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The map label for this gene is namA [H]

Identifier: 66044547

GI number: 66044547

Start: 1467821

End: 1468927

Strand: Direct

Name: namA [H]

Synonym: Psyr_1299

Alternate gene names: 66044547

Gene position: 1467821-1468927 (Clockwise)

Preceding gene: 66044546

Following gene: 66044549

Centisome position: 24.09

GC content: 62.87

Gene sequence:

>1107_bases
ATGAGCCTGCTGCTTGAACCCTATACCCTGCGTCAATTGACCCTTCGCAATCGCATTGCCGTATCGCCGATGTGCCAGTA
TTCCAGTGTCGACGGCCTGGCCAACGACTGGCACCTGGTTCACCTGGGCAGTCGTGCTGTCGGCGGTGCCGGCCTGGTCA
TCACCGAAGCAATGGCGGTGACGCCGGACGGCCGCATCACTCCCGAAGACCTCGGGCTGTGGAATGACGAGCAGATCGAA
CCGCTGCAACGTATCACCCGCTTCATCAACGCTCAGGGCGCGGTTGCCGGCGTCCAGCTGGCGCATGCCGGCCGCAAGGC
CAGCACCTGGCGCCCGTGGCTTGGCAAGCACGGCAGTATCTCCCTCAATGAAGGTGGCTGGACGCCGGTCGGGCCTTCGG
CGATCGCCTTCGATCCGCAGCACACTGCCCCTGTGCAATTGAGCGAGACGCAGATCCAGGAGTTGATCAAGGCGTTTGTC
GATTCCGCACGGCGTGCCCTGGAGGCAGGCTTCAAAGTCGTGGAAATCCACGCTGCCCATGGCTATTTGCTGCATCAGTT
CCTGTCGCCCCTGAGCAACCAGCGCACCGACGAGTATGGCGGTTCATTCGAGAATCGCATTCGCTTTACGCTGCAAGTCA
CCGAAGCCGTGCGTGCGGTGTGGCCTGCAGAGCTGCCAGTGTTCGTTCGCGTGTCCGCCACCGACTGGGTGGAAGACGGC
TGGAACGCCGATGAAACGGTCGAGCTGGCGCGTCGGTTGAAAGCCATCGGGACCGATCTGATCGATGTATCGTCAGGCGG
TACGTCAGCCAAGGCGGAAATTCCGGTCGGCCCAGGCTACCAGACGCGCTTTGCCGAGCGGGTTCGCAAGGAGTCCGAGA
TCGCAACGGGCACGGTGGGCATGATTACCGATCCGGCGCAGGCAGAGCACATTCTGCGCACCGGGCAGGCCGATATCATC
CTGCTGGCGCGTGAGCTGCTGCGTGATCCGTACTGGCCGCTGCGTGCCGATGAAGACCTGGGTGGGCGCCTGGCAACCTG
GCCTGCGCAGTACCAGCGCGCCACACACCGTGATCAGCCGATTCATGAGTCAGATCTGCGCGACTGA

Upstream 100 bases:

>100_bases
CCCCTCTCGCTAACGGGGTGTCGACACTACACGGTCTGTCAAACCTGTTCTTTGAATGAACGGAACCTGGACACCTGAAT
TTTCATTACGAGAGGTTGCC

Downstream 100 bases:

>100_bases
TCGCCAGTCGGCTCACGGATAGCAATACCCGAAAAATGAGCGCCGTATGGCGCTCATTTTTTGTTACTCGCCTTCCAGCA
GCTCGGTGACGCGGCCGATC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSLLLEPYTLRQLTLRNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVITEAMAVTPDGRITPEDLGLWNDEQIE
PLQRITRFINAQGAVAGVQLAHAGRKASTWRPWLGKHGSISLNEGGWTPVGPSAIAFDPQHTAPVQLSETQIQELIKAFV
DSARRALEAGFKVVEIHAAHGYLLHQFLSPLSNQRTDEYGGSFENRIRFTLQVTEAVRAVWPAELPVFVRVSATDWVEDG
WNADETVELARRLKAIGTDLIDVSSGGTSAKAEIPVGPGYQTRFAERVRKESEIATGTVGMITDPAQAEHILRTGQADII
LLARELLRDPYWPLRADEDLGGRLATWPAQYQRATHRDQPIHESDLRD

Sequences:

>Translated_368_residues
MSLLLEPYTLRQLTLRNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVITEAMAVTPDGRITPEDLGLWNDEQIE
PLQRITRFINAQGAVAGVQLAHAGRKASTWRPWLGKHGSISLNEGGWTPVGPSAIAFDPQHTAPVQLSETQIQELIKAFV
DSARRALEAGFKVVEIHAAHGYLLHQFLSPLSNQRTDEYGGSFENRIRFTLQVTEAVRAVWPAELPVFVRVSATDWVEDG
WNADETVELARRLKAIGTDLIDVSSGGTSAKAEIPVGPGYQTRFAERVRKESEIATGTVGMITDPAQAEHILRTGQADII
LLARELLRDPYWPLRADEDLGGRLATWPAQYQRATHRDQPIHESDLRD
>Mature_367_residues
SLLLEPYTLRQLTLRNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVITEAMAVTPDGRITPEDLGLWNDEQIEP
LQRITRFINAQGAVAGVQLAHAGRKASTWRPWLGKHGSISLNEGGWTPVGPSAIAFDPQHTAPVQLSETQIQELIKAFVD
SARRALEAGFKVVEIHAAHGYLLHQFLSPLSNQRTDEYGGSFENRIRFTLQVTEAVRAVWPAELPVFVRVSATDWVEDGW
NADETVELARRLKAIGTDLIDVSSGGTSAKAEIPVGPGYQTRFAERVRKESEIATGTVGMITDPAQAEHILRTGQADIIL
LARELLRDPYWPLRADEDLGGRLATWPAQYQRATHRDQPIHESDLRD

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=332, Percent_Identity=30.1204819277108, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787939, Length=345, Percent_Identity=29.8550724637681, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17565138, Length=314, Percent_Identity=29.6178343949045, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17559802, Length=262, Percent_Identity=33.206106870229, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=266, Percent_Identity=30.0751879699248, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=283, Percent_Identity=29.6819787985866, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=190, Percent_Identity=33.1578947368421, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=186, Percent_Identity=30.1075268817204, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=267, Percent_Identity=29.9625468164794, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=272, Percent_Identity=32.3529411764706, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=32, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40609; Mature: 40478

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLEPYTLRQLTLRNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVITEAMAV
CCCEECCHHHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEHEEEE
TPDGRITPEDLGLWNDEQIEPLQRITRFINAQGAVAGVQLAHAGRKASTWRPWLGKHGSI
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
SLNEGGWTPVGPSAIAFDPQHTAPVQLSETQIQELIKAFVDSARRALEAGFKVVEIHAAH
EECCCCCCCCCCCCEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHH
GYLLHQFLSPLSNQRTDEYGGSFENRIRFTLQVTEAVRAVWPAELPVFVRVSATDWVEDG
HHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCEEEEEECCHHHHCC
WNADETVELARRLKAIGTDLIDVSSGGTSAKAEIPVGPGYQTRFAERVRKESEIATGTVG
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCE
MITDPAQAEHILRTGQADIILLARELLRDPYWPLRADEDLGGRLATWPAQYQRATHRDQP
EEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHCCCCC
IHESDLRD
CCHHCCCC
>Mature Secondary Structure 
SLLLEPYTLRQLTLRNRIAVSPMCQYSSVDGLANDWHLVHLGSRAVGGAGLVITEAMAV
CCEECCHHHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEHEEEE
TPDGRITPEDLGLWNDEQIEPLQRITRFINAQGAVAGVQLAHAGRKASTWRPWLGKHGSI
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEE
SLNEGGWTPVGPSAIAFDPQHTAPVQLSETQIQELIKAFVDSARRALEAGFKVVEIHAAH
EECCCCCCCCCCCCEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHH
GYLLHQFLSPLSNQRTDEYGGSFENRIRFTLQVTEAVRAVWPAELPVFVRVSATDWVEDG
HHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCEEEEEECCHHHHCC
WNADETVELARRLKAIGTDLIDVSSGGTSAKAEIPVGPGYQTRFAERVRKESEIATGTVG
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCE
MITDPAQAEHILRTGQADIILLARELLRDPYWPLRADEDLGGRLATWPAQYQRATHRDQP
EEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCHHHHHHHCCCCC
IHESDLRD
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA