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The map label for this gene is gapX [H]

Identifier: 68535959

GI number: 68535959

Start: 1055482

End: 1056948

Strand: Direct

Name: gapX [H]

Synonym: jk0882

Alternate gene names: 68535959

Gene position: 1055482-1056948 (Clockwise)

Preceding gene: 68535955

Following gene: 68535962

Centisome position: 42.86

GC content: 63.39

Gene sequence:

>1467_bases
ATGACCGACAACGCACACACCAAGAGCGCTCTGCACAGCGATTGGAACGAGCGGCTGGCCCTGGCGCAGGAGATGCTGCC
GCTGATCAGCCGCCTGCACCGCGACAAGAACGTGGTGACTTCCATCTTCGGCCGGCTGCTTGTCAACGTCACCGATATTG
ACATCATCAAGTCCCACCGCTACGCCCGCCGTGTGGTGGAAAAGGAGCTGCCGCTGGAGCAGACCCTGCCCGTGCTGCGC
GAGCTGGTGGAGATGGACCTGGGCACTGCCTCCATCGACATTGGATCCCTGGCCAGCCGCTACAACAAGGACTCCGAGGG
GCTGACCCTGCGCGAGTACCTGGAGCGCGAGCTGGCGGAGGTCATCGGCGGCCCGGAGCAGGTCGAGCCCCGCGACATCG
TCCTCTATGGCTTCGGCCGCATCGGCCGCCTGCTGGCCCGCATCCTGGTTGCCCGCGAGGCCACCTATGGCGGTGCGCGC
CTGCGTGCCGTCGTCGTCCGCTCCAAGGGTGAGGGCGACCTGATCAAGCGTGCTTCTCTGCTGCGCCGCGATTCCGTTCA
CGGAGCCTTCGACGGCACCATCACCACGGATGAGGAAAACAACACGATCTGGGCCAACGGCACCCCGATCCGCATTATCT
ACGCCAACAACCCGGCGGAGATCGACTACACCGAATACGGCATCAACGACGCAATCGTGGTGGACAACACTGGCGTGTGG
CGCGACCGGGACGGCCTGTCTCAGCACCTGGAGGCCAAGGGTGTGGCCAAGGTCCTGCTGACCGCTCCGGGCAAGGGCGA
CATCAAGAACATCGTCTACGGCATCAACCACGGCGACATCACTGAGGATGATCGCATTCTGTCTGCGGCGTCCTGTACTA
CCAACGGCATCACCCCGGTGCTGAAGGTCATCAACGACCGCTACGGCGTGGAGCACGGCCACGTGGAGACCGTGCACTCC
TTCACCAACGATCAGAACCTAATCGATAACTTCCACAAGGGCGACCGTCGTGGTCGCGCTGCGGGCCTGAACATGGTGCT
CACCGCCACGGGCGCGGCGAAGGCCGTTGCCAAGGCTCTGCCGGAGTTCGCGGGCAAGCTGACGGGTAACGCTATTCGCG
TGCCTACCCCGGACGTCTCCATGGCAGTGCTGAACCTGACCCTGAACCAGGATGTTGAGGCCGACGAGGTAAACAACTTC
CTGCGCCGTGTCTCCCTGCACTCCACGCTGCGCCAGCAGATCGACTTCATTAAGTCCCCGGAGGTCGTCTCCACCGACTT
CGTTGGTACTACCCACGCGGGCATCGTTGACGGTCTGGCCACCATCGCCAATGGCAACCACCTGGTGCTGTACGTCTGGT
ACGACAATGAGTTCGGCTACTCGAACCAGGTGATCCGCATTGTTGAGGAGATCGCCGGCGTGCGTCCGCGCGTGCTGCCG
CAGCGTGCCGCTGCGCAGGACCTGTAA

Upstream 100 bases:

>100_bases
AGCGGGTGTAAGCGTGGGGGCAACTAGACTTCAGGGGGTAAGAGGGTAACCCCCCGGATATTCGCAAAACGATTACTTCC
AGTGAGGTAGTGAGGTATAG

Downstream 100 bases:

>100_bases
TAGGGGTTAGCTCTATGGCTGGTGCTGGGTTATAGCAGCATCAGCAGGAGCATCTGGCAGCCGATGATCTTGCCGATCAT
CGCTGCCGGATAGACGGTGG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTDNAHTKSALHSDWNERLALAQEMLPLISRLHRDKNVVTSIFGRLLVNVTDIDIIKSHRYARRVVEKELPLEQTLPVLR
ELVEMDLGTASIDIGSLASRYNKDSEGLTLREYLERELAEVIGGPEQVEPRDIVLYGFGRIGRLLARILVAREATYGGAR
LRAVVVRSKGEGDLIKRASLLRRDSVHGAFDGTITTDEENNTIWANGTPIRIIYANNPAEIDYTEYGINDAIVVDNTGVW
RDRDGLSQHLEAKGVAKVLLTAPGKGDIKNIVYGINHGDITEDDRILSAASCTTNGITPVLKVINDRYGVEHGHVETVHS
FTNDQNLIDNFHKGDRRGRAAGLNMVLTATGAAKAVAKALPEFAGKLTGNAIRVPTPDVSMAVLNLTLNQDVEADEVNNF
LRRVSLHSTLRQQIDFIKSPEVVSTDFVGTTHAGIVDGLATIANGNHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVLP
QRAAAQDL

Sequences:

>Translated_488_residues
MTDNAHTKSALHSDWNERLALAQEMLPLISRLHRDKNVVTSIFGRLLVNVTDIDIIKSHRYARRVVEKELPLEQTLPVLR
ELVEMDLGTASIDIGSLASRYNKDSEGLTLREYLERELAEVIGGPEQVEPRDIVLYGFGRIGRLLARILVAREATYGGAR
LRAVVVRSKGEGDLIKRASLLRRDSVHGAFDGTITTDEENNTIWANGTPIRIIYANNPAEIDYTEYGINDAIVVDNTGVW
RDRDGLSQHLEAKGVAKVLLTAPGKGDIKNIVYGINHGDITEDDRILSAASCTTNGITPVLKVINDRYGVEHGHVETVHS
FTNDQNLIDNFHKGDRRGRAAGLNMVLTATGAAKAVAKALPEFAGKLTGNAIRVPTPDVSMAVLNLTLNQDVEADEVNNF
LRRVSLHSTLRQQIDFIKSPEVVSTDFVGTTHAGIVDGLATIANGNHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVLP
QRAAAQDL
>Mature_487_residues
TDNAHTKSALHSDWNERLALAQEMLPLISRLHRDKNVVTSIFGRLLVNVTDIDIIKSHRYARRVVEKELPLEQTLPVLRE
LVEMDLGTASIDIGSLASRYNKDSEGLTLREYLERELAEVIGGPEQVEPRDIVLYGFGRIGRLLARILVAREATYGGARL
RAVVVRSKGEGDLIKRASLLRRDSVHGAFDGTITTDEENNTIWANGTPIRIIYANNPAEIDYTEYGINDAIVVDNTGVWR
DRDGLSQHLEAKGVAKVLLTAPGKGDIKNIVYGINHGDITEDDRILSAASCTTNGITPVLKVINDRYGVEHGHVETVHSF
TNDQNLIDNFHKGDRRGRAAGLNMVLTATGAAKAVAKALPEFAGKLTGNAIRVPTPDVSMAVLNLTLNQDVEADEVNNFL
RRVSLHSTLRQQIDFIKSPEVVSTDFVGTTHAGIVDGLATIANGNHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVLPQ
RAAAQDL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=37.2781065088757, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=36.7469879518072, Blast_Score=185, Evalue=9e-47,
Organism=Escherichia coli, GI1789295, Length=347, Percent_Identity=34.5821325648415, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=36.6863905325444, Blast_Score=192, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=37.4269005847953, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=37.4269005847953, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=37.719298245614, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=37.719298245614, Blast_Score=194, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6322409, Length=342, Percent_Identity=38.3040935672515, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321631, Length=342, Percent_Identity=37.719298245614, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322468, Length=342, Percent_Identity=38.0116959064327, Blast_Score=207, Evalue=3e-54,
Organism=Drosophila melanogaster, GI85725000, Length=339, Percent_Identity=38.3480825958702, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI22023983, Length=339, Percent_Identity=38.3480825958702, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI17933600, Length=339, Percent_Identity=37.4631268436578, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18110149, Length=339, Percent_Identity=37.4631268436578, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=35.0299401197605, Blast_Score=180, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 53753; Mature: 53621

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNAHTKSALHSDWNERLALAQEMLPLISRLHRDKNVVTSIFGRLLVNVTDIDIIKSHR
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YARRVVEKELPLEQTLPVLRELVEMDLGTASIDIGSLASRYNKDSEGLTLREYLERELAE
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHH
VIGGPEQVEPRDIVLYGFGRIGRLLARILVAREATYGGARLRAVVVRSKGEGDLIKRASL
HHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHH
LRRDSVHGAFDGTITTDEENNTIWANGTPIRIIYANNPAEIDYTEYGINDAIVVDNTGVW
HHHHCCCCCCCCCEECCCCCCEEEECCCEEEEEECCCCCCCCCHHCCCCCEEEECCCCCC
RDRDGLSQHLEAKGVAKVLLTAPGKGDIKNIVYGINHGDITEDDRILSAASCTTNGITPV
CCCHHHHHHHHHCCCEEEEEECCCCCCCCHHEEECCCCCCCCCCHHEEHHCCCCCCHHHH
LKVINDRYGVEHGHVETVHSFTNDQNLIDNFHKGDRRGRAAGLNMVLTATGAAKAVAKAL
HHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHH
PEFAGKLTGNAIRVPTPDVSMAVLNLTLNQDVEADEVNNFLRRVSLHSTLRQQIDFIKSP
HHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVVSTDFVGTTHAGIVDGLATIANGNHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVLP
CEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
QRAAAQDL
CHHHHCCC
>Mature Secondary Structure 
TDNAHTKSALHSDWNERLALAQEMLPLISRLHRDKNVVTSIFGRLLVNVTDIDIIKSHR
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YARRVVEKELPLEQTLPVLRELVEMDLGTASIDIGSLASRYNKDSEGLTLREYLERELAE
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHH
VIGGPEQVEPRDIVLYGFGRIGRLLARILVAREATYGGARLRAVVVRSKGEGDLIKRASL
HHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHH
LRRDSVHGAFDGTITTDEENNTIWANGTPIRIIYANNPAEIDYTEYGINDAIVVDNTGVW
HHHHCCCCCCCCCEECCCCCCEEEECCCEEEEEECCCCCCCCCHHCCCCCEEEECCCCCC
RDRDGLSQHLEAKGVAKVLLTAPGKGDIKNIVYGINHGDITEDDRILSAASCTTNGITPV
CCCHHHHHHHHHCCCEEEEEECCCCCCCCHHEEECCCCCCCCCCHHEEHHCCCCCCHHHH
LKVINDRYGVEHGHVETVHSFTNDQNLIDNFHKGDRRGRAAGLNMVLTATGAAKAVAKAL
HHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHH
PEFAGKLTGNAIRVPTPDVSMAVLNLTLNQDVEADEVNNFLRRVSLHSTLRQQIDFIKSP
HHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EVVSTDFVGTTHAGIVDGLATIANGNHLVLYVWYDNEFGYSNQVIRIVEEIAGVRPRVLP
CEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCC
QRAAAQDL
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680173 [H]