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The map label for this gene is glnS [H]

Identifier: 71892101

GI number: 71892101

Start: 392299

End: 393957

Strand: Direct

Name: glnS [H]

Synonym: BPEN_332

Alternate gene names: 71892101

Gene position: 392299-393957 (Clockwise)

Preceding gene: 71892400

Following gene: 71892104

Centisome position: 49.55

GC content: 31.28

Gene sequence:

>1659_bases
ATGAAAATTCTTATGAATTATCGACCTAATTTTATTAACCATATTATTGATAAAGATTTGAAATCAAAGAAACATACTAA
TGTGCGCACACGATTTCCTCCAGAACCTAATGGATATTTACATATCGGACATGCTAAAGCTATTTGCCTCAATTTTGGTA
TTGCTCAATATTATCATGGTCAATGCAATTTACGATTTGATGATACCAATCCAGAAAAAGAACACAAAGAATATGTTGAA
AGTATAAAATATGACATTCAATGGCTTGGATTTATGTGGCACGGAGATGTACATTATTCATCCGATTATATTGAAGAATT
GTATGATTATGCTATCAAATTAATTAAAAAGGGTCTAGCATATGTAGACGAATTATCCATAGATGAAATTAAAAAATACC
GGGGAACATTAACACGTTCTGGTAAAAATAGCCCATACCGATCTCGTAGTATTAAAGAAAATTTAATTTATTTTTCTAAA
ATGCGAAATGGGGATTTTCTAGAAGGTAAGGCCTGTTTACGTGCTAAAATTAATATGGCCTCTCCTTCTATGGTGATGCG
AGATCCGGTATTATATCGTATTAAATACACTCCACATCATCGCATTGGAAAAAATTGGTGTATTTATCCAACATACGATT
TTAGTCATTGTATTTCAGATGCAATAGAAGGTATTACTCATTCTTTATGTACTTTAGAATTCCAAGAGAATCGCATTCTA
TATAATTGGATATTAAATAATATTGATATAAATACACACCCCGCTCAATATGAATTTTCTCGGCTTAACTTAAAATATAT
AATCACATCTAAACGTAAACTTAATATATTAGTTACAAAAAACATAGTTGATGGATGGGATGATCCTCGAATGCCTACTA
TTTCTGGATTACGACGCAGAGGATATACAGCCAGATCAATTCGCGAATTTTGTCATCGTATCGGCATCAGTAAACAAGAA
AGTCAAATAGAATTATCACTTTTAGAATCATGTATTCGTGCGGATTTAAACAAACATGCGCCACGACTTATGGCAGTAAT
CAATCCAATGAAAATTATTATTAATAATTTACCTGTAGGATATGAAGAAAAAATAGAAATGCCAAATCATCCTAATAACT
CTGATATGGGGGTGCGTCATGTCATTTTTAGTCAAGAAATTTTTATTGATCGTTTTGATTTTTGCGAAATATTAAATAAC
AATGAATGTTATAAATTAACTTTTGGGCAGGAGATACGATTAAGATACGCTTATGTCATAAAAGCAGAGGGTGTCAAAAA
AGATAAAAATGGAAATATCATTTGTATTTACTGCAGTTACGATCCATTTACTTTACATAAAAACCCAGTAGGTGGCAGAA
AAATTACTAGAGTAATCCATTGGGTATCAGCAACAAGAAACATATCAGCTGAATTTCGTCTATATGATAAATTATTTATT
CACCCCAATCCTGCTGTTGCAAGCAACTTGATTGCCAATATCAATCCTAATTCTTTAATAATTTCTCAAGGAGTTGTTGA
AGAAAATATAATTCACTCTTATAGCTCTGGTCCATACCAAATTGAACGAGAAGGATATTTTATCCTGGACCACCATTATT
CTAAAAAATCTTACCTAGTATTTAACAGAACCGTAACCTTAAAAGAATCTAAAAATTAG

Upstream 100 bases:

>100_bases
TTTATGTAATAATCTTCATTCGATATCGTCATTTAAATTAATGAAGATATGTTATCTACGGATTAGCAATGATAGTATAT
ATTTAGAAAAGGATAAAAGA

Downstream 100 bases:

