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The map label for this gene is cat1 [H]

Identifier: 66766889

GI number: 66766889

Start: 656446

End: 657960

Strand: Reverse

Name: cat1 [H]

Synonym: XC_0550

Alternate gene names: 66766889

Gene position: 657960-656446 (Counterclockwise)

Preceding gene: 66766892

Following gene: 66766888

Centisome position: 12.78

GC content: 64.75

Gene sequence:

>1515_bases
ATGTCCGACGAACGCATCCTCAACGCGCCGCTGCGCGACCACCTGGTCTCTGCCGAGGCCGCTGCTGCGCTGATCCAGCC
CGGCGAGACCGTGGCGATGAGCGGCTTCACCGGGTCGGGTTATCCCAAGGCAGTGCCGATGGCGCTGGCGCAGCGCATCG
AAGCGGCGCACCTGCAGGGCGAAGCGTTCCAGATCAAGCTGATGACCGGCGCCTCCACCGCGCCCGAGCTCGATGGCGCG
CTGGCCAAGGCCGACGGCATCGCCATGCGCATGCCGTTCCAGTCCGACCCGGATGCGCGCCAACGCATCAATGCCGGCAC
GCTGGACTACATCGATATCCATCTGAGCCACGTTGCCCAGCACGTGTGGTTCGGCTTCTACGGGCAGATCGACACCGCGG
TGGTGGAAGTGTCGGCGATCCGCGCCGATGGCAGCCTGGTGCCGTCCACCTCCATCGGTAACAACAAGACCTGGCTGGAC
CTGGCCAGGAAAGTGATCATCGAGGTCAACGACTGGCAACCGGCCGGCCTGGATGGCATGCACGATGTGTATTACGGCAC
CGCGCTGCCACCGCACCGCAAACCGATTCCGCTGCTGCACGGCGACGACCGCATCGGCGAGCCCAGCCTGCGCTGCGACC
CGGACAAGATCGTGGCCGTGGTGCGTACGCATGGCCCGGACCGCAACAGCCCGTTTGCCGCTGCCGATGACAGCAGCGAG
CGCATCGCCGAACACCTGATCGCCTTCCTGCGACACGAGGTGAGCAAGGGCCGGCTGCCGGCGAACCTGCTGCCGCTGCA
ATCGGGCGTGGGCAATATTCCCAATGCGGTGCTGGCCGGCCTGGCACGTAGCGGTTTCCGCGACCTGGAAGCCTTCACCG
AAGTGATCCAGGACGGCATGCTGGCGCTGCTGCGCGATGGCGTCTTGCGTTATGCCTCGTGCACCGGTTTTGCGCTCAGC
CCGGAAGGCAACGAAGAATTCAAGCGCAACATCGATTTCTACCGGCAGCGCATCGTGATGCGCACGCAGGAGATCTCCAA
CCATCCCGAGCTGGTGCGGCGGCTGGGCTGCATCGGCATGAACGGCATGATCGAGGCCGACCTGTACGGCAACGTCAATT
CCACCCATGTCATGGGCAGCCGCATCATGAACGGCATCGGCGGCTCCGGCGATTTCGCGCGCAACGGGTTCCTGTCGATC
TTCCTCAGCCCCAGCATCGCCAAGGCCGGCAGTATTTCCTCAATCGTGCCGATGGTCAGCCATGTCGACCACACCGAACA
CGACGTCTCAGTGATCGTGACCGAACAAGGCCTGGCCGACCTGCGCGGCCTGACGCCCAAGCAACGTGCACGCCAGCTGC
TAGAGCACTGCGTGCATCCGCGTTACCGCGACGCGCTGGAAGACTACGTGGCACGTGCCAATCGCGACAGCTATGGCAAG
CACACGCCGCATCTGCTGACCGAAGCATTGGCGTGGCACCAGCGGTGGCTGGAGACTGGAGATATGTTGGGGTGA

Upstream 100 bases:

>100_bases
CCCGCCGCCTGACCGCATACACCATTGCACCATCGTCGAAGCCCCGCCCAGGCAACGCAGCGGCGATAATTTGGCTTCCC
CCGTCACACGCTATGCCCCC

Downstream 100 bases:

>100_bases
GTTGGGGATTCGGGATTCGGGATTCGTCAGTTTCAGCCGCTCTTTGCAGCGCGATCAATGTGTTGCACGAACTTCAACTT
GGGCCGGTGCTTTGCCGTAG

Product: CoA tranferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSDERILNAPLRDHLVSAEAAAALIQPGETVAMSGFTGSGYPKAVPMALAQRIEAAHLQGEAFQIKLMTGASTAPELDGA
LAKADGIAMRMPFQSDPDARQRINAGTLDYIDIHLSHVAQHVWFGFYGQIDTAVVEVSAIRADGSLVPSTSIGNNKTWLD
LARKVIIEVNDWQPAGLDGMHDVYYGTALPPHRKPIPLLHGDDRIGEPSLRCDPDKIVAVVRTHGPDRNSPFAAADDSSE
RIAEHLIAFLRHEVSKGRLPANLLPLQSGVGNIPNAVLAGLARSGFRDLEAFTEVIQDGMLALLRDGVLRYASCTGFALS
PEGNEEFKRNIDFYRQRIVMRTQEISNHPELVRRLGCIGMNGMIEADLYGNVNSTHVMGSRIMNGIGGSGDFARNGFLSI
FLSPSIAKAGSISSIVPMVSHVDHTEHDVSVIVTEQGLADLRGLTPKQRARQLLEHCVHPRYRDALEDYVARANRDSYGK
HTPHLLTEALAWHQRWLETGDMLG

Sequences:

>Translated_504_residues
MSDERILNAPLRDHLVSAEAAAALIQPGETVAMSGFTGSGYPKAVPMALAQRIEAAHLQGEAFQIKLMTGASTAPELDGA
LAKADGIAMRMPFQSDPDARQRINAGTLDYIDIHLSHVAQHVWFGFYGQIDTAVVEVSAIRADGSLVPSTSIGNNKTWLD
LARKVIIEVNDWQPAGLDGMHDVYYGTALPPHRKPIPLLHGDDRIGEPSLRCDPDKIVAVVRTHGPDRNSPFAAADDSSE
RIAEHLIAFLRHEVSKGRLPANLLPLQSGVGNIPNAVLAGLARSGFRDLEAFTEVIQDGMLALLRDGVLRYASCTGFALS
PEGNEEFKRNIDFYRQRIVMRTQEISNHPELVRRLGCIGMNGMIEADLYGNVNSTHVMGSRIMNGIGGSGDFARNGFLSI
FLSPSIAKAGSISSIVPMVSHVDHTEHDVSVIVTEQGLADLRGLTPKQRARQLLEHCVHPRYRDALEDYVARANRDSYGK
HTPHLLTEALAWHQRWLETGDMLG
>Mature_503_residues
SDERILNAPLRDHLVSAEAAAALIQPGETVAMSGFTGSGYPKAVPMALAQRIEAAHLQGEAFQIKLMTGASTAPELDGAL
AKADGIAMRMPFQSDPDARQRINAGTLDYIDIHLSHVAQHVWFGFYGQIDTAVVEVSAIRADGSLVPSTSIGNNKTWLDL
ARKVIIEVNDWQPAGLDGMHDVYYGTALPPHRKPIPLLHGDDRIGEPSLRCDPDKIVAVVRTHGPDRNSPFAAADDSSER
IAEHLIAFLRHEVSKGRLPANLLPLQSGVGNIPNAVLAGLARSGFRDLEAFTEVIQDGMLALLRDGVLRYASCTGFALSP
EGNEEFKRNIDFYRQRIVMRTQEISNHPELVRRLGCIGMNGMIEADLYGNVNSTHVMGSRIMNGIGGSGDFARNGFLSIF
LSPSIAKAGSISSIVPMVSHVDHTEHDVSVIVTEQGLADLRGLTPKQRARQLLEHCVHPRYRDALEDYVARANRDSYGKH
TPHLLTEALAWHQRWLETGDMLG

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=490, Percent_Identity=45.5102040816327, Blast_Score=440, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17538151, Length=474, Percent_Identity=25.7383966244726, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32563853, Length=223, Percent_Identity=30.9417040358744, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=515, Percent_Identity=43.495145631068, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI21358615, Length=484, Percent_Identity=24.1735537190083, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55009; Mature: 54878

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDERILNAPLRDHLVSAEAAAALIQPGETVAMSGFTGSGYPKAVPMALAQRIEAAHLQG
CCCCCEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
EAFQIKLMTGASTAPELDGALAKADGIAMRMPFQSDPDARQRINAGTLDYIDIHLSHVAQ
CEEEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
HVWFGFYGQIDTAVVEVSAIRADGSLVPSTSIGNNKTWLDLARKVIIEVNDWQPAGLDGM
HHHHHHHCCHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCC
HDVYYGTALPPHRKPIPLLHGDDRIGEPSLRCDPDKIVAVVRTHGPDRNSPFAAADDSSE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHH
RIAEHLIAFLRHEVSKGRLPANLLPLQSGVGNIPNAVLAGLARSGFRDLEAFTEVIQDGM
HHHHHHHHHHHHHHHCCCCCCHHCCHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LALLRDGVLRYASCTGFALSPEGNEEFKRNIDFYRQRIVMRTQEISNHPELVRRLGCIGM
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
NGMIEADLYGNVNSTHVMGSRIMNGIGGSGDFARNGFLSIFLSPSIAKAGSISSIVPMVS
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHCCCCHHHHHHHHH
HVDHTEHDVSVIVTEQGLADLRGLTPKQRARQLLEHCVHPRYRDALEDYVARANRDSYGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
HTPHLLTEALAWHQRWLETGDMLG
CCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDERILNAPLRDHLVSAEAAAALIQPGETVAMSGFTGSGYPKAVPMALAQRIEAAHLQG
CCCCEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
EAFQIKLMTGASTAPELDGALAKADGIAMRMPFQSDPDARQRINAGTLDYIDIHLSHVAQ
CEEEEEEEECCCCCCCCCCHHHHCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
HVWFGFYGQIDTAVVEVSAIRADGSLVPSTSIGNNKTWLDLARKVIIEVNDWQPAGLDGM
HHHHHHHCCHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCC
HDVYYGTALPPHRKPIPLLHGDDRIGEPSLRCDPDKIVAVVRTHGPDRNSPFAAADDSSE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHH
RIAEHLIAFLRHEVSKGRLPANLLPLQSGVGNIPNAVLAGLARSGFRDLEAFTEVIQDGM
HHHHHHHHHHHHHHHCCCCCCHHCCHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LALLRDGVLRYASCTGFALSPEGNEEFKRNIDFYRQRIVMRTQEISNHPELVRRLGCIGM
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
NGMIEADLYGNVNSTHVMGSRIMNGIGGSGDFARNGFLSIFLSPSIAKAGSISSIVPMVS
CCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHCCCCHHHHHHHHH
HVDHTEHDVSVIVTEQGLADLRGLTPKQRARQLLEHCVHPRYRDALEDYVARANRDSYGK
HCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
HTPHLLTEALAWHQRWLETGDMLG
CCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]