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The map label for this gene is pgm [H]

Identifier: 71892104

GI number: 71892104

Start: 395951

End: 397609

Strand: Direct

Name: pgm [H]

Synonym: BPEN_335

Alternate gene names: 71892104

Gene position: 395951-397609 (Clockwise)

Preceding gene: 71892101

Following gene: 71892105

Centisome position: 50.02

GC content: 31.77

Gene sequence:

>1659_bases
ATGAAGAATCATATCCATTCTGGACAACTAGCGTCACATAATGAAGTTATTAATACATCTCGATTAATAACACAATATTA
TACTTTATCTCCCGATCCAAGTAATGGCGCTCATAATGTTGTATTTGGTACTTCAGGTCATCGTGGTAGTTCTCAAAGAT
ACAGTTTTAATGAAGCACACGTATTAGCAATTAGTCAATCGATTGTACAAGTACGCGCACAACAAGGTATATCTGGGCCA
TGTTACATTGGAAAAGATACGCACGCTCTTTCTGAACCAGCATTTATATCTGTACTTGAAGTATTAGCGGCTAATTTCGT
CGATGTTATTGTTCAAAAAAATAATGGTTATACTCCAACCCCTGTTATTTCTCATGCTATCACTCAATATAATAAAAATC
ATCATAATAATCATTCAAAAAAAGCTGATGGTATCATCATTACATCTTCCCATAATCCACCTGAAGATGGTGGTATAAAA
TATAATTCAATATATGGAGGACCAGCTCCTACTAATATAACTCGCACAATTGAACAAATCGCTAATAAATTTTTAGTGAA
TAATCTACAACACGTACGCCGTATGACGTTGAAAAATGCTTGGAAAAGCGGTTATATACACACACAAGATTTCATTCAAA
ATTACGTAAAAAAACTATCTACAATAATTGATATGCAAGCCATAAAAACATCTGGTTTGAAACTGGGAGTACATCCCTTA
AGTGGATCAAGTATAGATTATTGGCAAAACATTGCCCAATTTTATCAATTAGATTTAAATTTAATCAGTGAAAAAATTGA
TAAAACTTTTGGTTTTATACATCTTGATTATGATGGCTGTATTCGATTAGATTGCTCTTCTGAATTCGCAATGGCTGGAG
TATTAAAGTCACATGATAATTTTGATTTGCTTTTAGTTAATGACCCAGATTGTGATAGACATGGAATTATTACTCCTATT
GGTTTAATAAAACCTAATCATTATCTTATTATTGCAGCGCATTACCTTTTTAACAATCGTCCATTGTGGCGTAATCGTTC
ACTATTCATAGGAAAAACTTATGTATCTAGTATTATGATGAATCACGTAGCATACGATCTCTCTCGTCAATTGATAGAAG
TACCAGTAGGTTTTAAATGGTTTGTACGAGGATTATTTAATAGCTTATTCGGTTTTGTAGGCGAGGAAAGCGCAGGAGCA
TCTTTCTTAGATTTTTATTGCTCTCCATGGTCTACTGATAAAGATGGGCTAATTATGTGTCTATTAGCGGCTGAAATGAT
TGCTATTAGTGATAAATCTTTACAAAAGTATTATGATCAATTGGTTCAAAATTTTGGTATATCTAATTATAATCGTATTC
AATTACCTATTAATTACACACAAAAATCCATTATCTCTAACACATTATTTAATCAGATTAATATGACAGAATTAGCAGAT
GATCCTATTACTAAAATCATAAATATGAGTTCATTAAAAAATCAAATATCTATGGATGGTGTAAAAATCATCACTCACAA
TGGTTGGGTGGCGTGTCGATTATCAGGCACTGAATCAGTGTACAAAATTTATTGCGAAAGCTTTTTAAGTGTTTCTCATA
GAAAAAAGATTGAAAAAGAAATAATAAGTATCATCGATACTATCATCAATCAATCTTAA

Upstream 100 bases:

>100_bases
ATATTAAAGACCACAAATTCAATACCCTGGTAGACCCTACGAAAATGATATCATAATATTTTTAAAATTTCATAAAATAA
TCAATTTAGGGGATTTTCGA

Downstream 100 bases:

>100_bases
TATAAAAGACACACGATAATAAATTGAATGAATAGTATTGAATAATTACAGATTATTAGTCTTTATTGTTATTTAACAAG
ACCTTATAACAAGGATACAA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKNHIHSGQLASHNEVINTSRLITQYYTLSPDPSNGAHNVVFGTSGHRGSSQRYSFNEAHVLAISQSIVQVRAQQGISGP
CYIGKDTHALSEPAFISVLEVLAANFVDVIVQKNNGYTPTPVISHAITQYNKNHHNNHSKKADGIIITSSHNPPEDGGIK
YNSIYGGPAPTNITRTIEQIANKFLVNNLQHVRRMTLKNAWKSGYIHTQDFIQNYVKKLSTIIDMQAIKTSGLKLGVHPL
SGSSIDYWQNIAQFYQLDLNLISEKIDKTFGFIHLDYDGCIRLDCSSEFAMAGVLKSHDNFDLLLVNDPDCDRHGIITPI
GLIKPNHYLIIAAHYLFNNRPLWRNRSLFIGKTYVSSIMMNHVAYDLSRQLIEVPVGFKWFVRGLFNSLFGFVGEESAGA
SFLDFYCSPWSTDKDGLIMCLLAAEMIAISDKSLQKYYDQLVQNFGISNYNRIQLPINYTQKSIISNTLFNQINMTELAD
DPITKIINMSSLKNQISMDGVKIITHNGWVACRLSGTESVYKIYCESFLSVSHRKKIEKEIISIIDTIINQS

Sequences:

>Translated_552_residues
MKNHIHSGQLASHNEVINTSRLITQYYTLSPDPSNGAHNVVFGTSGHRGSSQRYSFNEAHVLAISQSIVQVRAQQGISGP
CYIGKDTHALSEPAFISVLEVLAANFVDVIVQKNNGYTPTPVISHAITQYNKNHHNNHSKKADGIIITSSHNPPEDGGIK
YNSIYGGPAPTNITRTIEQIANKFLVNNLQHVRRMTLKNAWKSGYIHTQDFIQNYVKKLSTIIDMQAIKTSGLKLGVHPL
SGSSIDYWQNIAQFYQLDLNLISEKIDKTFGFIHLDYDGCIRLDCSSEFAMAGVLKSHDNFDLLLVNDPDCDRHGIITPI
GLIKPNHYLIIAAHYLFNNRPLWRNRSLFIGKTYVSSIMMNHVAYDLSRQLIEVPVGFKWFVRGLFNSLFGFVGEESAGA
SFLDFYCSPWSTDKDGLIMCLLAAEMIAISDKSLQKYYDQLVQNFGISNYNRIQLPINYTQKSIISNTLFNQINMTELAD
DPITKIINMSSLKNQISMDGVKIITHNGWVACRLSGTESVYKIYCESFLSVSHRKKIEKEIISIIDTIINQS
>Mature_552_residues
MKNHIHSGQLASHNEVINTSRLITQYYTLSPDPSNGAHNVVFGTSGHRGSSQRYSFNEAHVLAISQSIVQVRAQQGISGP
CYIGKDTHALSEPAFISVLEVLAANFVDVIVQKNNGYTPTPVISHAITQYNKNHHNNHSKKADGIIITSSHNPPEDGGIK
YNSIYGGPAPTNITRTIEQIANKFLVNNLQHVRRMTLKNAWKSGYIHTQDFIQNYVKKLSTIIDMQAIKTSGLKLGVHPL
SGSSIDYWQNIAQFYQLDLNLISEKIDKTFGFIHLDYDGCIRLDCSSEFAMAGVLKSHDNFDLLLVNDPDCDRHGIITPI
GLIKPNHYLIIAAHYLFNNRPLWRNRSLFIGKTYVSSIMMNHVAYDLSRQLIEVPVGFKWFVRGLFNSLFGFVGEESAGA
SFLDFYCSPWSTDKDGLIMCLLAAEMIAISDKSLQKYYDQLVQNFGISNYNRIQLPINYTQKSIISNTLFNQINMTELAD
DPITKIINMSSLKNQISMDGVKIITHNGWVACRLSGTESVYKIYCESFLSVSHRKKIEKEIISIIDTIINQS

