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The map label for this gene is impA [H]

Identifier: 68535867

GI number: 68535867

Start: 945922

End: 946899

Strand: Direct

Name: impA [H]

Synonym: jk0792

Alternate gene names: 68535867

Gene position: 945922-946899 (Clockwise)

Preceding gene: 68535866

Following gene: 68535868

Centisome position: 38.41

GC content: 67.18

Gene sequence:

>978_bases
ATGACGGCCTTCCACGGACTGCCCCCGGAGGAACTGGATACCCGCTCGCTGCTGGCCATCGCCGAGGCGGCGGTGGACGA
AGCCGAGACGACGTTTACGGCCGCCGTCGGCGCGGAACCGGAGGTCATCAAGTCCCCCGGTGACTTCGCCACCGAGGCGG
ACCTGAGCGTCGAGCGCCAGCTGCGCACGCTGCTGACGCAATACACCGGCCTGCCCGTGCACGGCGAGGAGTTTGGCACG
GTGCGCCCCGGTGAGATCCCGGGGGAGAACATCACCGAGCCGAACCCTAATGACGCGATGGCGGACGGCCTGGACGGCCC
GCGCCGCAAGTCTCTCGAAGCCGGGGACCAGGAACTGCCGGAGACCTTCTGGGTGGTGGACCCCATCGACGGCACAGCCA
ACTACGCGGTGGGCAATCCTTTTGCCTGCATCCTCGTTTCCTTGGTGCACCAGGGGCAGACCATGGTCTCCGTCACCGAG
ATGCCGCTGCTGGGCAAGCGCATCACTGCTCGACGTGGCGAGGGGCTGCTGGTGGACGGGCACCCGGCCCGCGCCATGCC
GCCGTCGGATCCGGGCGTGACGCAGATCAGCTTCGGTTCCATCCTGTCGCAGCGCCGTGGTAACCTGCCAATTTCTTATC
GTCAGGACATGCTGAACGAGATCGGAAAGTCCTACCCGCGCATGCGCGTCACCGGCTCGGTGGGCATCGACCTGGCATTC
ACCGCTGCCGGAGTGTTCGGCGGCACTGTCACCTTCAGCCCTAACCTGTGGGACAACGCGGCGGGCATCCTCGCCGTGGA
GGAAAACGGTGGCGTTGCCACCGACTTCGCTGGCAACCCGTGGCGTCCGGGCGTTTCCGGCCTGGTCGCGGGCGAGCCGG
AGGTGCACGCCACGCTCCTGCAGCACATTCAGGCCGTGCCGATTGGTACTGCCGCCCGCAACGCCCAGGAGATTCGCGAC
CGAGGAGGCATTCGATGA

Upstream 100 bases:

>100_bases
TGGACTCCGCGATCGTGGGCAAGGCCCTGTATGCGGGTAAGTTCACCCTGGAGGAGGCTCTGGAAGCGGCTCAGGGAGTG
GCAAGGGGGAGCGACATCTA

Downstream 100 bases:

>100_bases
GTGTTACCGTGCGCGTCATTCCGTGCCTGGATGTGGACAACGGCCGCGTTGTCAAGGGCGTGAACTTCGAGGGCCTGCGC
GATGCAGGCGACCCCGTCGA

Product: inositol monophosphate phosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTAFHGLPPEELDTRSLLAIAEAAVDEAETTFTAAVGAEPEVIKSPGDFATEADLSVERQLRTLLTQYTGLPVHGEEFGT
VRPGEIPGENITEPNPNDAMADGLDGPRRKSLEAGDQELPETFWVVDPIDGTANYAVGNPFACILVSLVHQGQTMVSVTE
MPLLGKRITARRGEGLLVDGHPARAMPPSDPGVTQISFGSILSQRRGNLPISYRQDMLNEIGKSYPRMRVTGSVGIDLAF
TAAGVFGGTVTFSPNLWDNAAGILAVEENGGVATDFAGNPWRPGVSGLVAGEPEVHATLLQHIQAVPIGTAARNAQEIRD
RGGIR

Sequences:

>Translated_325_residues
MTAFHGLPPEELDTRSLLAIAEAAVDEAETTFTAAVGAEPEVIKSPGDFATEADLSVERQLRTLLTQYTGLPVHGEEFGT
VRPGEIPGENITEPNPNDAMADGLDGPRRKSLEAGDQELPETFWVVDPIDGTANYAVGNPFACILVSLVHQGQTMVSVTE
MPLLGKRITARRGEGLLVDGHPARAMPPSDPGVTQISFGSILSQRRGNLPISYRQDMLNEIGKSYPRMRVTGSVGIDLAF
TAAGVFGGTVTFSPNLWDNAAGILAVEENGGVATDFAGNPWRPGVSGLVAGEPEVHATLLQHIQAVPIGTAARNAQEIRD
RGGIR
>Mature_324_residues
TAFHGLPPEELDTRSLLAIAEAAVDEAETTFTAAVGAEPEVIKSPGDFATEADLSVERQLRTLLTQYTGLPVHGEEFGTV
RPGEIPGENITEPNPNDAMADGLDGPRRKSLEAGDQELPETFWVVDPIDGTANYAVGNPFACILVSLVHQGQTMVSVTEM
PLLGKRITARRGEGLLVDGHPARAMPPSDPGVTQISFGSILSQRRGNLPISYRQDMLNEIGKSYPRMRVTGSVGIDLAFT
AAGVFGGTVTFSPNLWDNAAGILAVEENGGVATDFAGNPWRPGVSGLVAGEPEVHATLLQHIQAVPIGTAARNAQEIRDR
GGIR

Specific function: Catalyzes the dephosphorylation of inositol-1-phosphate (I-1-P) to yield free myo-inositol, a key metabolite in mycobacteria [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788882, Length=196, Percent_Identity=31.6326530612245, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193202572, Length=161, Percent_Identity=31.6770186335404, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193202570, Length=161, Percent_Identity=31.055900621118, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357329, Length=160, Percent_Identity=30, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21357303, Length=162, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357957, Length=162, Percent_Identity=29.0123456790123, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 34438; Mature: 34307

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFHGLPPEELDTRSLLAIAEAAVDEAETTFTAAVGAEPEVIKSPGDFATEADLSVERQ
CCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCHHHHHH
LRTLLTQYTGLPVHGEEFGTVRPGEIPGENITEPNPNDAMADGLDGPRRKSLEAGDQELP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCCHHCC
ETFWVVDPIDGTANYAVGNPFACILVSLVHQGQTMVSVTEMPLLGKRITARRGEGLLVDG
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHCHHHHHCCCCEEEECC
HPARAMPPSDPGVTQISFGSILSQRRGNLPISYRQDMLNEIGKSYPRMRVTGSVGIDLAF
CCCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
TAAGVFGGTVTFSPNLWDNAAGILAVEENGGVATDFAGNPWRPGVSGLVAGEPEVHATLL
HHHHHCCCEEEECCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCEECCCCHHHHHHH
QHIQAVPIGTAARNAQEIRDRGGIR
HHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAFHGLPPEELDTRSLLAIAEAAVDEAETTFTAAVGAEPEVIKSPGDFATEADLSVERQ
CCCCCCCHHHHCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCHHHHHH
LRTLLTQYTGLPVHGEEFGTVRPGEIPGENITEPNPNDAMADGLDGPRRKSLEAGDQELP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCCHHCC
ETFWVVDPIDGTANYAVGNPFACILVSLVHQGQTMVSVTEMPLLGKRITARRGEGLLVDG
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHCHHHHHCCCCEEEECC
HPARAMPPSDPGVTQISFGSILSQRRGNLPISYRQDMLNEIGKSYPRMRVTGSVGIDLAF
CCCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
TAAGVFGGTVTFSPNLWDNAAGILAVEENGGVATDFAGNPWRPGVSGLVAGEPEVHATLL
HHHHHCCCEEEECCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCEECCCCHHHHHHH
QHIQAVPIGTAARNAQEIRDRGGIR
HHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]