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The map label for this gene is nagA [H]

Identifier: 71892099

GI number: 71892099

Start: 389409

End: 390569

Strand: Reverse

Name: nagA [H]

Synonym: BPEN_330

Alternate gene names: 71892099

Gene position: 390569-389409 (Counterclockwise)

Preceding gene: 71892100

Following gene: 71892098

Centisome position: 49.34

GC content: 32.64

Gene sequence:

>1161_bases
ATGTATGCTTTAATTAATAGTACGATATACACTGGTAAGGAAATTATTGATAATCATGCGCTTATCGTTTCTGAAAATGT
TATTAAAGCTATTTGTTTGAGTAGCGAGTTGCCTAAAAACATAGATGTACATGATTTATCAGGATCTTTATTGACACCTG
GATTTATAGATTTACAAATTAACGGGTGCGGCGGCGTACAATTCAACGATCATATAAATGCAATATCAATATGTACACTT
GAAAAAATGCAGGAAACTAACCAATTTTCAGGGTGTACTAGTTTTCTTCCAACGTTGATTACTAGTAATAATGTTCTGAT
GCAACGAGCTATTGAGATCATGCGTATTTTTTTATCTAAAAATAAAAATCAGGCTTTAGGATTACATTTGGAAGGGCCAT
TCTTAAACTCTACAAAAAGAGGTATACATAACCCGATATTGATTCGTTGTCCGACAAAAGAGATGATAAATTATCTGTGT
GAAAATAGTGATGTTATCAGAAAAATAACTCTTGCTCCCGAACAATTAGATATGACATTTATTCAAAAATTAAAAAAATC
GGGTATTTGTGTTGCAATTGGACATTCTAACGCTACTTATGAACAAGCACGATTTAGTTTCTCATACGGTGTTAGTTTTG
GAACCCATTTATTTAATGCTATGCCACCGTTAATTGCTCGTGAACCTGGTGTTATCGGAGCTATTTTTGATGTGCCAGAA
ATATATTGCAGTGTTATAGCAGATGGATTGCATGTTCATTGGGCTAATATTAGATATGCTAAAAAAATTAAAGGAGATCG
TTTAATTTTAGTAACTGATGCCACTAGTCCTGCGGGATCTAATAAAATTAGATCCCGATTTCTTTTTTCTAATAAAACCA
TATATCATCGTAATAACATATGTGAGGATAGTAAAGGCACACTTAGTGGATCGACTTTAACCATGATTCAAGCAATAAAA
AACAGTGTTAAATATGCTGGAATACCATTAGATGAAGCTGTGCGTATGGCTACCTTATATCCAGCCAAAGCTATCGGAAT
GGACCATTGTTTAGGTAGCTTAGAAATAAATAAGATTGCTAATTTAACTGTTTTTAACACAGACTATCAAATAAAAAAAA
CCATAGTTAACGGAAAAATAGTGAATACATCATTGCCATAA

Upstream 100 bases:

>100_bases
TGCGATGAGCTATCAACTATGGAATTAAAAATGAAAACAGTCAAGTATTTTCGAGAACTAGAAATAAATAATCAGACAAT
CATAATGTAATTTCTAAAAT

Downstream 100 bases:

>100_bases
ATTCGACTACATATAGACATATGCTTAAATAAATGTTCATCCATGATGGAATTTTTTATCTCATTAATGATCTTGTGTAT
TAAACTAACAATTTTTAAAT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MYALINSTIYTGKEIIDNHALIVSENVIKAICLSSELPKNIDVHDLSGSLLTPGFIDLQINGCGGVQFNDHINAISICTL
EKMQETNQFSGCTSFLPTLITSNNVLMQRAIEIMRIFLSKNKNQALGLHLEGPFLNSTKRGIHNPILIRCPTKEMINYLC
ENSDVIRKITLAPEQLDMTFIQKLKKSGICVAIGHSNATYEQARFSFSYGVSFGTHLFNAMPPLIAREPGVIGAIFDVPE
IYCSVIADGLHVHWANIRYAKKIKGDRLILVTDATSPAGSNKIRSRFLFSNKTIYHRNNICEDSKGTLSGSTLTMIQAIK
NSVKYAGIPLDEAVRMATLYPAKAIGMDHCLGSLEINKIANLTVFNTDYQIKKTIVNGKIVNTSLP

Sequences:

>Translated_386_residues
MYALINSTIYTGKEIIDNHALIVSENVIKAICLSSELPKNIDVHDLSGSLLTPGFIDLQINGCGGVQFNDHINAISICTL
EKMQETNQFSGCTSFLPTLITSNNVLMQRAIEIMRIFLSKNKNQALGLHLEGPFLNSTKRGIHNPILIRCPTKEMINYLC
ENSDVIRKITLAPEQLDMTFIQKLKKSGICVAIGHSNATYEQARFSFSYGVSFGTHLFNAMPPLIAREPGVIGAIFDVPE
IYCSVIADGLHVHWANIRYAKKIKGDRLILVTDATSPAGSNKIRSRFLFSNKTIYHRNNICEDSKGTLSGSTLTMIQAIK
NSVKYAGIPLDEAVRMATLYPAKAIGMDHCLGSLEINKIANLTVFNTDYQIKKTIVNGKIVNTSLP
>Mature_386_residues
MYALINSTIYTGKEIIDNHALIVSENVIKAICLSSELPKNIDVHDLSGSLLTPGFIDLQINGCGGVQFNDHINAISICTL
EKMQETNQFSGCTSFLPTLITSNNVLMQRAIEIMRIFLSKNKNQALGLHLEGPFLNSTKRGIHNPILIRCPTKEMINYLC
ENSDVIRKITLAPEQLDMTFIQKLKKSGICVAIGHSNATYEQARFSFSYGVSFGTHLFNAMPPLIAREPGVIGAIFDVPE
IYCSVIADGLHVHWANIRYAKKIKGDRLILVTDATSPAGSNKIRSRFLFSNKTIYHRNNICEDSKGTLSGSTLTMIQAIK
NSVKYAGIPLDEAVRMATLYPAKAIGMDHCLGSLEINKIANLTVFNTDYQIKKTIVNGKIVNTSLP

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=380, Percent_Identity=30, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI224922791, Length=413, Percent_Identity=28.5714285714286, Blast_Score=152, Evalue=7e-37,
Organism=Escherichia coli, GI1786892, Length=384, Percent_Identity=55.2083333333333, Blast_Score=465, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17553768, Length=358, Percent_Identity=29.608938547486, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19920392, Length=351, Percent_Identity=31.0541310541311, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281361140, Length=374, Percent_Identity=30.2139037433155, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42581; Mature: 42581

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALINSTIYTGKEIIDNHALIVSENVIKAICLSSELPKNIDVHDLSGSLLTPGFIDLQI
CEEEECCCCCCCHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEE
NGCGGVQFNDHINAISICTLEKMQETNQFSGCTSFLPTLITSNNVLMQRAIEIMRIFLSK
ECCCCCEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
NKNQALGLHLEGPFLNSTKRGIHNPILIRCPTKEMINYLCENSDVIRKITLAPEQLDMTF
CCCCEEEEEECCCCCCCHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IQKLKKSGICVAIGHSNATYEQARFSFSYGVSFGTHLFNAMPPLIAREPGVIGAIFDVPE
HHHHHHCCCEEEECCCCCCHHHHEEEEEECCHHHHHHHHHCCCHHHCCCCCEEEEHHHHH
IYCSVIADGLHVHWANIRYAKKIKGDRLILVTDATSPAGSNKIRSRFLFSNKTIYHRNNI
HHHHHHHCCCEEEEECEEEEHHCCCCEEEEEECCCCCCCCHHHHHHEEECCCEEEECCCC
CEDSKGTLSGSTLTMIQAIKNSVKYAGIPLDEAVRMATLYPAKAIGMDHCLGSLEINKIA
CCCCCCCCCCCHHHHHHHHHHCCEECCCCHHHHHHHHHCCCHHHCCHHHHCCCEEECCEE
NLTVFNTDYQIKKTIVNGKIVNTSLP
EEEEECCCCEEEEEEECCEEEECCCC
>Mature Secondary Structure
MYALINSTIYTGKEIIDNHALIVSENVIKAICLSSELPKNIDVHDLSGSLLTPGFIDLQI
CEEEECCCCCCCHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEEE
NGCGGVQFNDHINAISICTLEKMQETNQFSGCTSFLPTLITSNNVLMQRAIEIMRIFLSK
ECCCCCEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
NKNQALGLHLEGPFLNSTKRGIHNPILIRCPTKEMINYLCENSDVIRKITLAPEQLDMTF
CCCCEEEEEECCCCCCCHHHCCCCCEEEECCHHHHHHHHHCCCCEEEEEECCCHHHHHHH
IQKLKKSGICVAIGHSNATYEQARFSFSYGVSFGTHLFNAMPPLIAREPGVIGAIFDVPE
HHHHHHCCCEEEECCCCCCHHHHEEEEEECCHHHHHHHHHCCCHHHCCCCCEEEEHHHHH
IYCSVIADGLHVHWANIRYAKKIKGDRLILVTDATSPAGSNKIRSRFLFSNKTIYHRNNI
HHHHHHHCCCEEEEECEEEEHHCCCCEEEEEECCCCCCCCHHHHHHEEECCCEEEECCCC
CEDSKGTLSGSTLTMIQAIKNSVKYAGIPLDEAVRMATLYPAKAIGMDHCLGSLEINKIA
CCCCCCCCCCCHHHHHHHHHHCCEECCCCHHHHHHHHHCCCHHHCCHHHHCCCEEECCEE
NLTVFNTDYQIKKTIVNGKIVNTSLP
EEEEECCCCEEEEEEECCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]