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=543, Percent_Identity=23.9410681399632, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI21361621, Length=536, Percent_Identity=23.8805970149254, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1786904, Length=552, Percent_Identity=54.8913043478261, Blast_Score=649, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=436, Percent_Identity=25.4587155963303, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323752, Length=560, Percent_Identity=23.2142857142857, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322722, Length=441, Percent_Identity=25.1700680272109, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17864244, Length=470, Percent_Identity=25.3191489361702, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 62020; Mature: 62020

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHIHSGQLASHNEVINTSRLITQYYTLSPDPSNGAHNVVFGTSGHRGSSQRYSFNEAH
CCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCE
VLAISQSIVQVRAQQGISGPCYIGKDTHALSEPAFISVLEVLAANFVDVIVQKNNGYTPT
EEHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCC
PVISHAITQYNKNHHNNHSKKADGIIITSSHNPPEDGGIKYNSIYGGPAPTNITRTIEQI
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
ANKFLVNNLQHVRRMTLKNAWKSGYIHTQDFIQNYVKKLSTIIDMQAIKTSGLKLGVHPL
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SGSSIDYWQNIAQFYQLDLNLISEKIDKTFGFIHLDYDGCIRLDCSSEFAMAGVLKSHDN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCCHHHHHHHHCCCC
FDLLLVNDPDCDRHGIITPIGLIKPNHYLIIAAHYLFNNRPLWRNRSLFIGKTYVSSIMM
EEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEEHHCCCCCCCCCCEEEEHHHHHHHHH
NHVAYDLSRQLIEVPVGFKWFVRGLFNSLFGFVGEESAGASFLDFYCSPWSTDKDGLIMC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHH
LLAAEMIAISDKSLQKYYDQLVQNFGISNYNRIQLPINYTQKSIISNTLFNQINMTELAD
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHCC
DPITKIINMSSLKNQISMDGVKIITHNGWVACRLSGTESVYKIYCESFLSVSHRKKIEKE
CHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IISIIDTIINQS
HHHHHHHHHCCC
>Mature Secondary Structure
MKNHIHSGQLASHNEVINTSRLITQYYTLSPDPSNGAHNVVFGTSGHRGSSQRYSFNEAH
CCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCE
VLAISQSIVQVRAQQGISGPCYIGKDTHALSEPAFISVLEVLAANFVDVIVQKNNGYTPT
EEHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCC
PVISHAITQYNKNHHNNHSKKADGIIITSSHNPPEDGGIKYNSIYGGPAPTNITRTIEQI
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
ANKFLVNNLQHVRRMTLKNAWKSGYIHTQDFIQNYVKKLSTIIDMQAIKTSGLKLGVHPL
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SGSSIDYWQNIAQFYQLDLNLISEKIDKTFGFIHLDYDGCIRLDCSSEFAMAGVLKSHDN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCCHHHHHHHHCCCC
FDLLLVNDPDCDRHGIITPIGLIKPNHYLIIAAHYLFNNRPLWRNRSLFIGKTYVSSIMM
EEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEEHHCCCCCCCCCCEEEEHHHHHHHHH
NHVAYDLSRQLIEVPVGFKWFVRGLFNSLFGFVGEESAGASFLDFYCSPWSTDKDGLIMC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHH
LLAAEMIAISDKSLQKYYDQLVQNFGISNYNRIQLPINYTQKSIISNTLFNQINMTELAD
HHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHCC
DPITKIINMSSLKNQISMDGVKIITHNGWVACRLSGTESVYKIYCESFLSVSHRKKIEKE
CHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IISIIDTIINQS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]