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The map label for this gene is infC [H]

Identifier: 66045403

GI number: 66045403

Start: 2517675

End: 2518208

Strand: Direct

Name: infC [H]

Synonym: Psyr_2163

Alternate gene names: 66045403

Gene position: 2517675-2518208 (Clockwise)

Preceding gene: 66045402

Following gene: 66045404

Centisome position: 41.32

GC content: 52.81

Gene sequence:

>534_bases
ATGAGACAAGATAAACGAGCTGCACCCAAGGCCCCGATCAATGAAAATATCTCGGCCCGCGAGGTTCGTTTAATTGGCGC
TGACGGCGAGCAGATTGGCATCGTCTCGATTGATGAAGCGCTTCGTATTGCCGAAGAGGCGAAGCTGGATCTGGTAGAGA
TTTCTGCCGACGCAGTCCCTCCGGTCTGCCGTGTGATGGATTACGGCAAATCGATCTTCGAGAAGAAGAAGCAGGTTGCT
GCAGCGAAGAAGAACCAGAAGCAGATCCAGGTTAAAGAAATCAAGTTTCGTCCAGGGACGGAGGAAGGGGATTACCAGGT
AAAACTACGCAACCTGGTACGTTTCCTGAGTGACGGGGACAGGGCCAAGGTATCGTTGAGATTCCGCGGTCGTGAGATGG
CCCACCAGGAGCTGGGTATGGAGCTGTTGAAGCGGGTTGAAGGTGACCTGCTCGAATACGGTTCCGTCGAACAGCATCCT
AAGATGGAAGGACGCCAGCTGATCATGGTCATCGCCCCGAAAAAGAAGAAATAA

Upstream 100 bases:

>100_bases
ACCTTGGCTCGATGCCGGTCGCCCAATTCGCTGAATTCCTCGCACAAGCGGTTTCCCGGCGTGGTCGCCAAGATACGGAG
TAATTATTATTAAGCGTGAA

Downstream 100 bases:

>100_bases
CCACCAGGGCACGGCAGGCCTTGCGGTTATATTTATCAACTGAATGCGGAGTATCCGAACATGCCAAAGATGAAGACTAA
AAGTGGTGCAGCTAAGCGGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQVA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK

Sequences:

>Translated_177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQVA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK
>Mature_177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQVA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=180, Percent_Identity=64.4444444444444, Blast_Score=211, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20036; Mature: 20036

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVP
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHCCEEEEECCCCCC
PVCRVMDYGKSIFEKKKQVAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEHHHHHHHHHCCCC
RAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHPKMEGRQLIMVIAPKKKK
CEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVP
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHCCEEEEECCCCCC
PVCRVMDYGKSIFEKKKQVAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEHHHHHHHHHCCCC
RAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHPKMEGRQLIMVIAPKKKK
CEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA