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The map label for this gene is map [H]

Identifier: 71892052

GI number: 71892052

Start: 324077

End: 324859

Strand: Reverse

Name: map [H]

Synonym: BPEN_278

Alternate gene names: 71892052

Gene position: 324859-324077 (Counterclockwise)

Preceding gene: 71892071

Following gene: 229558494

Centisome position: 41.04

GC content: 32.57

Gene sequence:

>783_bases
ATGAAAATTATTATTAAAACGCTTACAGATATAGCAAAGATGCGCGTCTCTGGGAAGTTAGCTGCAGAAGTGTTAGAAAT
GATTGAAGCTTACGTGCAACCTGGTATTAGTACTGGAGAATTAGATACTATTTGCCATAATTATATTACACAAATACAAC
ATGCTATTTCTGCTCCTCTTGGTTATCATGGATTTCCTAAATCTATTTGTACCTCAATTAATGAGGTAGTTTGTCATGGT
ATTCCAAATAATTCACATAAATTAAAAGAAGGTGATATAATAAATATTGATATTACAGTAATTAAAGACGGATTATATGC
TGATACTTCTAGAATGTTTATTGTTGGTCGACCAACAAAGTTGGGGTATCGATTATGTAAGATCACTCAAGAAAGTCTTT
ATTTAGCAATTCGTATGATTAGACCAGGCATACGTTTAAAAAAAATAGGTCAATCTATCCAAAGATTTGTTGAAAGTCAA
AATTTTTCAATAGTAAGAGAGTATTGTGGGCATGGAATTGGAAAATTTTTTCACGAAGCTCCCCATGTATTGCATTATGA
TGCTGATGATGAAGGTGTGATATTAAAATCAGGCATGACATTAACAATAGAACCTATGGTAAATGCAGGTACTCGCCATA
TTTATACTGAAAATGACGGATGGACAGTAAAAACAAAAGATCATAATTTGTCAGCGCAGTATGAACACACTATTGTTGTT
ACAGAAAATGGGTGCGATGTATTAACGTTACGTTCCGATGAGTCTTTATCATCAATTATTTAA

Upstream 100 bases:

>100_bases
TAATTTATCTCCATTAGTGCAATGATTTGTGTATGTAAATCATATGATGTAAAGGCAAAAATATTATGTATTTGTTAATA
AAATTAATAATATATATATT

Downstream 100 bases:

>100_bases
ATCATTATAATTAATAAAAAAGGTATGTGTTTTATTGCCAATCATTTTTAGAGATACTTGCATTTATATTAATAAATGAC
TTTGAATAAGTACAAAAATA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKIIIKTLTDIAKMRVSGKLAAEVLEMIEAYVQPGISTGELDTICHNYITQIQHAISAPLGYHGFPKSICTSINEVVCHG
IPNNSHKLKEGDIINIDITVIKDGLYADTSRMFIVGRPTKLGYRLCKITQESLYLAIRMIRPGIRLKKIGQSIQRFVESQ
NFSIVREYCGHGIGKFFHEAPHVLHYDADDEGVILKSGMTLTIEPMVNAGTRHIYTENDGWTVKTKDHNLSAQYEHTIVV
TENGCDVLTLRSDESLSSII

Sequences:

>Translated_260_residues
MKIIIKTLTDIAKMRVSGKLAAEVLEMIEAYVQPGISTGELDTICHNYITQIQHAISAPLGYHGFPKSICTSINEVVCHG
IPNNSHKLKEGDIINIDITVIKDGLYADTSRMFIVGRPTKLGYRLCKITQESLYLAIRMIRPGIRLKKIGQSIQRFVESQ
NFSIVREYCGHGIGKFFHEAPHVLHYDADDEGVILKSGMTLTIEPMVNAGTRHIYTENDGWTVKTKDHNLSAQYEHTIVV
TENGCDVLTLRSDESLSSII
>Mature_260_residues
MKIIIKTLTDIAKMRVSGKLAAEVLEMIEAYVQPGISTGELDTICHNYITQIQHAISAPLGYHGFPKSICTSINEVVCHG
IPNNSHKLKEGDIINIDITVIKDGLYADTSRMFIVGRPTKLGYRLCKITQESLYLAIRMIRPGIRLKKIGQSIQRFVESQ
NFSIVREYCGHGIGKFFHEAPHVLHYDADDEGVILKSGMTLTIEPMVNAGTRHIYTENDGWTVKTKDHNLSAQYEHTIVV
TENGCDVLTLRSDESLSSII

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=254, Percent_Identity=42.5196850393701, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI40385867, Length=254, Percent_Identity=37.007874015748, Blast_Score=180, Evalue=9e-46,
Organism=Escherichia coli, GI1786364, Length=260, Percent_Identity=69.2307692307692, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=42.6294820717131, Blast_Score=217, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=43.3070866141732, Blast_Score=223, Evalue=3e-59,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=42.2924901185771, Blast_Score=212, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=41.2244897959184, Blast_Score=194, Evalue=4e-50,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29042; Mature: 29042

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIKTLTDIAKMRVSGKLAAEVLEMIEAYVQPGISTGELDTICHNYITQIQHAISAPL
CEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GYHGFPKSICTSINEVVCHGIPNNSHKLKEGDIINIDITVIKDGLYADTSRMFIVGRPTK
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEECCCCEEEEECCHH
LGYRLCKITQESLYLAIRMIRPGIRLKKIGQSIQRFVESQNFSIVREYCGHGIGKFFHEA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHC
PHVLHYDADDEGVILKSGMTLTIEPMVNAGTRHIYTENDGWTVKTKDHNLSAQYEHTIVV
CCEEEECCCCCCEEEECCCEEEEEECCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEEE
TENGCDVLTLRSDESLSSII
ECCCCCEEEEECCCHHHHCC
>Mature Secondary Structure
MKIIIKTLTDIAKMRVSGKLAAEVLEMIEAYVQPGISTGELDTICHNYITQIQHAISAPL
CEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GYHGFPKSICTSINEVVCHGIPNNSHKLKEGDIINIDITVIKDGLYADTSRMFIVGRPTK
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEECCCCEEEEECCHH
LGYRLCKITQESLYLAIRMIRPGIRLKKIGQSIQRFVESQNFSIVREYCGHGIGKFFHEA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHC
PHVLHYDADDEGVILKSGMTLTIEPMVNAGTRHIYTENDGWTVKTKDHNLSAQYEHTIVV
CCEEEECCCCCCEEEECCCEEEEEECCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEEE
TENGCDVLTLRSDESLSSII
ECCCCCEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]