>100_bases
TAAAGAAATACACTCAAATTGTTACACAATTATATCTAGTTAATCTTTCTATTGATTAACAATCATACCGCAAACATAAA
AATAGTATGTTGATACATGA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKILMNYRPNFINHIIDKDLKSKKHTNVRTRFPPEPNGYLHIGHAKAICLNFGIAQYYHGQCNLRFDDTNPEKEHKEYVE
SIKYDIQWLGFMWHGDVHYSSDYIEELYDYAIKLIKKGLAYVDELSIDEIKKYRGTLTRSGKNSPYRSRSIKENLIYFSK
MRNGDFLEGKACLRAKINMASPSMVMRDPVLYRIKYTPHHRIGKNWCIYPTYDFSHCISDAIEGITHSLCTLEFQENRIL
YNWILNNIDINTHPAQYEFSRLNLKYIITSKRKLNILVTKNIVDGWDDPRMPTISGLRRRGYTARSIREFCHRIGISKQE
SQIELSLLESCIRADLNKHAPRLMAVINPMKIIINNLPVGYEEKIEMPNHPNNSDMGVRHVIFSQEIFIDRFDFCEILNN
NECYKLTFGQEIRLRYAYVIKAEGVKKDKNGNIICIYCSYDPFTLHKNPVGGRKITRVIHWVSATRNISAEFRLYDKLFI
HPNPAVASNLIANINPNSLIISQGVVEENIIHSYSSGPYQIEREGYFILDHHYSKKSYLVFNRTVTLKESKN

Sequences:

>Translated_552_residues
MKILMNYRPNFINHIIDKDLKSKKHTNVRTRFPPEPNGYLHIGHAKAICLNFGIAQYYHGQCNLRFDDTNPEKEHKEYVE
SIKYDIQWLGFMWHGDVHYSSDYIEELYDYAIKLIKKGLAYVDELSIDEIKKYRGTLTRSGKNSPYRSRSIKENLIYFSK
MRNGDFLEGKACLRAKINMASPSMVMRDPVLYRIKYTPHHRIGKNWCIYPTYDFSHCISDAIEGITHSLCTLEFQENRIL
YNWILNNIDINTHPAQYEFSRLNLKYIITSKRKLNILVTKNIVDGWDDPRMPTISGLRRRGYTARSIREFCHRIGISKQE
SQIELSLLESCIRADLNKHAPRLMAVINPMKIIINNLPVGYEEKIEMPNHPNNSDMGVRHVIFSQEIFIDRFDFCEILNN
NECYKLTFGQEIRLRYAYVIKAEGVKKDKNGNIICIYCSYDPFTLHKNPVGGRKITRVIHWVSATRNISAEFRLYDKLFI
HPNPAVASNLIANINPNSLIISQGVVEENIIHSYSSGPYQIEREGYFILDHHYSKKSYLVFNRTVTLKESKN
>Mature_552_residues
MKILMNYRPNFINHIIDKDLKSKKHTNVRTRFPPEPNGYLHIGHAKAICLNFGIAQYYHGQCNLRFDDTNPEKEHKEYVE
SIKYDIQWLGFMWHGDVHYSSDYIEELYDYAIKLIKKGLAYVDELSIDEIKKYRGTLTRSGKNSPYRSRSIKENLIYFSK
MRNGDFLEGKACLRAKINMASPSMVMRDPVLYRIKYTPHHRIGKNWCIYPTYDFSHCISDAIEGITHSLCTLEFQENRIL
YNWILNNIDINTHPAQYEFSRLNLKYIITSKRKLNILVTKNIVDGWDDPRMPTISGLRRRGYTARSIREFCHRIGISKQE
SQIELSLLESCIRADLNKHAPRLMAVINPMKIIINNLPVGYEEKIEMPNHPNNSDMGVRHVIFSQEIFIDRFDFCEILNN
NECYKLTFGQEIRLRYAYVIKAEGVKKDKNGNIICIYCSYDPFTLHKNPVGGRKITRVIHWVSATRNISAEFRLYDKLFI
HPNPAVASNLIANINPNSLIISQGVVEENIIHSYSSGPYQIEREGYFILDHHYSKKSYLVFNRTVTLKESKN

