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The map label for this gene is cmk [H]

Identifier: 68535955

GI number: 68535955

Start: 1047808

End: 1050141

Strand: Direct

Name: cmk [H]

Synonym: jk0878

Alternate gene names: 68535955

Gene position: 1047808-1050141 (Clockwise)

Preceding gene: 68535954

Following gene: 68535959

Centisome position: 42.55

GC content: 65.64

Gene sequence:

>2334_bases
ATGACGAACGCACCTTTCTTCGAGCCAGGCTCCGCCCTGGATCAGCTCGCCAGTGCAAAGAACATTGAGGATGGCGGCCT
GATCGTCGCCGTCGACGGCCCAAGCGGCACCGGCAAGTCCACCGTCTGCCGCCGCCTGGCCACCGCCGCGGACGCGAAGT
ACTTGGATACCGGCGCTATGTACCGCGTCGCCACGCTGCATGTTCTGCGCCAGGGCATCGATCCTTCCGAGGAGTCCGCA
CGCGAGGCGATCATCGCCGCCACCGCCGACCTGCCCCTGGAAATCAACGAGGATCCTACCTCTACCGAGGTGCTGCTGGA
CGGCACCGACGTTTCCGGCGAGATCCGCGGCCCGGAGGTCACCGCGCACGTCTCCGCTGTCGCCGCCATCCCGGAGGTGC
GCGAGAACCTAGTCGCACTGCAGCGCTCTCTGGCCTTCGCCGCCGGTCGCTGCGTGGTCGAGGGCCGCGACATCGGAACT
GTGGTTCTTTCGGACGCCCCAGTGAAGATCTTCATGACCGCCTCCGCCGAGGTGCGGGCCCAGCGCCGATACGATCAGGA
TCTGGAAGCTGGCCGAGAGGCGGACTACGAGGCTGTACTCGCGGATGTGCAGCGCCGTGATGAGGCCGACTCCTCCCGTA
AGACCTCTCCGCTCCGCCCGGCAGAGGACGCTGTGATTGTGGATACCGGCGAGATGGACATCGACGAAGTGCTGGAGAAG
CTGGCGCAGCTGACCCTGGCAAGCGCCAAGCCGGACAGCCTGGATTCCCCCGAAGAGCTGGTTTTCCGCACGGCTGATGG
CGAGGTTCTGGGGGAGTCCGACTTCTCCGCCGTCGAGTTCTCCGAGTACGACGATGACGAGTTCGACGAGGGCAACGAGT
CCAGCCCCGAGGAGTTCTTCATCACCGGCCCGGATGACTTCACCCTCGAGGGTGGCGGCGACATGCCGGAATCCGACGAG
GATTGGGAAGCCCTGGAGGAGGCTTTCGGCGTACTCGGTGACGAGGAGGCCGAACAGGAGGCCCTGTGCACCGTCGCCAT
CGTCGGCCGTCCGAACGTGGGCAAGTCCACCCTGGTGAACCGCTTCATCGGCCGTCGCGAGGCCGTGGTGGAGGACTTCC
CGGGTGTCACCCGCGACCGCATTTCCTACCTGGGCGAGTGGTCCGGCCGCCGCTTCTGGGTGCAGGATACGGGCGGCTGG
GATCCGGATGCGAAGGGCATCCACGCGGCCATCGCCCGCCAGGCGGAGACTGCCATGGAGACCGCCGATGTGATCGTCTT
CGTGGTCGACTCGAAGGTCGGCATCACCTCCACCGACGAGGTCATCGCCCGCAAGCTGCAGCGCAGTAAGGTGCCCGTGA
TCGTGGTCGCCAACAAGTGCGATGCGGACGCACAGTTGGGCGACGTCGCCGAGTTCTGGGCACTGGGCCTGGATAACCCA
TACCCGGTGTCCGCGCAGCACGGCAAGGGCGCGGCGGACGTTATGGACGAGGTCCTGCGCGTCTTCCCGGAGCACCCGCG
CGAGCTCTCCGTCGTTTCCGGCCCGCGCCGTGTGGCCCTGGTCGGCCGCCCGAACGTGGGCAAGTCCTCTCTGCTGAACA
AGATCACGGGCGAGGAGCGCTCCGTGGTCAACAACGTTGCAGGCACCACTGTCGACCCGGTCGACTCCATCGTGGAGCTG
GAGGAAAAGACCTGGAAGTTTGTGGATACCGCCGGCATTCGCAAGAAGACGAAGCAAGCGCGCGGCCACGAGTTCTACGC
CTCGCTGCGCACCCGTTCCGCCATCGACGCGGCGGAGGTCGTTGTTTTTCTTGTTGACGCCAGCGAGCCCATCGCCGAGC
AGGATCAGCGAGTGCTTCGCATGATCCTCGACTCGGGGCGTGCCCTGGTAGTGGCCTACAACAAGTGGGACCTGGTGGAT
GAGGACCGCCGTGAGCTGCTGGAGCGGGAGATCGAGCTGCAGCTTTCCCACGTACCATGGGCCCGCCGCGTGAATATTTC
CGCCAAGACCGGCCGCGCGCTGCAGAAACTGGAGCCCGCGATGATCGAGGCTTTGGAGAGCTGGGATCAGCGCATCTCCA
CCGGTCAGCTGAATACCTGGCTGCGTGCAGTGATCGCGGAGACCCCGCCGCCGATGCGTGGCGGCCGCCTGCCACGCGTG
CTGTTTGCCACCCAGGCTTCCACCAAGCCGCCGGTGATTGTGCTGTTCACCACCGGCTTCCTGGAGCACGGCTACCGCCG
CTTTTTGGAGCGCAAGCTGCGTGAATCCTTCGGCTTCGAGGGCTCGCCGGTACGCATCGCAGTGCGCGTGCGCGAGAAGA
AGCGTAAGAAGTAG

Upstream 100 bases:

>100_bases
GCACTGAACCAGGCGGAACTGCAGAGCATGTACAAGAAGGTCGGGCTGTAGCTAGATCAGCCGACGTAAACACACAATCA
ATTAGGGGAACGACCTTTTT

Downstream 100 bases:

>100_bases
GCCTAGCGTCTACTTAGAGATTTAGCCTTTATGCTGCAAGAGCGCCAACGGTGGTCATATGATACGTATATGCCGGTCGG
AAAAATAGTTGAATCTAATT

Product: bifunctional cytidylate kinase/GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MTNAPFFEPGSALDQLASAKNIEDGGLIVAVDGPSGTGKSTVCRRLATAADAKYLDTGAMYRVATLHVLRQGIDPSEESA
REAIIAATADLPLEINEDPTSTEVLLDGTDVSGEIRGPEVTAHVSAVAAIPEVRENLVALQRSLAFAAGRCVVEGRDIGT
VVLSDAPVKIFMTASAEVRAQRRYDQDLEAGREADYEAVLADVQRRDEADSSRKTSPLRPAEDAVIVDTGEMDIDEVLEK
LAQLTLASAKPDSLDSPEELVFRTADGEVLGESDFSAVEFSEYDDDEFDEGNESSPEEFFITGPDDFTLEGGGDMPESDE
DWEALEEAFGVLGDEEAEQEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYLGEWSGRRFWVQDTGGW
DPDAKGIHAAIARQAETAMETADVIVFVVDSKVGITSTDEVIARKLQRSKVPVIVVANKCDADAQLGDVAEFWALGLDNP
YPVSAQHGKGAADVMDEVLRVFPEHPRELSVVSGPRRVALVGRPNVGKSSLLNKITGEERSVVNNVAGTTVDPVDSIVEL
EEKTWKFVDTAGIRKKTKQARGHEFYASLRTRSAIDAAEVVVFLVDASEPIAEQDQRVLRMILDSGRALVVAYNKWDLVD
EDRRELLEREIELQLSHVPWARRVNISAKTGRALQKLEPAMIEALESWDQRISTGQLNTWLRAVIAETPPPMRGGRLPRV
LFATQASTKPPVIVLFTTGFLEHGYRRFLERKLRESFGFEGSPVRIAVRVREKKRKK

Sequences:

>Translated_777_residues
MTNAPFFEPGSALDQLASAKNIEDGGLIVAVDGPSGTGKSTVCRRLATAADAKYLDTGAMYRVATLHVLRQGIDPSEESA
REAIIAATADLPLEINEDPTSTEVLLDGTDVSGEIRGPEVTAHVSAVAAIPEVRENLVALQRSLAFAAGRCVVEGRDIGT
VVLSDAPVKIFMTASAEVRAQRRYDQDLEAGREADYEAVLADVQRRDEADSSRKTSPLRPAEDAVIVDTGEMDIDEVLEK
LAQLTLASAKPDSLDSPEELVFRTADGEVLGESDFSAVEFSEYDDDEFDEGNESSPEEFFITGPDDFTLEGGGDMPESDE
DWEALEEAFGVLGDEEAEQEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYLGEWSGRRFWVQDTGGW
DPDAKGIHAAIARQAETAMETADVIVFVVDSKVGITSTDEVIARKLQRSKVPVIVVANKCDADAQLGDVAEFWALGLDNP
YPVSAQHGKGAADVMDEVLRVFPEHPRELSVVSGPRRVALVGRPNVGKSSLLNKITGEERSVVNNVAGTTVDPVDSIVEL
EEKTWKFVDTAGIRKKTKQARGHEFYASLRTRSAIDAAEVVVFLVDASEPIAEQDQRVLRMILDSGRALVVAYNKWDLVD
EDRRELLEREIELQLSHVPWARRVNISAKTGRALQKLEPAMIEALESWDQRISTGQLNTWLRAVIAETPPPMRGGRLPRV
LFATQASTKPPVIVLFTTGFLEHGYRRFLERKLRESFGFEGSPVRIAVRVREKKRKK
>Mature_776_residues
TNAPFFEPGSALDQLASAKNIEDGGLIVAVDGPSGTGKSTVCRRLATAADAKYLDTGAMYRVATLHVLRQGIDPSEESAR
EAIIAATADLPLEINEDPTSTEVLLDGTDVSGEIRGPEVTAHVSAVAAIPEVRENLVALQRSLAFAAGRCVVEGRDIGTV
VLSDAPVKIFMTASAEVRAQRRYDQDLEAGREADYEAVLADVQRRDEADSSRKTSPLRPAEDAVIVDTGEMDIDEVLEKL
AQLTLASAKPDSLDSPEELVFRTADGEVLGESDFSAVEFSEYDDDEFDEGNESSPEEFFITGPDDFTLEGGGDMPESDED
WEALEEAFGVLGDEEAEQEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYLGEWSGRRFWVQDTGGWD
PDAKGIHAAIARQAETAMETADVIVFVVDSKVGITSTDEVIARKLQRSKVPVIVVANKCDADAQLGDVAEFWALGLDNPY
PVSAQHGKGAADVMDEVLRVFPEHPRELSVVSGPRRVALVGRPNVGKSSLLNKITGEERSVVNNVAGTTVDPVDSIVELE
EKTWKFVDTAGIRKKTKQARGHEFYASLRTRSAIDAAEVVVFLVDASEPIAEQDQRVLRMILDSGRALVVAYNKWDLVDE
DRRELLEREIELQLSHVPWARRVNISAKTGRALQKLEPAMIEALESWDQRISTGQLNTWLRAVIAETPPPMRGGRLPRVL
FATQASTKPPVIVLFTTGFLEHGYRRFLERKLRESFGFEGSPVRIAVRVREKKRKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=454, Percent_Identity=36.5638766519824, Blast_Score=286, Evalue=4e-78,
Organism=Escherichia coli, GI1787139, Length=216, Percent_Identity=42.5925925925926, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI2367268, Length=196, Percent_Identity=28.0612244897959, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=193, Percent_Identity=25.3886010362694, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 85122; Mature: 84991

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAPFFEPGSALDQLASAKNIEDGGLIVAVDGPSGTGKSTVCRRLATAADAKYLDTGAM
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCHH
YRVATLHVLRQGIDPSEESAREAIIAATADLPLEINEDPTSTEVLLDGTDVSGEIRGPEV
HHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEE
TAHVSAVAAIPEVRENLVALQRSLAFAAGRCVVEGRDIGTVVLSDAPVKIFMTASAEVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEECCCCEEEEEECCHHHHH
QRRYDQDLEAGREADYEAVLADVQRRDEADSSRKTSPLRPAEDAVIVDTGEMDIDEVLEK
HHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
LAQLTLASAKPDSLDSPEELVFRTADGEVLGESDFSAVEFSEYDDDEFDEGNESSPEEFF
HHHHHHCCCCCCCCCCHHHHEEECCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCEE
ITGPDDFTLEGGGDMPESDEDWEALEEAFGVLGDEEAEQEALCTVAIVGRPNVGKSTLVN
EECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
RFIGRREAVVEDFPGVTRDRISYLGEWSGRRFWVQDTGGWDPDAKGIHAAIARQAETAME
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
TADVIVFVVDSKVGITSTDEVIARKLQRSKVPVIVVANKCDADAQLGDVAEFWALGLDNP
HCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
YPVSAQHGKGAADVMDEVLRVFPEHPRELSVVSGPRRVALVGRPNVGKSSLLNKITGEER
CCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCHH
SVVNNVAGTTVDPVDSIVELEEKTWKFVDTAGIRKKTKQARGHEFYASLRTRSAIDAAEV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
VVFLVDASEPIAEQDQRVLRMILDSGRALVVAYNKWDLVDEDRRELLEREIELQLSHVPW
EEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCC
ARRVNISAKTGRALQKLEPAMIEALESWDQRISTGQLNTWLRAVIAETPPPMRGGRLPRV
EEEEECCHHHCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEE
LFATQASTKPPVIVLFTTGFLEHGYRRFLERKLRESFGFEGSPVRIAVRVREKKRKK
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCCCC
>Mature Secondary Structure 
TNAPFFEPGSALDQLASAKNIEDGGLIVAVDGPSGTGKSTVCRRLATAADAKYLDTGAM
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCHH
YRVATLHVLRQGIDPSEESAREAIIAATADLPLEINEDPTSTEVLLDGTDVSGEIRGPEV
HHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCEEECCCCCCCEEEEECCCCCCCCCCCEE
TAHVSAVAAIPEVRENLVALQRSLAFAAGRCVVEGRDIGTVVLSDAPVKIFMTASAEVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCEEEECCCCEEEEEECCHHHHH
QRRYDQDLEAGREADYEAVLADVQRRDEADSSRKTSPLRPAEDAVIVDTGEMDIDEVLEK
HHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
LAQLTLASAKPDSLDSPEELVFRTADGEVLGESDFSAVEFSEYDDDEFDEGNESSPEEFF
HHHHHHCCCCCCCCCCHHHHEEECCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCEE
ITGPDDFTLEGGGDMPESDEDWEALEEAFGVLGDEEAEQEALCTVAIVGRPNVGKSTLVN
EECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
RFIGRREAVVEDFPGVTRDRISYLGEWSGRRFWVQDTGGWDPDAKGIHAAIARQAETAME
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
TADVIVFVVDSKVGITSTDEVIARKLQRSKVPVIVVANKCDADAQLGDVAEFWALGLDNP
HCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
YPVSAQHGKGAADVMDEVLRVFPEHPRELSVVSGPRRVALVGRPNVGKSSLLNKITGEER
CCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCHH
SVVNNVAGTTVDPVDSIVELEEKTWKFVDTAGIRKKTKQARGHEFYASLRTRSAIDAAEV
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
VVFLVDASEPIAEQDQRVLRMILDSGRALVVAYNKWDLVDEDRRELLEREIELQLSHVPW
EEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCC
ARRVNISAKTGRALQKLEPAMIEALESWDQRISTGQLNTWLRAVIAETPPPMRGGRLPRV
EEEEECCHHHCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEE
LFATQASTKPPVIVLFTTGFLEHGYRRFLERKLRESFGFEGSPVRIAVRVREKKRKK
EEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]