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The map label for this gene is yaaU [H]

Identifier: 66045546

GI number: 66045546

Start: 2681686

End: 2683137

Strand: Direct

Name: yaaU [H]

Synonym: Psyr_2306

Alternate gene names: 66045546

Gene position: 2681686-2683137 (Clockwise)

Preceding gene: 66045545

Following gene: 66045552

Centisome position: 44.01

GC content: 62.26

Gene sequence:

>1452_bases
ATGAGCACATCGAGCGACAAAGGCACCGTCTTCGAAACCGATTTGCCCGCGCGTCTGGACCGCCTGCCCTGGGGACGGTT
CCACACCTTGCTGGTGGTTGCGCTGGGGATCACCTGGCTGCTGGACGGTCTGGAAGTCACCCTCGCAGGCTCCGTCGCCG
GGGCCTTGAAAGCCAGCCCGGCGCTCAATCTCAGCAACAGCGACATTGGCCTGGCGGGTGCCGCCTATATTGCCGGTGCC
GTGCTGGGCGCGTTGTTCTTTGGCTGGCTGGCGGACCGTCTCGGGCGTCGCAAGCTGTTCTTCATCACCTTGCTGCTGTA
TGTCGGCGCAACGGCCGCCACGGCGTTTTCTTTCAGTATGTGGAGCTTCATGCTGTTCCGCTTCCTGACCGGCATGGGCA
TCGGCGGCGAATACACGGCAATCAATTCGACCATTCAGGAATTTACCCCGGCCCGCTACCGTGGGTGGGTCGACCTGACT
ATCAATGGCACGTTCTGGCTGGGCGCCGCGCTCGGTGCGATTGGCTCGATTGTCTTGCTCGACCCGCTGTGGGTTGGCGC
CGAGCTGGGCTGGCGCCTGTGTTTCGGGATTGGTGCGGTATTGGGCCTGCTGGTTCTGCTGATGCGACTGTGGCTGCCAG
AGAGCCCGCGCTGGCTGTTGATACACGGCCAGGCTGAACAGGCCAGGCAGATCGTCGAGCAGATAGAAGCAGGCTTGCAG
CGTCAGGGCCACGTACTGCCCGCAGTGTCGGGAAAACCCCTGCGCCTGCATGCCCGTGACCACACGCCGCTGGGCGAGGT
CGCCAGAACGTTACTGGTGACGTTTCGACAGCGTTCGCTGGTAGGCCTGACGCTGCTAACGGCCCAGGCGTTTTTCTACA
ATGCGATTTTTTTCACTTACGCACTGGTGCTGACCGACTTCTATGATGTGCCGGCCGAGCGCGTCGGCTGGTACGTGCTG
CCACTGGCGCTGGGCAATTTCTGCGGTCCGCTGCTGCTGGGCAGACTGTTTGACGTGGTCGGTCGACGGGTGATGATCAG
CCTCACCTATGGCGTGTCGGGCGTGCTGCTGGCGATCAGCGGCTACCTGTTCCAGCAAGGCGTGCTGGACGTCACCCAGC
AGGCCATCGCCTGGATGGTGATTTTCTTCTTTGCATCGGCAGCGGCCAGCTCGGCCTACCTGACCGTCGCCGAAACCTTT
CCACTGGAAATTCGTGCCCTGGCGATTGCGGTGTTTTACGCATTCGGTACCGGGCTGGGCGGGATGATTGGCCCGACGCT
GTTCGGCGAGCTGATTGAAACCGGCGAGCGCAGCAATGTGCTGATCGGCTATCTGATCGGAGCAGGGCTGATGCTGCTGG
CGGCGGTTGTGCAATCGATATGGGGCACGGCTGCCGAGCGCAAATCTCTGGAAGATGTGGCCAGACCGTTGTCGCAGGCC
GGGGACCGATAG

Upstream 100 bases:

>100_bases
GCGGCCAATCTGACGTTACTGTGGTTCTGGATCAGCTGAACTTGATCGGCTGCCGCGACTCTCACACCTGACACCAATGT
CAGCCGTCAGGTAGCCGGAC

Downstream 100 bases:

>100_bases
GGGCCTTTAGCGGAATATGCCGCGCAGGCTGTCCACGGACGCCCGCAGGCCGATGATTCGCTCACTGACCTCTTGCGCTT
CGTGTGCCCGGGAAGTTCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSTSSDKGTVFETDLPARLDRLPWGRFHTLLVVALGITWLLDGLEVTLAGSVAGALKASPALNLSNSDIGLAGAAYIAGA
VLGALFFGWLADRLGRRKLFFITLLLYVGATAATAFSFSMWSFMLFRFLTGMGIGGEYTAINSTIQEFTPARYRGWVDLT
INGTFWLGAALGAIGSIVLLDPLWVGAELGWRLCFGIGAVLGLLVLLMRLWLPESPRWLLIHGQAEQARQIVEQIEAGLQ
RQGHVLPAVSGKPLRLHARDHTPLGEVARTLLVTFRQRSLVGLTLLTAQAFFYNAIFFTYALVLTDFYDVPAERVGWYVL
PLALGNFCGPLLLGRLFDVVGRRVMISLTYGVSGVLLAISGYLFQQGVLDVTQQAIAWMVIFFFASAAASSAYLTVAETF
PLEIRALAIAVFYAFGTGLGGMIGPTLFGELIETGERSNVLIGYLIGAGLMLLAAVVQSIWGTAAERKSLEDVARPLSQA
GDR

Sequences:

>Translated_483_residues
MSTSSDKGTVFETDLPARLDRLPWGRFHTLLVVALGITWLLDGLEVTLAGSVAGALKASPALNLSNSDIGLAGAAYIAGA
VLGALFFGWLADRLGRRKLFFITLLLYVGATAATAFSFSMWSFMLFRFLTGMGIGGEYTAINSTIQEFTPARYRGWVDLT
INGTFWLGAALGAIGSIVLLDPLWVGAELGWRLCFGIGAVLGLLVLLMRLWLPESPRWLLIHGQAEQARQIVEQIEAGLQ
RQGHVLPAVSGKPLRLHARDHTPLGEVARTLLVTFRQRSLVGLTLLTAQAFFYNAIFFTYALVLTDFYDVPAERVGWYVL
PLALGNFCGPLLLGRLFDVVGRRVMISLTYGVSGVLLAISGYLFQQGVLDVTQQAIAWMVIFFFASAAASSAYLTVAETF
PLEIRALAIAVFYAFGTGLGGMIGPTLFGELIETGERSNVLIGYLIGAGLMLLAAVVQSIWGTAAERKSLEDVARPLSQA
GDR
>Mature_482_residues
STSSDKGTVFETDLPARLDRLPWGRFHTLLVVALGITWLLDGLEVTLAGSVAGALKASPALNLSNSDIGLAGAAYIAGAV
LGALFFGWLADRLGRRKLFFITLLLYVGATAATAFSFSMWSFMLFRFLTGMGIGGEYTAINSTIQEFTPARYRGWVDLTI
NGTFWLGAALGAIGSIVLLDPLWVGAELGWRLCFGIGAVLGLLVLLMRLWLPESPRWLLIHGQAEQARQIVEQIEAGLQR
QGHVLPAVSGKPLRLHARDHTPLGEVARTLLVTFRQRSLVGLTLLTAQAFFYNAIFFTYALVLTDFYDVPAERVGWYVLP
LALGNFCGPLLLGRLFDVVGRRVMISLTYGVSGVLLAISGYLFQQGVLDVTQQAIAWMVIFFFASAAASSAYLTVAETFP
LEIRALAIAVFYAFGTGLGGMIGPTLFGELIETGERSNVLIGYLIGAGLMLLAAVVQSIWGTAAERKSLEDVARPLSQAG
DR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI213021148, Length=229, Percent_Identity=27.0742358078603, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI7662270, Length=232, Percent_Identity=28.8793103448276, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI296080721, Length=246, Percent_Identity=26.0162601626016, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24308167, Length=474, Percent_Identity=24.4725738396624, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI296080719, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497499, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI296080734, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI203098995, Length=173, Percent_Identity=30.0578034682081, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI216548223, Length=247, Percent_Identity=27.9352226720648, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786229, Length=474, Percent_Identity=26.1603375527426, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788074, Length=410, Percent_Identity=29.7560975609756, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082159, Length=219, Percent_Identity=30.5936073059361, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788068, Length=480, Percent_Identity=26.25, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790550, Length=425, Percent_Identity=25.4117647058824, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789207, Length=398, Percent_Identity=23.3668341708543, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082231, Length=230, Percent_Identity=26.9565217391304, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790463, Length=218, Percent_Identity=25.6880733944954, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=441, Percent_Identity=25.6235827664399, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565978, Length=300, Percent_Identity=22.3333333333333, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565976, Length=281, Percent_Identity=23.4875444839858, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193202825, Length=289, Percent_Identity=23.8754325259516, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71986689, Length=289, Percent_Identity=23.8754325259516, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323512, Length=443, Percent_Identity=23.7020316027088, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320766, Length=376, Percent_Identity=25.2659574468085, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323653, Length=382, Percent_Identity=25.6544502617801, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324400, Length=376, Percent_Identity=25.2659574468085, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322618, Length=381, Percent_Identity=24.6719160104987, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319956, Length=381, Percent_Identity=24.6719160104987, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321888, Length=377, Percent_Identity=22.0159151193634, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321100, Length=379, Percent_Identity=25.5936675461741, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321886, Length=372, Percent_Identity=21.2365591397849, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640198, Length=485, Percent_Identity=24.1237113402062, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640196, Length=485, Percent_Identity=24.1237113402062, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640200, Length=485, Percent_Identity=24.1237113402062, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922874, Length=450, Percent_Identity=25.1111111111111, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221330907, Length=172, Percent_Identity=30.8139534883721, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356505, Length=359, Percent_Identity=25.0696378830084, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161077756, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24652793, Length=466, Percent_Identity=23.175965665236, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652795, Length=423, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52181; Mature: 52050

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSSDKGTVFETDLPARLDRLPWGRFHTLLVVALGITWLLDGLEVTLAGSVAGALKASP
CCCCCCCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
ALNLSNSDIGLAGAAYIAGAVLGALFFGWLADRLGRRKLFFITLLLYVGATAATAFSFSM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WSFMLFRFLTGMGIGGEYTAINSTIQEFTPARYRGWVDLTINGTFWLGAALGAIGSIVLL
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHH
DPLWVGAELGWRLCFGIGAVLGLLVLLMRLWLPESPRWLLIHGQAEQARQIVEQIEAGLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
RQGHVLPAVSGKPLRLHARDHTPLGEVARTLLVTFRQRSLVGLTLLTAQAFFYNAIFFTY
HCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVLTDFYDVPAERVGWYVLPLALGNFCGPLLLGRLFDVVGRRVMISLTYGVSGVLLAIS
HHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
GYLFQQGVLDVTQQAIAWMVIFFFASAAASSAYLTVAETFPLEIRALAIAVFYAFGTGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
GMIGPTLFGELIETGERSNVLIGYLIGAGLMLLAAVVQSIWGTAAERKSLEDVARPLSQA
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GDR
CCC
>Mature Secondary Structure 
STSSDKGTVFETDLPARLDRLPWGRFHTLLVVALGITWLLDGLEVTLAGSVAGALKASP
CCCCCCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
ALNLSNSDIGLAGAAYIAGAVLGALFFGWLADRLGRRKLFFITLLLYVGATAATAFSFSM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WSFMLFRFLTGMGIGGEYTAINSTIQEFTPARYRGWVDLTINGTFWLGAALGAIGSIVLL
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCEEEEEECCHHHHHHHHHHHHHHHHH
DPLWVGAELGWRLCFGIGAVLGLLVLLMRLWLPESPRWLLIHGQAEQARQIVEQIEAGLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHH
RQGHVLPAVSGKPLRLHARDHTPLGEVARTLLVTFRQRSLVGLTLLTAQAFFYNAIFFTY
HCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVLTDFYDVPAERVGWYVLPLALGNFCGPLLLGRLFDVVGRRVMISLTYGVSGVLLAIS
HHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
GYLFQQGVLDVTQQAIAWMVIFFFASAAASSAYLTVAETFPLEIRALAIAVFYAFGTGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
GMIGPTLFGELIETGERSNVLIGYLIGAGLMLLAAVVQSIWGTAAERKSLEDVARPLSQA
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GDR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]