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The map label for this gene is rbsK [H]

Identifier: 66045395

GI number: 66045395

Start: 2511267

End: 2512187

Strand: Direct

Name: rbsK [H]

Synonym: Psyr_2155

Alternate gene names: 66045395

Gene position: 2511267-2512187 (Clockwise)

Preceding gene: 66045394

Following gene: 66045396

Centisome position: 41.21

GC content: 62.54

Gene sequence:

>921_bases
ATGCAAGCAAAAATAGTGATAGTAGGCAGTCTGAACATGGATCTGGTCATCCGCGCCCAGCGTCTGCCACGTCCTGGCGA
GACCTTGAGCGGGGAGACATTCGACACCGTGCCTGGCGGCAAAGGCGCCAATCAGGCGGTCGCTGCGGCACGTCTTGGCG
CCAGTGTGGCAATGATCGGTTGTGTCGGGGCGGATGCCTACGGCGAACAACTGCGTGCAGCGCTGCTGGCCGAGCAGATC
GATTGTCAGGCGGTGACCGTCGTTGAGGGGGTGTCCACCGGGATCGCCTCGATCGTGGTCGACGCCAACAGCCAGAACGC
CATTGTCATCGTGGCCGGTGGCAATGGTCGGCTCACTCCGGCATTGCTCGAGCGCTTCGACGCGCTGCTGGCAGATTCGC
AAATCGTCATCTGCCAGCTCGAAGTGCCGACCGAAACCGTTTTCCACACCCTGGCCCGCGCCCGTGCGCTGGGCAAGACC
GTCATTCTCAATCCTGCCCCGGCCAGCGAGCCCTTGCCGGCAAGCTGGTATGCCCTGATCGACTACCTGATCCCCAATGA
AAGCGAAGCGCAGACCCTGACCGGTGTGAACGTCGACTCGCCGGCTGCCGCTGAAAATGCGGCATCGGTCATGCTGGCGG
CCGGCGCGCGCAACGTGATCATTACCCTCGGCGAGCACGGAACCCTGTTCGCCAATGCTTCTGGCATGGATCATATTCCC
GCGCGACGCGTGCAGGCCGTGGACACCACCGCTGCAGGTGATACCTTTGTCGGCGGTTTTGCGGCGGCGCTGTCCGCAGG
CCATGGCGAATTGCAGGCAATTCGTTTCGGTCAGGCTGCGGCGGCCATCTCCGTTACCCGAGCAGGTGCCCAGCCGTCCA
TCCCGACGTTCGAGGAAGTACAGGAATTCAATTCGCTATGA

Upstream 100 bases:

>100_bases
AAGGCTCGTGACGCCCAGCGTCGTGGTGCGCGAGTCTACGGCAGCGCCAAACACTTTATCCAACGAATGACGCGCAAGCA
CAGCAACGGATTAATCAGCC

Downstream 100 bases:

>100_bases
AAAAGACCCCGCTACTCAATATTGCCCTGTCCCGCGTGATTGCATCGCTGGGTCACGGTGACATCCTGATGATCGTCGAC
GCCGGCATGCCAGTACCGGC

Product: carbohydrate kinase, PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MQAKIVIVGSLNMDLVIRAQRLPRPGETLSGETFDTVPGGKGANQAVAAARLGASVAMIGCVGADAYGEQLRAALLAEQI
DCQAVTVVEGVSTGIASIVVDANSQNAIVIVAGGNGRLTPALLERFDALLADSQIVICQLEVPTETVFHTLARARALGKT
VILNPAPASEPLPASWYALIDYLIPNESEAQTLTGVNVDSPAAAENAASVMLAAGARNVIITLGEHGTLFANASGMDHIP
ARRVQAVDTTAAGDTFVGGFAAALSAGHGELQAIRFGQAAAAISVTRAGAQPSIPTFEEVQEFNSL

Sequences:

>Translated_306_residues
MQAKIVIVGSLNMDLVIRAQRLPRPGETLSGETFDTVPGGKGANQAVAAARLGASVAMIGCVGADAYGEQLRAALLAEQI
DCQAVTVVEGVSTGIASIVVDANSQNAIVIVAGGNGRLTPALLERFDALLADSQIVICQLEVPTETVFHTLARARALGKT
VILNPAPASEPLPASWYALIDYLIPNESEAQTLTGVNVDSPAAAENAASVMLAAGARNVIITLGEHGTLFANASGMDHIP
ARRVQAVDTTAAGDTFVGGFAAALSAGHGELQAIRFGQAAAAISVTRAGAQPSIPTFEEVQEFNSL
>Mature_306_residues
MQAKIVIVGSLNMDLVIRAQRLPRPGETLSGETFDTVPGGKGANQAVAAARLGASVAMIGCVGADAYGEQLRAALLAEQI
DCQAVTVVEGVSTGIASIVVDANSQNAIVIVAGGNGRLTPALLERFDALLADSQIVICQLEVPTETVFHTLARARALGKT
VILNPAPASEPLPASWYALIDYLIPNESEAQTLTGVNVDSPAAAENAASVMLAAGARNVIITLGEHGTLFANASGMDHIP
ARRVQAVDTTAAGDTFVGGFAAALSAGHGELQAIRFGQAAAAISVTRAGAQPSIPTFEEVQEFNSL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=40.7407407407407, Blast_Score=185, Evalue=5e-47,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=46.3333333333333, Blast_Score=220, Evalue=7e-59,
Organism=Escherichia coli, GI87081971, Length=276, Percent_Identity=29.3478260869565, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082343, Length=313, Percent_Identity=30.0319488817891, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789775, Length=259, Percent_Identity=28.957528957529, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788491, Length=286, Percent_Identity=22.3776223776224, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788484, Length=308, Percent_Identity=26.2987012987013, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=40.3973509933775, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=32.7272727272727, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=37.171052631579, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=33.1168831168831, Blast_Score=154, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31333; Mature: 31333

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKIVIVGSLNMDLVIRAQRLPRPGETLSGETFDTVPGGKGANQAVAAARLGASVAMIG
CCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCEEEEE
CVGADAYGEQLRAALLAEQIDCQAVTVVEGVSTGIASIVVDANSQNAIVIVAGGNGRLTP
EECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCCEEEEEEECCCCCEEEEEECCCCCCCH
ALLERFDALLADSQIVICQLEVPTETVFHTLARARALGKTVILNPAPASEPLPASWYALI
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
DYLIPNESEAQTLTGVNVDSPAAAENAASVMLAAGARNVIITLGEHGTLFANASGMDHIP
HHHCCCCCCCCEEECCCCCCCCCHHHHHEEEEECCCCEEEEEECCCCEEEECCCCCCCCC
ARRVQAVDTTAAGDTFVGGFAAALSAGHGELQAIRFGQAAAAISVTRAGAQPSIPTFEEV
HHHHEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEECCCCCCCCCHHHH
QEFNSL
HHHHCC
>Mature Secondary Structure
MQAKIVIVGSLNMDLVIRAQRLPRPGETLSGETFDTVPGGKGANQAVAAARLGASVAMIG
CCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCEEEEE
CVGADAYGEQLRAALLAEQIDCQAVTVVEGVSTGIASIVVDANSQNAIVIVAGGNGRLTP
EECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCCEEEEEEECCCCCEEEEEECCCCCCCH
ALLERFDALLADSQIVICQLEVPTETVFHTLARARALGKTVILNPAPASEPLPASWYALI
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
DYLIPNESEAQTLTGVNVDSPAAAENAASVMLAAGARNVIITLGEHGTLFANASGMDHIP
HHHCCCCCCCCEEECCCCCCCCCHHHHHEEEEECCCCEEEEEECCCCEEEECCCCCCCCC
ARRVQAVDTTAAGDTFVGGFAAALSAGHGELQAIRFGQAAAAISVTRAGAQPSIPTFEEV
HHHHEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHEEEEEECCCCCCCCCHHHH
QEFNSL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]