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The map label for this gene is nadA [H]

Identifier: 68535858

GI number: 68535858

Start: 936545

End: 937573

Strand: Direct

Name: nadA [H]

Synonym: jk0783

Alternate gene names: 68535858

Gene position: 936545-937573 (Clockwise)

Preceding gene: 68535857

Following gene: 68535859

Centisome position: 38.03

GC content: 65.6

Gene sequence:

>1029_bases
ATGCTTAACAAAACCATAGAGAGTATCAGTCGCGTGGATGGCCTCTGGACCTTGCCGGATGGCATCTCCACCGACGAGTG
GGCCGCGGAAGTTCGCCGGCTGAAGGAAGAGAAGAATGCGCTGATCCTGGCGCATAACTACCAGCTACCGGAGATCCAGG
ACATCGCCGACCATACCGGCGATTCCCTCGCGCTGTCGCGCATCGCGGCGGAGACGGACGCCGACGTGATCGTTTTCTGC
GGCGTGCACTTTATGGCCGAGACGGCGAAGATCCTGTCGCCGGAAAAGACTGTTCTTATTCCTGACGCCAACGCGGGGTG
CTCCCTGGCCGATTCCCTTACAGCCGACGAGCTGCGTGAGTGGAAGGCCGAGCACCCGGGGGCCGTGGTGGTCAGCTACG
TGAACACCACCGCCGATGTGAAGGCCCTGACGGACATCTGCTGCACCAGCTCCAACGCGGTGGACGTGGTGGCCAGCCTG
CCGGAGGATCAGGAGGTGCTGTTTGGCCCCGACCAGTTCCTCGGCGCTCACGTGCGCCGCGAGACCGGGCGGGACAACAT
CCACGTCTGGGCAGGCGAGTGCCACGTGCACGCCGGCATCTCTGGCCAGGAGCTGAGCCAGCAGGCGCACGATAACCCGA
CGGCGGATCTGTTTATCCACCCGGAGTGCGGCTGCGCCAACTCCGCCATCTACCTGGCGGGCGAGGGCATTGTGGAGCCG
GAGCGGGTGAAGATGCTCTCCACCGGCGACATGATCTCGCAGGCCAAGTCCACCAACCAGTCCACCGTGCTGGTCGCCAC
CGAGGTCGGCATGCTGCACCAGCTGCGCCAGGCCAACCCGGAGGTGGACTTCCGCGCCGTGAACGACCGGGCGGCCTGCA
CGTACATGAAGATGATCACCCCGGCGGCCCTGCTGCGCTGCCTGGCGCTGGGCGAGGACGAGGTGACGGTGGACGAGGAG
ACCGCCGCAGCGGCCCGTCGTTCCGTGGAGCGCATGATCGCCATCGGCAACCCGGGAAGCGGGGAGTAG

Upstream 100 bases:

>100_bases
ATTTCGGCGACCTTCGCGGACCCGGAGGACTTTGAAGACTAGCCGGGGACTTTAGGCAGAAACGCGCTGCTATGGACTTG
TCAGGGACTAAAGTGGGGGA

Downstream 100 bases:

>100_bases
GCGTGGAAGAGCAAGCAGTGGAACTTCCCTACCCGGCACAGCTGACCGATCCCACCCGCATCCGCGCAGCGTATCTGCGC
ATGGCGAAGGTCGCGTTGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLNKTIESISRVDGLWTLPDGISTDEWAAEVRRLKEEKNALILAHNYQLPEIQDIADHTGDSLALSRIAAETDADVIVFC
GVHFMAETAKILSPEKTVLIPDANAGCSLADSLTADELREWKAEHPGAVVVSYVNTTADVKALTDICCTSSNAVDVVASL
PEDQEVLFGPDQFLGAHVRRETGRDNIHVWAGECHVHAGISGQELSQQAHDNPTADLFIHPECGCANSAIYLAGEGIVEP
ERVKMLSTGDMISQAKSTNQSTVLVATEVGMLHQLRQANPEVDFRAVNDRAACTYMKMITPAALLRCLALGEDEVTVDEE
TAAAARRSVERMIAIGNPGSGE

Sequences:

>Translated_342_residues
MLNKTIESISRVDGLWTLPDGISTDEWAAEVRRLKEEKNALILAHNYQLPEIQDIADHTGDSLALSRIAAETDADVIVFC
GVHFMAETAKILSPEKTVLIPDANAGCSLADSLTADELREWKAEHPGAVVVSYVNTTADVKALTDICCTSSNAVDVVASL
PEDQEVLFGPDQFLGAHVRRETGRDNIHVWAGECHVHAGISGQELSQQAHDNPTADLFIHPECGCANSAIYLAGEGIVEP
ERVKMLSTGDMISQAKSTNQSTVLVATEVGMLHQLRQANPEVDFRAVNDRAACTYMKMITPAALLRCLALGEDEVTVDEE
TAAAARRSVERMIAIGNPGSGE
>Mature_342_residues
MLNKTIESISRVDGLWTLPDGISTDEWAAEVRRLKEEKNALILAHNYQLPEIQDIADHTGDSLALSRIAAETDADVIVFC
GVHFMAETAKILSPEKTVLIPDANAGCSLADSLTADELREWKAEHPGAVVVSYVNTTADVKALTDICCTSSNAVDVVASL
PEDQEVLFGPDQFLGAHVRRETGRDNIHVWAGECHVHAGISGQELSQQAHDNPTADLFIHPECGCANSAIYLAGEGIVEP
ERVKMLSTGDMISQAKSTNQSTVLVATEVGMLHQLRQANPEVDFRAVNDRAACTYMKMITPAALLRCLALGEDEVTVDEE
TAAAARRSVERMIAIGNPGSGE

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=334, Percent_Identity=34.1317365269461, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36856; Mature: 36856

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKTIESISRVDGLWTLPDGISTDEWAAEVRRLKEEKNALILAHNYQLPEIQDIADHTG
CCCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCC
DSLALSRIAAETDADVIVFCGVHFMAETAKILSPEKTVLIPDANAGCSLADSLTADELRE
CHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCHHHHHH
WKAEHPGAVVVSYVNTTADVKALTDICCTSSNAVDVVASLPEDQEVLFGPDQFLGAHVRR
HHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHEECCCCCCCEEECCHHHHHHHHHH
ETGRDNIHVWAGECHVHAGISGQELSQQAHDNPTADLFIHPECGCANSAIYLAGEGIVEP
HCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCH
ERVKMLSTGDMISQAKSTNQSTVLVATEVGMLHQLRQANPEVDFRAVNDRAACTYMKMIT
HHEEEEECCHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
PAALLRCLALGEDEVTVDEETAAAARRSVERMIAIGNPGSGE
HHHHHHHHHCCCCCEEECHHHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure
MLNKTIESISRVDGLWTLPDGISTDEWAAEVRRLKEEKNALILAHNYQLPEIQDIADHTG
CCCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCC
DSLALSRIAAETDADVIVFCGVHFMAETAKILSPEKTVLIPDANAGCSLADSLTADELRE
CHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCHHHCCCHHHHHH
WKAEHPGAVVVSYVNTTADVKALTDICCTSSNAVDVVASLPEDQEVLFGPDQFLGAHVRR
HHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEHEECCCCCCCEEECCHHHHHHHHHH
ETGRDNIHVWAGECHVHAGISGQELSQQAHDNPTADLFIHPECGCANSAIYLAGEGIVEP
HCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCH
ERVKMLSTGDMISQAKSTNQSTVLVATEVGMLHQLRQANPEVDFRAVNDRAACTYMKMIT
HHEEEEECCHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHH
PAALLRCLALGEDEVTVDEETAAAARRSVERMIAIGNPGSGE
HHHHHHHHHCCCCCEEECHHHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA