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The map label for this gene is sufS [H]

Identifier: 71892141

GI number: 71892141

Start: 441331

End: 442557

Strand: Direct

Name: sufS [H]

Synonym: BPEN_373

Alternate gene names: 71892141

Gene position: 441331-442557 (Clockwise)

Preceding gene: 71892140

Following gene: 71892142

Centisome position: 55.75

GC content: 31.95

Gene sequence:

>1227_bases
ATGATAATCTATCCTATAGAAAAAATTAGATCAGATTTTCCTATATTAAACCGAATGATAAATAAATACCCTCTTACTTA
TCTTGATAGCGCCGCATCTGCTCAAAAACCTAATATTGTCATAGACTCACAAACTCATTACTATCGCAATGAATACGCTG
CCGTGCATCGAGGTATTCACACGTTAAGTACTGAATCAACTAATCAAATGGAAACAGTACGCTTACGTATTGCTAATTTT
ATCAATGCATCTAAAGAAGAAATTGTTTTTGTCAAAAGTACTACTGAAGCTATTAACCTAATTGCTAATAGTTGGGGACA
CAACTTTATAAATTATGGGGATAATATTATTATTAGCGAAATGGAACACCACGCCAATATTGTTCCATGGCAAGTATTAT
CAAAACATAAAAAAATTGTATTACATTACATACCATTAACTCCTAACGGTACATTAGATATATCCAGATTATCCAAACTT
ATAAATCATCGTACTCGACTCTTATCTATATCACATATCTCTAATGTTTTAGGAACAATTAATCCATTAACAGAAATAAT
CAGTATAGCACGAAAAAAAAGTGATACTCTTATTTTAATAGATGGCGCACAAGGAATCGTCCATCAATTAGTAGACGTAC
AAAAATTAGATTGTGATTTTTATGTATTTTCTGGGCATAAAATATACGGACCTTCTGGTACTGGCATTATGTATGGAAAA
AAAGAATTACTTCAAAAAATGCCCCCATGGATAGTAGGAGGCGGAATAGTAAGAAATGTAAGTTTAATTCAAGATGCAAC
ATTTATAGATTCTCCTTGGAAATTTGAGTCAGGATCTCCTAATATTAGTGGTATCATAGGATTAGGTAATGCTATTGAAT
ACATCAATACAATAGGTATCGACAAAATTTACAATTACGAAGATCAATTAATGCGTTACGCTGTAGATACATTAAAAAAA
ATTCCAAATATAGTATTATACGGACCAAGTACACGAGTTGGTATTATTGCTTTTAATTTGGGGATACATCATTCATATGA
TATTGGAATGTTGTTAAACCAATATGGCGTTGCTATACGCACAGGACATCATTGCGCAATACCTATTATGAACTATTTTA
AAGTACCAGGTATGTGTCGTGCATCTTTAGCTATGTATACAAACAAGGAAGATATTGATCGTTTAGCACATGGACTAATT
AAAGTGGAACATTTACTGAACCAATGA

Upstream 100 bases:

>100_bases
TTTATGCTTTTGCTATTGAAATTATAGGATCAATTGAAAATACTATACTACAGGATCTTGTATTAAAAAGATTTAATAAA
GCTTTAGCAAGGATCATAAT

Downstream 100 bases:

>100_bases
ACAATTACTCTAATAACGATGATAAATTTTCCAACAAAAAACCAATTATTACAAAATTTCTTAAGTTGTATTAATTGGGA
AGAAAAATATATATATATAA

Product: selenocysteine lyase

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MIIYPIEKIRSDFPILNRMINKYPLTYLDSAASAQKPNIVIDSQTHYYRNEYAAVHRGIHTLSTESTNQMETVRLRIANF
INASKEEIVFVKSTTEAINLIANSWGHNFINYGDNIIISEMEHHANIVPWQVLSKHKKIVLHYIPLTPNGTLDISRLSKL
INHRTRLLSISHISNVLGTINPLTEIISIARKKSDTLILIDGAQGIVHQLVDVQKLDCDFYVFSGHKIYGPSGTGIMYGK
KELLQKMPPWIVGGGIVRNVSLIQDATFIDSPWKFESGSPNISGIIGLGNAIEYINTIGIDKIYNYEDQLMRYAVDTLKK
IPNIVLYGPSTRVGIIAFNLGIHHSYDIGMLLNQYGVAIRTGHHCAIPIMNYFKVPGMCRASLAMYTNKEDIDRLAHGLI
KVEHLLNQ

Sequences:

>Translated_408_residues
MIIYPIEKIRSDFPILNRMINKYPLTYLDSAASAQKPNIVIDSQTHYYRNEYAAVHRGIHTLSTESTNQMETVRLRIANF
INASKEEIVFVKSTTEAINLIANSWGHNFINYGDNIIISEMEHHANIVPWQVLSKHKKIVLHYIPLTPNGTLDISRLSKL
INHRTRLLSISHISNVLGTINPLTEIISIARKKSDTLILIDGAQGIVHQLVDVQKLDCDFYVFSGHKIYGPSGTGIMYGK
KELLQKMPPWIVGGGIVRNVSLIQDATFIDSPWKFESGSPNISGIIGLGNAIEYINTIGIDKIYNYEDQLMRYAVDTLKK
IPNIVLYGPSTRVGIIAFNLGIHHSYDIGMLLNQYGVAIRTGHHCAIPIMNYFKVPGMCRASLAMYTNKEDIDRLAHGLI
KVEHLLNQ
>Mature_408_residues
MIIYPIEKIRSDFPILNRMINKYPLTYLDSAASAQKPNIVIDSQTHYYRNEYAAVHRGIHTLSTESTNQMETVRLRIANF
INASKEEIVFVKSTTEAINLIANSWGHNFINYGDNIIISEMEHHANIVPWQVLSKHKKIVLHYIPLTPNGTLDISRLSKL
INHRTRLLSISHISNVLGTINPLTEIISIARKKSDTLILIDGAQGIVHQLVDVQKLDCDFYVFSGHKIYGPSGTGIMYGK
KELLQKMPPWIVGGGIVRNVSLIQDATFIDSPWKFESGSPNISGIIGLGNAIEYINTIGIDKIYNYEDQLMRYAVDTLKK
IPNIVLYGPSTRVGIIAFNLGIHHSYDIGMLLNQYGVAIRTGHHCAIPIMNYFKVPGMCRASLAMYTNKEDIDRLAHGLI
KVEHLLNQ

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=342, Percent_Identity=24.8538011695906, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI156713448, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=57.1428571428571, Blast_Score=520, Evalue=1e-149,
Organism=Escherichia coli, GI1789175, Length=408, Percent_Identity=37.5, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI48994898, Length=348, Percent_Identity=22.9885057471264, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=341, Percent_Identity=24.633431085044, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=371, Percent_Identity=25.8760107816712, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17533177, Length=223, Percent_Identity=25.5605381165919, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319831, Length=234, Percent_Identity=27.7777777777778, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI20129463, Length=406, Percent_Identity=25.1231527093596, Blast_Score=121, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 45931; Mature: 45931

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIYPIEKIRSDFPILNRMINKYPLTYLDSAASAQKPNIVIDSQTHYYRNEYAAVHRGIH
CEEECHHHHCCCCHHHHHHHHHCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCHH
TLSTESTNQMETVRLRIANFINASKEEIVFVKSTTEAINLIANSWGHNFINYGDNIIISE
HCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCHHHCCCCEEEEE
MEHHANIVPWQVLSKHKKIVLHYIPLTPNGTLDISRLSKLINHRTRLLSISHISNVLGTI
HHHCCCCCCHHHHCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHEEEHHHHHHHHHHH
NPLTEIISIARKKSDTLILIDGAQGIVHQLVDVQKLDCDFYVFSGHKIYGPSGTGIMYGK
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECEEEECCCCCEEECCH
KELLQKMPPWIVGGGIVRNVSLIQDATFIDSPWKFESGSPNISGIIGLGNAIEYINTIGI
HHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCC
DKIYNYEDQLMRYAVDTLKKIPNIVLYGPSTRVGIIAFNLGIHHSYDIGMLLNQYGVAIR
HHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCEEEE
TGHHCAIPIMNYFKVPGMCRASLAMYTNKEDIDRLAHGLIKVEHLLNQ
CCCEEEECHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIYPIEKIRSDFPILNRMINKYPLTYLDSAASAQKPNIVIDSQTHYYRNEYAAVHRGIH
CEEECHHHHCCCCHHHHHHHHHCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHCHH
TLSTESTNQMETVRLRIANFINASKEEIVFVKSTTEAINLIANSWGHNFINYGDNIIISE
HCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCHHHCCCCEEEEE
MEHHANIVPWQVLSKHKKIVLHYIPLTPNGTLDISRLSKLINHRTRLLSISHISNVLGTI
HHHCCCCCCHHHHCCCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHEEEHHHHHHHHHHH
NPLTEIISIARKKSDTLILIDGAQGIVHQLVDVQKLDCDFYVFSGHKIYGPSGTGIMYGK
HHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECEEEECCCCCEEECCH
KELLQKMPPWIVGGGIVRNVSLIQDATFIDSPWKFESGSPNISGIIGLGNAIEYINTIGI
HHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCC
DKIYNYEDQLMRYAVDTLKKIPNIVLYGPSTRVGIIAFNLGIHHSYDIGMLLNQYGVAIR
HHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCEEEE
TGHHCAIPIMNYFKVPGMCRASLAMYTNKEDIDRLAHGLIKVEHLLNQ
CCCEEEECHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA