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The map label for this gene is mraY

Identifier: 68535822

GI number: 68535822

Start: 892290

End: 893390

Strand: Direct

Name: mraY

Synonym: jk0747

Alternate gene names: 68535822

Gene position: 892290-893390 (Clockwise)

Preceding gene: 68535821

Following gene: 68535823

Centisome position: 36.24

GC content: 60.22

Gene sequence:

>1101_bases
ATGTTGCAAATCTTTATCGCAGGTGCGGTTGCTTTCCTTGTGTCCGTATTCCTGACCCCGGTGCTGATTCGGTGGTTCTC
CGCTGAGGGATTGGGCCAGGAGATCCGCGAGGAAGGCCCGAAGTCGCACTTTAAAAAGCGCGGCACCCCGACCATGGGCG
GGATCGCCGTTTTGGCGGGCATCGTTTTCGGCTACCTGATTGCCGTGCTGGTGGGACTAGTAACCACCGGCGCCGGGCCG
GGCGTAAGCGGCTGGTTGGTGTTGGGGCTGACCTTGGCCCTCGGCGGTCTGGGCTTTGCCGATGACTACATCAAATTGGT
CAAGGGCCGGAACCTGGGCTTGAACGCAAAGGCGAAGCTTGTAGGCCAGCTGGTTACCGCGATCGTCTTTGGCCTGCTCA
TCCTGCAGTTCCCGAACGCGCATGGTCTCACCCCGGGGTCCACACATCTGTCTTTTGTCCGTGATATTGCGACGTTCGAT
ATCGCCATCGGGCCGGCAATCGTGGGCATGATTCTGTTCCTGATCTTCATCTACCTGGTGATCTCCGCCTGGTCGAACGC
AGTGAACCTGACCGACGGGTTGGATGGCCTGGCAAGTGGCGTGACCGCGATCGTGATGGGCACCTACGTGCTGATTACCT
TCTGGCAGTTCCGTAACTCCTGCGCCGTCAGCGCACAGGCCGCATGCTATGCGGTACGTGACCCGTTGGACCTGTCGATG
CTCGCCTCCGCTGGCCTGGGTGCCTGCCTGGGCTTCCTATGGTGGAATGCAGCTCCCGCGAAGATCTTCATGGGTGATAC
TGGATCTCTGGCCCTTGGTGGCCTGGTGGCAGGTTTGTCCGTCACGACCCAGACCGAGCTGCTGATGATTCTGGTAGGCA
TCATCTTTGTCATCGAGGCTGCATCCGTGGTGATTCAGGTGGTCTCCTTCAAGGCCACCGGCAAGCGTGTCTTCCGCATG
GCGCCGATCCACCACCACTTTGAAAACAAGGGATGGGCGGAGACGACCGTCGTCATCCGCTTTTGGCTGCTCGCCGCGCT
GGCGGCGATGTCCGGCTTCGCGGTTTTCTACGCGGAGTGGCTCAACGGCGCCAGCTTCTAG

Upstream 100 bases:

>100_bases
CCGCAGGATGTAGTGCTGATCAAGGCATCGTATTCGGACGGACTATGGGCAGTGGCTGAAGGACTGCTCATCGGTGAGGA
TCAAGGAGCTTAAAAATCCC

Downstream 100 bases:

>100_bases
GCGGCTGCCGGTGGCAGACCCACAAACCCACTATTCGCTAGCAATGTAAGGACAACCCAGCCGTGGAATCGACACACGCA
CTCCAACCCGCAGAAGCCCT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLQIFIAGAVAFLVSVFLTPVLIRWFSAEGLGQEIREEGPKSHFKKRGTPTMGGIAVLAGIVFGYLIAVLVGLVTTGAGP
GVSGWLVLGLTLALGGLGFADDYIKLVKGRNLGLNAKAKLVGQLVTAIVFGLLILQFPNAHGLTPGSTHLSFVRDIATFD
IAIGPAIVGMILFLIFIYLVISAWSNAVNLTDGLDGLASGVTAIVMGTYVLITFWQFRNSCAVSAQAACYAVRDPLDLSM
LASAGLGACLGFLWWNAAPAKIFMGDTGSLALGGLVAGLSVTTQTELLMILVGIIFVIEAASVVIQVVSFKATGKRVFRM
APIHHHFENKGWAETTVVIRFWLLAALAAMSGFAVFYAEWLNGASF

Sequences:

>Translated_366_residues
MLQIFIAGAVAFLVSVFLTPVLIRWFSAEGLGQEIREEGPKSHFKKRGTPTMGGIAVLAGIVFGYLIAVLVGLVTTGAGP
GVSGWLVLGLTLALGGLGFADDYIKLVKGRNLGLNAKAKLVGQLVTAIVFGLLILQFPNAHGLTPGSTHLSFVRDIATFD
IAIGPAIVGMILFLIFIYLVISAWSNAVNLTDGLDGLASGVTAIVMGTYVLITFWQFRNSCAVSAQAACYAVRDPLDLSM
LASAGLGACLGFLWWNAAPAKIFMGDTGSLALGGLVAGLSVTTQTELLMILVGIIFVIEAASVVIQVVSFKATGKRVFRM
APIHHHFENKGWAETTVVIRFWLLAALAAMSGFAVFYAEWLNGASF
>Mature_366_residues
MLQIFIAGAVAFLVSVFLTPVLIRWFSAEGLGQEIREEGPKSHFKKRGTPTMGGIAVLAGIVFGYLIAVLVGLVTTGAGP
GVSGWLVLGLTLALGGLGFADDYIKLVKGRNLGLNAKAKLVGQLVTAIVFGLLILQFPNAHGLTPGSTHLSFVRDIATFD
IAIGPAIVGMILFLIFIYLVISAWSNAVNLTDGLDGLASGVTAIVMGTYVLITFWQFRNSCAVSAQAACYAVRDPLDLSM
LASAGLGACLGFLWWNAAPAKIFMGDTGSLALGGLVAGLSVTTQTELLMILVGIIFVIEAASVVIQVVSFKATGKRVFRM
APIHHHFENKGWAETTVVIRFWLLAALAAMSGFAVFYAEWLNGASF

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=347, Percent_Identity=40.3458213256484, Blast_Score=212, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_CORJK (Q4JW98)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250527.1
- STRING:   Q4JW98
- GeneID:   3432779
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0747
- NMPDR:   fig|306537.3.peg.1606
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- ProtClustDB:   PRK00108
- BioCyc:   CJEI306537:JK0747-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38641; Mature: 38641

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15b5cd90)-; HASH(0x15d7bb58)-; HASH(0x17c13b40)-; HASH(0x17a79468)-; HASH(0x17c13a68)-; HASH(0x17c13b58)-; HASH(0x17c57ffc)-; HASH(0x1778f094)-; HASH(0x17c57f9c)-; HASH(0x17c4b0ec)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQIFIAGAVAFLVSVFLTPVLIRWFSAEGLGQEIREEGPKSHFKKRGTPTMGGIAVLAG
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHH
IVFGYLIAVLVGLVTTGAGPGVSGWLVLGLTLALGGLGFADDYIKLVKGRNLGLNAKAKL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
VGQLVTAIVFGLLILQFPNAHGLTPGSTHLSFVRDIATFDIAIGPAIVGMILFLIFIYLV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAWSNAVNLTDGLDGLASGVTAIVMGTYVLITFWQFRNSCAVSAQAACYAVRDPLDLSM
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
LASAGLGACLGFLWWNAAPAKIFMGDTGSLALGGLVAGLSVTTQTELLMILVGIIFVIEA
HHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASVVIQVVSFKATGKRVFRMAPIHHHFENKGWAETTVVIRFWLLAALAAMSGFAVFYAEW
HHHHHHHHHHHHCCHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGASF
HCCCCH
>Mature Secondary Structure
MLQIFIAGAVAFLVSVFLTPVLIRWFSAEGLGQEIREEGPKSHFKKRGTPTMGGIAVLAG
CEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHH
IVFGYLIAVLVGLVTTGAGPGVSGWLVLGLTLALGGLGFADDYIKLVKGRNLGLNAKAKL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHH
VGQLVTAIVFGLLILQFPNAHGLTPGSTHLSFVRDIATFDIAIGPAIVGMILFLIFIYLV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAWSNAVNLTDGLDGLASGVTAIVMGTYVLITFWQFRNSCAVSAQAACYAVRDPLDLSM
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
LASAGLGACLGFLWWNAAPAKIFMGDTGSLALGGLVAGLSVTTQTELLMILVGIIFVIEA
HHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASVVIQVVSFKATGKRVFRMAPIHHHFENKGWAETTVVIRFWLLAALAAMSGFAVFYAEW
HHHHHHHHHHHHCCHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNGASF
HCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA