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The map label for this gene is yaeL [C]

Identifier: 66044598

GI number: 66044598

Start: 1529409

End: 1530761

Strand: Direct

Name: yaeL [C]

Synonym: Psyr_1350

Alternate gene names: 66044598

Gene position: 1529409-1530761 (Clockwise)

Preceding gene: 66044597

Following gene: 66044599

Centisome position: 25.1

GC content: 60.83

Gene sequence:

>1353_bases
ATGAGCGCTTTATACATGATTCTCGGCACCCTGATTGCTCTGGGTGTGCTGGTGACCTTCCACGAATTCGGCCACTTCTG
GGTGGCGCGCCGCTGTGGCGTCAAGGTGCTGCGTTTCTCGGTAGGCTTCGGCACGCCTCTGCTGCGCTGGCATGACCGGC
AGGGCACCGAGTACGTCGTCGCTGCCATTCCTCTGGGCGGCTATGTGAAGATGCTCGACGAGCGCGAAGGCAATGTTCCG
CCCGAACTCGCTGACCAGTCGTTCAACCGCAAGACAGTAGGGCAGCGCATCGCGATCGTGATTGCCGGCCCGACTGCCAA
TTTCATCCTGGCCATCGCATTTTTCTGGGTGCTGGCGATGATGGGCAGCGAGCAGGTGCGCCCCGTTATCGGCGCAGTCG
AGTCCGGAAGCATCGCCCAGCAGGCTGGCCTGACGGCCGGACAGGAAATCGTTGCTGTCGATGGCGAGCCTACTTCGGGT
TGGGCCGGGGTCAATCTGCAACTGGTCCGCCGTCTGGGTGAAAGCGGTACCATCGCGTTGAAAGTCAGGGACCAGGGTTC
TACGGTCGACACGTCTCGTCAGTTGGTACTGAGTGACTGGCTGAGAGGCGCAGAAGAGCCTGATCCGATCAAGTCGCTGG
GTATTCGCCCGTGGCGTCCGGCGCTGTTGCCGGTGCTGGCGGAAATCGATCCGAAAGGTCCGGCGCAGAGCGCAGGGCTC
AAAACGGGTGATCGTCTCGTTGCGATGGACGGTCAGCCGCTCGATGAGTGGCAACAGGTTGTCGATCGGGTGCGCGAGCG
TCCCGAAGCGAAGATTTCGCTGCGCATCGAGCGCGACGGGGTGCAAATGGACGTGCCGGTGACCCTCGCGGCCAAGGGCG
AGGGCAAGGCTGCCGCGGGTTACCTGGGGGCTGGTGTGAAAGCTGTCGATTGGCCACCGGAAATGCTGCGCGAGGTCAGC
TACGGGCCTTTCGCGGCGATGGCCGAGGGTGTGAAGCGCACCTGGAACATGAGTGTGCTGACCCTGGACTCGCTGAAGAA
AATGTTGTTCGGCGAGCTCTCGGTAAAAAACTTGAGTGGACCGATAACCATTGCTAAAGTGGCGGGCGCTTCGGCCCAGT
CGGGCATCGGAGATTTTCTGAACTTCCTCGCTTATCTGAGTATTAGCCTGGGTGTTCTGAATCTGCTGCCCATTCCCGTC
CTGGACGGGGGGCATTTGCTGTTTTATCTGATCGAGTGGGCGCGTGGTCGCCCCCTTTCGGAAAAGGTTCAAGGTTGGGG
GGCGCAGATCGGTATCAGTCTGGTAGTGGGCGTAATGTTGCTCGCGCTGGTCAACGATCTGGGCCGACTGTAA

Upstream 100 bases:

>100_bases
AGGATGTGAGTGAAAGGGTTGATGTGGTGCGTCAACGGCGGGCCTGGAGGCCTGCAATGATTAACACACTGGCCGACCAG
TCGGTACCCGGAGAAGGCTG

Downstream 100 bases:

>100_bases
AGCGTTGCCGAGTTGCGAATCTGCCGCATTTTGCGGCAGTTTGTTTATTGCCAGTTGGAATAAGAAAGGACTTCATGAAA
CGTCTGCTGCTAACTGCGGT

Product: peptidase M50, putative membrane-associated zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSALYMILGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLLRWHDRQGTEYVVAAIPLGGYVKMLDEREGNVP
PELADQSFNRKTVGQRIAIVIAGPTANFILAIAFFWVLAMMGSEQVRPVIGAVESGSIAQQAGLTAGQEIVAVDGEPTSG
WAGVNLQLVRRLGESGTIALKVRDQGSTVDTSRQLVLSDWLRGAEEPDPIKSLGIRPWRPALLPVLAEIDPKGPAQSAGL
KTGDRLVAMDGQPLDEWQQVVDRVRERPEAKISLRIERDGVQMDVPVTLAAKGEGKAAAGYLGAGVKAVDWPPEMLREVS
YGPFAAMAEGVKRTWNMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGIGDFLNFLAYLSISLGVLNLLPIPV
LDGGHLLFYLIEWARGRPLSEKVQGWGAQIGISLVVGVMLLALVNDLGRL

Sequences:

>Translated_450_residues
MSALYMILGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLLRWHDRQGTEYVVAAIPLGGYVKMLDEREGNVP
PELADQSFNRKTVGQRIAIVIAGPTANFILAIAFFWVLAMMGSEQVRPVIGAVESGSIAQQAGLTAGQEIVAVDGEPTSG
WAGVNLQLVRRLGESGTIALKVRDQGSTVDTSRQLVLSDWLRGAEEPDPIKSLGIRPWRPALLPVLAEIDPKGPAQSAGL
KTGDRLVAMDGQPLDEWQQVVDRVRERPEAKISLRIERDGVQMDVPVTLAAKGEGKAAAGYLGAGVKAVDWPPEMLREVS
YGPFAAMAEGVKRTWNMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGIGDFLNFLAYLSISLGVLNLLPIPV
LDGGHLLFYLIEWARGRPLSEKVQGWGAQIGISLVVGVMLLALVNDLGRL
>Mature_449_residues
SALYMILGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLLRWHDRQGTEYVVAAIPLGGYVKMLDEREGNVPP
ELADQSFNRKTVGQRIAIVIAGPTANFILAIAFFWVLAMMGSEQVRPVIGAVESGSIAQQAGLTAGQEIVAVDGEPTSGW
AGVNLQLVRRLGESGTIALKVRDQGSTVDTSRQLVLSDWLRGAEEPDPIKSLGIRPWRPALLPVLAEIDPKGPAQSAGLK
TGDRLVAMDGQPLDEWQQVVDRVRERPEAKISLRIERDGVQMDVPVTLAAKGEGKAAAGYLGAGVKAVDWPPEMLREVSY
GPFAAMAEGVKRTWNMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGIGDFLNFLAYLSISLGVLNLLPIPVL
DGGHLLFYLIEWARGRPLSEKVQGWGAQIGISLVVGVMLLALVNDLGRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=450, Percent_Identity=47.5555555555556, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48415; Mature: 48284

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALYMILGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLLRWHDRQGTEYVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCEEEE
AAIPLGGYVKMLDEREGNVPPELADQSFNRKTVGQRIAIVIAGPTANFILAIAFFWVLAM
EEECCCHHHHHHHCCCCCCCHHHHCCCCCHHCCCCEEEEEEECCCHHHHHHHHHHHHHHH
MGSEQVRPVIGAVESGSIAQQAGLTAGQEIVAVDGEPTSGWAGVNLQLVRRLGESGTIAL
HCCCHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCEEEE
KVRDQGSTVDTSRQLVLSDWLRGAEEPDPIKSLGIRPWRPALLPVLAEIDPKGPAQSAGL
EECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCC
KTGDRLVAMDGQPLDEWQQVVDRVRERPEAKISLRIERDGVQMDVPVTLAAKGEGKAAAG
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCEEEEECCCCCCCCC
YLGAGVKAVDWPPEMLREVSYGPFAAMAEGVKRTWNMSVLTLDSLKKMLFGELSVKNLSG
HHCCCCEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCC
PITIAKVAGASAQSGIGDFLNFLAYLSISLGVLNLLPIPVLDGGHLLFYLIEWARGRPLS
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCHH
EKVQGWGAQIGISLVVGVMLLALVNDLGRL
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALYMILGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGTPLLRWHDRQGTEYVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCEEEE
AAIPLGGYVKMLDEREGNVPPELADQSFNRKTVGQRIAIVIAGPTANFILAIAFFWVLAM
EEECCCHHHHHHHCCCCCCCHHHHCCCCCHHCCCCEEEEEEECCCHHHHHHHHHHHHHHH
MGSEQVRPVIGAVESGSIAQQAGLTAGQEIVAVDGEPTSGWAGVNLQLVRRLGESGTIAL
HCCCHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCEEEE
KVRDQGSTVDTSRQLVLSDWLRGAEEPDPIKSLGIRPWRPALLPVLAEIDPKGPAQSAGL
EECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCC
KTGDRLVAMDGQPLDEWQQVVDRVRERPEAKISLRIERDGVQMDVPVTLAAKGEGKAAAG
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCEEEEECCCCCCCCC
YLGAGVKAVDWPPEMLREVSYGPFAAMAEGVKRTWNMSVLTLDSLKKMLFGELSVKNLSG
HHCCCCEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCC
PITIAKVAGASAQSGIGDFLNFLAYLSISLGVLNLLPIPVLDGGHLLFYLIEWARGRPLS
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCHH
EKVQGWGAQIGISLVVGVMLLALVNDLGRL
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]