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The map label for this gene is nccB [H]

Identifier: 66045857

GI number: 66045857

Start: 3178778

End: 3179881

Strand: Direct

Name: nccB [H]

Synonym: Psyr_2621

Alternate gene names: 66045857

Gene position: 3178778-3179881 (Clockwise)

Preceding gene: 66045856

Following gene: 66045858

Centisome position: 52.17

GC content: 65.67

Gene sequence:

>1104_bases
ATGAGGAAGATACACGTTTATGGGCTGCTGACGCTGGCGGTGTTGGGCGTTTCGGGCTGGCTATTGTCTGGCCGCGCAGA
GCCGCCCCCGGCCGCTGCGGCGCCGCCGGCCACCAGCCTGACGGTAGAGGCAGTGCAACCGCGCCGCGAAGACTGGCCGC
AGGAACGGGTGGCCAGTGGTGCGCTTGCGCCGTGGCAGGAAGCCGTGATCAGTGCAGAGACCGGAAGCTTGCGTATCGCC
AGCCTGAAGGCTGATATCGGCGATCAGGTGAAGAAGGGCCAGGTTTTGGCGACCCTGGCCGATGACAGCGTGCTGGCTGA
GGAAAACAAGCAGAAGTCGGCGGCCGCCCAGGCCACTGCGCAACTGCAGGAAGCCCGCTCCAATGCCAGGCGGGCGGCCT
CGGTAGGTCAGAGCGGCGCCCTGTCCGAGCAGAAACTGGAAGAGTACCGGGTCAAGGTGCAGACCGCCGAAGCTGACCTG
GCCTCGGCGAATGCCGATCTGCGCAGCATCCGGATCAAGCTTGCGCAGACGCGCATCGTCGCGGTGGATGACGGGATTAT
CTCCGGGCGCAAGGCCTTGCTTGGCGATGTGGTATCGGCGGGCAGTGAAATGTTCAGGATGATCCGCGATGGCCGCATCG
AGTGGCAGGCGGAACTGGATGCCCAGCAACTGCCAGGCGTCAAGGCCGGTCAGCTCGCCCGTGTGACGCTGCCCGGTGGT
ATTGCGGTGCAAGGGCGCGTGCGGCTGGTCTCGCCAATGCTCGACAGCAAGACCAGCAGGGCGCTGGTCTATGTCTCCCT
GCCGGTGGGGTCTGTGGCGCGCGCCGGCATGTACGCCAGCGGTCGCATCGAACTGCCGTCCAGCCCGGCGCTGACGGTTC
CGGACACCAGCGTGATCCTGCGCGACGGGCGCTCTTATGTGTTTGTGCTGGGCAAGGACATGCGCGTCAGCCAACAGGTG
GTCGAGGTCGGAAGACGTCGTGGATCGGCGCTGGAAATCCTCGGCGGCCTGCCAGAGCAGGCACAGATCGTCCGTAGCGG
TGGGGCCTTTCTCAATGACGGGGCCAGCGTGACACTGGTCAACGCCGAGGCCCGTGTGCAATGA

Upstream 100 bases:

>100_bases
ATCAGGTTCGCTACTGGATTGCCCTGTACAAGGCCCTGGGCGGTGGATGGCAGGACAGTCGCGAAGGTTTGGCCGGTGAA
ACACCGAAGCGGGGCGGCGT

Downstream 100 bases:

>100_bases
ATATCTCCGCGCTGTCGATTCGTTACCCGGTCCCGGCGGTCATGCTGTTTTTACTGCTGACCCTGTTTGGTTTCCTCGGG
TTCGAGCGCCTCGGTATTCA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRKIHVYGLLTLAVLGVSGWLLSGRAEPPPAAAAPPATSLTVEAVQPRREDWPQERVASGALAPWQEAVISAETGSLRIA
SLKADIGDQVKKGQVLATLADDSVLAEENKQKSAAAQATAQLQEARSNARRAASVGQSGALSEQKLEEYRVKVQTAEADL
ASANADLRSIRIKLAQTRIVAVDDGIISGRKALLGDVVSAGSEMFRMIRDGRIEWQAELDAQQLPGVKAGQLARVTLPGG
IAVQGRVRLVSPMLDSKTSRALVYVSLPVGSVARAGMYASGRIELPSSPALTVPDTSVILRDGRSYVFVLGKDMRVSQQV
VEVGRRRGSALEILGGLPEQAQIVRSGGAFLNDGASVTLVNAEARVQ

Sequences:

>Translated_367_residues
MRKIHVYGLLTLAVLGVSGWLLSGRAEPPPAAAAPPATSLTVEAVQPRREDWPQERVASGALAPWQEAVISAETGSLRIA
SLKADIGDQVKKGQVLATLADDSVLAEENKQKSAAAQATAQLQEARSNARRAASVGQSGALSEQKLEEYRVKVQTAEADL
ASANADLRSIRIKLAQTRIVAVDDGIISGRKALLGDVVSAGSEMFRMIRDGRIEWQAELDAQQLPGVKAGQLARVTLPGG
IAVQGRVRLVSPMLDSKTSRALVYVSLPVGSVARAGMYASGRIELPSSPALTVPDTSVILRDGRSYVFVLGKDMRVSQQV
VEVGRRRGSALEILGGLPEQAQIVRSGGAFLNDGASVTLVNAEARVQ
>Mature_367_residues
MRKIHVYGLLTLAVLGVSGWLLSGRAEPPPAAAAPPATSLTVEAVQPRREDWPQERVASGALAPWQEAVISAETGSLRIA
SLKADIGDQVKKGQVLATLADDSVLAEENKQKSAAAQATAQLQEARSNARRAASVGQSGALSEQKLEEYRVKVQTAEADL
ASANADLRSIRIKLAQTRIVAVDDGIISGRKALLGDVVSAGSEMFRMIRDGRIEWQAELDAQQLPGVKAGQLARVTLPGG
IAVQGRVRLVSPMLDSKTSRALVYVSLPVGSVARAGMYASGRIELPSSPALTVPDTSVILRDGRSYVFVLGKDMRVSQQV
VEVGRRRGSALEILGGLPEQAQIVRSGGAFLNDGASVTLVNAEARVQ

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38764; Mature: 38764

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIHVYGLLTLAVLGVSGWLLSGRAEPPPAAAAPPATSLTVEAVQPRREDWPQERVASG
CCEEEHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHCCCHHHHHCC
ALAPWQEAVISAETGSLRIASLKADIGDQVKKGQVLATLADDSVLAEENKQKSAAAQATA
CCCCHHHHHEECCCCCEEEEEECCCCCCHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHH
QLQEARSNARRAASVGQSGALSEQKLEEYRVKVQTAEADLASANADLRSIRIKLAQTRIV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCHHHHCCCCHHHEEEEEEEEEEE
AVDDGIISGRKALLGDVVSAGSEMFRMIRDGRIEWQAELDAQQLPGVKAGQLARVTLPGG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCEEEEECCCC
IAVQGRVRLVSPMLDSKTSRALVYVSLPVGSVARAGMYASGRIELPSSPALTVPDTSVIL
EEEECEEEEECHHHCCCCCCEEEEEECCCCHHHHCCCCCCCEEECCCCCCEECCCCEEEE
RDGRSYVFVLGKDMRVSQQVVEVGRRRGSALEILGGLPEQAQIVRSGGAFLNDGASVTLV
ECCCEEEEEECCCCHHHHHHHHHHHHCCCEEHHHCCCCHHHHHHHCCCCEEECCCEEEEE
NAEARVQ
ECCEECC
>Mature Secondary Structure
MRKIHVYGLLTLAVLGVSGWLLSGRAEPPPAAAAPPATSLTVEAVQPRREDWPQERVASG
CCEEEHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEEEECCCCHHCCCHHHHHCC
ALAPWQEAVISAETGSLRIASLKADIGDQVKKGQVLATLADDSVLAEENKQKSAAAQATA
CCCCHHHHHEECCCCCEEEEEECCCCCCHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHH
QLQEARSNARRAASVGQSGALSEQKLEEYRVKVQTAEADLASANADLRSIRIKLAQTRIV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEEECCCHHHHCCCCHHHEEEEEEEEEEE
AVDDGIISGRKALLGDVVSAGSEMFRMIRDGRIEWQAELDAQQLPGVKAGQLARVTLPGG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCEEEEECCCC
IAVQGRVRLVSPMLDSKTSRALVYVSLPVGSVARAGMYASGRIELPSSPALTVPDTSVIL
EEEECEEEEECHHHCCCCCCEEEEEECCCCHHHHCCCCCCCEEECCCCCCEECCCCEEEE
RDGRSYVFVLGKDMRVSQQVVEVGRRRGSALEILGGLPEQAQIVRSGGAFLNDGASVTLV
ECCCEEEEEECCCCHHHHHHHHHHHHCCCEEHHHCCCCHHHHHHHCCCCEEECCCEEEEE
NAEARVQ
ECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]