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The map label for this gene is fabG [H]

Identifier: 66766739

GI number: 66766739

Start: 458359

End: 459156

Strand: Reverse

Name: fabG [H]

Synonym: XC_0396

Alternate gene names: 66766739

Gene position: 459156-458359 (Counterclockwise)

Preceding gene: 66766740

Following gene: 66766738

Centisome position: 8.92

GC content: 70.68

Gene sequence:

>798_bases
TTGAAGGAGCACCGCATGGATCTGGGAATCGCCGGGCGCTGGGCCTTGGTATGTGCCGCCAGCAAGGGCCTGGGACTGGG
CTGCGCACAGGCGCTGGCACGCGAAGGCGCCAATGTCGTGATTGTCGCGCGTGGCCGCGAGGCTTTGGAGCAGTCCGCCA
GCAACTTGCGCGCCCTGCCCGGCGCGGGTGAGGTACGCAGCGTCGTCGCCGACATCACCACCAGCGAAGGCCGTGCCGCT
GCGCTGGCCGCCTGCCCGCAGGTCGACATCCTGATCAACAACGCCGGCGGGCCGCCGCCGGGCGATTTCCGTCAGTGGGA
GCGCGCGGACTGGCTGCGTGCGCTCGACGCCAACATGCTGGCCCCGATCGAACTGATCCGCGCCACGGTCGATGCGATGC
GCGCGCGGCGCTTCGGCCGCATCGTCAACATCACCTCCAGCGCGGTGAAGGCGCCGATCGACATCCTGGGCCTGTCCAAC
GGCGCGCGCGCCGGTCTCACCGGCTTCGTGGCCGGGCTGGCGCGCAGCACCGTGGCCGACAACGTCACCCTCAACAACCT
GTTGCCGGGCCAGTTCGCCACCGACCGGCTGCGCGGCAACTTCGCCGCGATCGCCGAGCAACAAGGCACCAGCGCCGAGG
CGGTGGCCGCGCACAAACGCGCCGGCATCCCGGCCGGGCGCTTTGGCGAGCCGGACGAGTTCGGCGCGGCCTGCGCATTC
CTGTGCAGTGCCCAGGCCGGCTACATCACCGGACAGAACCTGCTGATCGACGGCGGCGCCTACCCGGGCACGTTTTGA

Upstream 100 bases:

>100_bases
CAATGCGAGATCACTCCTGGGACCACCGCCAATCAACACACTGTCCGATCCACCACCACACGCCGTGCAGCCGCGATCAC
CGATCATGCGCATTCGTTGA

Downstream 100 bases:

>100_bases
CGCCACTGGCGCTGCGCATCAACACGCCGCCGCGCATCACACCGTGTCGCTGCGGCAATTCCCTCGGCGGCGTGCAGCGG
CGACAATAGCGCGGCAATGA

Product: oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKEHRMDLGIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALPGAGEVRSVVADITTSEGRAA
ALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDAMRARRFGRIVNITSSAVKAPIDILGLSN
GARAGLTGFVAGLARSTVADNVTLNNLLPGQFATDRLRGNFAAIAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAF
LCSAQAGYITGQNLLIDGGAYPGTF

Sequences:

>Translated_265_residues
MKEHRMDLGIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALPGAGEVRSVVADITTSEGRAA
ALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDAMRARRFGRIVNITSSAVKAPIDILGLSN
GARAGLTGFVAGLARSTVADNVTLNNLLPGQFATDRLRGNFAAIAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAF
LCSAQAGYITGQNLLIDGGAYPGTF
>Mature_265_residues
MKEHRMDLGIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALPGAGEVRSVVADITTSEGRAA
ALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDAMRARRFGRIVNITSSAVKAPIDILGLSN
GARAGLTGFVAGLARSTVADNVTLNNLLPGQFATDRLRGNFAAIAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAF
LCSAQAGYITGQNLLIDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=29.296875, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=28.2352941176471, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=26.8482490272374, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=25.974025974026, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=258, Percent_Identity=26.7441860465116, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=27.6264591439689, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226371731, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=32.6923076923077, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082160, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=31.4176245210728, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=24.4186046511628, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=26.4591439688716, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=26.6932270916335, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=263, Percent_Identity=30.0380228136882, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.7984790874525, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.7992277992278, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=30.9433962264151, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=31.1111111111111, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=28.735632183908, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.0769230769231, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.8625954198473, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=27.5193798449612, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=27.7372262773723, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.6259541984733, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.9850746268657, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.2357414448669, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=25.7246376811594, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=28, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=25.5905511811024, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=26.2745098039216, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=29.8449612403101, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=30.6201550387597, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.0155642023346, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639444, Length=266, Percent_Identity=26.6917293233083, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24584752, Length=157, Percent_Identity=34.3949044585987, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27419; Mature: 27419

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEHRMDLGIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALP
CCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCC
GAGEVRSVVADITTSEGRAAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANML
CCHHHHHHHHHHCCCCCCEEEHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHH
APIELIRATVDAMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVAD
HHHHHHHHHHHHHHHHHHHHEEEECHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHC
NVTLNNLLPGQFATDRLRGNFAAIAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAF
CCEECCCCCCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LCSAQAGYITGQNLLIDGGAYPGTF
HHHCCCCEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MKEHRMDLGIAGRWALVCAASKGLGLGCAQALAREGANVVIVARGREALEQSASNLRALP
CCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCC
GAGEVRSVVADITTSEGRAAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANML
CCHHHHHHHHHHCCCCCCEEEHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHH
APIELIRATVDAMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVAD
HHHHHHHHHHHHHHHHHHHHEEEECHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHC
NVTLNNLLPGQFATDRLRGNFAAIAEQQGTSAEAVAAHKRAGIPAGRFGEPDEFGAACAF
CCEECCCCCCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
LCSAQAGYITGQNLLIDGGAYPGTF
HHHCCCCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]