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The map label for this gene is exbB [H]

Identifier: 66045528

GI number: 66045528

Start: 2658248

End: 2659015

Strand: Direct

Name: exbB [H]

Synonym: Psyr_2288

Alternate gene names: 66045528

Gene position: 2658248-2659015 (Clockwise)

Preceding gene: 66045527

Following gene: 66045529

Centisome position: 43.62

GC content: 62.63

Gene sequence:

>768_bases
ATGCCTTGTTCAGACTTTGTTCATAGAGAGAGCTGCGCCATGAACCTGATTGCTTCGCCTTTTGAATCCATCGAACACGC
GGTCATCTGGCTGCTGGTCATTTTTTCCGTCGCGACCTGGGGCCTGGCCCTGCTCAAGGGCGTGCAGTTTTCGCGCCTGA
AGTCTCAGGATCGCAAGTTCCACAAGCAGTTCTGGGCGGCATCGAGCTTGGATTCAGCCGCGCAACTGGCCCACGAGCAA
CCGGGCGCTGCCGCTCGGGTCGCGCTGGCCGGTTACGCCGCCATTCAGGTGGCGGATGGCGCGCAGGCCCATGACCTCAG
TCAGTCCATCAACCATCAGGACCGCCTTGAGCGCGCCCTGCGTCAGCAGATCGTCCGCGAGCGCCGCTCGCTGGAAACCG
GTCTGGCCATCCTCGCCAGCATCGGCAGCACTTCGCCTTTCATCGGTCTGTTCGGTACGGTCTGGGGCATCATGTCGGCC
CTCAAGGGCATCAGTGCGGCCGGTTCCGCGAGCCTGGAAACGGTGGCCGGGCCGATCGGCGCGGCGCTGGTGGCAACCGG
TGTCGGCATTGCCGTCGCAGTGCCTGCAGTGCTGGTCTACAACTACTTTCTGCGACGCCTGAAACTGACGGCTGCCGATC
TGGATGACTTTGCCCATGACTTCTATAGCCTGGCGCAGAAGAGTGCCTTCCGTGTGCTGCTGCATCCGGTATTGAAGTCC
GGCGCTGCAGGCGCACACGCCGGGCAGAAAGTGCAGGAGGCCTCCTGA

Upstream 100 bases:

>100_bases
CAAATGAGGCTTCAAGATCAAATAACGTTTCAAGATCAAACCCGGCTATTCGAATGACCTGGCGAGCTACCTGAACCAAA
GGCGCATCGCGACACAACCC

Downstream 100 bases:

>100_bases
GATGGCTTTTTCCACGCAAGACACCGATGAAGTGCTGAGCGAGATCAACGTCACGCCGCTGGTAGACGTGATGCTGGTGC
TGCTGGTGGTGTTCATCGTT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MPCSDFVHRESCAMNLIASPFESIEHAVIWLLVIFSVATWGLALLKGVQFSRLKSQDRKFHKQFWAASSLDSAAQLAHEQ
PGAAARVALAGYAAIQVADGAQAHDLSQSINHQDRLERALRQQIVRERRSLETGLAILASIGSTSPFIGLFGTVWGIMSA
LKGISAAGSASLETVAGPIGAALVATGVGIAVAVPAVLVYNYFLRRLKLTAADLDDFAHDFYSLAQKSAFRVLLHPVLKS
GAAGAHAGQKVQEAS

Sequences:

>Translated_255_residues
MPCSDFVHRESCAMNLIASPFESIEHAVIWLLVIFSVATWGLALLKGVQFSRLKSQDRKFHKQFWAASSLDSAAQLAHEQ
PGAAARVALAGYAAIQVADGAQAHDLSQSINHQDRLERALRQQIVRERRSLETGLAILASIGSTSPFIGLFGTVWGIMSA
LKGISAAGSASLETVAGPIGAALVATGVGIAVAVPAVLVYNYFLRRLKLTAADLDDFAHDFYSLAQKSAFRVLLHPVLKS
GAAGAHAGQKVQEAS
>Mature_254_residues
PCSDFVHRESCAMNLIASPFESIEHAVIWLLVIFSVATWGLALLKGVQFSRLKSQDRKFHKQFWAASSLDSAAQLAHEQP
GAAARVALAGYAAIQVADGAQAHDLSQSINHQDRLERALRQQIVRERRSLETGLAILASIGSTSPFIGLFGTVWGIMSAL
KGISAAGSASLETVAGPIGAALVATGVGIAVAVPAVLVYNYFLRRLKLTAADLDDFAHDFYSLAQKSAFRVLLHPVLKSG
AAGAHAGQKVQEAS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=208, Percent_Identity=30.2884615384615, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789381, Length=187, Percent_Identity=33.1550802139037, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 27087; Mature: 26956

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHCCHHHCCC
>Mature Secondary Structure 
PCSDFVHRESCAMNLIASPFESIEHAVIWLLVIFSVATWGLALLKGVQFSRLKSQDRKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKQFWAASSLDSAAQLAHEQPGAAARVALAGYAAIQVADGAQAHDLSQSINHQDRLERAL
HHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHCCHHHHHHHHH
RQQIVRERRSLETGLAILASIGSTSPFIGLFGTVWGIMSALKGISAAGSASLETVAGPIG
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AALVATGVGIAVAVPAVLVYNYFLRRLKLTAADLDDFAHDFYSLAQKSAFRVLLHPVLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAAGAHAGQKVQEAS
CCCCCHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]