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=529, Percent_Identity=44.0453686200378, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=519, Percent_Identity=34.1040462427746, Blast_Score=270, Evalue=3e-72,
Organism=Escherichia coli, GI1786895, Length=544, Percent_Identity=64.7058823529412, Blast_Score=739, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=203, Percent_Identity=23.6453201970443, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543332, Length=531, Percent_Identity=41.0546139359699, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=527, Percent_Identity=30.550284629981, Blast_Score=232, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6324742, Length=563, Percent_Identity=39.7868561278863, Blast_Score=392, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321192, Length=517, Percent_Identity=36.3636363636364, Blast_Score=316, Evalue=5e-87,
Organism=Drosophila melanogaster, GI17864488, Length=529, Percent_Identity=40.4536862003781, Blast_Score=404, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24649466, Length=419, Percent_Identity=36.5155131264916, Blast_Score=259, Evalue=4e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64589; Mature: 64589

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILMNYRPNFINHIIDKDLKSKKHTNVRTRFPPEPNGYLHIGHAKAICLNFGIAQYYHG
CEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCCEEEEEECCHHHEECC
QCNLRFDDTNPEKEHKEYVESIKYDIQWLGFMWHGDVHYSSDYIEELYDYAIKLIKKGLA
EEEEEECCCCCHHHHHHHHHHHHHCEEEEEEEEECCEECCHHHHHHHHHHHHHHHHHHHH
YVDELSIDEIKKYRGTLTRSGKNSPYRSRSIKENLIYFSKMRNGDFLEGKACLRAKINMA
HHHCCCHHHHHHHHCHHCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCC
SPSMVMRDPVLYRIKYTPHHRIGKNWCIYPTYDFSHCISDAIEGITHSLCTLEFQENRIL
CCCEEECCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCEEE
YNWILNNIDINTHPAQYEFSRLNLKYIITSKRKLNILVTKNIVDGWDDPRMPTISGLRRR
EEEEECCCCCCCCCCCEEHEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHC
GYTARSIREFCHRIGISKQESQIELSLLESCIRADLNKHAPRLMAVINPMKIIINNLPVG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
YEEKIEMPNHPNNSDMGVRHVIFSQEIFIDRFDFCEILNNNECYKLTFGQEIRLRYAYVI
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEE
KAEGVKKDKNGNIICIYCSYDPFTLHKNPVGGRKITRVIHWVSATRNISAEFRLYDKLFI
EECCCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEE
HPNPAVASNLIANINPNSLIISQGVVEENIIHSYSSGPYQIEREGYFILDHHYSKKSYLV
CCCHHHHHHHEECCCCCEEEEECCCHHHHHHHCCCCCCEEEECCCEEEEEECCCCCEEEE
FNRTVTLKESKN
EEEEEEEEECCC
>Mature Secondary Structure
MKILMNYRPNFINHIIDKDLKSKKHTNVRTRFPPEPNGYLHIGHAKAICLNFGIAQYYHG
CEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCCEEEEEECCHHHEECC
QCNLRFDDTNPEKEHKEYVESIKYDIQWLGFMWHGDVHYSSDYIEELYDYAIKLIKKGLA
EEEEEECCCCCHHHHHHHHHHHHHCEEEEEEEEECCEECCHHHHHHHHHHHHHHHHHHHH
YVDELSIDEIKKYRGTLTRSGKNSPYRSRSIKENLIYFSKMRNGDFLEGKACLRAKINMA
HHHCCCHHHHHHHHCHHCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCEEEEEEECCC
SPSMVMRDPVLYRIKYTPHHRIGKNWCIYPTYDFSHCISDAIEGITHSLCTLEFQENRIL
CCCEEECCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCEEE
YNWILNNIDINTHPAQYEFSRLNLKYIITSKRKLNILVTKNIVDGWDDPRMPTISGLRRR
EEEEECCCCCCCCCCCEEHEEEEEEEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHC
GYTARSIREFCHRIGISKQESQIELSLLESCIRADLNKHAPRLMAVINPMKIIINNLPVG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
YEEKIEMPNHPNNSDMGVRHVIFSQEIFIDRFDFCEILNNNECYKLTFGQEIRLRYAYVI
HHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEE
KAEGVKKDKNGNIICIYCSYDPFTLHKNPVGGRKITRVIHWVSATRNISAEFRLYDKLFI
EECCCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEE
HPNPAVASNLIANINPNSLIISQGVVEENIIHSYSSGPYQIEREGYFILDHHYSKKSYLV
CCCHHHHHHHEECCCCCEEEEECCCHHHHHHHCCCCCCEEEECCCEEEEEECCCCCEEEE
FNRTVTLKESKN
EEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA