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The map label for this gene is ppnK

Identifier: 68535942

GI number: 68535942

Start: 1033433

End: 1034422

Strand: Direct

Name: ppnK

Synonym: jk0865

Alternate gene names: 68535942

Gene position: 1033433-1034422 (Clockwise)

Preceding gene: 68535941

Following gene: 68535943

Centisome position: 41.97

GC content: 64.34

Gene sequence:

>990_bases
GTGACCACACCGGGGACTGACCACAACGCGGATCAGGGCGCGGATTCTGGCGACAAGGCCACCAAGGCTGCTTCTGGCGC
ACAGACCGAACGTGAGGTTCTGCTTGTTGCGCACACCGGTGTGCACGAGAACTTGGGCCTGGCTGCAGAGGCGGCGTCCC
GTCTGCAAAAGGGCGGCATCAACGTTCGCGTGATGGCTACCGCCGACCCGGCTCCAGTGGCCCGTCATGAGGTTCTGGGG
CGTTTCAAGCGTTTCGGCCACACCAAGGAGGCCGCCACGGGCGTGGAGATGGTGATTGTTCTGGGCGGCGACGGTACCTT
CCTGCGCGCAGCCGACATCGCGCACTCGGCGGATGTTCCGGTGTTGGGCATCAACATGGGTCACATCGGCTTCCTTGCGG
AGTGGGAGCAGGAATCCCTGCAGGAGGCTGTGGACCGGGTGATCGACCGCGACTACCGCATCGAAGACCGCATGACCTTG
TCGATCACTGCCCGCGACATGGACGGTCGCGTTCTGGGCACGGGCTGGGCACTGAACGAGTGCTCCGTGGAGAACCTGAA
CCGCCAGGGCGTGCTGGATACGATCCTGGAGGTCGATGAGCGCCCTGTTTCTTCGTTCGGTTGTGACGGTGTTTTGGTAT
CGACGCCCACAGGCTCCACCGCCTATGCCTTCAGTGCAGGTGGCCCGGTTCTATGGCCGGAGTTGGATGCGATTTTGGTT
GTAACCAGCAACGCGCACACGCTATTTAGCCGCCCGCTGGTGGTCTCCCCGAACTCGATGGTGGCAGTGGAGACGAACCC
GTCGACCTCGCCTGCGACCGTGGTGATGGATGGTTTCCGTCAGATCCACATGCCCCCGGGCGCACGCGTGGAGATCCGCC
GCGGCCCGCAGCCGGTGCGCTGGGTGCGCCTGGATTCCGCGCCGTTTACCGACCGCCTGGTACACAAGTTCCGCTTGCCC
GTGACGGGCTGGAGGGGTCCGCGCCACTAG

Upstream 100 bases:

>100_bases
TGGTCAAGGACAGTGCTGCGGTTTCACCTAGCATGGTTGAAGAGGCTGACCACACCGGCCTGGACGAGATGATCGCAACC
GCTATTAAGGAGGGCCCGCA

Downstream 100 bases:

>100_bases
TAATGCTGCACGAACTACACATTCGCAACCTCGGTGTGATCGAGGAGGCGACGGCGGAGTTTTCCACGGGCTTGAGCGTT
GTCACCGGCGAGACCGGTGC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTTPGTDHNADQGADSGDKATKAASGAQTEREVLLVAHTGVHENLGLAAEAASRLQKGGINVRVMATADPAPVARHEVLG
RFKRFGHTKEAATGVEMVIVLGGDGTFLRAADIAHSADVPVLGINMGHIGFLAEWEQESLQEAVDRVIDRDYRIEDRMTL
SITARDMDGRVLGTGWALNECSVENLNRQGVLDTILEVDERPVSSFGCDGVLVSTPTGSTAYAFSAGGPVLWPELDAILV
VTSNAHTLFSRPLVVSPNSMVAVETNPSTSPATVVMDGFRQIHMPPGARVEIRRGPQPVRWVRLDSAPFTDRLVHKFRLP
VTGWRGPRH

Sequences:

>Translated_329_residues
MTTPGTDHNADQGADSGDKATKAASGAQTEREVLLVAHTGVHENLGLAAEAASRLQKGGINVRVMATADPAPVARHEVLG
RFKRFGHTKEAATGVEMVIVLGGDGTFLRAADIAHSADVPVLGINMGHIGFLAEWEQESLQEAVDRVIDRDYRIEDRMTL
SITARDMDGRVLGTGWALNECSVENLNRQGVLDTILEVDERPVSSFGCDGVLVSTPTGSTAYAFSAGGPVLWPELDAILV
VTSNAHTLFSRPLVVSPNSMVAVETNPSTSPATVVMDGFRQIHMPPGARVEIRRGPQPVRWVRLDSAPFTDRLVHKFRLP
VTGWRGPRH
>Mature_328_residues
TTPGTDHNADQGADSGDKATKAASGAQTEREVLLVAHTGVHENLGLAAEAASRLQKGGINVRVMATADPAPVARHEVLGR
FKRFGHTKEAATGVEMVIVLGGDGTFLRAADIAHSADVPVLGINMGHIGFLAEWEQESLQEAVDRVIDRDYRIEDRMTLS
ITARDMDGRVLGTGWALNECSVENLNRQGVLDTILEVDERPVSSFGCDGVLVSTPTGSTAYAFSAGGPVLWPELDAILVV
TSNAHTLFSRPLVVSPNSMVAVETNPSTSPATVVMDGFRQIHMPPGARVEIRRGPQPVRWVRLDSAPFTDRLVHKFRLPV
TGWRGPRH

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=315, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788968, Length=253, Percent_Identity=31.2252964426877, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=28.099173553719, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322509, Length=223, Percent_Identity=27.3542600896861, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325068, Length=214, Percent_Identity=25.7009345794392, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_CORJK (Q4JVX8)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250647.1
- ProteinModelPortal:   Q4JVX8
- SMR:   Q4JVX8
- STRING:   Q4JVX8
- GeneID:   3432972
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0865
- NMPDR:   fig|306537.3.peg.5
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   CVPEGFD
- ProtClustDB:   PRK03372
- BioCyc:   CJEI306537:JK0865-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 35390; Mature: 35259

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPGTDHNADQGADSGDKATKAASGAQTEREVLLVAHTGVHENLGLAAEAASRLQKGGI
CCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCC
NVRVMATADPAPVARHEVLGRFKRFGHTKEAATGVEMVIVLGGDGTFLRAADIAHSADVP
EEEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCCCCC
VLGINMGHIGFLAEWEQESLQEAVDRVIDRDYRIEDRMTLSITARDMDGRVLGTGWALNE
EEEECCCCCCEEEHHHHHHHHHHHHHHHCCCCEECCEEEEEEEEECCCCEEEECCEECCC
CSVENLNRQGVLDTILEVDERPVSSFGCDGVLVSTPTGSTAYAFSAGGPVLWPELDAILV
CCHHCCCCCCHHHHHHHCCCCCCHHCCCCEEEEECCCCCEEEEEECCCCEECCCCCEEEE
VTSNAHTLFSRPLVVSPNSMVAVETNPSTSPATVVMDGFRQIHMPPGARVEIRRGPQPVR
EECCCHHHHCCCEEECCCCEEEEECCCCCCCCEEEEECCCEECCCCCCEEEECCCCCCEE
WVRLDSAPFTDRLVHKFRLPVTGWRGPRH
EEEECCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTPGTDHNADQGADSGDKATKAASGAQTEREVLLVAHTGVHENLGLAAEAASRLQKGGI
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCC
NVRVMATADPAPVARHEVLGRFKRFGHTKEAATGVEMVIVLGGDGTFLRAADIAHSADVP
EEEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCCCCEEEEECCCCCCCCC
VLGINMGHIGFLAEWEQESLQEAVDRVIDRDYRIEDRMTLSITARDMDGRVLGTGWALNE
EEEECCCCCCEEEHHHHHHHHHHHHHHHCCCCEECCEEEEEEEEECCCCEEEECCEECCC
CSVENLNRQGVLDTILEVDERPVSSFGCDGVLVSTPTGSTAYAFSAGGPVLWPELDAILV
CCHHCCCCCCHHHHHHHCCCCCCHHCCCCEEEEECCCCCEEEEEECCCCEECCCCCEEEE
VTSNAHTLFSRPLVVSPNSMVAVETNPSTSPATVVMDGFRQIHMPPGARVEIRRGPQPVR
EECCCHHHHCCCEEECCCCEEEEECCCCCCCCEEEEECCCEECCCCCCEEEECCCCCCEE
WVRLDSAPFTDRLVHKFRLPVTGWRGPRH
EEEECCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA