Click here to switch to the map view.

The map label for this gene is nagB [H]

Identifier: 71892100

GI number: 71892100

Start: 390580

End: 391383

Strand: Reverse

Name: nagB [H]

Synonym: BPEN_331

Alternate gene names: 71892100

Gene position: 391383-390580 (Counterclockwise)

Preceding gene: 71892102

Following gene: 71892099

Centisome position: 49.44

GC content: 31.22

Gene sequence:

>804_bases
ATGAGAGTTATATTTTTAGATACCTCTGATCACGTTGCTCAATGGGTTGCGCACTACGTTGTTTGCCGTATTAATTCTTT
TCATCCTACCATCGACAATCCGTTTGTATTAGGTTTACCTGCAGGAAGAACTCCAATAAAGACTTATAAAAATATTATAG
CGCTGCATCGGTCTAATCAAGTAAGTTTTAAATATGTAGTAATATTTACTATGGACGAATATCTTGGTTTATCTCATACA
GATTTAAAAAGCTATTATACTTTTATACATACAAATTTTATTGATCATGTTGATATTCCTAAAGAAAATGTCTACGTTTT
AAATGGAAATACCAATAATGTTAAAGATGAATGTCAACGATATGAAGAAAAAATAAAATTATATGGGGGTATTCATTTGT
TGATAGGGGGGGTTGGTAGTGATGGACATCTTGCTTTCAATGAACCTGGCTCTTCTTTAACATCGCGCACCAGACTTAAA
AACTTAAGTAAAGAAACTCGTGTATCAAATGCTAAGTTTTTTAATAATAATATTGATTCTGTCCCTAAATTTGCATTAAC
TATTGGAATTGCTACATTAATGGAGTCACGAGAAATAATAATAATAGCAACTGGAATAAATAAAGCAGCGGCAGTACAAG
CAGCAATTGAAGGTAATGTTAATCATATGTGGACTATTAGTTGTCTACAGTTACATCCTAAATCAGTATTAGTATGCGAT
GAGCTATCAACTATGGAATTAAAAATGAAAACAGTCAAGTATTTTCGAGAACTAGAAATAAATAATCAGACAATCATAAT
GTAA

Upstream 100 bases:

>100_bases
TCAGGTCCGCAATTAACCATATATGTATATATAGTGTTTTATTAGTTTTTAAATAATATAGGATGATTTATTATCAGCTC
AATTAAACAAGGATCTTTAT

Downstream 100 bases:

>100_bases
TTTCTAAAATATGTATGCTTTAATTAATAGTACGATATACACTGGTAAGGAAATTATTGATAATCATGCGCTTATCGTTT
CTGAAAATGTTATTAAAGCT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MRVIFLDTSDHVAQWVAHYVVCRINSFHPTIDNPFVLGLPAGRTPIKTYKNIIALHRSNQVSFKYVVIFTMDEYLGLSHT
DLKSYYTFIHTNFIDHVDIPKENVYVLNGNTNNVKDECQRYEEKIKLYGGIHLLIGGVGSDGHLAFNEPGSSLTSRTRLK
NLSKETRVSNAKFFNNNIDSVPKFALTIGIATLMESREIIIIATGINKAAAVQAAIEGNVNHMWTISCLQLHPKSVLVCD
ELSTMELKMKTVKYFRELEINNQTIIM

Sequences:

>Translated_267_residues
MRVIFLDTSDHVAQWVAHYVVCRINSFHPTIDNPFVLGLPAGRTPIKTYKNIIALHRSNQVSFKYVVIFTMDEYLGLSHT
DLKSYYTFIHTNFIDHVDIPKENVYVLNGNTNNVKDECQRYEEKIKLYGGIHLLIGGVGSDGHLAFNEPGSSLTSRTRLK
NLSKETRVSNAKFFNNNIDSVPKFALTIGIATLMESREIIIIATGINKAAAVQAAIEGNVNHMWTISCLQLHPKSVLVCD
ELSTMELKMKTVKYFRELEINNQTIIM
>Mature_267_residues
MRVIFLDTSDHVAQWVAHYVVCRINSFHPTIDNPFVLGLPAGRTPIKTYKNIIALHRSNQVSFKYVVIFTMDEYLGLSHT
DLKSYYTFIHTNFIDHVDIPKENVYVLNGNTNNVKDECQRYEEKIKLYGGIHLLIGGVGSDGHLAFNEPGSSLTSRTRLK
NLSKETRVSNAKFFNNNIDSVPKFALTIGIATLMESREIIIIATGINKAAAVQAAIEGNVNHMWTISCLQLHPKSVLVCD
ELSTMELKMKTVKYFRELEINNQTIIM

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=49.6124031007752, Blast_Score=289, Evalue=2e-78,
Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=49.6124031007752, Blast_Score=286, Evalue=1e-77,
Organism=Escherichia coli, GI1786893, Length=262, Percent_Identity=59.5419847328244, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789530, Length=197, Percent_Identity=25.3807106598985, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17554876, Length=268, Percent_Identity=45.5223880597015, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24581960, Length=256, Percent_Identity=51.171875, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI19920764, Length=256, Percent_Identity=51.171875, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 30206; Mature: 30206

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIFLDTSDHVAQWVAHYVVCRINSFHPTIDNPFVLGLPAGRTPIKTYKNIIALHRSNQ
CEEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHEEECCCC
VSFKYVVIFTMDEYLGLSHTDLKSYYTFIHTNFIDHVDIPKENVYVLNGNTNNVKDECQR
CEEEEEEEEEEHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHH
YEEKIKLYGGIHLLIGGVGSDGHLAFNEPGSSLTSRTRLKNLSKETRVSNAKFFNNNIDS
HHHHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
VPKFALTIGIATLMESREIIIIATGINKAAAVQAAIEGNVNHMWTISCLQLHPKSVLVCD
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHEEHHHCCCCCEEEEEEEEEECCCEEEEEC
ELSTMELKMKTVKYFRELEINNQTIIM
CCCHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MRVIFLDTSDHVAQWVAHYVVCRINSFHPTIDNPFVLGLPAGRTPIKTYKNIIALHRSNQ
CEEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHEEECCCC
VSFKYVVIFTMDEYLGLSHTDLKSYYTFIHTNFIDHVDIPKENVYVLNGNTNNVKDECQR
CEEEEEEEEEEHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHH
YEEKIKLYGGIHLLIGGVGSDGHLAFNEPGSSLTSRTRLKNLSKETRVSNAKFFNNNIDS
HHHHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
VPKFALTIGIATLMESREIIIIATGINKAAAVQAAIEGNVNHMWTISCLQLHPKSVLVCD
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHEEHHHCCCCCEEEEEEEEEECCCEEEEEC
ELSTMELKMKTVKYFRELEINNQTIIM
CCCHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12886019 [H]