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The map label for this gene is btuB [H]

Identifier: 66045530

GI number: 66045530

Start: 2659700

End: 2662102

Strand: Direct

Name: btuB [H]

Synonym: Psyr_2290

Alternate gene names: 66045530

Gene position: 2659700-2662102 (Clockwise)

Preceding gene: 66045529

Following gene: 66045531

Centisome position: 43.65

GC content: 59.38

Gene sequence:

>2403_bases
ATGGGGAATTTCAAACGCAGTGTATTGGCCACGGCGATTTTTTCAGCCAATTTGCTGAGCGTCGCGGGCATCAGTGCAAG
TGCATTCGCCGCAGAAGCGACAGATGAAGCAAACACTCAGGGTGCGTCCACCCTGGGTACAGTGATCGTGACCGGCACCC
GTGCGCAGGAGCGTACCGCCAGCGCCTCGCTGTCGCCTATCGATGTGATTTCCGGTGACAGCCTGCGCAGTTCCGGCTCC
AGCGAACTGGGCACCGTGCTGGCACGTTTGATCCCTTCGATCAATTTCCCCCGGCCGAGCCTGGTGGACGGTGCGGAGCT
GACGCGTCCGGCGCAACTGCGCGGCCTGTCGCCGGATCAGGTGCTGGTGCTGGTCAATGGCAAGCGCCGCCATACATCCG
CCTTCGTCAATCTGGGCGGGGCGGTCGGACGCGGTTCGGCACCTGCCGACCTGAATGCCATCCCGCTGTCGGCCATCGAC
CATATCGAAGTCCTGCGCGACGGTGCGTCGGCACGTTACGGGTCCGATGCCATCGCCGGGGTGATCAACATCATTCTCAA
AAGCGCCGACCACGGCGGGTCGATTTCCAGCCAGTACGGCCAATACAAGAAGGGCGACGGGATCCAGCGCCAGGTGTCGG
GCAATACCGGTTTTGCTTTAGGCGACAATGGCACGTTCAACCTTTCCGGTGAAGGTGCCAACAATGACTACACCAACCGT
GCCGGTGACGACTTTCGAGCGTCCAGTGTCGGGTCCACCACTTACGGTCAGCAGGTGTTTCGCCAGGGCGAGCCACAGAC
GCACGAGGGCAAGCTGCAGTACAACGCTGAATACAGCTTCAATGATGCGGCGGAGTTCTATAGCTTCGGGGGCTACAGCA
AGAGGCGTGGCGAAACCGCCGGATTTTATCGGCCGAGCAATGCCTCGAATAACATTGCGGCGATTTATCCCAACGGCTAT
CTGCCGCTGATCAATGGCACGCTCGAAGACATCTCGCTGGTCGCGGGCCTGCGCGGAGAGCTGGCGTATGACTGGCACTA
CGACGTGTCCGCCAACTATGGCAAAAACTCCTATGAGCTGCGCACCAAAACCATCAACACCTCATTGGGACTGAACACGC
CGCGCTCGTTCTACAACGGCACGCTGACCAATGATCAGAAGCAACTGAGCCTCGATCTGTCTAGAGAATTCAATACAGCG
TGGTTGCCTTACCCGGTATCGGTTGCGTTTGGCGCGGAATACCTGCGTCAGGGCTATCAGATCGAGGCAGGGCAAGCGGA
GTCGTATTTCCAGACCGGCAGTTCCGGGCTGGGCGGTTTCCGTGCGGCGGATGCCGGCAGTTACTCGCGACACAACTTCG
CCCAGTATCTGGACCTGGAAACCAATCTGACCGAGAAACTGGGCGTGTCGGCGGCCGTTCGCCACGAGGACTACAGCGAT
TTCGGCTCCAATGTCAGCGGTTCACTCTCGGCGCGCTACGATTTCACTCCGCAGGTGGCCTTGCGAGGCAGCGTATCGAC
AGGCTTCCGCGCGCCTTCGCTGGCGCAGCAGAATTTTGCCTTCACGTCGTCGCAGCTGATTGGCAACACCCTCCAGGAAG
CGGGCACGTTTCCGGCCGGCAGTAACGTTGCACAACTGTTGGGCGCCGAAGACCTCAAACCGGAAAAGTCCCGTAACTAC
AGCCTTGGCCTGGTACTCCAGCCGCTGAACAGCCTGACCTTGACTGCCGACGTCTATCGCATCGACATTCAGGACCGTAT
CTCGCTGTCTTCCAATCTGGTGCTCAATGACACCGCCATCAATTACCTGCGCAGCAATGGCGTAGGCGATATCAACTACA
CCAGTGCCCGCTATTTCACCAACGCCACGGACACCAGCACCGATGGCGTCGATCTGGTCGCCAGTTACCGCTATCAGTTC
GACAACGGCGTGCGCTGGAACAGCACGGTGGGTTACAACTACAACCACACCAAAGTCACCGACGTGAAGGCCAACCCGGC
GATTCTCGATCAGTTGGGGGTGAATCTGGTACGGGTAGACCGCAGGGAACGCATCGGTTTGCTGGGCGACACCACGCCAC
AACACAAACTGACACTGGGCAATGACCTGACGTTCGGTAACTGGGCGTTGCACTCCAACCTGGTCCGCTACGGCGAGTTC
ACCAGCTATCAGGCCGACAAGGTCAACGACCAGACCTTCAGCGCCGCCTGGCTGCTGGACCTGGCGGTCGACTACAAGCT
CAAGAGCTGGGTCTTCACCCTGGGCGGCGACAACGTCACCGACAAATACCCGGAGAAGCTCAACGACTTCTCCTCCAGCG
GCGGCAACCTGGCCTACAGCACGTTCTCACCCTACGGGTACAGCGGCGCTTATTACTACGGCAAGGTCACGTATAACTGG
TAG

Upstream 100 bases:

>100_bases
ATTAATCAGACACCGTAATGATCGCCACCGTCCGCCGCACGGATCGCTCGTTGTAACCAGAACAGAGTTTCTGGATCAGG
GATTTTCAAGGGGTAGTGGT

Downstream 100 bases:

>100_bases
CGCGATTTGCCGCTGACTGTCGTTCCAATGCGTTGAGTTTGTATAAAGCTCGTGACGCTGCAACACGACGCTATGCCTTG
CTCCTGGGCACTGCACATAA

Product: TonB-dependent receptor:TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 800; Mature: 799

Protein sequence:

>800_residues
MGNFKRSVLATAIFSANLLSVAGISASAFAAEATDEANTQGASTLGTVIVTGTRAQERTASASLSPIDVISGDSLRSSGS
SELGTVLARLIPSINFPRPSLVDGAELTRPAQLRGLSPDQVLVLVNGKRRHTSAFVNLGGAVGRGSAPADLNAIPLSAID
HIEVLRDGASARYGSDAIAGVINIILKSADHGGSISSQYGQYKKGDGIQRQVSGNTGFALGDNGTFNLSGEGANNDYTNR
AGDDFRASSVGSTTYGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETAGFYRPSNASNNIAAIYPNGY
LPLINGTLEDISLVAGLRGELAYDWHYDVSANYGKNSYELRTKTINTSLGLNTPRSFYNGTLTNDQKQLSLDLSREFNTA
WLPYPVSVAFGAEYLRQGYQIEAGQAESYFQTGSSGLGGFRAADAGSYSRHNFAQYLDLETNLTEKLGVSAAVRHEDYSD
FGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFAFTSSQLIGNTLQEAGTFPAGSNVAQLLGAEDLKPEKSRNY
SLGLVLQPLNSLTLTADVYRIDIQDRISLSSNLVLNDTAINYLRSNGVGDINYTSARYFTNATDTSTDGVDLVASYRYQF
DNGVRWNSTVGYNYNHTKVTDVKANPAILDQLGVNLVRVDRRERIGLLGDTTPQHKLTLGNDLTFGNWALHSNLVRYGEF
TSYQADKVNDQTFSAAWLLDLAVDYKLKSWVFTLGGDNVTDKYPEKLNDFSSSGGNLAYSTFSPYGYSGAYYYGKVTYNW

Sequences:

>Translated_800_residues
MGNFKRSVLATAIFSANLLSVAGISASAFAAEATDEANTQGASTLGTVIVTGTRAQERTASASLSPIDVISGDSLRSSGS
SELGTVLARLIPSINFPRPSLVDGAELTRPAQLRGLSPDQVLVLVNGKRRHTSAFVNLGGAVGRGSAPADLNAIPLSAID
HIEVLRDGASARYGSDAIAGVINIILKSADHGGSISSQYGQYKKGDGIQRQVSGNTGFALGDNGTFNLSGEGANNDYTNR
AGDDFRASSVGSTTYGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETAGFYRPSNASNNIAAIYPNGY
LPLINGTLEDISLVAGLRGELAYDWHYDVSANYGKNSYELRTKTINTSLGLNTPRSFYNGTLTNDQKQLSLDLSREFNTA
WLPYPVSVAFGAEYLRQGYQIEAGQAESYFQTGSSGLGGFRAADAGSYSRHNFAQYLDLETNLTEKLGVSAAVRHEDYSD
FGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFAFTSSQLIGNTLQEAGTFPAGSNVAQLLGAEDLKPEKSRNY
SLGLVLQPLNSLTLTADVYRIDIQDRISLSSNLVLNDTAINYLRSNGVGDINYTSARYFTNATDTSTDGVDLVASYRYQF
DNGVRWNSTVGYNYNHTKVTDVKANPAILDQLGVNLVRVDRRERIGLLGDTTPQHKLTLGNDLTFGNWALHSNLVRYGEF
TSYQADKVNDQTFSAAWLLDLAVDYKLKSWVFTLGGDNVTDKYPEKLNDFSSSGGNLAYSTFSPYGYSGAYYYGKVTYNW
>Mature_799_residues
GNFKRSVLATAIFSANLLSVAGISASAFAAEATDEANTQGASTLGTVIVTGTRAQERTASASLSPIDVISGDSLRSSGSS
ELGTVLARLIPSINFPRPSLVDGAELTRPAQLRGLSPDQVLVLVNGKRRHTSAFVNLGGAVGRGSAPADLNAIPLSAIDH
IEVLRDGASARYGSDAIAGVINIILKSADHGGSISSQYGQYKKGDGIQRQVSGNTGFALGDNGTFNLSGEGANNDYTNRA
GDDFRASSVGSTTYGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETAGFYRPSNASNNIAAIYPNGYL
PLINGTLEDISLVAGLRGELAYDWHYDVSANYGKNSYELRTKTINTSLGLNTPRSFYNGTLTNDQKQLSLDLSREFNTAW
LPYPVSVAFGAEYLRQGYQIEAGQAESYFQTGSSGLGGFRAADAGSYSRHNFAQYLDLETNLTEKLGVSAAVRHEDYSDF
GSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFAFTSSQLIGNTLQEAGTFPAGSNVAQLLGAEDLKPEKSRNYS
LGLVLQPLNSLTLTADVYRIDIQDRISLSSNLVLNDTAINYLRSNGVGDINYTSARYFTNATDTSTDGVDLVASYRYQFD
NGVRWNSTVGYNYNHTKVTDVKANPAILDQLGVNLVRVDRRERIGLLGDTTPQHKLTLGNDLTFGNWALHSNLVRYGEFT
SYQADKVNDQTFSAAWLLDLAVDYKLKSWVFTLGGDNVTDKYPEKLNDFSSSGGNLAYSTFSPYGYSGAYYYGKVTYNW

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=589, Percent_Identity=25.1273344651952, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790405, Length=516, Percent_Identity=25.7751937984496, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788478, Length=141, Percent_Identity=35.4609929078014, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86355; Mature: 86224

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.1 %Met     (Translated Protein)
0.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFKRSVLATAIFSANLLSVAGISASAFAAEATDEANTQGASTLGTVIVTGTRAQERTA
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCEEEEEEECCCCHHHHH
SASLSPIDVISGDSLRSSGSSELGTVLARLIPSINFPRPSLVDGAELTRPAQLRGLSPDQ
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHCCCCCCC
VLVLVNGKRRHTSAFVNLGGAVGRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAG
EEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
VINIILKSADHGGSISSQYGQYKKGDGIQRQVSGNTGFALGDNGTFNLSGEGANNDYTNR
HHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEECCCCEEEEECCCCCCCCCCC
AGDDFRASSVGSTTYGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETA
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCC
GFYRPSNASNNIAAIYPNGYLPLINGTLEDISLVAGLRGELAYDWHYDVSANYGKNSYEL
CEECCCCCCCCEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEE
RTKTINTSLGLNTPRSFYNGTLTNDQKQLSLDLSREFNTAWLPYPVSVAFGAEYLRQGYQ
EEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCEECCCCEEHHHHHHHHHCCCE
IEAGQAESYFQTGSSGLGGFRAADAGSYSRHNFAQYLDLETNLTEKLGVSAAVRHEDYSD
EECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCHHHHCCEEEEECCCHHH
FGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFAFTSSQLIGNTLQEAGTFPAG
HCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SNVAQLLGAEDLKPEKSRNYSLGLVLQPLNSLTLTADVYRIDIQDRISLSSNLVLNDTAI
CHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECHHHHCCCCCEEEEHHHH
NYLRSNGVGDINYTSARYFTNATDTSTDGVDLVASYRYQFDNGVRWNSTVGYNYNHTKVT
HHHHCCCCCCCEECCEEEEECCCCCCCCCEEEEEEEEEECCCCCEECCEECCCCCCCEEE
DVKANPAILDQLGVNLVRVDRRERIGLLGDTTPQHKLTLGNDLTFGNWALHSNLVRYGEF
EECCCCHHHHHHCCEEEEECCHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
TSYQADKVNDQTFSAAWLLDLAVDYKLKSWVFTLGGDNVTDKYPEKLNDFSSSGGNLAYS
CCCCCCCCCCCHHHHEEEEEHHHCEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEE
TFSPYGYSGAYYYGKVTYNW
ECCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
GNFKRSVLATAIFSANLLSVAGISASAFAAEATDEANTQGASTLGTVIVTGTRAQERTA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCCEEEEEEECCCCHHHHH
SASLSPIDVISGDSLRSSGSSELGTVLARLIPSINFPRPSLVDGAELTRPAQLRGLSPDQ
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHCCCCCCC
VLVLVNGKRRHTSAFVNLGGAVGRGSAPADLNAIPLSAIDHIEVLRDGASARYGSDAIAG
EEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
VINIILKSADHGGSISSQYGQYKKGDGIQRQVSGNTGFALGDNGTFNLSGEGANNDYTNR
HHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEECCCCEEEEECCCCCCCCCCC
AGDDFRASSVGSTTYGQQVFRQGEPQTHEGKLQYNAEYSFNDAAEFYSFGGYSKRRGETA
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCCC
GFYRPSNASNNIAAIYPNGYLPLINGTLEDISLVAGLRGELAYDWHYDVSANYGKNSYEL
CEECCCCCCCCEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEE
RTKTINTSLGLNTPRSFYNGTLTNDQKQLSLDLSREFNTAWLPYPVSVAFGAEYLRQGYQ
EEEEEECCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCEECCCCEEHHHHHHHHHCCCE
IEAGQAESYFQTGSSGLGGFRAADAGSYSRHNFAQYLDLETNLTEKLGVSAAVRHEDYSD
EECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCHHHHCCEEEEECCCHHH
FGSNVSGSLSARYDFTPQVALRGSVSTGFRAPSLAQQNFAFTSSQLIGNTLQEAGTFPAG
HCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
SNVAQLLGAEDLKPEKSRNYSLGLVLQPLNSLTLTADVYRIDIQDRISLSSNLVLNDTAI
CHHHHHHCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECHHHHCCCCCEEEEHHHH
NYLRSNGVGDINYTSARYFTNATDTSTDGVDLVASYRYQFDNGVRWNSTVGYNYNHTKVT
HHHHCCCCCCCEECCEEEEECCCCCCCCCEEEEEEEEEECCCCCEECCEECCCCCCCEEE
DVKANPAILDQLGVNLVRVDRRERIGLLGDTTPQHKLTLGNDLTFGNWALHSNLVRYGEF
EECCCCHHHHHHCCEEEEECCHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCC
TSYQADKVNDQTFSAAWLLDLAVDYKLKSWVFTLGGDNVTDKYPEKLNDFSSSGGNLAYS
CCCCCCCCCCCHHHHEEEEEHHHCEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEE
TFSPYGYSGAYYYGKVTYNW
ECCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA