTSNFRTLFHLE
CCCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MFLVDSHCHLNQLNYQDVHKNVSDVLNKAKQKGVQLVLSVSLTMSDYEDMVKLIGYRSDV
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEHHHHHHHHHHHCCCCCE
LFSCGVHPTYVYNINNFDSEKLYVLSSKRNVVAIGETGLDYYHRLESDSKKKQKKAFREH
EEECCCCCEEEEECCCCCCCEEEEEECCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHH
IRVAKAAKKPIIVHSRDSCKDTVTLLRSEEAEECGGILHCFSEDIDTARLLLDLNFYISF
HHHHHHHCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEE
SGMITFTKSYMMQEVIKYIPSDRILLETDSPYLTPVPYRGQENQPAYIYEIAKYVASIKN
CCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCC
INIDELAVITTSNFRTLFHLE
CCCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]