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The map label for this gene is yfdZ [C]

Identifier: 66766995

GI number: 66766995

Start: 791725

End: 792909

Strand: Reverse

Name: yfdZ [C]

Synonym: XC_0658

Alternate gene names: 66766995

Gene position: 792909-791725 (Counterclockwise)

Preceding gene: 66767002

Following gene: 77761102

Centisome position: 15.4

GC content: 66.33

Gene sequence:

>1185_bases
ATGGACTCACTGCTTTCGCCCGTGTCCGGCTATAGCCGCCGCAGCCAGGACATCGCGCCCTTCCATGTGATGGCCCTGCT
GGCCCGCGCCAACGCACTGGAACAGGCCGGCCACGATGTCATCCACCTGGAAATCGGCGAGCCGGACTTCACCACCGCTG
CGCCCGTGGTGGCCGCCGGCCAGGCTGCATTGGCCGCAGGCCACACCCGTTACACCGCCGCCCGCGGGCTGCCCGCGTTG
CGCGAGGCAATTGCCGGGTTTTACGCGCAGCGTTACGGCTGCCACATCGATCCCGAGCGCGTGCTGGTCACCCCGGGAGG
CTCCGGCGCTTTGCTGCTGGCCAGCAGCCTGTTGGTCGACCCGAGCAAGCATTGGTTGCTCGCCGACCCGGGGTATCCGT
GCAACCGTCACTTCCTGCGCCTGGTCGAAGCTGGCGCGCAGCTGGTACCGGTGGGCCCGGACAGCGACTACCAACTGACC
CCGGCGCTGGTGGATGCCTGCTGGACGGCCGACAGCGTTGGCGCGTTGGTGGCCTCACCGGCCAACCCCACCGGCAGCGT
GCTCTCGCGTGCGCAGTTGGCCGCCTTGTCGCAGGCCTTGCAGGCGCGTGGTGGCCACCTGGTGGTGGATGAGATCTACC
ACGGCCTGACCTACGGCCTGGACGCGCACAGCGTGCTGGAAGTGGATGACAGCGCATTCGTGCTGAACAGTTTTTCCAAA
TACTTCGGCATGACCGGCTGGCGCCTGGGCTGGCTGATCGCCCCACCCTCTGCGGTGCCCGAGTTGGAAAAACTCGCGCA
GAACCTCTACATCAGCGCCTCGTCCATCGCCCAGCATGCGGCCCTGGCCTGCTTCACGCCCGAGAGCATCGCCATCTTCG
AAGCGCGCCGCGCCGAGTTCCAGCAACGCCGCGATTACCTGTTGCCTGCACTGCGCGCACTGGGCTTCGACATCGCCGTC
GAGCCACAAGGCGCGTTCTATCTGTATGCCGACATCAGCGCATTCTCCAAGGACGCGCAGGCCTTCTGTACGCACTTCCT
GGAAACCGAGCATGTTGCCTTCACTCCCGGCATCGACTTCGGCTTCCACCGCGCCAACCAGCACGTCCGCATCGCCTATA
CGCAGAGCCTGCCGCGCCTTGAGCAGGCGGTGGAGCGCATTGCGCGTGGGTTACGGCACATCTGA

Upstream 100 bases:

>100_bases
GTCCGTTGGATGAACGCAATGCCATCCCAGCGCGCGAGTGTGGAAGAGGCCGCCGGGGAGCGTCATGTGTCCGAGGTCAT
GCTGGTCTATCATCTTCGCA

Downstream 100 bases:

>100_bases
ACGGAGATACGAGACGGGCTAACGCCACCCCGCTGACAGTGCAGTCTGCGTGCCTACTTGACTGGCCTACTCTGGCCCGC
GTCATTGTGTGCCGTAGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDSLLSPVSGYSRRSQDIAPFHVMALLARANALEQAGHDVIHLEIGEPDFTTAAPVVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYGCHIDPERVLVTPGGSGALLLASSLLVDPSKHWLLADPGYPCNRHFLRLVEAGAQLVPVGPDSDYQLT
PALVDACWTADSVGALVASPANPTGSVLSRAQLAALSQALQARGGHLVVDEIYHGLTYGLDAHSVLEVDDSAFVLNSFSK
YFGMTGWRLGWLIAPPSAVPELEKLAQNLYISASSIAQHAALACFTPESIAIFEARRAEFQQRRDYLLPALRALGFDIAV
EPQGAFYLYADISAFSKDAQAFCTHFLETEHVAFTPGIDFGFHRANQHVRIAYTQSLPRLEQAVERIARGLRHI

Sequences:

>Translated_394_residues
MDSLLSPVSGYSRRSQDIAPFHVMALLARANALEQAGHDVIHLEIGEPDFTTAAPVVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYGCHIDPERVLVTPGGSGALLLASSLLVDPSKHWLLADPGYPCNRHFLRLVEAGAQLVPVGPDSDYQLT
PALVDACWTADSVGALVASPANPTGSVLSRAQLAALSQALQARGGHLVVDEIYHGLTYGLDAHSVLEVDDSAFVLNSFSK
YFGMTGWRLGWLIAPPSAVPELEKLAQNLYISASSIAQHAALACFTPESIAIFEARRAEFQQRRDYLLPALRALGFDIAV
EPQGAFYLYADISAFSKDAQAFCTHFLETEHVAFTPGIDFGFHRANQHVRIAYTQSLPRLEQAVERIARGLRHI
>Mature_394_residues
MDSLLSPVSGYSRRSQDIAPFHVMALLARANALEQAGHDVIHLEIGEPDFTTAAPVVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYGCHIDPERVLVTPGGSGALLLASSLLVDPSKHWLLADPGYPCNRHFLRLVEAGAQLVPVGPDSDYQLT
PALVDACWTADSVGALVASPANPTGSVLSRAQLAALSQALQARGGHLVVDEIYHGLTYGLDAHSVLEVDDSAFVLNSFSK
YFGMTGWRLGWLIAPPSAVPELEKLAQNLYISASSIAQHAALACFTPESIAIFEARRAEFQQRRDYLLPALRALGFDIAV
EPQGAFYLYADISAFSKDAQAFCTHFLETEHVAFTPGIDFGFHRANQHVRIAYTQSLPRLEQAVERIARGLRHI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=326, Percent_Identity=28.8343558282209, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881279, Length=326, Percent_Identity=28.8343558282209, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI56713256, Length=322, Percent_Identity=25.1552795031056, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI56713254, Length=322, Percent_Identity=25.1552795031056, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI169881281, Length=213, Percent_Identity=25.8215962441315, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=22.8855721393035, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI149944424, Length=206, Percent_Identity=29.6116504854369, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=27.4358974358974, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786816, Length=350, Percent_Identity=28.2857142857143, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=26.6839378238342, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=24.2744063324538, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=24.2744063324538, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=25.1989389920424, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=21.5938303341902, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=285, Percent_Identity=24.2105263157895, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646114, Length=285, Percent_Identity=24.2105263157895, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573067, Length=285, Percent_Identity=24.2105263157895, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573065, Length=285, Percent_Identity=24.2105263157895, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=23.989218328841, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42505; Mature: 42505

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLLSPVSGYSRRSQDIAPFHVMALLARANALEQAGHDVIHLEIGEPDFTTAAPVVAAG
CCCHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYGCHIDPERVLVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
PSKHWLLADPGYPCNRHFLRLVEAGAQLVPVGPDSDYQLTPALVDACWTADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEECHHHHHHHHCCCCCCCEEECC
ANPTGSVLSRAQLAALSQALQARGGHLVVDEIYHGLTYGLDAHSVLEVDDSAFVLNSFSK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPSAVPELEKLAQNLYISASSIAQHAALACFTPESIAIFEARRAEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHEEEEECCCCHHHHHHHHHHH
QQRRDYLLPALRALGFDIAVEPQGAFYLYADISAFSKDAQAFCTHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCC
GFHRANQHVRIAYTQSLPRLEQAVERIARGLRHI
CHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSLLSPVSGYSRRSQDIAPFHVMALLARANALEQAGHDVIHLEIGEPDFTTAAPVVAAG
CCCHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYGCHIDPERVLVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
PSKHWLLADPGYPCNRHFLRLVEAGAQLVPVGPDSDYQLTPALVDACWTADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEECHHHHHHHHCCCCCCCEEECC
ANPTGSVLSRAQLAALSQALQARGGHLVVDEIYHGLTYGLDAHSVLEVDDSAFVLNSFSK
CCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPSAVPELEKLAQNLYISASSIAQHAALACFTPESIAIFEARRAEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHEEEEECCCCHHHHHHHHHHH
QQRRDYLLPALRALGFDIAVEPQGAFYLYADISAFSKDAQAFCTHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCC
GFHRANQHVRIAYTQSLPRLEQAVERIARGLRHI
CHHCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]